+D Protein KO
#
Membrane Trafficking - Candida albicans
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
D CAALFM_C104210CA CDC3; septin K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D CAALFM_C112410CA PKH2; serine/threonine protein kinase K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
D CAALFM_C600350WA PKH3; protein kinase K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D CAALFM_C703710CA PLC1; phosphatidylinositol phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D CAALFM_C111590WA PLD1; phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D CAALFM_C301160WA MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D CAALFM_C502340CA CST20; mitogen-activated protein kinase kinase kinase kinase K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D CAALFM_C602160WA CaO19.3456; hypothetical protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D CAALFM_C502890WA YNK1; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D CAALFM_CR00260WA KIN2; serine/threonine protein kinase K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D CAALFM_C108680CA CaO19.4726; frequenin K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D CAALFM_CR01750CA SEC4; Rab family GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D CAALFM_C406030WA CMD1; calmodulin K02183 CALM; calmodulin
D CAALFM_C503370CA CaO19.2642; hypothetical protein K02183 CALM; calmodulin
D CAALFM_C112970CA SEC2; guanine nucleotide exchange factor K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D CAALFM_C702320WA SEC1; Sec1p K15292 STXBP1; syntaxin-binding protein 1
D CAALFM_C600410CA SRO77; putative Rab GTPase-binding protein K08518 STXBP5; syntaxin-binding protein 5
D CAALFM_CR07470WA CaO19.6118; guanine nucleotide exchange factor K19952 RABIF; guanine nucleotide exchange factor
D CAALFM_C500760WA CaO19.578; Rab GTPase-activating protein K19953 GRTP1; TBC1 domain family member 6
D CAALFM_C405600WA GYP2; Gyp2p K19951 TBC1D8_9; TBC1 domain family member 8/9
D CAALFM_C400150CA PEX5; Pex5p K13342 PEX5; peroxin-5
D CAALFM_C307170CA CaO19.6783; GTPase-activating protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D CAALFM_C104070CA BET4; Rab geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D CAALFM_CR09890CA BET2; Rab geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D CAALFM_C300630WA CaO19.5395; hypothetical protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D CAALFM_C108450CA CDC42; Rho family GTPase K04393 CDC42; cell division control protein 42
D CAALFM_C106730WA RAC1; Rho family GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D CAALFM_C406250CA SEC3; GTP-Rho binding exocyst subunit K19983 EXOC1; exocyst complex component 1
D CAALFM_C604170CA SEC5; exocyst subunit K17637 EXOC2; exocyst complex component 2
D CAALFM_C300110CA SEC6; SNARE-binding exocyst subunit K06110 EXOC3; exocyst complex component 3
D CAALFM_C600780WA SEC8; exocyst subunit K06111 EXOC4; exocyst complex component 4
D CAALFM_C407190WA SEC10; exocyst subunit K19984 EXOC5; exocyst complex component 5
D CAALFM_C404290WA SEC15; Rab GTPase-binding exocyst subunit K19985 EXOC6; exocyst complex component 6
D CAALFM_C702050CA EXO70; GTP-Rho binding exocyst subunit K07195 EXOC7; exocyst complex component 7
D CAALFM_C601280WA EXO84; exocyst subunit K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D CAALFM_C406880CA proteasome regulatory particle lid subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
D CAALFM_CR08460WA TPM2; tropomyosin K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D CAALFM_C204140WA CHS5; Chs5p K19877 CHS5; chitin biosynthesis protein CHS5
D CAALFM_C703060CA CHS6; Chs6p K19880 CHS6; Chs5-Arf1p-binding protein CHS6/BCH2
D CAALFM_C503820CA BUD7; exomer complex subunit K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D CAALFM_C112160WA MSO1; Mso1p K19992 MSO1; protein MSO1
D CAALFM_C400350WA PEP7; Pep7p K12481 RBSN; rabenosyn-5
D CAALFM_C110270CA SFH5; Sfh5p K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D CAALFM_C209740WA SSO2; syntaxin K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
D CAALFM_C304320WA VAM3; SNAP receptor K21155 VAM3; syntaxin VAM3
C Stx-TGN / EE
D CAALFM_C202210CA TLG2; Tlg2p K08489 STX16; syntaxin 16
C Stx-cisGolgi
D CAALFM_C100660CA CaO19.6039; t-SNARE syntaxin K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
D CAALFM_C704270CA UFE1; Ufe1p K08492 STX18; syntaxin 18
B SNAP-25[N] (Qb)
C Vti1
D CAALFM_C303400CA VTI1; v-SNARE protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D CAALFM_C701740CA CaO19.6551; hypothetical protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D CAALFM_C102510WA CaO19.2940; hypothetical protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
D CAALFM_C602570CA SEC20; Sec20p K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
D CAALFM_C504150CA CaO19.3898; hypothetical protein K08499 TLG1; member of the syntaxin family of t-SNAREs
C STX8
D CAALFM_CR03140CA SYN8; syntaxin K08501 STX8; syntaxin 8
D CAALFM_C600240CA CaO19.1182; hypothetical protein K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D CAALFM_C209680WA CaO19.1386; hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
D CAALFM_CR01190CA SFT1; Sft1p K08505 SFT1; protein transport protein SFT1
C Syp7
C Use1
D CAALFM_C602680WA CaO19.5539; SNAP receptor K08507 USE1; unconventional SNARE in the endoplasmic reticulum protein 1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D CAALFM_C601100WA SEC9; Sec9p K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D CAALFM_C113690CA SNAP receptor K08513 VAMP4; vesicle-associated membrane protein 4
D CAALFM_C200420WA CaO19.2089; hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D CAALFM_C102860CA YKT6; palmitoyltransferase K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D CAALFM_CR03970CA SEC22; SNAP receptor K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D CAALFM_C600410CA SRO77; putative Rab GTPase-binding protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D CAALFM_C702320WA SEC1; Sec1p K15292 STXBP1; syntaxin-binding protein 1
D CAALFM_C406810CA CaO19.3128; syntaxin-binding protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D CAALFM_C306990WA CaO19.6802; palmitoyltransferase K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D CAALFM_CR00870CA CaO19.3267; palmitoyltransferase K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D CAALFM_C113220CA AKR1; palmitoyltransferase K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D CAALFM_C113580WA SEC18; AAA family ATPase K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D CAALFM_CR01350CA CaO19.2518; hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D CAALFM_C201350CA SNX4; Snx4p K17919 SNX4; sorting nexin-4
D CAALFM_C403810WA CaO19.1297; hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D CAALFM_C201310WA CaO19.1994; hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D CAALFM_C202000WA CaO19.1514; hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D CAALFM_C110790WA CDC48; AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D CAALFM_CR01610CA SHP1; protein phosphatase regulator K14012 NSFL1C; UBX domain-containing protein 1
D CAALFM_C102850WA CaO19.2973; hypothetical protein K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D CAALFM_C602120WA CHC1; clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D CAALFM_C305520CA DNM1; dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D CAALFM_C107590CA CaO19.2786; hypothetical protein K11824 AP2A; AP-2 complex subunit alpha
D CAALFM_C114040WA CaO19.7212; hypothetical protein K11825 AP2B1; AP-2 complex subunit beta-1
D CAALFM_C207880WA APM4; Apm4p K11826 AP2M1; AP-2 complex subunit mu-1
D CAALFM_C111800CA CaO19.1136; hypothetical protein K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D CAALFM_C400420CA CaO19.5671; hypothetical protein K20042 FCHO; F-BAR domain only protein
D CAALFM_C202340CA ENT3; Ent3p K12471 EPN; epsin
D CAALFM_C201390WA CaO19.1444; epsin K12471 EPN; epsin
D CAALFM_C111540CA CTA3; Cta3p K12472 EPS15; epidermal growth factor receptor substrate 15
D CAALFM_C400590CA CaO19.4184; hypothetical protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D CAALFM_C604040CA RVS167; amphiphysin K12562 AMPH; amphiphysin
D CAALFM_C108840WA CaO19.4742; hypothetical protein K12562 AMPH; amphiphysin
D CAALFM_C201640WA SLA1; cytoskeletal protein-binding protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D CAALFM_C203380WA PAN1; Pan1p K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D CAALFM_C301400WA END3; End3p K20048 END3; actin cytoskeleton-regulatory complex protein END3
D CAALFM_C113480WA HSP70; Hsp70 family chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CAALFM_CR08090WA SSB1; Hsp70 family ATPase K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CAALFM_C104300CA SSA2; Hsp70 family chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D CAALFM_C301160WA MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D CAALFM_C110420CA CaO19.983; hypothetical protein K20059 LDB19; arrestin-related trafficking adapter 1
D CAALFM_C110180CA ECM21; Ecm21p K20060 ECM21; arrestin-related trafficking adapter 2/8
D CAALFM_C603180CA CaO19.5605; hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D CAALFM_C103400WA CaO19.3041; hypothetical protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D CAALFM_C201970CA ROD1; Rod1p K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D CAALFM_C100150CA RIM8; Rim8p K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D CAALFM_C700670CA CaO19.7052; phosphatidylinositol-3-/phosphoinositide 5-phosphatase K20279 SYNJ; synaptojanin [EC:3.1.3.36]
D CAALFM_C209770CA INP51; phosphoinositide 5-phosphatase K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D CAALFM_CR02040WA PRK1; serine/threonine protein kinase K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D CAALFM_C104780CA CaO19.765; hypothetical protein K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D CAALFM_C208500WA RSP5; NEDD4 family E3 ubiquitin-protein ligase K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D CAALFM_C703810WA SLA2; Sla2p K20040 HIP1R; huntingtin-interacting protein 1-related protein
D CAALFM_C404090CA CaO19.5300; calnexin K08054 CANX; calnexin
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D CAALFM_C305520CA DNM1; dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D CAALFM_C304470WA PKC1; protein kinase C K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D CAALFM_C108450CA CDC42; Rho family GTPase K04393 CDC42; cell division control protein 42
D CAALFM_C304950WA ARF2; Arf family GTPase K07937 ARF1_2; ADP-ribosylation factor 1/2
D CAALFM_CR08700CA ARF1; Arf1p K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D CAALFM_C301470WA ARF3; Arf3p K07941 ARF6; ADP-ribosylation factor 6
D CAALFM_C106730WA RAC1; Rho family GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D CAALFM_CR02860WA RHO1; Rho family GTPase K04513 RHOA; Ras homolog gene family, member A
D CAALFM_C305520CA DNM1; dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D CAALFM_C405100CA MYO5; myosin 5 K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D CAALFM_C210210CA RAS1; Ras family GTPase K07827 KRAS; GTPase KRas
D CAALFM_C304480CA RAS2; Ras2p K07827 KRAS; GTPase KRas
D CAALFM_C106730WA RAC1; Rho family GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D CAALFM_C108450CA CDC42; Rho family GTPase K04393 CDC42; cell division control protein 42
C Kinases
D CAALFM_C106680WA VPS34; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CAALFM_C201990CA FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D CAALFM_C502340CA CST20; mitogen-activated protein kinase kinase kinase kinase K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D CAALFM_C703710CA PLC1; phosphatidylinositol phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D CAALFM_C406650WA CaO19.2867; sorting nexin 1 K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D CAALFM_C604040CA RVS167; amphiphysin K12562 AMPH; amphiphysin
D CAALFM_C108840WA CaO19.4742; hypothetical protein K12562 AMPH; amphiphysin
D CAALFM_C112730WA RVS162; Rvs162p K20120 BIN3; bridging integrator 3
D CAALFM_C700020CA RVS161; amphiphysin-like protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D CAALFM_C301500CA BZZ1; Bzz1p K20121 FNBP1; formin-binding protein 1
D CAALFM_C400420CA CaO19.5671; hypothetical protein K20042 FCHO; F-BAR domain only protein
D CAALFM_C106020WA RGD1; Rgd1p K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D CAALFM_C114100WA YPT52; Rab family GTPase K07889 RAB5C; Ras-related protein Rab-5C
D CAALFM_CR08060CA VPS21; Rab family GTPase K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D CAALFM_C602630CA CaO19.5533; guanine nucleotide exchange factor K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D CAALFM_C400350WA PEP7; Pep7p K12481 RBSN; rabenosyn-5
D CAALFM_C106680WA VPS34; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CAALFM_C601190CA VPS15; ubiquitin-binding serine/threonine protein kinase K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D CAALFM_C603300CA CaO19.5618; hypothetical protein K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D CAALFM_C304950WA ARF2; Arf family GTPase K07937 ARF1_2; ADP-ribosylation factor 1/2
D CAALFM_CR08700CA ARF1; Arf1p K07937 ARF1_2; ADP-ribosylation factor 1/2
D CAALFM_C301470WA ARF3; Arf3p K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D CAALFM_C209580WA AGE2; Age2p K12486 SMAP; stromal membrane-associated protein
D CAALFM_CR08290WA CaO19.6393; hypothetical protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D CAALFM_CR07090WA STT4; 1-phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D CAALFM_C109360CA CaO19.4798; hypothetical protein K21842 EFR3; protein EFR3
D CAALFM_C400780CA CaO19.4163; hypothetical protein K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D CAALFM_C114100WA YPT52; Rab family GTPase K07889 RAB5C; Ras-related protein Rab-5C
D CAALFM_CR08060CA VPS21; Rab family GTPase K07889 RAB5C; Ras-related protein Rab-5C
D CAALFM_C206910WA YPT72; Rab family GTPase K07897 RAB7A; Ras-related protein Rab-7A
D CAALFM_C102870WA YPT7; Ypt7p K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D CAALFM_C205650WA VPS35; retromer subunit K18468 VPS35; vacuolar protein sorting-associated protein 35
D CAALFM_C100320WA CaO19.6076; retromer subunit K18467 VPS29; vacuolar protein sorting-associated protein 29
D CAALFM_C303880CA PEP8; retromer subunit K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C Rab associated proteins
D CAALFM_C106680WA VPS34; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CAALFM_CR04550WA PRE6; proteasome core particle subunit alpha 4 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D CAALFM_CR05900WA CaO19.6624; hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D CAALFM_C703490WA GYP7; Gyp7p K20168 TBC1D15; TBC1 domain family member 15
D CAALFM_C307170CA CaO19.6783; GTPase-activating protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D CAALFM_C104070CA BET4; Rab geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D CAALFM_CR09890CA BET2; Rab geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D CAALFM_C305510WA CaO19.6986; hypothetical protein K20176 SGSM3; small G protein signaling modulator 3
D CAALFM_C202000WA CaO19.1514; hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D CAALFM_C401760WA CaO19.4617; peptide alpha-N-acetyltransferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D CAALFM_C302210CA CaO19.1624; hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D CAALFM_C501020CA hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D CAALFM_C100750CA VPS27; ESCRT-0 subunit protein K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D CAALFM_CR01210CA HSE1; ESCRT-0 subunit protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D CAALFM_C110760WA VPS23; ubiquitin-binding ESCRT-I subunit protein K12183 TSG101; ESCRT-I complex subunit TSG101
D CAALFM_C208940CA VPS28; ESCRT-I subunit protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D CAALFM_C501620CA VPS22; ESCRT-II subunit protein K12188 SNF8; ESCRT-II complex subunit VPS22
D CAALFM_C504580CA CaO19.3942; ESCRT-II subunit protein K12189 VPS25; ESCRT-II complex subunit VPS25
D CAALFM_C204250WA VPS36; ESCRT-II subunit protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D CAALFM_C502830WA CaO19.4307; hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D CAALFM_C500440CA VPS2; ESCRT-III subunit protein K12191 CHMP2A; charged multivesicular body protein 2A
D CAALFM_C200930CA VPS24; ESCRT-III subunit protein K12193 VPS24; charged multivesicular body protein 3
D CAALFM_C100650CA SNF7; ESCRT-III subunit protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D CAALFM_C601830WA CTA1; Cta1p K12198 CHMP5; charged multivesicular body protein 5
D CAALFM_C203310CA VPS20; ESCRT-III subunit protein K12195 CHMP6; charged multivesicular body protein 6
D CAALFM_C405160CA CaO19.746; hypothetical protein K15053 CHMP7; charged multivesicular body protein 7
D CAALFM_C503090WA VPS4; AAA family ATPase K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D CAALFM_C111920WA CaO19.5275; hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D CAALFM_C109380WA RIM20; Rim20p K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D CAALFM_CR10590WA CaO19.7642; CORVET complex subunit K20177 VPS3; vacuolar protein sorting-associated protein 3
D CAALFM_C300700WA VPS8; CORVET complex membrane-binding subunit K20178 VPS8; vacuolar protein sorting-associated protein 8
D CAALFM_C405910CA VPS11; tethering complex subunit K20179 VPS11; vacuolar protein sorting-associated protein 11
D CAALFM_C104540CA VPS16; tethering complex subunit K20180 VPS16; vacuolar protein sorting-associated protein 16
D CAALFM_C603020WA PEP3; tethering complex subunit K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C603520CA CaO19.5718; hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C602720CA CaO19.5543; hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C205940CA VPS33; tethering complex ATP-binding subunit K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D CAALFM_C405910CA VPS11; tethering complex subunit K20179 VPS11; vacuolar protein sorting-associated protein 11
D CAALFM_C104540CA VPS16; tethering complex subunit K20180 VPS16; vacuolar protein sorting-associated protein 16
D CAALFM_C603020WA PEP3; tethering complex subunit K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C603520CA CaO19.5718; hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C602720CA CaO19.5543; hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CAALFM_C205940CA VPS33; tethering complex ATP-binding subunit K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D CAALFM_C202440WA CaO19.1567; hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D CAALFM_C109920WA VPS41; Vps41p K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D CAALFM_C300630WA CaO19.5395; hypothetical protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D CAALFM_C300630WA CaO19.5395; hypothetical protein K24155 DMXL; rabconnectin-3a
D CAALFM_C602850WA RAV2; Rav2p K25485 RAV2; regulator of V-ATPase in vacuolar membrane protein 2
D CAALFM_C107410CA SKP1; SCF ubiquitin ligase subunit K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D CAALFM_C302590WA APL5; Apl5p K12396 AP3D; AP-3 complex subunit delta
D CAALFM_C403560WA CaO19.1323; hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D CAALFM_C600430CA CaO19.1204; hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D CAALFM_C108480CA APS3; Aps3p K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D CAALFM_C103140WA CaO19.3007; hypothetical protein K22240 CNL1; biogenesis of lysosome-related organelles complex 1 subunit CNL1
D CAALFM_C505010WA CaO19.3992; hypothetical protein K22241 SNN1; biogenesis of lysosome-related organelles complex 1 subunit SNN1
D CAALFM_C302580CA CaO19.247; hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D CAALFM_CR03960CA CaO19.479; hypothetical protein K20195 MON1; vacuolar fusion protein MON1
D CAALFM_C603580WA CaO19.5726; hypothetical protein K21156 CCZ1; vacuolar fusion protein CCZ1, fungi type
D CAALFM_C114000CA DOA4; ubiquitin-specific protease K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D CAALFM_C501210WA VPS1; dynamin-like GTPase K23481 VPS1; vacuolar protein sorting-associated protein 1
D CAALFM_C106520CA BPH1; Bph1p K24781 BPH1; beige protein homolog 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D CAALFM_CR07520CA YPT31; Rab family GTPase K07905 RAB11B; Ras-related protein Rab-11B
C Rab4 associated proteins
D CAALFM_C400350WA PEP7; Pep7p K12481 RBSN; rabenosyn-5
D CAALFM_C201350CA SNX4; Snx4p K17919 SNX4; sorting nexin-4
C Rab11 associated proteins
D CAALFM_C114250CA CaO19.7235; hypothetical protein K20241 WDR44; WD repeat-containing protein 44
D CAALFM_C303170WA SEC13; GTPase-activating protein K14004 SEC13; protein transport protein SEC13
D CAALFM_C404290WA SEC15; Rab GTPase-binding exocyst subunit K19985 EXOC6; exocyst complex component 6
D CAALFM_C210610WA GYP5; Gyp5p K20242 EVI5; ecotropic viral integration site 5 protein
D CAALFM_C202000WA CaO19.1514; hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D CAALFM_C602630CA CaO19.5533; guanine nucleotide exchange factor K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D CAALFM_CR02200CA RAD51; recombinase K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D CAALFM_CR10710CA VPS52; Vps52p K20298 VPS52; vacuolar protein sorting-associated protein 52
D CAALFM_C100130CA VPS53; Vps53p K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D CAALFM_CR01180WA CaO19.3235; hypothetical protein K10364 CAPZA; F-actin-capping protein subunit alpha
D CAALFM_C401950WA CaO19.4597; F-actin-capping protein subunit beta K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D CAALFM_C100320WA CaO19.6076; retromer subunit K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D CAALFM_CR06520CA CaO19.714; Rab family GTPase K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D CAALFM_C202000WA CaO19.1514; hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D CAALFM_C405600WA GYP2; Gyp2p K19951 TBC1D8_9; TBC1 domain family member 8/9
D CAALFM_C307740WA CaO19.6712; hypothetical protein K20286 TMF1; TATA element modulatory factor
D CAALFM_CR04030WA NIP100; Nip100p K04648 DCTN1; dynactin 1
D CAALFM_C406060WA VPS13; membrane morphogenesis protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D CAALFM_C304950WA ARF2; Arf family GTPase K07937 ARF1_2; ADP-ribosylation factor 1/2
D CAALFM_CR08700CA ARF1; Arf1p K07937 ARF1_2; ADP-ribosylation factor 1/2
D CAALFM_C401890CA ARL1; Arf family GTPase K07942 ARL1; ADP-ribosylation factor-like protein 1
D CAALFM_C111190WA ARL3; Arf family GTPase K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D CAALFM_C102260CA AGE3; Age3p K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D CAALFM_C300240CA GLO3; ADP-ribosylation factor GTPase-activating protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D CAALFM_C209580WA AGE2; Age2p K12486 SMAP; stromal membrane-associated protein
D CAALFM_CR08290WA CaO19.6393; hypothetical protein K12486 SMAP; stromal membrane-associated protein
D CAALFM_C103480CA AGE1; Age1p K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D CAALFM_C304820CA SEC7; Arf family guanine nucleotide exchange factor K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D CAALFM_C301390CA GEA2; Arf family guanine nucleotide exchange factor K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D CAALFM_CR02630CA CaO19.2822; Golgi transport complex subunit K20289 COG2; conserved oligomeric Golgi complex subunit 2
D CAALFM_C107270WA SEC34; Golgi transport complex subunit K20290 COG3; conserved oligomeric Golgi complex subunit 3
D CAALFM_C205680WA COG4; Golgi transport complex subunit K20291 COG4; conserved oligomeric Golgi complex subunit 4
D CAALFM_C205850CA CaO19.5209; Golgi transport complex subunit K20293 COG6; conserved oligomeric Golgi complex subunit 6
D CAALFM_C206620WA CaO19.36; Golgi transport complex subunit K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D CAALFM_C602920CA VPS51; Vps51p K20297 VPS51; vacuolar protein sorting-associated protein 51
D CAALFM_CR10710CA VPS52; Vps52p K20298 VPS52; vacuolar protein sorting-associated protein 52
D CAALFM_C100130CA VPS53; Vps53p K20299 VPS53; vacuolar protein sorting-associated protein 53
D CAALFM_C201170CA CaO19.2007; hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D CAALFM_C303060WA CaO19.302; TRAPP subunit K20300 TRAPPC1; trafficking protein particle complex subunit 1
D CAALFM_C101260CA TRS20; TRAPP subunit K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CAALFM_C202870WA CaO19.5817; TRAPP complex core subunit K20302 TRAPPC3; trafficking protein particle complex subunit 3
D CAALFM_C102160WA CaO19.3673; TRAPP subunit K20303 TRAPPC4; trafficking protein particle complex subunit 4
D CAALFM_CR10390WA CaO19.7615; TRAPP subunit K20280 TRAPPC5; trafficking protein particle complex subunit 5
D CAALFM_C702180CA TRS33; Trs33p K20304 TRAPPC6; trafficking protein particle complex subunit 6
D CAALFM_C112520WA GSG1; Gsg1p K20305 TRAPPC8; trafficking protein particle complex subunit 8
D CAALFM_CR10290CA CaO19.7604; hypothetical protein K20306 TRAPPC9; trafficking protein particle complex subunit 9
D CAALFM_C405790WA CaO19.1265; transport protein particle complex II subunit K20307 TRAPPC10; trafficking protein particle complex subunit 10
D CAALFM_C105320CA CaO19.433; hypothetical protein K20311 TRS65; trafficking protein particle complex II-specific subunit 65
D CAALFM_C406460CA CaO19.2888; hypothetical protein K20312 TCA17; TRAPP-associated protein TCA17
B Others
C AP-1 complex
D CAALFM_CR02870WA APL4; Apl4p K12391 AP1G1; AP-1 complex subunit gamma-1
D CAALFM_C302430WA APL2; Apl2p K12392 AP1B1; AP-1 complex subunit beta-1
D CAALFM_C505400WA APM1; Apm1p K12393 AP1M; AP-1 complex subunit mu
D CAALFM_CR05310WA CaO19.1012; hypothetical protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D CAALFM_C302590WA APL5; Apl5p K12396 AP3D; AP-3 complex subunit delta
D CAALFM_C403560WA CaO19.1323; hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D CAALFM_C600430CA CaO19.1204; hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D CAALFM_C108480CA APS3; Aps3p K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D CAALFM_C103130CA GGA2; phosphatidylinositol 4-phosphate-binding protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D CAALFM_CR01080WA CaO19.3247; hypothetical protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D CAALFM_C111590WA PLD1; phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D CAALFM_CR07090WA STT4; 1-phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D CAALFM_C301160WA MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D CAALFM_C201990CA FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D CAALFM_C704330CA SYS1; Sys1p K20318 SYS1; protein SYS1
D CAALFM_C204540CA GDT1; putative ribosome biosynthesis protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D CAALFM_C112260WA VPH2; Vph2p K23542 TMEM199; TMEM199 family protein
D CAALFM_CR09720WA VMA22; Vma22p K23543 CCDC115; coiled-coil domain-containing protein 115
D CAALFM_C112580WA CaO19.3758; hypothetical protein K23544 SERINC1; serine incorporator 1
D CAALFM_C108340CA CaO19.5114; hypothetical protein K17918 SNX3_12; sorting nexin-3/12
D CAALFM_C700790WA CaO19.7039; hypothetical protein K17922 SNX8; sorting nexin-8
D CAALFM_C113120CA MON2; Mon2p K26678 MON2; protein MON2
D CAALFM_C502050WA CaO19.3166; hypothetical protein K26680 DOP1; protein dopey
D CAALFM_C407240WA CaO19.3076; hypothetical protein K26750 TVP15; golgi apparatus membrane protein TVP15
D CAALFM_C109800CA TVP18; Tvp18p K26751 TVP18; golgi apparatus membrane protein TVP18
D CAALFM_C109950CA CaO19.4862; hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
D CAALFM_C602640CA CaO19.5534; hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D CAALFM_C501210WA VPS1; dynamin-like GTPase K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D CAALFM_C602220WA SAR1; Arf family GTPase K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D CAALFM_C303170WA SEC13; GTPase-activating protein K14004 SEC13; protein transport protein SEC13
D CAALFM_C106930WA PGA63; Pga63p K14005 SEC31; protein transport protein SEC31
D CAALFM_C302080WA CaO19.1638; hypothetical protein K14006 SEC23; protein transport protein SEC23
D CAALFM_C701660CA CaO19.6558; hypothetical protein K14006 SEC23; protein transport protein SEC23
D CAALFM_C405690WA SEC23; GTPase-activating protein K14006 SEC23; protein transport protein SEC23
D CAALFM_C203410WA CaO19.880; hypothetical protein K14007 SEC24; protein transport protein SEC24
D CAALFM_C108740CA SEC24; COPII subunit K14007 SEC24; protein transport protein SEC24
D CAALFM_C601760WA SEC12; Sec12p K14003 PREB; prolactin regulatory element-binding protein
D CAALFM_C503140CA CaO19.4346; hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D CAALFM_C303060WA CaO19.302; TRAPP subunit K20300 TRAPPC1; trafficking protein particle complex subunit 1
D CAALFM_C101260CA TRS20; TRAPP subunit K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CAALFM_C202870WA CaO19.5817; TRAPP complex core subunit K20302 TRAPPC3; trafficking protein particle complex subunit 3
D CAALFM_C102160WA CaO19.3673; TRAPP subunit K20303 TRAPPC4; trafficking protein particle complex subunit 4
D CAALFM_CR10390WA CaO19.7615; TRAPP subunit K20280 TRAPPC5; trafficking protein particle complex subunit 5
D CAALFM_C702180CA TRS33; Trs33p K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D CAALFM_C110940CA ERP5; Erp5p K20346 TMED4_9_11; p24 family protein alpha
D CAALFM_CR07590WA EMP24; Emp24p K20347 TMED2; p24 family protein beta-1
D CAALFM_C306250WA ERV25; Erv25p K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D CAALFM_C703250CA PDI1; protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D CAALFM_C504340WA CaO19.3920; protein disulfide isomerase K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D CAALFM_C301140WA CaO19.2516; hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D CAALFM_C103500WA YPT1; Rab family GTPase K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D CAALFM_C106480CA hypothetical protein K20359 RABAC1; PRA1 family protein 1
D CAALFM_C502910CA GYP8; Gyp8p K20372 TBC1D20; TBC1 domain family member 20
D CAALFM_C404710WA GYP1; Gyp1p K20360 TBC1D22; TBC1 domain family member 2
D CAALFM_CR05700CA CaO19.6642; hypothetical protein K20362 YIF1; protein transport protein YIF1
D CAALFM_C202800WA hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
D CAALFM_C405280WA USO1; Uso1p K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D CAALFM_CR07180WA EMP46; Emp46p K10080 LMAN1; lectin, mannose-binding 1
D CAALFM_C207810WA CaO19.2200; hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D CAALFM_C103730CA MNS1; mannosyl-oligosaccharide 1,2-alpha-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D CAALFM_C304780CA CaO19.5941; hypothetical protein K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D CAALFM_C500830CA ERV46; Erv46p K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D CAALFM_C307130WA CaO19.6787; cornichon family protein K20368 CNIH; protein cornichon
D CAALFM_C402120WA ERV29; Erv29p K20369 ERV29; ER-derived vesicles protein
D CAALFM_C201120WA KAR2; Hsp70 family ATPase K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D CAALFM_C301720CA CaO19.1672; coatomer subunit alpha K05236 COPA; coatomer subunit alpha
D CAALFM_CR04380CA SEC26; coatomer subunit beta K17301 COPB1; coatomer subunit beta
D CAALFM_C602260CA SEC27; coatomer subunit beta' K17302 COPB2; coatomer subunit beta'
D CAALFM_C104830WA SEC21; coatomer subunit gamma K17267 COPG; coatomer subunit gamma
D CAALFM_C502300CA RET2; coatomer subunit delta K20471 COPD; coatomer subunit delta
D CAALFM_C500080CA CaO19.5689; coatomer subunit epsilon K17268 COPE; coatomer subunit epsilon
D CAALFM_CR03600CA CaO19.4382; coatomer subunit zeta K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D CAALFM_C505110CA TIP20; Tip20p K20474 RINT1; RAD50-interacting protein 1
D CAALFM_CR06940WA DSL1; Dsl1p K11578 ZW10; protein transport protein DSL1/ZW10
D CAALFM_CR07350WA CaO19.6134; hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D CAALFM_C200320WA CaO19.2101; GET complex subunit K22384 GET1; tail-anchored protein insertion receptor
D CAALFM_C109750WA CaO19.4839; GET complex subunit K22386 GET2; GET complex subunit GET2
D CAALFM_C102760WA CaO19.2965; guanine nucleotide exchange factor K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D CAALFM_C502210WA CaO19.4228; hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
D CAALFM_CR06520CA CaO19.714; Rab family GTPase K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D CAALFM_C100690WA RIC1; Ric1p K20476 RIC1; RAB6A-GEF complex partner protein 1
D CAALFM_C203340WA CaO19.894; hypothetical protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D CAALFM_C402460WA CaO19.2756; hypothetical protein K10949 KDELR; ER lumen protein retaining receptor
D CAALFM_C400350WA PEP7; Pep7p K12481 RBSN; rabenosyn-5
D CAALFM_C404710WA GYP1; Gyp1p K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D CAALFM_C108180CA CaO19.5095; oxysterol-binding protein related protein K20456 OSBP; oxysterol-binding protein 1
D CAALFM_C403590CA OSH3; oxysterol-binding protein related protein K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D CAALFM_C501770CA OBPA; oxysterol-binding protein related protein K22285 OSBPL8; oxysterol-binding protein-related protein 8
D CAALFM_C205720CA CaO19.6883; oxysterol-binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D CAALFM_C112920CA CaO19.4922; hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D CAALFM_C504660CA TIP1; transporter K20363 YIPF5_7; protein YIPF5/7
D CAALFM_C307350WA CaO19.6756; hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D CAALFM_C501410CA CaO19.4131; hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D CAALFM_C504550WA CaO19.3939; hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D CAALFM_C702470CA CaO19.6462; hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D CAALFM_C703980WA CaO19.7183; chaperone K23565 EMC4; ER membrane protein complex subunit 4
D CAALFM_CR02380CA CaO19.3730; hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D CAALFM_C402950CA CaO19.2698; hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
C SEC61 complex
D CAALFM_C307810CA SEC61; translocon subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D CAALFM_C105530CA SSH1; Ssh1p K10956 SEC61A; protein transport protein SEC61 subunit alpha
D CAALFM_CR01490CA Arf family guanine nucleotide exchange factor K09481 SEC61B; protein transport protein SEC61 subunit beta
D CAALFM_C306750WA translocon subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D CAALFM_C207010WA CaO19.2257; hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D CAALFM_C104190CA CaO19.1053; hypothetical protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D CAALFM_C502320CA CaO19.4240; hypothetical protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D CAALFM_C503460CA CaO19.2637; hypothetical protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D CAALFM_C505210WA CaO19.4014; hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D CAALFM_C407200CA CaO19.3083; putative lipid phosphatase K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D CAALFM_C406810CA CaO19.3128; syntaxin-binding protein K19998 SCFD1; sec1 family domain-containing protein 1
D CAALFM_C102000WA CaO19.4525; hypothetical protein K20724 TMEM33; transmembrane protein 33
D CAALFM_C104200CA CaO19.1054; nucleoporin K20724 TMEM33; transmembrane protein 33
D CAALFM_C304710WA ARV1; sterol homeostasis protein K21848 ARV1; lipid intermediate transporter
D CAALFM_CR05140WA CaO19.640; hypothetical protein K21849 KEG1; beta-1,6-glucan synthesis-associated protein KEG1
D CAALFM_C305810CA SKN1; Skn1p K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D CAALFM_C305830WA KRE6; beta-glucan synthesis-associated protein K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D CAALFM_C303500WA SKN2; Skn2p K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D CAALFM_C500470CA KRE62; Kre62p K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D CAALFM_C202000WA CaO19.1514; hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D CAALFM_C304130WA CaO19.5857; hypothetical protein K23292 LNPK; endoplasmic reticulum junction formation protein lunapark
D CAALFM_C302820CA CaO19.273; hypothetical protein K26681 INSIG; insulin-induced protein
D CAALFM_C504860CA CaO19.3972; hypothetical protein K26683 GOLT1; vesicle transport protein GOT1
D CAALFM_C604570WA NAG6; dynamin-like GTPase K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D CAALFM_CR02910WA CaO19.2848; serine/threonine protein kinase regulatory subunit K08331 ATG13; autophagy-related protein 13
D CAALFM_C112150CA CaO19.5249; hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D CAALFM_C404450CA ATG1; serine/threonine protein kinase K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D CAALFM_CR02910WA CaO19.2848; serine/threonine protein kinase regulatory subunit K08331 ATG13; autophagy-related protein 13
D CAALFM_C102910CA CaO19.2982; protein kinase regulatory subunit K08329 ATG17; autophagy-related protein 17
C PI3K complex
D CAALFM_C106680WA VPS34; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CAALFM_C601190CA VPS15; ubiquitin-binding serine/threonine protein kinase K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D CAALFM_C402670WA CaO19.2733; beclin 1 K08334 BECN; beclin
C ATG9 transmembrane protein
D CAALFM_C305040CA ATG9; autophagy protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D CAALFM_C100430WA CaO19.6064; phosphoinositide binding protein K17908 WIPI1_2; autophagy-related protein 18
D CAALFM_C103330CA CaO19.3030; hypothetical protein K17908 WIPI1_2; autophagy-related protein 18
D CAALFM_C206010WA SPO72; Spo72p K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D CAALFM_C113950CA CaO19.5033; hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
D CAALFM_CR06730WA APG7; Apg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D CAALFM_C102200CA CaO19.3677; hypothetical protein K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D CAALFM_C105700WA AUT7; ubiquitin-like protein K08341 GABARAP; GABA(A) receptor-associated protein
D CAALFM_CR03220CA CaO19.2401; cysteine protease K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D CAALFM_CR06730WA APG7; Apg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D CAALFM_C100860WA CaO19.6020; hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D CAALFM_C503590WA LAP4; Lap4p K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D CAALFM_C302170CA LAP41; metalloaminopeptidase K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D CAALFM_C402360WA AMS1; alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D CAALFM_C110820CA CaO19.2335; aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D CAALFM_C401790WA CaO19.4614; autophagy protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D CAALFM_C403810WA CaO19.1297; hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D CAALFM_C201310WA CaO19.1994; hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D CAALFM_C201350CA SNX4; Snx4p K17919 SNX4; sorting nexin-4
D CAALFM_C601740CA ATG15; triglyceride lipase K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D CAALFM_C210470CA CaO19.5322; hypothetical protein K21141 ATG27; autophagy-related protein 27
D CAALFM_C405150WA VAC8; protein anchor K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D CAALFM_C401790WA CaO19.4614; autophagy protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D CAALFM_C404260CA FZO1; mitofusin K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C Other mitophagy associated proteins
D CAALFM_CR04510WA HXK2; hexokinase 2 K00844 HK; hexokinase [EC:2.7.1.1]
D CAALFM_CR07490CA GLK4; Glk4p K00844 HK; hexokinase [EC:2.7.1.1]
D CAALFM_CR07150WA GLK1; glucokinase K00844 HK; hexokinase [EC:2.7.1.1]
D CAALFM_C604580WA HXK1; hexokinase 1 K00844 HK; hexokinase [EC:2.7.1.1]
D CAALFM_C104360CA hypothetical protein K22255 ATPIF1; ATPase inhibitor, mitochondrial
D CAALFM_C701890CA TOM7; Tom7p K17771 TOM7; mitochondrial import receptor subunit TOM7
D CAALFM_C210170CA CaO19.1764; hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D CAALFM_C107420CA PEX3; Pex3p K13336 PEX3; peroxin-3
D CAALFM_CR04930WA PEX14; Pex14p K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D CAALFM_C702490WA PEX1; AAA family ATPase peroxin 1 K13338 PEX1; peroxin-1
D CAALFM_C205440WA PEX6; AAA family ATPase peroxin 6 K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D CAALFM_C110790WA CDC48; AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D CAALFM_CR02050CA HDA1; histone deacetylase K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D CAALFM_C405250WA CaO19.6864; hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D CAALFM_CR07620WA AAT21; aspartate transaminase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D CAALFM_C401200CA AAT22; Aat22p K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D CAALFM_C306870WA TDH3; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CAALFM_C104320WA GPM2; Gpm2p K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D CAALFM_C203270WA GPM1; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D CAALFM_C205460WA CDC19; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CAALFM_C210670WA CaO19.5345; hypothetical protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D CAALFM_C113480WA HSP70; Hsp70 family chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CAALFM_CR08090WA SSB1; Hsp70 family ATPase K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CAALFM_C104300CA SSA2; Hsp70 family chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CAALFM_C702030WA HSP90; Hsp90 family chaperone K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D CAALFM_C208370CA TEF1; translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D CAALFM_C108380WA TEF2; translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D CAALFM_C501450WA PRC2; Prc2p K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D CAALFM_C105770CA PRC3; carboxypeptidase C K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D CAALFM_C703360WA CPY1; carboxypeptidase C K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D CAALFM_C405150WA VAC8; protein anchor K08332 VAC8; vacuolar protein 8
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D CAALFM_C404260CA FZO1; mitofusin K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D CAALFM_C207330WA TOR1; phosphatidylinositol kinase-related protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D CAALFM_CR06090WA CaO19.3862; TOR complex subunit K08266 MLST8; target of rapamycin complex subunit LST8
D CAALFM_C105460WA KOG1; ubiquitin-binding TORC1 subunit K07204 RAPTOR; regulatory associated protein of mTOR
D CAALFM_C104810WA TCO89; Tco89p K25579 TCO89; target of rapamycin complex 1 subunit TCO89
C mTORC2 complex
D CAALFM_C207330WA TOR1; phosphatidylinositol kinase-related protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D CAALFM_CR06090WA CaO19.3862; TOR complex subunit K08266 MLST8; target of rapamycin complex subunit LST8
D CAALFM_C112430WA CaO19.5221; hypothetical protein K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D CAALFM_CR07580CA TSC11; TORC2 complex subunit K08267 RICTOR; rapamycin-insensitive companion of mTOR
D CAALFM_C208920WA CaO19.215; hypothetical protein K25576 AVO2; target of rapamycin complex 2 subunit AVO2
C SEACIT/GATOR1 complex
D CAALFM_C102610WA IML1; Iml1p K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D CAALFM_C303290CA NPR2; nitrogen permease regulating protein K20405 NPRL2; nitrogen permease regulator 2
D CAALFM_CR08680CA CaO19.6444; hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D CAALFM_CR10510WA CaO19.7629; hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D CAALFM_CR01130WA CaO19.3241; hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D CAALFM_C304460WA CaO19.5897; hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D CAALFM_C207950WA SEH1; Seh1p K14299 SEH1; nucleoporin SEH1
D CAALFM_C303170WA SEC13; GTPase-activating protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D CAALFM_C103500WA YPT1; Rab family GTPase K07874 RAB1A; Ras-related protein Rab-1A
D CAALFM_CR01750CA SEC4; Rab family GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D CAALFM_C301600WA PPH21; phosphoprotein phosphatase 2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D CAALFM_C401670CA CaO19.4626; hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D CAALFM_C305460WA CaO19.6984; hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D CAALFM_C111750WA AVT4; Avt4p K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D CAALFM_C209290WA hypothetical protein K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
D CAALFM_C106730WA RAC1; Rho family GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D CAALFM_C405100CA MYO5; myosin 5 K10356 MYO1; myosin I
D CAALFM_C113780WA MYO2; myosin 2 K10357 MYO5; myosin V
C Arp2/3 complex
D CAALFM_CR06180WA ARC40; Arc40p K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D CAALFM_C106080CA ARC35; Arc35p K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D CAALFM_C601140CA ARC18; Arc18p K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D CAALFM_CR01040CA ARC19; Arc19p K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D CAALFM_CR07210WA ARC15; Arc15p K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D CAALFM_CR08950WA ARP2; actin-related protein 2 K17260 ACTR2; actin-related protein 2
D CAALFM_C207320WA ARP3; actin-related protein 3 K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D CAALFM_CR09650WA WAL1; actin-binding protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D CAALFM_C402940WA ABP1; Abp1p K20520 DBNL; drebrin-like protein
D CAALFM_C203380WA PAN1; Pan1p K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D CAALFM_C604040CA RVS167; amphiphysin K12562 AMPH; amphiphysin
D CAALFM_C108840WA CaO19.4742; hypothetical protein K12562 AMPH; amphiphysin
D CAALFM_C201640WA SLA1; cytoskeletal protein-binding protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D CAALFM_C107540CA BBC1; Bbc1p K20521 BBC1; myosin tail region-interacting protein MTI1
D CAALFM_C304880WA PIN3; Pin3p K20522 LSB1_2; LAS seventeen-binding protein 1/2
D CAALFM_C204850CA CaO19.4127; hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D CAALFM_C209710CA CaO19.1381; hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D CAALFM_C105980WA CaO19.2447; 1-phosphatidylinositol 4-kinase K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D CAALFM_C108030WA PFY1; profilin K05759 PFN; profilin
D CAALFM_C500370WA COF1; cofilin K05765 CFL; cofilin
D CAALFM_CR04190WA SRV2; adenylate cyclase-binding protein K17261 CAP1_2; adenylyl cyclase-associated protein
D CAALFM_C112010CA KIP4; Kip4p K10396 KIF5; kinesin family member 5
D CAALFM_C206370CA SCP1; Scp1p K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D CAALFM_C106020WA RGD1; Rgd1p K20643 RGD1; Rho GTPase-activating protein RGD1
C Rho guanine nucleotide exchange factors (GEFs)
D CAALFM_C204050CA DCK1; Dck1p K05727 DOCK3; dedicator of cytokinesis protein 3
D CAALFM_C204040CA DCK2; Dck2p K05727 DOCK3; dedicator of cytokinesis protein 3
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2024