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Mitochondrial Biogenesis - Babesia microti
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
D B661_mgp03 cob; apocytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D B661_mgp02 cox1; cytochrome c oxidase subunit I K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D BMR1_03g03415 cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
C F-type ATPase
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D BmR1_04g09005 DNA-directed RNA polymerase, mitochondrial K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
C Mitochondrial translation factors
D BMR1_02g04235 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D BMR1_02g01720 elongation factor EF-Tu K02358 tuf; elongation factor Tu
D BMR1_02g01065 Elongation factor Tu GTP binding domain K02355 fusA; elongation factor G
D BmR1_04g09525 elongation factor EF-G K02355 fusA; elongation factor G
C RNase MRP
D BmR1_04g09640 POP1, ribonuclease P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D BmR1_04g09205 POP4, RPP29, ribonuclease P protein subunit POP4 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D BmR1_04g07330 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
C Other mitochondrial DNA transcription and translation factors
D BmR1_04g08550 Lactation elevated protein 1 K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D BMR1_03g04575 splicing factor 1 K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D BMR1_01G02590 solute carrier family 25 (mitochondrial carrier, adenine nucleotide) K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D BmR1_04g09410 mitochondrial carrier protein, MC family K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D BmR1_04g06780 GTPase Era K03595 era; GTPase
D BMR1_01G00295 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D BmR1_04g06445 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D BMR1_01G01655 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D BMR1_03g00240 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D BMR1_01G00100 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D BMR1_03g02600 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D BmR1_04g09180 GatB/GatE catalytic domain K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D BmR1_04g09945 2'5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
D BMR1_01G00535 Ribosome biogenesis GTPase A K19828 MTG1; mitochondrial GTPase 1
D BmR1_04g07090 Mitochondrial ribosome-associated GTPase 1 K19828 MTG1; mitochondrial GTPase 1
D BMR1_02g00533 Probable peptide chain release factor C12orf65 mitochondrial K23498 COXPD7; peptide chain release factor
D BmR1_04g06530 UPF0160 protein MYG1 mitochondrial K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
C Mitochondrial DNA maintenance factors
C Other Mitochondrial DNA replication factors
D BMR1_01G03165 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BMR1_02g01695 ATPase family AAA domain-containing protein 3 K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D BMR1_03g00965 DnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D BMR1_01G02545 HSPA1_8, heat shock 70kDa protein 1/8 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
B Outer membrane
C Transporter outer membrane (TOM) complex
D BmR1_04g09755 mitochondrial import receptor subunit TOM40 K11518 TOM40; mitochondrial import receptor subunit TOM40
D BMR1_01G02355 mitochondrial import receptor subunit TOM22, putative (TOM22) K17769 TOM22; mitochondrial import receptor subunit TOM22
C TOB/SAM complex
D BmR1_04g09565 Sorting and assembly machinery component 50 homolog A K07277 SAM50; outer membrane protein insertion porin family
C Porin
C ERMES complex
C Other outer membrane factor
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D BMR1_03g03835 Mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D BMR1_03g00835 Mitochondrial import inner membrane translocase subunit Tim10 K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
C TIM8/13 complex
D BMR1_02g01668 mitochondrial import inner membrane translocase subunit TIM13, putative (TIM13) K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D BMR1_02g03802 mitochondrial inner membrane TIM10 associated protein, putative K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D BMR1_02g02015 conserved Plasmodium protein, unknown function K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
D BMR1_03g02000 Mitochondrial FAD-linked sulfhydryl oxidase ERV1 K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
C MICOS complex (yeast)
C TIM22 complex
D BmR1_04g05165 Mitochondrial import inner membrane translocase subunit tim22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D BMR1_03g03535 mitochondrial import inner membrane translocase subunit TIM23, putative (TIM23) K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D BMR1_03g00755 Tim17/Tim22/Tim23/Pmp24 family K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D BMR1_02g02090 NLI interacting factor-like phosphatase K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
C Other inner membrane factors
D BMR1_02g03905 LETM1-like protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D BMR1_02g03240 mitochondrial inner membrane protease subunit 1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D BmR1_04g05170 Uncharacterized methyltransferase C3B9.04 mitochondrial K17803 OMS1; methyltransferase OMS1, mitochondrial [EC:2.1.1.-]
D BMR1_03g04355 Uncharacterised protein family (UPF0041) K22138 MPC1; mitochondrial pyruvate carrier 1
D BMR1_02g01667 Mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
B Matrix
C MMC/PAM proteins
D BMR1_03g00750 Mitochondrial import inner membrane translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D BmR1_04g08040 molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D BMR1_03g00730 molecular chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D BMR1_03g02315 protein pelota K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D BmR1_04g08505 mitochondrial processing peptidase K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D BMR1_02g00260 mitochondrial processing peptidase K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D BMR1_03g00560 mitochondrial intermediate peptidase K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D BMR1_03g04270 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D BMR1_03g03315 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D BMR1_02g00395 chaperonin GroES K04078 groES; chaperonin GroES
D BMR1_01G02830 molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D BMR1_02g02565 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D BMR1_02g01065 Elongation factor Tu GTP binding domain K02355 fusA; elongation factor G
D BmR1_04g09525 elongation factor EF-G K02355 fusA; elongation factor G
C Nuclear respiratory factors
C Coactivators
C Proteins involved in Fe-S cluster biogenesis
D BMR1_03g04230 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D BMR1_02g00446 nitrogen fixation protein NifU and related proteins K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D BMR1_02g01335 protein ISD11, putative (ISD11) K22069 LYRM4; LYR motif-containing protein 4
D BMR1_02g00365 2Fe-2S ferredoxin K22071 FDX2; ferredoxin-2, mitochondrial
D BMR1_03g00286 ferredoxin--NADP+ reductase K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D BmR1_04g08040 molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D BMR1_01G02321 Iron-sulfur cluster co-chaperone protein HscB mitochondrial K04082 hscB; molecular chaperone HscB
D BMR1_02g02145 Monothiol glutaredoxin-S11 K07390 grxD; monothiol glutaredoxin
D BmR1_04g06260 iron-sulfur cluster assembly protein K22063 ISCA1; iron-sulfur cluster assembly 1
D BmR1_04g07630 Iron-sulfur assembly protein IscA-like 2 mitochondrial K22072 ISCA2; iron-sulfur cluster assembly 2
D BMR1_03g04682 Putative transferase CAF17 mitochondrial K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D BmR1_04g06390 NifU-like protein C1709.19c K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
C Other regulator of mitochondrial biogenesis
D BmR1_04g06650 Protein tyrosine kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D BMR1_03g02710 Protein SERAC1 K23504 SERAC1; protein SERAC1
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
C Complex-II assembly factors
C Complex-III assembly factors
D BMR1_02g00285 BCS1 N terminal K08900 BCS1; mitochondrial chaperone BCS1
C Complex-IV assembly factors
D BMR1_02g03022 cytochrome c oxidase assembly protein, putative K18178 COA5; cytochrome c oxidase assembly factor 5
D BmR1_04g08725 ATP-dependent RNA helicase DDX23/PRP28 K02257 COX10; heme o synthase [EC:2.5.1.141]
D BMR1_02g00065 cytochrome c oxidase subunit XI assembly protein K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D BmR1_04g05520 cytochrome c oxidase subunit XV assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D BMR1_01G01250 cytochrome c oxidase subunit XVII assembly protein K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D BmR1_04g09135 hypothetical protein K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D BMR1_03g01435 Cytochrome c oxidase assembly protein COX19 K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D BMR1_01G01645 preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D BMR1_02g03835 SURF1 family K14998 SURF1; surfeit locus 1 family protein
D BmR1_04g08740 sco1/2-like protein K07152 SCO1; protein SCO1
C Complex-V assembly factors
D BMR1_03g00305 ATP synthase mitochondrial F1 complex assembly factor 1 K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
B Mitochondrial dynamics
C Fission and Fusion factors
D BmR1_04g09231 Optic atrophy 3 protein (OPA3) K23166 OPA3; optic atrophy 3 protein
D BMR1_01G02575 dynamin GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D BMR1_02g02560 mitochondrial fission 1 protein, putative (FIS1) K17969 FIS1; mitochondrial fission 1 protein
C Actin cytoskeleton organization
D BmR1_04g06305 peptide alpha-N-acetyltransferase K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
C Mitochondrial movement
D BMR1_01G01640 Prohibitin-4 mitochondrial K17080 PHB1; prohibitin 1
D BMR1_02g00405 Prohibitin-2 K17081 PHB2; prohibitin 2
C Retention of mitochondria
D BMR1_01G02575 dynamin GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D BMR1_03g01547 Myosin-13 K10357 MYO5; myosin V
D BMR1_03g03720 myosin ATPase K10357 MYO5; myosin V
C Morphogenesis factors
D BMR1_02g00230 Mitochondrial ribosomal death-associated protein 3 K17408 DAP3; small subunit ribosomal protein S29
B Mitophagy factors
C Autophagy-related proteins
D BMR1_01G01105 autophagy-related protein 3, putative (ATG3) K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D BMR1_03g00700 autophagy-related protein 7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D BMR1_03g03150 GABA(A) receptor-associated protein (autophagy-related protein 8) K08341 GABARAP; GABA(A) receptor-associated protein
C Parkin-dependent mechanism factors
D BMR1_02g03135 conserved Plasmodium protein, unknown function K19513 CLEC16A; protein CLEC16A
C Parkin-independent mechanism factors
D BmR1_04g08775 molecular chaperone HtpG K04079 HSP90A; molecular chaperone HtpG
C Other mitophagy factors
D BmR1_04g06650 Protein tyrosine kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024