+D	AMR gene	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Antimicrobial Resistance Genes - Caballeronia sp. NK8</h2>
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A<b>Gene variants</b>
B  beta-Lactamase genes
C    Class A [MT]
C    Class D [MT]
C    Class C [MT]
C    Class B [MT]
B  Aminoglycoside resistance genes
C    N-Acetyltransferases
C    Other acetyltransferases
C    O-Nucleotidyltransferases
C    O-Phosphotransferases
C    16S rRNA methyltransferases
B  Tetracycline resistance genes
C    Transporters
C    Others
B  Macrolide resistance genes
C    23S rRNA methyltransferases
C    Transporters
C    Others
D      NK8_51570 acetyltransferase	K18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-] 
B  Phenicol resistance genes
C    Transporters
C    Acetyltransferases
C    Phosphotransferase
C    23S rRNA methyltransferase
B  Sulfonamide resistance genes
C    Dihydropteroate synthase
B  Trimethoprim resistance genes
C    Dihydrofolate reductases
B  Quinolone resistance genes
C    Transporter
C    Other
B  Rifamycin resistance genes
C    ADP-ribosyl transferases
C    Oxygenases
B  Fosfomycin resistance genes
C    Transferases
C    Others
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A<b>Gene sets</b>
B  beta-Lactam resistance modules
C    Methicillin resistance [MD:M00625]
C    beta-Lactam resistance, Bla system [MD:M00627]
C    Imipenem resistance, repression of porin OprD [MD:M00745]
D      NK8_30260 heavy metal sensor histidine kinase	K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] 
D      NK8_34050 heavy metal sensor histidine kinase	K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] 
D      NK8_44730 heavy metal sensor histidine kinase	K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] 
D      NK8_53950 heavy metal sensor histidine kinase	K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] 
D      NK8_30270 heavy metal response regulator transcription factor	K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 
D      NK8_34060 heavy metal response regulator transcription factor	K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 
D      NK8_44720 heavy metal response regulator transcription factor	K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 
D      NK8_53940 irlR; heavy metal response regulator transcription factor IrlR	K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 
B  Vancomycin resistance modules
C    Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D      NK8_11800 ddpX; D-alanyl-D-alanine dipeptidase	K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] 
C    Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D      B  Tetracycline resistance
C    Tetracycline resistance, efflux pump Tet38 [MD:M00704]
B  CAMP resistance modules
C    Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
C    Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
D      NK8_35380 mprF; bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] 
C    Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C    Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
B  Multipdrug resistance modules
C    Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
D      NK8_05540 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_05570 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_14980 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_34080 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_44780 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_54540 efflux RND transporter periplasmic adaptor subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      NK8_05550 efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_05580 efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_14990 efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_34090 efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_44790 efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_54530 multidrug efflux RND transporter permease subunit	K18138 acrB; multidrug efflux pump 
D      NK8_05560 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_05590 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_10540 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_16850 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_28210 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_36790 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_44770 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_54520 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_65580 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_68700 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
C    Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
D      NK8_50590 efflux RND transporter periplasmic adaptor subunit	K18298 mexE; membrane fusion protein, multidrug efflux system 
D      NK8_50600 efflux RND transporter permease subunit	K18299 mexF; multidrug efflux pump 
D      NK8_50610 efflux transporter outer membrane subunit	K18300 oprN; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
D      NK8_39530 efflux RND transporter periplasmic adaptor subunit	K18302 mexJ; membrane fusion protein, multidrug efflux system 
D      NK8_39540 efflux RND transporter permease subunit	K18303 mexK; multidrug efflux pump 
D      NK8_05560 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_05590 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_10540 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_16850 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_28210 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_36790 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_44770 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_54520 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_65580 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_68700 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
D      NK8_05560 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_05590 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_10540 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_16850 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_28210 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_36790 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_44770 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_54520 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_65580 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
D      NK8_68700 efflux transporter outer membrane subunit	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
D      NK8_17270 cueR; Cu(I)-responsive transcriptional regulator	K19591 cueR; MerR family transcriptional regulator, copper efflux regulator 
C    Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
D      NK8_68730 HAMP domain-containing protein	K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3] 
D      NK8_84290 HAMP domain-containing protein	K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3] 
D      NK8_68720 response regulator transcription factor	K18144 adeR; two-component system, OmpR family, response regulator AdeR 
D      NK8_84270 response regulator transcription factor	K18144 adeR; two-component system, OmpR family, response regulator AdeR 
D      NK8_68680 efflux RND transporter periplasmic adaptor subunit	K18145 adeA; membrane fusion protein, multidrug efflux system 
D      NK8_84230 efflux RND transporter periplasmic adaptor subunit	K18145 adeA; membrane fusion protein, multidrug efflux system 
D      NK8_68690 multidrug efflux RND transporter permease subunit	K18146 adeB; multidrug efflux pump 
D      NK8_84240 multidrug efflux RND transporter permease subunit	K18146 adeB; multidrug efflux pump 
C    Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
D      NK8_15490 TolC family outer membrane protein	K12340 tolC; outer membrane protein 
D      NK8_40910 hypothetical protein	K12340 tolC; outer membrane protein 
D      NK8_64890 TolC family protein	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
D      NK8_15490 TolC family outer membrane protein	K12340 tolC; outer membrane protein 
D      NK8_40910 hypothetical protein	K12340 tolC; outer membrane protein 
D      NK8_64890 TolC family protein	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
D      NK8_21570 LysR family transcriptional regulator	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
D      NK8_32760 LysR family transcriptional regulator	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
D      NK8_38020 LysR family transcriptional regulator	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
D      NK8_76680 LysR family transcriptional regulator	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
D      NK8_38000 efflux RND transporter periplasmic adaptor subunit	K18901 bpeE; membrane fusion protein, multidrug efflux system 
D      NK8_37990 multidrug efflux RND transporter permease subunit	K18902 bpeF; multidrug efflux pump 
D      NK8_34070 efflux transporter outer membrane subunit	K18903 oprC; outer membrane protein, multidrug efflux system 
D      NK8_37980 efflux transporter outer membrane subunit	K18903 oprC; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump AbcA [MD:M00700]
C    Multidrug resistance, efflux pump NorB [MD:M00702]
C    Multidrug resistance, efflux pump QacA [MD:M00714]
C    Multidrug resistance, efflux pump MepA [MD:M00705]
C    Multidrug resistance, repression of porin OmpF [MD:M00746]
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#Last updated: December 28, 2017