+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Bosea sp. Tri-49</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      BLM15_14700 modification methylase	K13581 ccrM; modification methylase [EC:2.1.1.72] 
D      BLM15_08760 hypothetical protein	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
C    BLM15_06065 hypothetical protein	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-] 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      BLM15_11650 AbrB family transcriptional regulator	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      BLM15_28880 phosphatidylinositol kinase	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      BLM15_29935 phosphatidylinositol kinase	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
C    HicA-HicB
C    YafO-YafN
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      BLM15_11050 plasmid stabilization protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      BLM15_30285 plasmid stabilization protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      BLM15_11055 CopG family transcriptional regulator	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
D      BLM15_29715 prevent-host-death protein	K19165 phd; antitoxin Phd 
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      BLM15_14045 hypothetical protein	K19686 vapC28S; ribonuclease VapC28/30/34/36/42 [EC:3.1.-.-] 
D      BLM15_15020 hypothetical protein	K19686 vapC28S; ribonuclease VapC28/30/34/36/42 [EC:3.1.-.-] 
D      BLM15_14040 histidinol dehydrogenase	K19687 vapB28S; antitoxin VapB28/30/34/36/42 
D      BLM15_15015 hypothetical protein	K19687 vapB28S; antitoxin VapB28/30/34/36/42 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      BLM15_29710 VapC toxin family PIN domain ribonuclease	K07062 fitB; toxin FitB [EC:3.1.-.-] 
C    BC_0920-BC_0921
C    SpoIISA-SpoIISB
C    Tse6-Tsi6
C    Type II TA system related factors
D      BLM15_01375 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      BLM15_10330 DNA topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      BLM15_06610 DNA topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      BLM15_05725 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
D      BLM15_11220 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      BLM15_05935 succinate dehydrogenase assembly factor 2	K09159 cptB; antitoxin CptB 
C    AbiEii-AbiEi
B  Type V TA system
C    GhoT-GhoS
C    Other GhoT/OrtT toxin family protein
B  Type VI TA system
C    SocB-SocA
B  Type VII TA system
C    Hha-TomB
C    TglT-TakA
C    HepT-MntA
B  Type VIII TA system
C    SdsR-RyeA
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    BLM15_05490 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: May 19, 2025