+C Two-component system KO
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Two-Component System - Blautia sp. SC05B48
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C EYS05_08350 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C EYS05_02440 two-component sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C EYS05_02445 response regulator transcription factor K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C EYS05_11165 response regulator transcription factor K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C EYS05_13595 response regulator transcription factor K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
C EYS05_03430 HAMP domain-containing histidine kinase K07650 cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
C EYS05_03435 response regulator transcription factor K07770 cssR; two-component system, OmpR family, response regulator CssR
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C EYS05_01885 DUF4118 domain-containing protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C EYS05_01880 response regulator transcription factor K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C EYS05_05400 response regulator transcription factor K07775 resD; two-component system, OmpR family, response regulator ResD
C EYS05_05450 response regulator transcription factor K07775 resD; two-component system, OmpR family, response regulator ResD
C EYS05_10900 response regulator transcription factor K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
C EYS05_03175 HAMP domain-containing histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
C EYS05_13415 HAMP domain-containing histidine kinase K18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C EYS05_10905 HAMP domain-containing protein K18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C EYS05_13410 response regulator transcription factor K18344 vanRB; two-component system, OmpR family, response regulator VanR
B VanS-VanR (VanE type vancomycin resistance)
C EYS05_15680 HAMP domain-containing histidine kinase K18350 vanSC; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C EYS05_13165 HAMP domain-containing histidine kinase K18350 vanSC; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C EYS05_15670 response regulator transcription factor K18349 vanRC; two-component system, OmpR family, response regulator VanR
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
C EYS05_02565 HAMP domain-containing histidine kinase K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
C EYS05_15875 HAMP domain-containing histidine kinase K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
C EYS05_02560 response regulator transcription factor K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR
C EYS05_15870 response regulator transcription factor K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR
B Unclassified
C EYS05_01985 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C EYS05_06995 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C EYS05_16050 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C EYS05_07830 winged helix-turn-helix transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C EYS05_12710 spo0A; sporulation transcription factor Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C EYS05_08220 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C EYS05_11715 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_02215 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_02260 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_04440 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_08690 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_01495 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_11330 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_08185 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_12470 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EYS05_11710 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_02210 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_02265 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_09745 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_04445 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_08695 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_11325 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_08180 response regulator K07720 yesN; two-component system, response regulator YesN
C EYS05_01500 response regulator K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C EYS05_00165 transporter substrate-binding domain-containing protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
C EYS05_00715 ANTAR domain-containing protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C EYS05_00170 response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023