+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Colobus angolensis palliatus (Angola colobus)</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      105511762 MGMT; methylated-DNA--protein-cysteine methyltransferase	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
D      105507467 ALKBH2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 isoform X1	K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33] 
D      105527083 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54] 
D      105522056 ASCC3; activating signal cointegrator 1 complex subunit 3 isoform X1	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
C    BER (base exicision repair)
D      DNA glycosylases
E        105507502 UNG; uracil-DNA glycosylase	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        105509874 CCNO; cyclin-O	K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-] 
E        105506897 TDG; G/T mismatch-specific thymine DNA glycosylase isoform X1	K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] 
E        105524696 MPG; DNA-3-methyladenine glycosylase isoform X1	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
E        105503542 SMUG1; single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        105514783 MUTYH; A/G-specific adenine DNA glycosylase isoform X1	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        105517929 MBD4; methyl-CpG-binding domain protein 4 isoform X1	K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] 
E        105519062 OGG1; N-glycosylase/DNA lyase isoform X1	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
E        105505138 NEIL1; endonuclease 8-like 1	K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] 
E        105512390 NEIL2; endonuclease 8-like 2 isoform X1	K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18] 
E        105524368 NEIL3; endonuclease 8-like 3	K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18] 
E        105526467 NTHL1; endonuclease III-like protein 1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        105523150 APEX1; DNA-(apurinic or apyrimidinic site) lyase isoform X1	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
E        105505819 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1	K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          105514850 POLD1; DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
F          105515053 POLD2; DNA polymerase delta subunit 2 isoform X1	K02328 POLD2; DNA polymerase delta subunit 2 
F          105511832 POLD3; DNA polymerase delta subunit 3 isoform X1	K03504 POLD3; DNA polymerase delta subunit 3 
F          105512092 POLD4; DNA polymerase delta subunit 4 isoform X1	K03505 POLD4; DNA polymerase delta subunit 4 
E        DNA polymerase epsilon complex
F          105525634 POLE; DNA polymerase epsilon catalytic subunit A	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          105522399 POLE2; DNA polymerase epsilon subunit 2 isoform X1	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          105517550 POLE3; DNA polymerase epsilon subunit 3	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
F          105514617 POLE4; DNA polymerase epsilon subunit 4 isoform X1	K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] 
E        105511022 PCNA; proliferating cell nuclear antigen isoform X1	K04802 PCNA; proliferating cell nuclear antigen 
E        105512293 FEN1; flap endonuclease 1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        105514815 LIG1; DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
D      Short Patch-BER factors
E        105525124 POLB; DNA polymerase beta	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
E        105526943 XRCC1; DNA repair protein XRCC1 isoform X1	K10803 XRCC1; DNA-repair protein XRCC1 
E        105508754 LIG3; DNA ligase 3 isoform X1	K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] 
D      Other BER factors
E        105517056 TDP1; tyrosyl-DNA phosphodiesterase 1	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        105526260 APTX; aprataxin isoform X1	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        105514251 APLF; aprataxin and PNK-like factor	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
E        105514752 PNKP; bifunctional polynucleotide phosphatase/kinase isoform X1	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        105515188 HMGB1; high mobility group protein B1	K10802 HMGB1; high mobility group protein B1 
E        105507123 POLL; DNA polymerase lambda isoform X1	K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] 
E        105516689 PARP1; poly [ADP-ribose] polymerase 1	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
E        105523154 PARP2; poly [ADP-ribose] polymerase 2	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
E        105523814 PARP3; poly [ADP-ribose] polymerase 3 isoform X1	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
E        105524050 PARP4; LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 4	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          105517908 XPC; DNA repair protein complementing XP-C cells isoform X1	K10838 XPC; xeroderma pigmentosum group C-complementing protein 
F          105516155 RAD23B; UV excision repair protein RAD23 homolog B	K10839 RAD23; UV excision repair protein RAD23 
F          105520788 RAD23A; UV excision repair protein RAD23 homolog A isoform X1	K10839 RAD23; UV excision repair protein RAD23 
F          105525471 CETN2; centrin-2 isoform X1	K10840 CETN2; centrin-2 
E        Cul4-DDB2 complex
F          105527741 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          105523226 CUL4B; cullin-4B	K10609 CUL4; cullin 4 
F          105505927 CUL4A; cullin-4A isoform X1	K10609 CUL4; cullin 4 
F          105512302 DDB1; DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
F          105527128 DDB2; DNA damage-binding protein 2 isoform X1	K10140 DDB2; DNA damage-binding protein 2 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          105523615 POLR2A; DNA-directed RNA polymerase II subunit RPB1	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          105508301 POLR2B; DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          105509568 POLR2C; DNA-directed RNA polymerase II subunit RPB3	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          105511528 POLR2D; DNA-directed RNA polymerase II subunit RPB4	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          105527612 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          105527792 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          105512250 POLR2G; DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          105514456 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1	K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 
F          105516720 POLR2I; DNA-directed RNA polymerase II subunit RPB9	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          105503209 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          105504285 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4	K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 
E        Cul4-CSA complex
F          105527741 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          105523226 CUL4B; cullin-4B	K10609 CUL4; cullin 4 
F          105505927 CUL4A; cullin-4A isoform X1	K10609 CUL4; cullin 4 
F          105512302 DDB1; DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
F          105519028 ERCC8; DNA excision repair protein ERCC-8 isoform X1	K10570 ERCC8; DNA excision repair protein ERCC-8 
E        Other TCR factor
F          105517716 DNA excision repair protein ERCC-6 isoform X1	K10841 ERCC6; DNA excision repair protein ERCC-6 
F          105508022 UVSSA; UV-stimulated scaffold protein A	K23720 UVSSA; UV-stimulated scaffold protein A 
F          105520830 ELOF1; transcription elongation factor 1 homolog isoform X1	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        105511520 ERCC3; TFIIH basal transcription factor complex helicase XPB subunit isoform X1	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        105526890 ERCC2; TFIIH basal transcription factor complex helicase XPD subunit isoform X1	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        105508583 GTF2H1; general transcription factor IIH subunit 1 isoform X1	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        105524160 general transcription factor IIH subunit 2 isoform X1	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        105508545 general transcription factor IIH subunit 3 isoform X1	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        105516382 GTF2H3; general transcription factor IIH subunit 3	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        105513945 GTF2H4; general transcription factor IIH subunit 4 isoform X1	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        105516857 LOW QUALITY PROTEIN: cyclin-dependent kinase 7-like	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        105524204 CDK7; cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        105513381 CCNH; cyclin-H isoform X1	K06634 CCNH; cyclin H 
E        105526047 MNAT1; CDK-activating kinase assembly factor MAT1 isoform X1	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        105521940 RPA1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        105521336 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        105512623 RPA3; replication protein A 14 kDa subunit isoform X1	K10740 RPA3; replication factor A3 
E        105513501 replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
E        105508401 RPA4; replication protein A 30 kDa subunit	K10741 RPA4; replication factor A4 
D      Other NER factors
E        105509937 XPA; DNA repair protein complementing XP-A cells isoform X1	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        105526887 ERCC1; DNA excision repair protein ERCC-1 isoform X1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        105521729 ERCC4; DNA repair endonuclease XPF	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        105505883 DNA repair protein complementing XP-G cells	K10846 ERCC5; DNA excision repair protein ERCC-5 
E        105514815 LIG1; DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        105518268 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        105518796 CUL3; cullin-3 isoform X1	K03869 CUL3; cullin 3 
E        105500975 CUL5; LOW QUALITY PROTEIN: cullin-5	K10612 CUL5; cullin 5 
E        105508319 TCEB1; transcription elongation factor B polypeptide 1 isoform X1	K03872 ELOC; elongin-C 
E        105517645 TCEB2; transcription elongation factor B polypeptide 2	K03873 ELOB; elongin-B 
E        105514185 transcription elongation factor B polypeptide 2	K03873 ELOB; elongin-B 
E        105521838 LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 3-like	K15076 ELOA; elongin-A 
E        105517016 LOW QUALITY PROTEIN: RNA polymerase II transcription factor SIII subunit A3-like	K15076 ELOA; elongin-A 
E        105514296 transcription elongation factor B polypeptide 3 isoform X1	K15076 ELOA; elongin-A 
E        105501998 UBAP2L; ubiquitin-associated protein 2-like isoform X1	K26545 UBAP2; ubiquitin-associated protein 2 
E        105517830 UBAP2; ubiquitin-associated protein 2	K26545 UBAP2; ubiquitin-associated protein 2 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        105507514 MSH2; DNA mismatch repair protein Msh2	K08735 MSH2; DNA mismatch repair protein MSH2 
E        105506262 MSH3; DNA mismatch repair protein Msh3	K08736 MSH3; DNA mismatch repair protein MSH3 
E        105507396 MSH6; DNA mismatch repair protein Msh6 isoform X1	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        105507787 PMS1; PMS1 protein homolog 1 isoform X1	K10864 PMS1; DNA mismatch repair protein PMS1 
E        105519831 MLH1; LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh1	K08734 MLH1; DNA mismatch repair protein MLH1 
E        105506325 PMS2; mismatch repair endonuclease PMS2	K10858 PMS2; DNA mismatch repair protein PMS2 
E        105517145 MLH3; DNA mismatch repair protein Mlh3 isoform X1	K08739 MLH3; DNA mismatch repair protein MLH3 
D      DNA polymerase delta complex
E        105514850 POLD1; DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        105515053 POLD2; DNA polymerase delta subunit 2 isoform X1	K02328 POLD2; DNA polymerase delta subunit 2 
E        105511832 POLD3; DNA polymerase delta subunit 3 isoform X1	K03504 POLD3; DNA polymerase delta subunit 3 
E        105512092 POLD4; DNA polymerase delta subunit 4 isoform X1	K03505 POLD4; DNA polymerase delta subunit 4 
D      RPA (replication factor A)
E        105521940 RPA1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        105521336 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        105512623 RPA3; replication protein A 14 kDa subunit isoform X1	K10740 RPA3; replication factor A3 
E        105513501 replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
E        105508401 RPA4; replication protein A 30 kDa subunit	K10741 RPA4; replication factor A4 
D      RFC (replication factor C)
E        105516780 RFC1; replication factor C subunit 1 isoform X1	K10754 RFC1; replication factor C subunit 1 
E        105503702 RFC2; replication factor C subunit 2 isoform X1	K10755 RFC2_4; replication factor C subunit 2/4 
E        105525809 RFC4; replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
E        105515147 RFC3; replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
E        105502300 RFC5; replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        105511022 PCNA; proliferating cell nuclear antigen isoform X1	K04802 PCNA; proliferating cell nuclear antigen 
E        105521487 EXO1; exonuclease 1 isoform X1	K10746 EXO1; exonuclease 1 [EC:3.1.-.-] 
E        105515188 HMGB1; high mobility group protein B1	K10802 HMGB1; high mobility group protein B1 
E        105514815 LIG1; DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        105511095 WDR76; WD repeat-containing protein 76	K24755 WDR76; WD repeat-containing protein 76 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        105500895 MRE11A; double-strand break repair protein MRE11A	K10865 MRE11; double-strand break repair protein MRE11 
E        105518188 RAD50; DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
E        105508239 NBN; nibrin isoform X1	K10867 NBN; nibrin 
D      BRCA1-core complex
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105504760 BARD1; BRCA1-associated RING domain protein 1 isoform X1	K10683 BARD1; BRCA1-associated RING domain protein 1 
D      BRCA1-A complex
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105511629 FAM175A; BRCA1-A complex subunit Abraxas	K20774 FAM175A; BRCA1-A complex subunit Abraxas 
E        105515121 UIMC1; BRCA1-A complex subunit RAP80	K20775 UIMC1; BRCA1-A complex subunit RAP80 
E        105500397 BABAM1; BRISC and BRCA1-A complex member 1	K20776 BABAM; BRISC and BRCA1-A complex member 1 
E        105521949 BRE; BRCA1-A complex subunit BRE	K12173 BRE; BRCA1-A complex subunit BRE 
E        105527019 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1	K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
D      BRCA1-B complex
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105520076 BRIP1; Fanconi anemia group J protein	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
E        105523376 TOPBP1; DNA topoisomerase 2-binding protein 1	K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 
D      BRCA1-C complex
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105509778 RBBP8; DNA endonuclease RBBP8	K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-] 
E        105500895 MRE11A; double-strand break repair protein MRE11A	K10865 MRE11; double-strand break repair protein MRE11 
E        105518188 RAD50; DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
E        105508239 NBN; nibrin isoform X1	K10867 NBN; nibrin 
D      BRCA complex
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105515183 BRCA2; breast cancer type 2 susceptibility protein	K08775 BRCA2; breast cancer 2 susceptibility protein 
E        105523506 PALB2; partner and localizer of BRCA2	K10897 PALB2; partner and localizer of BRCA2 
E        105505024 RAD51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        105505024 RAD51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
E        105517236 RAD51B; DNA repair protein RAD51 homolog 2 isoform X1	K10869 RAD51L1; RAD51-like protein 1 
E        105520092 RAD51C; DNA repair protein RAD51 homolog 3	K10870 RAD51L2; RAD51-like protein 2 
E        105508756 RAD51D; DNA repair protein RAD51 homolog 4	K10871 RAD51L3; RAD51-like protein 3 
E        105511355 XRCC2; DNA repair protein XRCC2	K10879 XRCC2; DNA-repair protein XRCC2 
E        105518429 XRCC3; DNA repair protein XRCC3	K10880 XRCC3; DNA-repair protein XRCC3 
D      Rad52 family proteins
E        105503899 RAD52; DNA repair protein RAD52 homolog isoform X1	K10873 RAD52; DNA repair and recombination protein RAD52 
E        105518755 RDM1; RAD52 motif-containing protein 1 isoform X1	K10874 RDM1; RAD52 motif-containing protein 1 
D      Rad54 family proteins
E        105515095 RAD54L; DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
E        105509654 helicase ARIP4 isoform X1	K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] 
E        105508209 RAD54B; DNA repair and recombination protein RAD54B isoform X1	K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        105520999 RECQL; ATP-dependent DNA helicase Q1	K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] 
E        105513618 WRN; Werner syndrome ATP-dependent helicase	K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4] 
E        105515573 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        105508964 RECQL4; ATP-dependent DNA helicase Q4	K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] 
E        105514639 RECQL5; ATP-dependent DNA helicase Q5 isoform X1	K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        105515573 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        105515501 TOP3B; DNA topoisomerase 3-beta-1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        105525859 TOP3A; DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        105520329 RMI1; recQ-mediated genome instability protein 1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      RPA (replication factor A)
E        105521940 RPA1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        105521336 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        105512623 RPA3; replication protein A 14 kDa subunit isoform X1	K10740 RPA3; replication factor A3 
E        105513501 replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
E        105508401 RPA4; replication protein A 30 kDa subunit	K10741 RPA4; replication factor A4 
D      Protein phosphatase 4
E        105505638 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit isoform X1	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        105507991 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 1-like	K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 
E        105507898 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1	K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 
E        105508354 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2	K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 
E        105518738 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 2-like	K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 
E        105522858 SMEK2; serine/threonine-protein phosphatase 4 regulatory subunit 3B	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        105517046 SMEK1; serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        105506862 putative SMEK homolog 3	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        105518514 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4	K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 
D      AP-5 complex
E        105512152 AP5B1; AP-5 complex subunit beta-1	K19022 AP5B1; AP-5 complex subunit beta-1 
E        105526013 AP5M1; AP-5 complex subunit mu-1 isoform X1	K19023 AP5M1; AP-5 complex subunit mu-1 
E        105512727 AP5S1; AP-5 complex subunit sigma-1	K19024 AP5S1; AP-5 complex subunit sigma-1 
E        105522483 AP5Z1; AP-5 complex subunit zeta-1	K19025 AP5Z1; AP-5 complex subunit zeta-1 
D      SMC5-SMC6 complex
E        105516636 SMC5; structural maintenance of chromosomes protein 5	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        105518350 SMC6; structural maintenance of chromosomes protein 6	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        105511845 FAM84A; protein FAM84A	K22805 FAM84A; protein FAM84A 
E        105505599 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        105509083 NSMCE2; E3 SUMO-protein ligase NSE2	K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] 
E        105516905 NDNL2; melanoma-associated antigen G1	K22823 NSMCE3; non-structural maintenance of chromosomes element 3 
E        105503362 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A isoform X1	K22825 NSMCE4; non-structural maintenance of chromosomes element 4 
E        105506945 EID3; EP300-interacting inhibitor of differentiation 3	K22826 EID3; EP300-interacting inhibitor of differentiation 3 
E        105513413 ANKRD32; ankyrin repeat domain-containing protein 32 isoform X1	K26126 SLF1; SMC5-SMC6 complex localization factor protein 1 
E        105507137 FAM178A; protein FAM178A isoform X1	K26127 SLF2; SMC5-SMC6 complex localization factor protein 2 
D      Other HR factors
E        105524617 EME1; crossover junction endonuclease EME1 isoform X1	K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] 
E        105522885 EME2; probable crossover junction endonuclease EME2	K10883 EME2; crossover junction endonuclease EME2 
E        105517229 EXD2; exonuclease 3'-5' domain-containing protein 2 isoform X1	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        105512147 MUS81; crossover junction endonuclease MUS81	K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] 
E        105512768 SHFM1; 26S proteasome complex subunit DSS1 isoform X1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        105522751 SFR1; swi5-dependent recombination DNA repair protein 1 homolog	K10992 SFR1; Swi5-dependent recombination DNA repair protein 1 
E        105505630 SLX1A; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX1	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        105517640 SLX4; structure-specific endonuclease subunit SLX4	K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) 
E        105518498 GEN1; flap endonuclease GEN homolog 1	K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] 
E        105511103 SPG11; spatacsin isoform X1	K19026 SPG11; spatacsin 
E        105517238 ZFYVE26; zinc finger FYVE domain-containing protein 26	K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26 
E        105503936 RAD51AP1; RAD51-associated protein 1 isoform X1	K20778 RAD51AP1; RAD51-associated protein 1 
E        105509240 MORF4L1; mortality factor 4-like protein 1 isoform X1	K11339 MORF4L1; mortality factor 4-like protein 1 
E        105502525 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1	K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] 
E        105515692 FIGNL1; fidgetin-like protein 1 isoform X1	K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] 
E        105514378 SPIDR; DNA repair-scaffolding protein	K22806 SPIDR; DNA repair-scaffolding protein 
E        105509077 FAM84B; protein FAM84B	K22810 FAM84B; protein FAM84B 
E        105522479 BRAT1; LOW QUALITY PROTEIN: BRCA1-associated ATM activator 1	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        105520413 protein C21orf2 isoform X1	K23456 CFAP410; cilla- and flagella-associated protein 
E        105512942 hepatoma-derived growth factor-related protein 2	K25065 HDGFL2; hepatoma-derived growth factor-related protein 2 
E        105523184 ZSWIM7; zinc finger SWIM domain-containing protein 7 isoform X1	K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7 
E        105520839 SWSAP1; ATPase SWSAP1	K25771 SWSAP1; ATPase SWSAP1 
E        105509639 protein EMSY isoform X1	K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY 
E        105520398 HSF2BP; heat shock factor 2-binding protein	K25791 HSF2BP; heat shock factor 2-binding protein 
E        105521121 MMS22L; protein MMS22-like	K26125 MMS22L; protein MMS22-like 
E        105509094 TONSL; tonsoku-like protein	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
E        105515539 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1	K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 
E        105506734 PARPBP; PCNA-interacting partner	K27412 PARPBP; PCNA-interacting partner 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
E        105523135 LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6-like	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        105506243 LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6-like	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        105514005 XRCC6; X-ray repair cross-complementing protein 6 isoform X1	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        105504753 XRCC5; X-ray repair cross-complementing protein 5	K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 
E        105514376 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1	K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] 
D      MRX complex
E        105500895 MRE11A; double-strand break repair protein MRE11A	K10865 MRE11; double-strand break repair protein MRE11 
E        105518188 RAD50; DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
E        105505894 LIG4; DNA ligase 4 isoform X1	K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] 
E        105513368 XRCC4; DNA repair protein XRCC4 isoform X1	K10886 XRCC4; DNA-repair protein XRCC4 
E        105504709 NHEJ1; non-homologous end-joining factor 1	K10980 NHEJ1; non-homologous end-joining factor 1 
D      X-family DNA polymerases
E        105507123 POLL; DNA polymerase lambda isoform X1	K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] 
E        105515051 POLM; DNA-directed DNA/RNA polymerase mu isoform X1	K03513 POLM; DNA polymerase mu [EC:2.7.7.7] 
E        105518286 DNTT; DNA nucleotidylexotransferase isoform X1	K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31] 
E        105525124 POLB; DNA polymerase beta	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
D      Other NHEJ factors
E        105526260 APTX; aprataxin isoform X1	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        105514251 APLF; aprataxin and PNK-like factor	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
E        105506198 DCLRE1C; protein artemis isoform X1	K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-] 
E        105526710 TDP2; tyrosyl-DNA phosphodiesterase 2	K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] 
E        105523063 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1	K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 
E        105523512 PWWP domain-containing protein MUM1L1	K23386 PWWP3; PWWP domain-containing DNA repair factor 3 
E        105527623 PWWP domain-containing protein MUM1 isoform X1	K23386 PWWP3; PWWP domain-containing DNA repair factor 3 
E        105522798 protein PAXX	K25772 PAXX; protein PAXX 
E        105526480 JMJD8; jmjC domain-containing protein 8	K25792 JMJD8; jumonji domain-containing protein 8 
E        105511012 uncharacterized protein C20orf196 homolog isoform X1	K26128 SHLD1; shieldin complex subunit 1 
E        105525925 FAM35A; protein FAM35A	K26129 SHLD2; shieldin complex subunit 2 
E        105510789 uncharacterized protein LOC105510789 isoform X1	K26130 SHLD3; shieldin complex subunit 3 
C    FA (Fanconi anemia) pathway
D      FA core complex
E        105501867 FANCA; Fanconi anemia group A protein	K10888 FANCA; fanconi anemia group A protein 
E        105523122 FANCB; Fanconi anemia group B protein	K10889 FANCB; fanconi anemia group B protein 
E        105501522 FANCC; Fanconi anemia group C protein	K10890 FANCC; fanconi anemia group C protein 
E        105514265 FANCE; Fanconi anemia group E protein	K10892 FANCE; fanconi anemia group E protein 
E        105508620 FANCF; Fanconi anemia group F protein	K10893 FANCF; fanconi anemia group F protein 
E        105517792 FANCG; Fanconi anemia group G protein	K10894 FANCG; fanconi anemia group G protein 
E        105511633 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1	K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] 
E        105515286 FANCM; Fanconi anemia group M protein	K10896 FANCM; fanconi anemia group M protein 
E        105515524 Fanconi anemia-associated protein of 24 kDa	K10898 FAAP24; fanconi anemia-associated protein 
E        105524598 Fanconi anemia-associated protein of 100 kDa	K10993 FAAP100; fanconi anemia core complex 100 kDa subunit 
D      FA core complex binding factors
E        105525534 HES1; transcription factor HES-1	K06054 HES1; hairy and enhancer of split 1 
E        105507383 centromere protein S-like	K11511 APITD1; centromere protein S 
E        105527383 STRA13; centromere protein X isoform X1	K15360 STRA13; centromere protein X 
E        105504341 UBE2T; ubiquitin-conjugating enzyme E2 T	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        105515573 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        105515501 TOP3B; DNA topoisomerase 3-beta-1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        105525859 TOP3A; DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        105520329 RMI1; recQ-mediated genome instability protein 1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      FANCD2-I complex
E        105519200 FANCD2; Fanconi anemia group D2 protein	K10891 FANCD2; fanconi anemia group D2 protein 
E        105516211 FANCI; Fanconi anemia group I protein isoform X1	K10895 FANCI; fanconi anemia group I protein 
D      Downstream FA components
E        105503134 BRCA1; breast cancer type 1 susceptibility protein	K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
E        105515183 BRCA2; breast cancer type 2 susceptibility protein	K08775 BRCA2; breast cancer 2 susceptibility protein 
E        105520076 BRIP1; Fanconi anemia group J protein	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
E        105523506 PALB2; partner and localizer of BRCA2	K10897 PALB2; partner and localizer of BRCA2 
D      Other FA pathway factors
E        105516902 FAN1; fanconi-associated nuclease 1	K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] 
E        105505024 RAD51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
E        105520092 RAD51C; DNA repair protein RAD51 homolog 3	K10870 RAD51L2; RAD51-like protein 2 
E        105522872 TELO2; telomere length regulation protein TEL2 homolog	K11137 TELO2; telomere length regulation protein 
E        105511046 USP1; ubiquitin carboxyl-terminal hydrolase 1	K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] 
E        105519806 WDR48; WD repeat-containing protein 48 isoform X1	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        105504100 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit isoform X1	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        105504940 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1	K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1 
E        105512010 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2	K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 
E        105512065 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1	K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 
E        105505758 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1	K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 
E        105517446 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1	K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B 
E        105500611 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C	K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C 
D      Ubiquitin ligases
E        105513611 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X1	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        105525505 E3 ubiquitin-protein ligase RNF168	K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] 
E        105511857 RNF169; E3 ubiquitin-protein ligase RNF169	K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31] 
E        105512435 HERC2; E3 ubiquitin-protein ligase HERC2	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        105523688 WRAP53; telomerase Cajal body protein 1	K23314 WRAP53; telomerase Cajal body protein 1 
E        105522679 TPRN; taperin isoform X1	K24164 TPRN; taperin 
E        105513088 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X1	K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1 
E        105513504 WDR70; WD repeat-containing protein 70	K24752 WDR70; WD repeat-containing protein 70 
E        105511095 WDR76; WD repeat-containing protein 76	K24755 WDR76; WD repeat-containing protein 76 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      105524902 POLH; DNA polymerase eta isoform X1	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      105518128 POLI; DNA polymerase iota isoform X1	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      105524119 POLK; DNA polymerase kappa	K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] 
D      105522142 REV1; DNA repair protein REV1 isoform X1	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
D      105506746 REV3L; DNA polymerase zeta catalytic subunit isoform X1	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
C    A-family DNA polymerase
D      105508009 DNA polymerase nu isoform X1	K16618 POLN; DNA polymerase nu [EC:2.7.7.7] 
C    Rad6 epistasis group
D      105516467 UBE2A; ubiquitin-conjugating enzyme E2 A isoform X1	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      105516447 ubiquitin-conjugating enzyme E2 B isoform X1	K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] 
D      105523802 UBE2B; ubiquitin-conjugating enzyme E2 B	K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] 
D      105525601 RAD18; E3 ubiquitin-protein ligase RAD18	K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27] 
D      105523884 HLTF; helicase-like transcription factor isoform X1	K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27] 
D      105501700 ubiquitin-conjugating enzyme E2 variant 1-like isoform X1	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      105502577 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      105520510 ubiquitin-conjugating enzyme E2 variant 2-like isoform X1	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      105520631 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 variant 1-like	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      105514374 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 isoform X1	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      105515808 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105509542 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105516170 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105504558 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105525747 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105505851 UBE2N; ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105506364 ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      105513286 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      105511022 PCNA; proliferating cell nuclear antigen isoform X1	K04802 PCNA; proliferating cell nuclear antigen 
D      105506734 PARPBP; PCNA-interacting partner	K27412 PARPBP; PCNA-interacting partner 
D      105505469 SPRTN; sprT-like domain-containing protein Spartan isoform X1	K24051 SPRTN; SprT-like domain-contaning protein Spartan 
D      105512648 ACRC; acidic repeat-containing protein	K26957 GCNA; germ cell nuclear acidic protein 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      105512094 RAD9A; cell cycle checkpoint control protein RAD9A	K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] 
D      105507748 RAD9B; cell cycle checkpoint control protein RAD9B	K10995 RAD9B; cell cycle checkpoint control protein RAD9B 
D      105515082 HUS1; checkpoint protein HUS1 isoform X1	K10903 HUS1; HUS1 checkpoint protein 
D      105521095 HUS1B; checkpoint protein HUS1B	K10996 HUS1B; checkpoint protein HUS1B 
D      105508623 cell cycle checkpoint protein RAD1-like	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
D      105513476 RAD1; cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      105524203 RAD17; cell cycle checkpoint protein RAD17	K06662 HRAD17; cell cycle checkpoint protein 
D      105503702 RFC2; replication factor C subunit 2 isoform X1	K10755 RFC2_4; replication factor C subunit 2/4 
D      105525809 RFC4; replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
D      105515147 RFC3; replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
D      105502300 RFC5; replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      105508623 cell cycle checkpoint protein RAD1-like	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
D      105513476 RAD1; cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      105500609 TIMELESS; protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      105510532 TIPIN; LOW QUALITY PROTEIN: TIMELESS-interacting protein	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
D      105521432 CLSPN; claspin	K25773 CLSPN; claspin 
C    Triple T complex
D      105522872 TELO2; telomere length regulation protein TEL2 homolog	K11137 TELO2; telomere length regulation protein 
D      105502510 TTI1; TELO2-interacting protein 1 homolog	K20403 TTI1; TELO2-interacting protein 1 
D      105525191 TTI2; TELO2-interacting protein 2	K23115 TTI2; TELO2-interacting protein 2 
C    BAG6-UBL4A-GET4 complex
D      105513735 BAG6; large proline-rich protein BAG6	K23390 BAG6; large proline-rich protein BAG6 
D      105516051 UBL4B; ubiquitin-like protein 4B	K23388 UBL4; ubiquitin-like protein 4 
D      105521646 UBL4A; ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      105522412 GET4; Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      105523299 ATR; serine/threonine-protein kinase ATR	K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] 
D      105509737 ATRIP; ATR-interacting protein isoform X1	K10905 ATRIP; ATR interacting protein 
D      105500980 ATM; serine-protein kinase ATM	K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
D      105523626 TP53; cellular tumor antigen p53 isoform X1	K04451 TP53; tumor protein p53 
D      105506457 CHEK1; serine/threonine-protein kinase Chk1 isoform X1	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      105506620 CHEK2; serine/threonine-protein kinase Chk2 isoform X1	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      105509746 CDC25A; M-phase inducer phosphatase 1	K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48] 
D      105512729 CDC25B; M-phase inducer phosphatase 2 isoform X1	K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
D      105506977 CDC25C; M-phase inducer phosphatase 3	K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48] 
D      105502458 YWHAB; 14-3-3 protein beta/alpha	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      105504209 YWHAZ; 14-3-3 protein zeta/delta isoform X1	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      105525333 YWHAQ; 14-3-3 protein theta isoform X1	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      105509185 YWHAH; 14-3-3 protein eta isoform X1	K16198 YWHAG_H; 14-3-3 protein gamma/eta 
D      105503266 YWHAG; 14-3-3 protein gamma	K16198 YWHAG_H; 14-3-3 protein gamma/eta 
D      105521605 YWHAE; 14-3-3 protein epsilon isoform X1	K06630 YWHAE; 14-3-3 protein epsilon 
D      105508602 NAV2; neuron navigator 2 isoform X1	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      105515759 WEE1; wee1-like protein kinase	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      105511192 WEE2; wee1-like protein kinase 2	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      105523641 PER1; period circadian protein homolog 1	K21944 PER1; period circadian protein 1 
D      105502905 PER2; period circadian protein homolog 2	K02633 PER2; period circadian protein 2 
D      105509150 PER3; period circadian protein homolog 3 isoform X1	K21945 PER3; period circadian protein 3 
D      105513956 MDC1; mediator of DNA damage checkpoint protein 1 isoform X1	K20780 MDC1; mediator of DNA damage checkpoint protein 1 
D      105522912 PLS3; plastin-3 isoform X1	K17336 PLS3; plastin-3 
D      105516223 AEN; apoptosis-enhancing nuclease	K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-] 
D      105514662 PLK3; serine/threonine-protein kinase PLK3	K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] 
D      105527688 PLK5; inactive serine/threonine-protein kinase PLK5	K19596 PLK5; inactive serine/threonine-protein kinase PLK5 
D      105523420 NEK4; serine/threonine-protein kinase Nek4	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      105510597 serine/threonine-protein kinase Nek5	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      105524395 NEK1; serine/threonine-protein kinase Nek1 isoform X1	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      105521883 NEK10; serine/threonine-protein kinase Nek10 isoform X1	K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1] 
D      105505745 NEK11; serine/threonine-protein kinase Nek11 isoform X1	K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1] 
D      105517515 DONSON; protein downstream neighbor of Son	K22422 DONSON; protein downstream neighbor of Son 
D      105522084 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      105511063 KANK4; KN motif and ankyrin repeat domain-containing protein 4	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      105520849 KANK2; KN motif and ankyrin repeat domain-containing protein 2	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      105509511 KLLN; killin	K23389 KLLN; killin 
D      105518737 SLFN11; schlafen family member 11	K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-] 
D      105508275 CHMP4C; charged multivesicular body protein 4c	K24782 CHMP4C; charged multivesicular body protein 4C 
D      105504522 VPS4A; vacuolar protein sorting-associated protein 4A	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      105520027 VPS4B; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 4B	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      105504960 ZFYVE19; abscission/NoCut checkpoint regulator isoform X1	K24778 ZFYVE19; abscission/NoCut checkpoint regulator 
D      105516684 SDE2; protein SDE2 homolog	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      105518045 POLQ; DNA polymerase theta	K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] 
D      105523664 MYBBP1A; myb-binding protein 1A	K02331 POL5; DNA polymerase phi [EC:2.7.7.7] 
D      105524341 PRIMPOL; DNA-directed primase/polymerase protein isoform X1	K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] 
C    Nucleases
D      105509736 TREX1; three-prime repair exonuclease 1 isoform X1	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
D      105521611 TREX2; three prime repair exonuclease 2	K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2] 
D      105501789 DCLRE1A; DNA cross-link repair 1A protein	K15340 DCLRE1A; DNA cross-link repair 1A protein 
D      105505327 DCLRE1B; 5' exonuclease Apollo	K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-] 
D      105521147 EXO5; LOW QUALITY PROTEIN: exonuclease V	K17815 EXO5; exonuclease V [EC:3.1.-.-] 
D      105523596 ENDOV; endonuclease V isoform X1	K21813 ENDOV; endonuclease V [EC:3.1.26.-] 
D      105508812 ZRANB3; DNA annealing helicase and endonuclease ZRANB3	K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-] 
D      105500311 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 isoform X1	K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 
C    Helicases
D      105511613 HELQ; helicase POLQ-like isoform X1	K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] 
D      105501520 ERCC6L2; DNA excision repair protein ERCC-6-like 2	K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] 
C    PSO4 complex
D      105527278 PRPF19; pre-mRNA-processing factor 19	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      105524881 CDC5L; cell division cycle 5-like protein	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      105505317 BCAS2; pre-mRNA-splicing factor SPF27 isoform X1	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
D      105524466 PLRG1; pleiotropic regulator 1 isoform X1	K12862 PLRG1; pleiotropic regulator 1 
C    Modulation of nucleotide pools
D      105510114 NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] 
D      105510205 NUDT18; LOW QUALITY PROTEIN: 8-oxo-dGDP phosphatase NUDT18	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      105502182 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      105522325 RRM1; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      105504121 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
D      105525327 RRM2; ribonucleoside-diphosphate reductase subunit M2 isoform X1	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
#
A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      105511762 MGMT; methylated-DNA--protein-cysteine methyltransferase	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
C    BER (base exicision repair)
D      DNA glycosylases
E        105507502 UNG; uracil-DNA glycosylase	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        105503542 SMUG1; single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        105524696 MPG; DNA-3-methyladenine glycosylase isoform X1	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
E        105514783 MUTYH; A/G-specific adenine DNA glycosylase isoform X1	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        105526467 NTHL1; endonuclease III-like protein 1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        105511191 SSBP1; single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      105511191 SSBP1; single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      105510114 NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] 
D      105502182 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
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#Last updated: March 29, 2024