+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Burkholderia sp. HB1</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      AC233_25415 DNA methylase N-4	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] 
D      AC233_04375 cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
D      AC233_32095 damage-inducible protein	K07473 dinJ; DNA-damage-inducible protein J 
C    YoeB-YefM
D      AC233_30205 toxin YoeB	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      AC233_30200 prevent-host-death protein	K19159 yefM; antitoxin YefM 
C    HipA-HipB
D      AC233_30545 toxin HipA	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      AC233_07960 toxin HipA	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      AC233_30550 XRE family transcriptional regulator	K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
D      AC233_13975 plasmid maintenance protein CcdB	K19163 ccdB; toxin CcdB 
D      AC233_13970 post-segregation antitoxin CcdA	K19164 ccdA; antitoxin CcdA 
C    ParE-ParD
D      AC233_00365 hypothetical protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      AC233_32100 RelE/StbE family addiction module toxin	K19092 parE1_3_4; toxin ParE1/3/4 
D      AC233_04715 CopG family transcriptional regulator	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
D      AC233_03965 death-on-curing protein	K07341 doc; death on curing protein 
C    HigB-HigA
D      AC233_13810 plasmid maintenance system killer	K07334 higB-1; toxin HigB-1 
D      AC233_06970 transcriptional regulator	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      AC233_13815 XRE family transcriptional regulator	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
C    VapC-VapB
D      AC233_14585 twitching motilty protein PilT	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      AC233_14590 AbrB family transcriptional regulator	K18829 mvpT; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      AC233_31860 plasmid stabilization protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      AC233_31855 plasmid stabilization protein	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      AC233_15765 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      AC233_00570 rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      AC233_21090 rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      AC233_04440 DNA topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      AC233_04435 DNA topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      AC233_10115 glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      AC233_25630 hypothetical protein	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    AC233_11740 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023