+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Burkholderia pseudomallei MSHR511
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C BBQ_2540 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C BBQ_293 type IV leader peptidase family protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C BBQ_3922 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
C BBQ_1683 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
C BBQ_1768 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C BBQ_1208 guaA; GMP synthase (glutamine-hydrolyzing), N-terminal domain protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C BBQ_3406 peptidase C26 family protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C BBQ_5724 peptidase C26 family protein K07010 K07010; putative glutamine amidotransferase
C BBQ_974 peptidase C26 family protein K07010 K07010; putative glutamine amidotransferase
C BBQ_768 peptidase C26 family protein K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
C BBQ_199 ABC transporter family protein K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
C BBQ_4874 ABC transporter family protein K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
B Family C40
B Family C44
C BBQ_4450 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C BBQ_135 glutamine amidotransferases class-II family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C BBQ_2134 glmS; glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C BBQ_4114 glmS; glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C BBQ_3114 glmS; glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C BBQ_2910 SIS domain protein K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C BBQ_5517 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C BBQ_6051 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C BBQ_1442 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C BBQ_2745 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C BBQ_2800 intracellular protease, PfpI family protein K05520 yhbO; deglycase [EC:3.5.1.124]
C BBQ_4269 thiJ/PfpI family protein K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
C BBQ_1195 hypothetical protein K25587 E3.4.17.25; glutathione-S-conjugate glycine hydrolase [EC:3.4.17.25]
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C BBQ_5112 CAAX protease self-immunity family protein K07052 K07052; CAAX protease family protein
C BBQ_4265 CAAX protease self-immunity family protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C BBQ_203 peptidase M1 family protein K01256 pepN; aminopeptidase N [EC:3.4.11.2]
C BBQ_759 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
B Family M3
C BBQ_4993 peptidase M3 family protein K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C BBQ_1008 peptidase M3 family protein K01414 prlC; oligopeptidase A [EC:3.4.24.70]
B Family M4: thermolysin family
C BBQ_4593 thermolysin metallopeptidase, catalytic domain protein K20273 zmpA; zinc metalloprotease ZmpA
C BBQ_5630 peptidase propeptide and YPEB domain protein K20274 zmpB; zinc metalloprotease ZmpB
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
C BBQ_5528 collagenase family protein K01387 colA; microbial collagenase [EC:3.4.24.3]
C BBQ_5310 collagenase family protein K01387 colA; microbial collagenase [EC:3.4.24.3]
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C BBQ_5181 ddpX; D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
C BBQ_196 D-alanyl-D-alanine carboxypeptidase family protein K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
B Family M16: pitrilysin family
B Family M17: leucyl aminopeptidase family
C BBQ_2481 cytosol aminopeptidase family, N-terminal domain protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C BBQ_5646 membrane dipeptidase family protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C BBQ_1164 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C BBQ_5937 amidohydrolase family protein K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
C BBQ_6066 amidohydrolase family protein K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
B Family M23
C BBQ_5613 peptidase M23 family protein K08642 lasA; LasA protease [EC:3.4.24.-]
B Family M24
C BBQ_1120 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C BBQ_1176 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C BBQ_222 metallopeptidase M24 family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
C BBQ_416 aminopeptidase P, N-terminal domain protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
C BBQ_2204 metallopeptidase M24 family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C BBQ_5631 peptidase M20/M25/M40 family protein K05994 E3.4.11.10; bacterial leucyl aminopeptidase [EC:3.4.11.10]
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C BBQ_5056 hflB; ATP-dependent metallopeptidase HflB family protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
C BBQ_2086 hflB; ATP-dependent metallopeptidase HflB family protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C BBQ_820 peptidase M48 family protein K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
C BBQ_3261 peptidase M48 family protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C BBQ_2662 peptidase M48 family protein K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C BBQ_1184 rseP; RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
C BBQ_4853 D-aminopeptidase family protein K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
C BBQ_1362 phosphoenolpyruvate:glucose-phosphotransferase regulator family protein K09933 mtfA; MtfA peptidase
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
C BBQ_5394 dmpA; D-aminopeptidase K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
C BBQ_4852 peptidase S58 family protein K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C BBQ_874 peptidase Do family protein K04771 degP; serine protease Do [EC:3.4.21.107]
C BBQ_2640 peptidase Do family protein K04771 degP; serine protease Do [EC:3.4.21.107]
C BBQ_1877 PDZ domain protein K04771 degP; serine protease Do [EC:3.4.21.107]
C BBQ_169 peptidase Do family protein K04772 degQ; serine protease DegQ [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C BBQ_5160 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
C BBQ_4135 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C BBQ_4807 prolyl oligopeptidase, N-terminal beta-propeller domain protein K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C BBQ_4928 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C BBQ_3001 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C BBQ_5743 D-alanyl-D-alanine carboxypeptidase family protein K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
C BBQ_2394 D-alanyl-D-alanine carboxypeptidase family protein K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
C BBQ_1016 D-alanyl-D-alanine carboxypeptidase family protein K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C BBQ_2643 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C BBQ_1266 clpP; ATP-dependent Clp endopeptidase, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
C BBQ_5537 hydrolase CocE/NonD family protein K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
C BBQ_4136 hydrolase CocE/NonD family protein K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
B Family S16: lon protease family
C BBQ_1268 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C BBQ_3184 AAA domain family protein K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C BBQ_1704 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C BBQ_877 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C BBQ_6011 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C BBQ_799 PGAP1-like family protein K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
B Family S41: C-terminal processing peptidase family
C BBQ_2966 C-terminal processing peptidase family protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
C BBQ_6012 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C BBQ_1570 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C BBQ_1434 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C BBQ_2697 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C BBQ_859 clp protease family protein K04773 sppA; protease IV [EC:3.4.21.-]
B Family S50
B Family S51
B Family S53
C BBQ_4404 pcp; pseudomonalisin K05998 E3.4.21.100; pseudomonalisin [EC:3.4.21.100]
C BBQ_1194 pcp; pseudomonalisin K05998 E3.4.21.100; pseudomonalisin [EC:3.4.21.100]
C BBQ_4155 pcp; pseudomonalisin K05999 E3.4.21.101; xanthomonalisin [EC:3.4.21.101]
C BBQ_4586 scpA; kumamolisin-As K08677 kscP; kumamolisin [EC:3.4.21.123]
B Family S54: Rhomboid family
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C BBQ_1214 ldcA; murein tetrapeptide carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C BBQ_3227 hslV; ATP-dependent protease HslVU, peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C BBQ_4847 iaaA; isoaspartyl peptidase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C BBQ_4870 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C BBQ_2993 gamma-glutamyltranspeptidase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C BBQ_2735 gamma-glutamyltranspeptidase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C BBQ_951 peptidase U32 family protein K24845 ubiV; O2-independent ubiquinone biosynthesis protein UbiV
C BBQ_950 hypothetical protein K24844 ubiU; O2-independent ubiquinone biosynthesis protein UbiU
B Family U62
C BBQ_824 modulator of DNA gyrase family protein K03592 pmbA; PmbA protein
C BBQ_472 modulator of DNA gyrase family protein K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
C BBQ_2395 ecotin family protein K08276 eco; ecotin
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C BBQ_5322 MG2 domain protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C BBQ_1391 hflC; HflC protein K04087 hflC; modulator of FtsH protease HflC
C BBQ_1390 hflK; HflK protein K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS