+F Repair protein KO
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DNA Repair and Recombination Proteins - Bradyrhizobium cosmicum
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D S23_63690 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_67050 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_68940 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_29700 DNA photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E S23_37060 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E S23_54870 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E S23_01470 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D S23_05970 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_16790 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_30850 MutT family NTP pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_54230 nudD; putative Nudix hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_00750 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D S23_63690 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_67050 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_68940 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D S23_01490 transcriptional regulatory protein AraC family K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D S23_29700 DNA photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D S23_50200 hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D S23_50480 alkB; alkylated DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E S23_16490 putative glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E S23_31430 putative uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E S23_49770 putative uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E S23_54610 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E S23_64230 alkA; DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E S23_37060 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E S23_54870 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E S23_54290 tag; 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E S23_00710 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E S23_01470 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E S23_02190 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E S23_34030 exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E S23_41910 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E S23_39020 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E S23_17290 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E S23_66670 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E S23_18850 uvrA; putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E S23_34520 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E S23_60490 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E S23_61010 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E S23_17720 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_28240 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_61310 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_66670 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E S23_17290 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F S23_28700 RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F S23_28710 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F S23_29040 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F S23_31450 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F S23_35150 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
F S23_46570 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E S23_68880 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E S23_61250 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E S23_61370 putative exonuclease VII containing large subunit OB-fold nucleic acid binding domain K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E S23_53200 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E S23_33240 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E S23_00020 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E S23_41530 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E S23_02090 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E S23_36130 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E S23_01960 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E S23_66450 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E S23_17290 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E S23_17720 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_28240 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_61310 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E S23_34570 ssb; single-strand DNA binding protein RecBCD nuclease K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E S23_24880 recA; recombinase A K03553 recA; recombination protein RecA
E S23_11140 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E S23_11160 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E S23_11130 ruvC; probable holliday junction nuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E S23_03980 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E S23_24880 recA; recombinase A K03553 recA; recombination protein RecA
E S23_42030 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E S23_00030 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF
E S23_35130 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E S23_39020 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E S23_31530 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E S23_66430 recR; recombination protein RecR K06187 recR; recombination protein RecR
E S23_17280 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E S23_11140 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E S23_11160 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E S23_11130 ruvC; probable holliday junction nuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E S23_00810 putative helicase 2 K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E S23_00800 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E S23_49350 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E S23_15380 hypothetical protein K10979 ku; DNA end-binding protein Ku
E S23_48830 putative ATP-dependent DNA ligase protein K10979 ku; DNA end-binding protein Ku
E S23_15390 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F S23_34580 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F S23_00060 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F S23_02600 putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F S23_31060 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F S23_32550 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F S23_37940 histone-like protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F S23_39020 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F S23_31530 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F S23_66430 recR; recombination protein RecR K06187 recR; recombination protein RecR
F S23_17290 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F S23_31910 ihfA; integration host factor alpha subunit K04764 ihfA; integration host factor subunit alpha
F S23_00910 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F S23_05520 helicase-like protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F S23_05650 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F S23_18850 uvrA; putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F S23_34520 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F S23_60490 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F S23_62560 putative regulator protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D S23_30870 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D S23_69270 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D S23_24880 recA; recombinase A K03553 recA; recombination protein RecA
D S23_21580 putative LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D S23_33520 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D S23_17280 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D S23_49750 hypothetical protein K14160 imuA; protein ImuA
D S23_49740 putative DNA-directed DNA polymerase K14161 imuB; protein ImuB
D S23_49730 dnaE; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D S23_34570 ssb; single-strand DNA binding protein RecBCD nuclease K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D S23_66740 lhr; putative ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D S23_05970 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_16790 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_30850 MutT family NTP pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_54230 nudD; putative Nudix hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D S23_00750 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D S23_40100 vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025