+F Repair protein KO
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DNA Repair and Recombination Proteins - Bacillus subtilis QB928
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D B657_13540 ogt; O6-alkylguanine DNA alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E B657_37970 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E B657_38620 aag; 3-alkylated purines and hypoxanthine DNAglycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E B657_08630 mutY; A/G-specific adenine glycosylase or DNA-(apurinicor apyrimidinic site) lyase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E B657_22340 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D B657_34780 yvcI; Putative triphosphate pyrophosphate hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_30630 ytkD; Nucleoside triphosphate phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_04330 mutT; Putative NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_20020 yosS; SPbeta phage deoxyuridine 5'-triphosphatenucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D B657_17660 yncF; Deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D B657_13540 ogt; O6-alkylguanine DNA alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D B657_01810 adaA; Methylphosphotriester-DNA alkyltransferase andtranscriptional K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D B657_01820 adaB; O6-methylguanine-DNA methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E B657_37970 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E B657_08010 yfjP; Putative DNA-modified purine glycosidase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E B657_01800 alkA; DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E B657_38620 aag; 3-alkylated purines and hypoxanthine DNAglycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E B657_08630 mutY; A/G-specific adenine glycosylase or DNA-(apurinicor apyrimidinic site) lyase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E B657_29080 mutM; Formamidopyrimidine-DNA glycosidase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E B657_22340 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E B657_40880 exoA; Apurinic/apyrimidinic endonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E B657_25130 nfo; Type IV apurinic/apyrimidinic endonuclease K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E B657_36170 ywqL; Putative deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E B657_27620 recJ; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E B657_20350 yorK; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E B657_06620 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E B657_29090 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E B657_35160 uvrA; Excinuclease ABC (subunit A) K03701 uvrA; excinuclease ABC subunit A
E B657_35170 uvrB; Excinuclease ABC (subunit B) K03702 uvrB; excinuclease ABC subunit B
E B657_28490 uvrC; Excinuclease ABC (subunit C) K03703 uvrC; excinuclease ABC subunit C
E B657_11820 yjcD; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_06610 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_33450 helD; DNA 3'-5' helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_29090 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E B657_06620 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F B657_01070 rpoB; RNA polymerase (beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F B657_01080 rpoC; RNA polymerase (beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F B657_01430 rpoA; RNA polymerase (alpha subunit) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F B657_37160 rpoE; RNA polymerase (delta subunit) K03048 rpoE; DNA-directed RNA polymerase subunit delta
F B657_15690 rpoZ; Omega subunit of RNA polymerase K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F B657_00550 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E B657_17040 mutS; DNA mismatch repair recognition factor K03555 mutS; DNA mismatch repair protein MutS
E B657_28580 mutSB; Putative DNA mismatch repair enzyme K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E B657_17050 mutL; DNA mismatch repair factor K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E B657_24300 xseA; Exodeoxyribonuclease VII (large subunit) K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E B657_24290 xseB; Exodeoxyribonuclease VII (small subunit) K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E B657_20340 yorL; Putative DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E B657_29230 dnaE; DNA polymerase III (alpha subunit) K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E B657_16580 polC; DNA polymerase III (alpha subunit) K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E B657_00020 dnaN; DNA polymerase III (beta subunit) K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E B657_00310 holB; DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E B657_00190 dnaX; DNA polymerase III (gamma and tau subunits) K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E B657_06620 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E B657_11820 yjcD; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_06610 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_33450 helD; DNA 3'-5' helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B657_36310 ssbB; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E B657_40900 ssbA; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E B657_27480 recD; Exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E B657_16940 recA; Multifunctional SOS repair factor K03553 recA; recombination protein RecA
E B657_27740 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E B657_27730 ruvB; Holliday junction DNA helicase, ATP-dependentcomponent K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E B657_15710 priA; Primosomal replication factor Y (primosomal protein N') K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E B657_10650 sbcC; DNA ATP-dependent repair enzyme K03546 sbcC; DNA repair protein SbcC/Rad50
E B657_10640 sbcD; DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E B657_16940 recA; Multifunctional SOS repair factor K03553 recA; recombination protein RecA
E B657_00870 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E B657_00040 recF; DNA repair and genetic recombination factor K03629 recF; DNA replication and repair protein RecF
E B657_15870 recG; Branch migrating ATP-dependent DNA helicaseinvolved K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E B657_27620 recJ; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E B657_20350 yorK; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E B657_25280 recO; DNA double strand break repair and homologous recombination K03584 recO; DNA repair protein RecO (recombination protein O)
E B657_00210 recR; DNA repair and recombination protein K06187 recR; recombination protein RecR
E B657_24240 recN; Factor for double strand breaks DNA repair andgenetic K03631 recN; DNA repair protein RecN (Recombination protein N)
E B657_22310 recU; Holliday junction resolvase K03700 recU; recombination protein U
E B657_27740 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E B657_27730 ruvB; Holliday junction DNA helicase, ATP-dependentcomponent K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E B657_10630 addA; ATP-dependent deoxyribonuclease (subunit A) K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E B657_10620 addB; ATP-dependent deoxyribonuclease (subunit B) K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E B657_10650 sbcC; DNA ATP-dependent repair enzyme K03546 sbcC; DNA repair protein SbcC/Rad50
E B657_10640 sbcD; DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E B657_13410 ykoV; ATP-dependent DNA ligase subunit K10979 ku; DNA end-binding protein Ku
E B657_13400 ykoU; ATP-dependent DNA ligase subunit K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F B657_00070 gyrA; DNA gyrase (subunit A) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F B657_00060 gyrB; DNA gyrase (subunit B) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F B657_16120 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F B657_21050 yonN; Putative HU-related DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F B657_22790 hbs; Non-specific DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F B657_27620 recJ; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F B657_20350 yorK; Putative single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F B657_25280 recO; DNA double strand break repair and homologous recombination K03584 recO; DNA repair protein RecO (recombination protein O)
F B657_00210 recR; DNA repair and recombination protein K06187 recR; recombination protein RecR
F B657_06620 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F B657_19220 yocI; Putative ATP-dependent nucleic acid helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F B657_23020 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F B657_35160 uvrA; Excinuclease ABC (subunit A) K03701 uvrA; excinuclease ABC subunit A
F B657_35170 uvrB; Excinuclease ABC (subunit B) K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D B657_23710 polYB; Y family DNA polymerase V bypassing lesions duringreplication K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D B657_23870 polYA; DNA-damage lesion bypass DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D B657_18930 yobH; Putative DNA repair protein K03502 umuC; DNA polymerase V
D B657_21500 uvrX; Lesion bypass phage DNA polymerase K03502 umuC; DNA polymerase V
C Other SOS response factors
D B657_16940 recA; Multifunctional SOS repair factor K03553 recA; recombination protein RecA
D B657_17850 lexA; Transcriptional repressor of the SOS regulon K01356 lexA; repressor LexA [EC:3.4.21.88]
D B657_24240 recN; Factor for double strand breaks DNA repair andgenetic K03631 recN; DNA repair protein RecN (Recombination protein N)
D B657_36310 ssbB; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D B657_40900 ssbA; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D B657_08520 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D B657_28590 polX; DNA polymerase X K02347 polX; DNA polymerase (family X)
C DNA helicases
D B657_22150 ypvA; Putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D B657_22400 dinG; Damage inducible ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D B657_34780 yvcI; Putative triphosphate pyrophosphate hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_30630 ytkD; Nucleoside triphosphate phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_04330 mutT; Putative NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B657_20020 yosS; SPbeta phage deoxyuridine 5'-triphosphatenucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D B657_17660 yncF; Deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D B657_17380 nrdE; Ribonucleoside-diphosphate reductase (majorsubunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D B657_17390 nrdF; Ribonucleoside-diphosphate reductase (minorsubunit) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D B657_29250 nrnA; Oligoribonuclease (nanoRNAse), 3',5'-bisphosphatenucleotidase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024