+F Repair protein KO
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DNA Repair and Recombination Proteins - Candida albicans
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CAALFM_C407010CA CaO19.3108; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CAALFM_C306400CA CaO19.7425; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CAALFM_C306530WA CaO19.7442; hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E CAALFM_C703910WA OGG1; 8-oxoguanine glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CAALFM_C108200WA NTG1; bifunctional N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CAALFM_C306430WA APN1; DNA-(apurinic or apyrimidinic site) lyase K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E CAALFM_C110650WA APN2; DNA-(apurinic or apyrimidinic site) lyase K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F CAALFM_C702790CA POL3; DNA-directed DNA polymerase delta K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F CAALFM_C504740CA HYS2; DNA-directed DNA polymerase delta subunit K02328 POLD2; DNA polymerase delta subunit 2
F CAALFM_C105850WA POL32; DNA polymerase delta subunit K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F CAALFM_CR07000CA POL2; DNA polymerase epsilon catalytic subunit K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F CAALFM_CR09900CA DPB2; DNA polymerase epsilon noncatalytic subunit K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F CAALFM_C200430CA DPB4; DNA polymerase epsilon noncatalytic subunit K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F CAALFM_C103640CA HFL1; DNA polymerase epsilon noncatalytic subunit K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E CAALFM_C401770WA POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E CAALFM_CR04560CA CaO19.547; multifunctional nuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E CAALFM_C300830CA CaO19.6155; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E CAALFM_CR03440WA CaO19.2376; hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CAALFM_CR03590CA CaO19.4383; DNA 5'-adenosine monophosphate hydrolase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F CAALFM_C307660WA CaO19.6722; hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CAALFM_C201850WA RAD23; Rad23p K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F CAALFM_C302450WA HRT1; SCF ubiquitin ligase complex subunit K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CAALFM_C106040WA RTT101; cullin K10609 CUL4; cullin 4
E NER4 complex
F CAALFM_C201840CA RAD7; UV-damaged DNA-binding protein K15082 RAD7; DNA repair protein RAD7
F CAALFM_C102810WA RAD16; DNA repair protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F CAALFM_CR10680WA RPO21; DNA-directed RNA polymerase II core subunit K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F CAALFM_C101590CA CaO19.3349; DNA-directed RNA polymerase II core subunit K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F CAALFM_C405630WA CaO19.1248; DNA-directed RNA polymerase II core subunit K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F CAALFM_C204650CA RPB4; DNA-directed RNA polymerase II subunit K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F CAALFM_C112820CA CaO19.6340; DNA-directed RNA polymerase core subunit K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F CAALFM_C503360WA RPO26; DNA-directed RNA polymerase core subunit K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F CAALFM_C101570CA RPB7; DNA-directed RNA polymerase II subunit K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F CAALFM_CR04780WA RPB8; DNA-directed RNA polymerase core subunit K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F CAALFM_C207200WA CaO19.2276; DNA-directed RNA polymerase II core subunit K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F CAALFM_C403040WA DNA-directed RNA polymerase core subunit K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F CAALFM_C100940WA RPB11; DNA-directed RNA polymerase II core subunit K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F CAALFM_C114390WA RPC10; DNA-directed RNA polymerase core subunit K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F CAALFM_C302450WA HRT1; SCF ubiquitin ligase complex subunit K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CAALFM_C106040WA RTT101; cullin K10609 CUL4; cullin 4
F CAALFM_C302770CA CaO19.268; hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F CAALFM_CR07910CA CaO19.607; DNA-dependent ATPase K10841 ERCC6; DNA excision repair protein ERCC-6
F CAALFM_CR05910WA CaO19.6623; hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E CAALFM_CR02970CA CaO19.2857; TFIIH/NER complex ATPase/helicase subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E CAALFM_C700050CA RAD3; TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E CAALFM_C404120CA CaO19.5297; TFIIH/NER complex subunit K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E CAALFM_C201490CA CaO19.1457; TFIIH/NER complex subunit K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E CAALFM_C600640CA CaO19.4194; TFIIH/NER complex subunit K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E CAALFM_CR05560WA CaO19.5846; TFIIH/NER complex subunit K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E CAALFM_C107280CA TFIIH complex subunit K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E CAALFM_C106710WA CaO19.6239; TFIIH complex serine/threonine-protein kinase subunit K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E CAALFM_C101820CA CaO19.4542; TFIIH complex kinase subunit K06634 CCNH; cyclin H
E CAALFM_C500690CA TFB3; TFIIH/NER complex subunit K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E CAALFM_C200380CA RFA1; replication factor A subunit protein K07466 RFA1; replication factor A1
E CAALFM_C207120WA RFA2; Rfa2p K10739 RFA2; replication factor A2
E CAALFM_C109670CA CaO19.4830; hypothetical protein K10740 RPA3; replication factor A3
D Other NER factors
E CAALFM_C702020WA RAD14; Rad14p K10847 XPA; DNA-repair protein complementing XP-A cells
E CAALFM_C105820CA RAD10; Rad10p K10849 ERCC1; DNA excision repair protein ERCC-1
E CAALFM_C210440CA RAD1; ssDNA endodeoxyribonuclease K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E CAALFM_C403550WA RAD2; ssDNA endodeoxyribonuclease K10846 ERCC5; DNA excision repair protein ERCC-5
E CAALFM_C300830CA CaO19.6155; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CAALFM_C301450CA MET18; Met18p K15075 MET18; DNA repair/transcription protein MET18/MMS19
E CAALFM_CR00370WA CaO19.7497; cullin K03869 CUL3; cullin 3
E CAALFM_C104550WA ELC1; elongin C K03872 ELOC; elongin-C
E CAALFM_C103810CA ELA1; elongin A K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CAALFM_C407120CA MSH2; mismatch repair ATPase K08735 MSH2; DNA mismatch repair protein MSH2
E CAALFM_C208680WA MSH3; mismatch repair protein K08736 MSH3; DNA mismatch repair protein MSH3
E CAALFM_C113170CA MSH6; mismatch repair ATPase K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E CAALFM_C400790CA MLH1; mismatch repair ATPase K08734 MLH1; DNA mismatch repair protein MLH1
E CAALFM_C209470CA PMS1; ATP-binding mismatch repair protein K10858 PMS2; DNA mismatch repair protein PMS2
E CAALFM_C114400CA MLH3; mismatch repair protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E CAALFM_C702790CA POL3; DNA-directed DNA polymerase delta K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E CAALFM_C504740CA HYS2; DNA-directed DNA polymerase delta subunit K02328 POLD2; DNA polymerase delta subunit 2
E CAALFM_C105850WA POL32; DNA polymerase delta subunit K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E CAALFM_C200380CA RFA1; replication factor A subunit protein K07466 RFA1; replication factor A1
E CAALFM_C207120WA RFA2; Rfa2p K10739 RFA2; replication factor A2
E CAALFM_C109670CA CaO19.4830; hypothetical protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E CAALFM_C205790CA RFC1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E CAALFM_CR10700WA RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E CAALFM_C700820WA RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E CAALFM_C200950CA RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E CAALFM_C504000WA RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E CAALFM_C401770WA POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E CAALFM_C500630CA EXO1; Rad2 family nuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E CAALFM_C300830CA CaO19.6155; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CAALFM_C701270CA CaO19.6907; hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E CAALFM_C701340WA MRE11; MRX complex nuclease subunit K10865 MRE11; double-strand break repair protein MRE11
E CAALFM_C302000WA RAD50; MRX complex DNA-binding subunit K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E CAALFM_C701340WA MRE11; MRX complex nuclease subunit K10865 MRE11; double-strand break repair protein MRE11
E CAALFM_C302000WA RAD50; MRX complex DNA-binding subunit K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E CAALFM_CR02200CA RAD51; recombinase K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E CAALFM_CR02200CA RAD51; recombinase K04482 RAD51; DNA repair protein RAD51
E CAALFM_C208110WA RAD57; putative DNA-dependent ATPase K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E CAALFM_C600510CA RAD52; recombinase K10873 RAD52; DNA repair and recombination protein RAD52
E CAALFM_C405270CA RAD59; Rad59p K10959 RAD59; DNA repair protein RAD59
D Rad54 family proteins
E CAALFM_C113660WA RAD54; DNA-dependent ATPase K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E CAALFM_C210840WA RDH54; DNA-dependent ATPase K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E CAALFM_C210570WA SGS1; ATP-dependent DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E CAALFM_C210570WA SGS1; ATP-dependent DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CAALFM_C304740CA CaO19.5934; DNA topoisomerase 3 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CAALFM_C210450WA NCE4; Nce4p K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E CAALFM_C200380CA RFA1; replication factor A subunit protein K07466 RFA1; replication factor A1
E CAALFM_C207120WA RFA2; Rfa2p K10739 RFA2; replication factor A2
E CAALFM_C109670CA CaO19.4830; hypothetical protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E CAALFM_CR03800CA PPH3; phosphoprotein phosphatase PP4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E CAALFM_C102280CA PSY2; Psy2p K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E CAALFM_CR03100WA SMC5; DNA repair ATPase K22803 SMC5; structural maintenance of chromosomes protein 5
E CAALFM_C701580WA SMC6; DNA repair protein K22804 SMC6; structural maintenance of chromosomes protein 6
E CAALFM_C504790CA CaO19.3965; hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E CAALFM_C306200CA MMS21; SUMO ligase K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E CAALFM_C403170WA CaO19.2673; Smc5-Smc6 complex subunit K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E CAALFM_C400800WA CaO19.4161; Smc5-Smc6 complex subunit K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E CAALFM_C600770CA CaO19.3648; hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E CAALFM_C600540WA CaO19.4206; hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E CAALFM_C406880CA proteasome regulatory particle lid subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E CAALFM_C107980CA CaO19.5069; hypothetical protein K10991 SWI5; DNA repair protein Swi5/Sae3
E CAALFM_CR05580CA CaO19.5844; hypothetical protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E CAALFM_C500230CA CaO19.972; endonuclease K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E CAALFM_C402590CA CaO19.2740; hypothetical protein K15079 SLX4; structure-specific endonuclease subunit SLX4
E CAALFM_CR05010WA CaO19.652; crossover junction endodeoxyribonuclease K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CAALFM_C208280WA EAF3; Eaf3p K11339 MORF4L1; mortality factor 4-like protein 1
E CAALFM_CR09860WA YTA6; putative AAA family ATPase K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E CAALFM_C302970CA CaO19.291; metalloendopeptidase K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E CAALFM_C406190CA MPH1; 3'-5' DNA helicase K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
E CAALFM_CR00390WA MMS22; Mms22p K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E CAALFM_C111810WA CAS1; ATP-dependent DNA helicase K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E CAALFM_CR03390CA YKU80; ATP-dependent DNA helicase K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E CAALFM_C701340WA MRE11; MRX complex nuclease subunit K10865 MRE11; double-strand break repair protein MRE11
E CAALFM_C302000WA RAD50; MRX complex DNA-binding subunit K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E CAALFM_C203030WA LIG4; DNA ligase (ATP) K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
D Other NHEJ factors
E CAALFM_CR03440WA CaO19.2376; hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CAALFM_CR03590CA CaO19.4383; DNA 5'-adenosine monophosphate hydrolase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CAALFM_C210780CA PSO2; Pso2p K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E CAALFM_C112840WA CaO19.4914; hypothetical protein K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E CAALFM_C210570WA SGS1; ATP-dependent DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CAALFM_C304740CA CaO19.5934; DNA topoisomerase 3 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CAALFM_C210450WA NCE4; Nce4p K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E CAALFM_CR02200CA RAD51; recombinase K04482 RAD51; DNA repair protein RAD51
E CAALFM_C700210CA CaO19.7101; hypothetical protein K11137 TELO2; telomere length regulation protein
E CAALFM_C112830CA CaO19.4913; hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E CAALFM_C701270CA CaO19.6907; hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CAALFM_C203540WA RAD32; DNA-directed DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D CAALFM_C406020CA CaO19.4412; deoxycytidyl transferase K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D CAALFM_C306080WA REV3; Rev3p K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D CAALFM_C209480WA CaO19.1406; hypothetical protein K03508 POLZ2; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D CAALFM_C703870WA RAD6; E2 ubiquitin-conjugating protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D CAALFM_C601770WA RAD18; E3 ubiquitin-protein ligase K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CAALFM_C200350WA CaO19.2097; DNA helicase K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D CAALFM_C112650CA CaO19.6358; E2 ubiquitin-conjugating protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D CAALFM_C500560WA CaO19.2225; E2 ubiquitin-conjugating protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D CAALFM_C401770WA POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
D CAALFM_C400030CA CaO19.366; hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D CAALFM_C402700WA CaO19.2728; hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D CAALFM_CR10700WA RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D CAALFM_C700820WA RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D CAALFM_C200950CA RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D CAALFM_C504000WA RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D CAALFM_C400030CA CaO19.366; hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D CAALFM_C206220CA MEC3; Mec3p K02544 MEC3; G2-specific checkpoint protein
D CAALFM_C302560WA DDC1; Ddc1p K06663 DDC1; DNA damage checkpoint protein
C FPC (fork protection complex)
D CAALFM_C501460WA YBL053; Ybl053p K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D CAALFM_C206130WA CSM3; Csm3p K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D CAALFM_C111440CA GIN1; chromatin-modulating protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D CAALFM_C700210CA CaO19.7101; hypothetical protein K11137 TELO2; telomere length regulation protein
D CAALFM_C103630WA CaO19.3062; hypothetical protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D CAALFM_C502210WA CaO19.4228; hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D CAALFM_C603010WA TEL1; DNA-binding protein kinase K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D CAALFM_C505100CA DUN1; serine/threonine protein kinase K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D CAALFM_C300800WA MIH1; putative tyrosine protein phosphatase K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D CAALFM_C103220CA BMH1; 14-3-3 family protein K06630 YWHAE; 14-3-3 protein epsilon
D CAALFM_C303810WA RAD53; serine/threonine/tyrosine protein kinase K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D CAALFM_C502610CA RAD9; chromatin-binding protein K06661 RAD9; DNA repair protein RAD9
D CAALFM_C504060CA MEC1; protein kinase K02543 MEC1; cell cycle checkpoint protein MEC1
D CAALFM_C201950CA AMN1; Amn1p K15081 AMN1; antagonist of mitotic exit network protein 1
D CAALFM_C110010CA SWE1; tyrosine protein kinase K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D CAALFM_C300670CA FKH2; forkhead family transcription factor K24664 FKH; forkhead protein FKH
D CAALFM_C503090WA VPS4; AAA family ATPase K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D CAALFM_C603120WA POL5; DNA-directed DNA polymerase K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D CAALFM_C102390WA CaO19.2926; hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D CAALFM_CR03490WA DEM1; Dem1p K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
C PSO4 complex
D CAALFM_C307480WA CaO19.6740; E3 ubiquitin-protein ligase K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D CAALFM_C109370WA CEF1; Cef1p K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D CAALFM_C300500CA CaO19.5413; mRNA splicing protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D CAALFM_C104150CA CaO19.1049; hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CAALFM_C101330CA DUT1; bifunctional dITP/dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CAALFM_C203160CA RNR1; ribonucleotide-diphosphate reductase subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D CAALFM_CR05570CA RNR3; Rnr3p K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D CAALFM_C203010CA RNR21; ribonucleotide-diphosphate reductase subunit K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D CAALFM_C207570WA RNR22; Rnr22p K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CAALFM_C407010CA CaO19.3108; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CAALFM_C306400CA CaO19.7425; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CAALFM_C208420WA CaO19.3639; hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CAALFM_C601820CA FPG1; Fpg1p K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CAALFM_C108200WA NTG1; bifunctional N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CAALFM_C305010CA CaO19.5970; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E CAALFM_C305010CA CaO19.5970; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CAALFM_C104150CA CaO19.1049; hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CAALFM_C101330CA DUT1; bifunctional dITP/dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024