+F Repair protein KO
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DNA Repair and Recombination Proteins - Bacillus sp. JS
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MY9_1482 Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MY9_3892 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MY9_3975 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MY9_0952 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MY9_2239 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MY9_0517 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_3521 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_3065 nucleoside triphosphate phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_0453 MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_1925 putative deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MY9_1482 Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MY9_0186 methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) protein K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D MY9_0187 O6-methylguanine-DNA methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MY9_3892 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MY9_0890 DNA-modified purine glycosidase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MY9_0184 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MY9_3975 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MY9_0952 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MY9_2899 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MY9_2239 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MY9_4229 ExoA K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MY9_2536 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E MY9_3676 YwqL K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E MY9_2744 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MY9_0738 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MY9_2900 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MY9_3560 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E MY9_3561 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E MY9_2839 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E MY9_0737 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_1289 UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_3391 UvrD/Rep family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_2900 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MY9_0738 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MY9_0107 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MY9_0108 RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MY9_0144 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MY9_3799 DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta
F MY9_1715 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MY9_0054 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MY9_1850 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MY9_2847 recombination and DNA strand exchange inhibitor protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MY9_1851 DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MY9_2452 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MY9_2451 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MY9_2917 DNA polymerase III DnaE K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MY9_1805 DNA polymerase III subunit alpha K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MY9_0002 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MY9_2581 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MY9_0031 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MY9_0019 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MY9_0738 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MY9_0737 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_1289 UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_3391 UvrD/Rep family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MY9_4231 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MY9_3697 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MY9_2728 helicase, RecD/TraA family protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MY9_1840 recombinase A K03553 recA; recombination protein RecA
E MY9_2757 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MY9_2756 RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MY9_1717 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MY9_1163 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E MY9_1162 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MY9_1840 recombinase A K03553 recA; recombination protein RecA
E MY9_0086 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MY9_0004 recombination protein F K03629 recF; DNA replication and repair protein RecF
E MY9_1733 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MY9_2744 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MY9_2551 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MY9_0021 recombination protein RecR K06187 recR; recombination protein RecR
E MY9_2445 DNA repair and recombination protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E MY9_2236 Holliday junction-specific endonuclease K03700 recU; recombination protein U
E MY9_2757 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MY9_2756 RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E MY9_1161 ATP-dependent nuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MY9_1160 ATP-dependent nuclease subunit AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MY9_1163 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E MY9_1162 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E MY9_1469 ATP-dependent DNA ligase subunit K10979 ku; DNA end-binding protein Ku
E MY9_1468 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MY9_0007 GyrA K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MY9_0006 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MY9_1758 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MY9_2287 non-specific DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MY9_2744 single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MY9_2551 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MY9_0021 recombination protein RecR K06187 recR; recombination protein RecR
F MY9_0738 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MY9_2103 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MY9_2313 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MY9_3560 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F MY9_3561 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MY9_2406 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MY9_1840 recombinase A K03553 recA; recombination protein RecA
D MY9_1950 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MY9_2445 DNA repair and recombination protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D MY9_4231 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MY9_3697 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MY9_0940 RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D MY9_2848 PHP domain-containing protein K02347 polX; DNA polymerase (family X)
C DNA helicases
D MY9_2219 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MY9_2245 ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MY9_0517 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_3521 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_3065 nucleoside triphosphate phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_0453 MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MY9_1925 putative deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MY9_1889 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MY9_1890 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MY9_2922 oligoribonuclease K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024