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Transfer RNA Biogenesis - Betaproteobacteria bacterium GR16-43
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D BWI17_09880 hypothetical protein K01167 rnaSA; ribonuclease T1 [EC:4.6.1.24]
C CCA adding factors
D BWI17_09235 multifunctional CCA tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D BWI17_02180 RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D BWI17_18480 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D BWI17_10820 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D BWI17_08455 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D BWI17_04495 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D BWI17_19980 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D BWI17_01835 glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D BWI17_05660 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D BWI17_14155 lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D BWI17_09010 aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D BWI17_19810 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D BWI17_11650 asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D BWI17_14480 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D BWI17_13870 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D BWI17_19020 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D BWI17_19660 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D BWI17_12720 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D BWI17_14500 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D BWI17_14505 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D BWI17_03000 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D BWI17_22330 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D BWI17_09640 Ala-tRNA(Pro) hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D BWI17_08660 histidine triad nucleotide-binding protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D BWI17_04855 tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D BWI17_19105 tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D BWI17_20115 tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D BWI17_20585 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D BWI17_04445 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D BWI17_10670 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D BWI17_05320 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D BWI17_05335 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D BWI17_19585 selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D BWI17_05305 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D BWI17_01570 rnpB; RNase P RNA component class A K01978 rnpB; RNase P catalytic RNA component
B 3'processing and CCA adding factors
C 3'processing factors
D BWI17_04835 ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D BWI17_05905 hypothetical protein K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D BWI17_09880 hypothetical protein K01167 rnaSA; ribonuclease T1 [EC:4.6.1.24]
C CCA adding factors
D BWI17_09235 multifunctional CCA tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D BWI17_02180 RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D BWI17_06025 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D BWI17_02515 energy-dependent translational throttle protein EttA K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D BWI17_04495 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D BWI17_10820 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D BWI17_03000 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D BWI17_22330 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D BWI17_14480 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D BWI17_08455 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D BWI17_14155 lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D BWI17_19810 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D BWI17_19660 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D BWI17_19980 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D BWI17_13870 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D BWI17_09010 aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D BWI17_03190 glycine--tRNA ligase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D BWI17_03185 glycine--tRNA ligase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D BWI17_19020 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D BWI17_18480 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D BWI17_01835 glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D BWI17_05660 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D BWI17_14500 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D BWI17_14505 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D BWI17_12720 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D BWI17_11650 asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D BWI17_09835 tRNA glutamyl-Q(34) synthetase GluQRS K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D BWI17_09640 Ala-tRNA(Pro) hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D BWI17_20005 tRNA adenosine(34) deaminase TadA K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D BWI17_04305 tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
C Methylthiotransferases
D BWI17_03230 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D BWI17_20605 hypothetical protein K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D BWI17_04855 tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D BWI17_07520 tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D BWI17_05320 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D BWI17_01255 tRNA (uridine(34)/cytosine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D BWI17_22020 hypothetical protein K03437 spoU; RNA methyltransferase, TrmH family
C Psudouridine synthases
D BWI17_19105 tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D BWI17_20115 tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D BWI17_20315 tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D BWI17_09200 tRNA 2-thiocytidine(32) synthetase TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D BWI17_19680 hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D BWI17_20575 iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D BWI17_20585 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D BWI17_22420 hypothetical protein K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D BWI17_05335 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D BWI17_10670 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D BWI17_02825 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D BWI17_22470 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D BWI17_20190 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D BWI17_02710 hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D BWI17_02705 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D BWI17_22165 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D BWI17_10645 tRNA epoxyqueuosine(34) reductase QueG K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D BWI17_19585 selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D BWI17_13900 tRNA 2-selenouridine(34) synthase MnmH K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D BWI17_10755 tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D BWI17_12690 tRNA lysidine(34) synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D BWI17_16845 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D BWI17_04445 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D BWI17_01155 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D BWI17_10650 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
B tRNA degradation factors
C BWI17_12780 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C BWI17_20105 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025