+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Clostridium acetobutylicum ATCC 824</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
C    Surveillance factors
D      Surveillance complex
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        CA_C1256 Ribonucleases G/E family protein	K08301 rng; ribonuclease G [EC:3.1.26.-] 
E        CA_C1748 rncS; DsRNA-specific ribonuclease III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        CA_C1683 Predicted metal-dependent hydrolase of metallo-beta-lactamase superfamily	K12574 rnj; ribonuclease J [EC:3.1.-.-] 
E        CA_C1816 HD superfamily hydrolase, YMDA B.subtilis ortholog	K18682 rny; ribonucrease Y [EC:3.1.-.-] 
E        CA_C0715 vacB; FUSION ribonuclease and ribosomal protein S1 domain	K12573 rnr; ribonuclease R [EC:3.1.13.1] 
E        CA_C0749 HD hydrolase superfamily protein	K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] 
E        CA_C2261 HD-hydrolase domain containing protein, YHAM B.subtilis ortholog	K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] 
D      Helicases
E        CA_C0784 ATP-dependent RNA helicase, superfamily II	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CA_C2748 deaD; ATP dependent RNA helicase DeaD, superfamily II	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CA_C3010 ATP-dependent RNA helicase (superfamily II), YDBR B.subtilis ortholog	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CA_C2687 recQ; RecQ protein, superfamily II DNA helicase	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] 
D      Other RNA degradosome components
E        CA_C0713 eno; Enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        CA_C1808 pnpA; Polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        CA_C2889 rho; Transcription termination factor rho	K03628 rho; transcription termination factor Rho 
E        CA_C0517 pfk; 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        CA_C1282 dnaK; Molecular chaperone DnaK, HSP70 family	K04043 dnaK; molecular chaperone DnaK 
E        CA_C2703 groEL; Chaperonin GroEL, HSP60 family	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        CA_C1834 Host factor I protein Hfq	K03666 hfq; host factor-I protein 
D      Others
E        CA_C0622 Polyphosphate kinase	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] 
E        CA_C0311 PolyA polymerase	K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] 
E        CA_C2209 csrA; Carbon storage regulator, csrA	K03563 csrA; carbon storage regulator 
E        CA_C0511 Predicted P-loop containing kinase, similar to B.subtilis yvcJ	K06958 rapZ; RNase adapter protein RapZ 
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
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#Last updated: August 27, 2025