+F Repair protein KO
#
DNA Repair and Recombination Proteins - Butyrivibrio proteoclasticus
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E bpr_I1242 ung1; uracil-DNA glycosylase Ung1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E bpr_II288 ung2; uracil-DNA glycosylase Ung2 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E bpr_I2818 ogg; 8-oxoguanine DNA glycosylase Ogg K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E bpr_I2085 nth; endonuclease III Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E bpr_I2158 Rad3-related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D bpr_I0727 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I1949 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2141 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2353 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2710 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2778 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I1498 dut; dUTP diphosphatase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E bpr_I1242 ung1; uracil-DNA glycosylase Ung1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E bpr_II288 ung2; uracil-DNA glycosylase Ung2 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E bpr_I2085 nth; endonuclease III Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E bpr_III162 xth; exodeoxyribonuclease III Xth K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E bpr_I1995 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E bpr_II305 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E bpr_I1416 ligA1; NAD-dependent DNA ligase LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E bpr_II163 ligA2; NAD-dependent DNA ligase LigA2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E bpr_I2597 uvrA; excinuclease ABC A subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E bpr_I2598 uvrB; excinuclease ABC B subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E bpr_I0094 uvrC; excinuclease ABC C subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E bpr_I0764 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I0989 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I1496 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I1909 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I2258 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_II238 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_II346 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_III062 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I1416 ligA1; NAD-dependent DNA ligase LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E bpr_II163 ligA2; NAD-dependent DNA ligase LigA2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F bpr_I2369 rpoB; DNA directed RNA polymerase beta subunit RpoB K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F bpr_I2368 rpoC; DNA directed RNA polymerase beta-prime subunit RpoC K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F bpr_I0623 rpoA; DNA-directed RNA polymerase alpha subunit RpoA K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F bpr_I1283 rpoZ; DNA-directed RNA polymerase omega subunit RpoZ K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F bpr_I0294 mfd; transcription-repair coupling factor Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E bpr_I1491 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E bpr_I2834 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E bpr_I1490 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E bpr_I0980 xseA; exodeoxyribonuclease VII large subunit XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E bpr_I0981 xseB; exodeoxyribonuclease VII small subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E bpr_I2768 dnaE1; DNA polymerase III E DnaE1 K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E bpr_II264 dnaE2; DNA polymerase III E DnaE2 K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E bpr_IV130 DNA polymerase III-associated protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E bpr_I0960 polC1; DNA polymerase III C PolC1 K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E bpr_IV123 polC2; DNA polymerase III C polC2 K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E bpr_I0002 dnaN; DNA polymerase III beta subunit DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E bpr_I1801 holA; DNA polymerase III delta subunit HolA K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E bpr_I0086 holB; DNA polymerase III delta' subunit HolB K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E bpr_II254 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E bpr_I0225 dnaX1; DNA polymerase III gamma and tau subunits DnaX1 K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E bpr_IV131 dnaX2; DNA polymerase III gamma and tau subunits DnaX2 K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E bpr_I1416 ligA1; NAD-dependent DNA ligase LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E bpr_II163 ligA2; NAD-dependent DNA ligase LigA2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E bpr_I0764 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I0989 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I1496 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I1909 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I2258 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_II238 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_II346 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_III062 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E bpr_I0240 ssb1; single-stranded DNA binding protein Ssb1 K03111 ssb; single-strand DNA-binding protein
E bpr_II423 ssb3; single stranded DNA binding protein Ssb3 K03111 ssb; single-strand DNA-binding protein
E bpr_IV047 ssb4; single stranded DNA-binding protein Ssb4 K03111 ssb; single-strand DNA-binding protein
E bpr_I1911 vsr; DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E bpr_I2592 recD; exodeoxyribonuclease V alpha subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E bpr_II324 helicase RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E bpr_IV188 helicase RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E bpr_I1639 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA
E bpr_I1649 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E bpr_I1648 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E bpr_I1993 priA; primosomal protein N' PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E bpr_I0323 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E bpr_I0322 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E bpr_I1639 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA
E bpr_I0636 hypothetical protein K04485 radA; DNA repair protein RadA/Sms
E bpr_I0875 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E bpr_I0004 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E bpr_I0644 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E bpr_I1463 recG1; ATP-dependent DNA helicase RecG1 K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E bpr_II085 divergent AAA domain-containing protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E bpr_II313 recG2; ATP-dependent DNA helicase RecG2 K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E bpr_I1995 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E bpr_II305 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E bpr_I1218 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E bpr_I0227 recR; recombinational DNA repair protein RecR K06187 recR; recombination protein RecR
E bpr_I0987 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E bpr_I1452 recU; recombination protein U RecU K03700 recU; recombination protein U
E bpr_I1649 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E bpr_I1648 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E bpr_I0735 addA; ATP-dependent nuclease subunit A AddA K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E bpr_I0734 addB; ATP-dependent nuclease subunit B AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E bpr_I0323 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E bpr_I0322 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E bpr_I1678 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F bpr_I0006 gyrA; DNA gyrase subunit A GyrA K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F bpr_I1460 parC; DNA topoisomerase IV subunit A ParC K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F bpr_I0005 gyrB; DNA gyrase subunit B GyrB K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F bpr_I1461 parE; DNA topoisomerase IV subunit B ParE K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F bpr_I1353 topA; DNA topoisomerase I TopA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F bpr_I1070 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F bpr_II236 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F bpr_III252 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F bpr_IV068 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F bpr_I1995 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F bpr_II305 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F bpr_I1218 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F bpr_I0227 recR; recombinational DNA repair protein RecR K06187 recR; recombination protein RecR
F bpr_I1416 ligA1; NAD-dependent DNA ligase LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F bpr_II163 ligA2; NAD-dependent DNA ligase LigA2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F bpr_I2597 uvrA; excinuclease ABC A subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F bpr_I2598 uvrB; excinuclease ABC B subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D bpr_I1736 UmuC-like DNA repair protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D bpr_I0022 UmuC-like DNA repair protein K03502 umuC; DNA polymerase V
D bpr_IV158 UmuC-like DNA repair protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D bpr_I1639 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA
D bpr_I1435 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D bpr_I0987 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D bpr_I0240 ssb1; single-stranded DNA binding protein Ssb1 K03111 ssb; single-strand DNA-binding protein
D bpr_II423 ssb3; single stranded DNA binding protein Ssb3 K03111 ssb; single-strand DNA-binding protein
D bpr_IV047 ssb4; single stranded DNA-binding protein Ssb4 K03111 ssb; single-strand DNA-binding protein
D bpr_I1923 DNA-damage-inducible protein K14623 dinD; DNA-damage-inducible protein D
D bpr_I1638 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D bpr_I0727 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I1949 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2141 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2353 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2710 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I2778 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D bpr_I1498 dut; dUTP diphosphatase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D bpr_I0968 DHH domain-containing protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D bpr_I1433 DHH domain-containing protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025