+F Repair protein KO
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DNA Repair and Recombination Proteins - Bacillus thuringiensis MC28
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MC28_1249 Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MC28_2313 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MC28_4631 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MC28_0142 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MC28_5247 a/g-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MC28_0781 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MC28_1005 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2236 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_0181 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2257 Phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_4390 Mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_5347 MutT/NUDIX K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G381 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G388 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_4075 8-oxo-dGTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_5266 Mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2692 MutT/Nudix K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G226 Deoxyuridine 5'-triphosphate nucleotidohydrolase, DUTP K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MC28_1249 Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MC28_2906 Methylphosphotriester-DNA alkyltransferase K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D MC28_2907 methylated-DNA--protein-cysteine methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MC28_2313 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MC28_4631 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MC28_0763 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MC28_2908 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MC28_5150 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MC28_0142 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MC28_5247 a/g-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MC28_3864 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MC28_0781 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MC28_2905 Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MC28_3576 nfo; endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E MC28_3701 Exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MC28_5021 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MC28_3865 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MC28_4401 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MC28_4402 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E MC28_3798 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E MC28_0449 ATP-dependent DNA helicase, UvrD/REP K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_0274 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_2003 UvrD/Rep helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_5020 ATP-dependent DNA helicase pcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_3865 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MC28_5021 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MC28_4814 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MC28_4815 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MC28_4849 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MC28_4575 rpoE; DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F MC28_3093 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MC28_4768 Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MC28_2938 mutS; DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
E MC28_3832 mutS2; recombination and DNA strand exchange inhibitor protein K07456 mutS2; DNA mismatch repair protein MutS2
E MC28_2634 DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MC28_2937 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MC28_3472 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MC28_3471 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MC28_3882 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MC28_3041 polC; DNA polymerase III polC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MC28_1884 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MC28_4722 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MC28_3614 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MC28_4746 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MC28_2759 DNA polymerase III alpha subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MC28_4738 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MC28_5021 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MC28_0449 ATP-dependent DNA helicase, UvrD/REP K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_0274 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_2003 UvrD/Rep helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_5020 ATP-dependent DNA helicase pcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MC28_4705 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MC28_3685 Helicase, RecD/TraA K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MC28_3713 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E MC28_3712 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MC28_3091 primosomal protein N` K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MC28_1568 Exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E MC28_1567 Nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MC28_4795 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MC28_4724 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E MC28_3078 ATP-dependent DNA helicase recG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MC28_3701 Exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MC28_3589 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E MC28_4740 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MC28_3466 DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MC28_0784 recU; Holliday junction resolvase recU K03700 recU; recombination protein U
E MC28_G223 Recombination protein U K03700 recU; recombination protein U
E MC28_B61 penicillin-binding protein K03700 recU; recombination protein U
E MC28_3713 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E MC28_3712 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E MC28_0358 addA; DNA helicase/exodeoxyribonuclease V, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MC28_0357 addB; ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MC28_1568 Exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E MC28_1567 Nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MC28_4726 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MC28_4725 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MC28_3056 DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F MC28_E171 DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F MC28_F289 DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MC28_0744 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F MC28_1583 DNA-binding protein HU 1 K03530 hupB; DNA-binding protein HU-beta
F MC28_2892 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F MC28_F097 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F MC28_C056 small DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F MC28_G154 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MC28_1499 DNA-binding phage-related protein K07455 recT; recombination protein RecT
F MC28_3701 Exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MC28_3589 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F MC28_4740 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MC28_5021 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MC28_0719 ATP-dependent DNA helicase Q K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MC28_2005 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MC28_4401 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MC28_4402 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MC28_3437 dinB; Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MC28_2293 DNA-damage repair protein K03502 umuC; DNA polymerase V
D MC28_2976 DNA-damage repair protein K03502 umuC; DNA polymerase V
D MC28_D068 DNA-damage repair protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D MC28_2835 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MC28_G330 Helix-turn-helix domain protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D MC28_3466 DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MC28_4705 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MC28_5242 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D MC28_3833 PHP domain protein K02347 polX; DNA polymerase (family X)
C DNA helicases
D MC28_0776 DnaQ family exonuclease/DinG family helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MC28_1005 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2236 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_0181 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2257 Phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_4390 Mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_5347 MutT/NUDIX K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G381 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G388 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_4075 8-oxo-dGTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_5266 Mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_2692 MutT/Nudix K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MC28_G226 Deoxyuridine 5'-triphosphate nucleotidohydrolase, DUTP K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MC28_0584 Ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MC28_3885 Phosphoesterase, DHH K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024