+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Burkholderia pseudomallei 1710b

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D BURPS1710b_2077 mbtH-like protein K05375 mbtH; MbtH protein D BURPS1710b_2147 mbtH-like protein K05375 mbtH; MbtH protein D BURPS1710b_A0270 mbtH-like protein-related protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase D BURPS1710b_A2148 pchD; salicyl-AMP ligase K12238 pchD; salicylate---[aryl-carrier protein] ligase [EC:6.2.1.61] D BURPS1710b_A2150 pchE; pyochelin synthetase K12239 pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69] D BURPS1710b_A2151 pchF; pyochelin synthetase K12240 pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase B Methylase B Glycosyltransferase B Halogenase C BURPS1710b_A0003 prnC; halogenase PrnC K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-] C BURPS1710b_A1117 prnC; PrnC K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-] C BURPS1710b_A0147 syrB2; CmaB K15650 cmaB; non-haem Fe2+, alpha-ketoglutarate-dependent halogenase C BURPS1710b_A0897 barB2; BarB2 K15650 cmaB; non-haem Fe2+, alpha-ketoglutarate-dependent halogenase B beta-Branched incorporating proteins C BURPS1710b_A1850 fabD; malonyl CoA-acyl carrier protein transacylase K15327 pksC; polyketide biosynthesis malonyl-CoA-[acyl-carrier-protein] transacylase C BURPS1710b_A2609 pksF; beta-ketoacyl synthase K00646 pksF; malonyl-[acp] decarboxylase [EC:4.1.1.124] C BURPS1710b_A2610 acyl carrier protein acpK K15337 acpK; polyketide biosynthesis acyl carrier protein C BURPS1710b_A2613 putative hydroxymethylglutaryl-coenzyme A synthase K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C BURPS1710b_A2612 pksH; polyketide biosynthesis enoyl-CoA hydratase K15312 pksH; 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase [EC:4.2.1.181] C BURPS1710b_A2611 enoyl-CoA hydratase/isomerase family protein domain protein K15313 pksI; 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase [EC:4.1.1.125] B Others # ANonribosomal peptide tailoring proteins B Reductase C BURPS1710b_A2152 pchG; pyochelin biosynthetic protein K12241 pchG; pyochelin biosynthesis protein PchG B Thioesterase C BURPS1710b_A2147 pchC; pyochelin biosynthetic protein K12242 pchC; pyochelin biosynthesis protein PchC B Oxygenase B Glycosyltransferase B Aminotransferase B Others C BURPS1710b_A2417 cefD; putative aminotransferase class-V K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024