+F Repair protein KO
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DNA Repair and Recombination Proteins - Clostridium felsineum DSM 793
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CLAUR_003240 ogt; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CLAUR_019490 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CLAUR_040920 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CLAUR_017340 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E CLAUR_008520 dinG_1; 3'-5' exonuclease DinG K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CLAUR_003500 nudG_1; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_027260 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_038580 nudG_2; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_002440 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CLAUR_003240 ogt; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CLAUR_019760 udg; Type-4 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CLAUR_025240 tmung; Type-4 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CLAUR_019490 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CLAUR_003220 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E CLAUR_017340 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CLAUR_025210 exoA; Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CLAUR_004800 nfo; endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E CLAUR_041310 nfi; Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E CLAUR_009920 recJ_2; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E CLAUR_041420 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CLAUR_012000 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CLAUR_021080 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E CLAUR_021090 uvrB_2; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E CLAUR_016630 uvrC_1; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E CLAUR_021030 uvrC_2; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E CLAUR_013310 helD_1; DNA helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_013510 yjcD; Putative ATP-dependent DNA helicase YjcD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_016020 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_018150 helD_2; DNA helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_041410 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_012000 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CLAUR_041420 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CLAUR_035230 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CLAUR_035240 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CLAUR_035600 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CLAUR_008050 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CLAUR_034240 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CLAUR_006660 mutS_1; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E CLAUR_001200 mutS2_1; Endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
E CLAUR_029740 mutS2_2; Endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E CLAUR_006670 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E CLAUR_005540 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E CLAUR_005550 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CLAUR_020950 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CLAUR_031520 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E CLAUR_028070 dnaN_1; Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CLAUR_041910 dnaN_2; Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CLAUR_011530 yqeN; putative protein YqeN K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CLAUR_024170 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CLAUR_016490 dinG_2; 3'-5' exonuclease DinG K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CLAUR_043890 dinG_3; 3'-5' exonuclease DinG K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CLAUR_026850 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E CLAUR_041840 ruvB_2; Holliday junction ATP-dependent DNA helicase RuvB K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CLAUR_041420 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CLAUR_013310 helD_1; DNA helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_013510 yjcD; Putative ATP-dependent DNA helicase YjcD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_016020 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_018150 helD_2; DNA helicase IV K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_041410 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CLAUR_014150 ssbB; Single-stranded DNA-binding protein B K03111 ssb; single-strand DNA-binding protein
E CLAUR_028250 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CLAUR_041890 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CLAUR_038250 recD2_2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CLAUR_006880 recA; Protein RecA K03553 recA; recombination protein RecA
E CLAUR_001980 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CLAUR_001990 ruvB_1; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CLAUR_008030 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CLAUR_040660 smc_2; Chromosome partition protein Smc K03546 sbcC; DNA repair protein SbcC/Rad50
E CLAUR_040650 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E CLAUR_006880 recA; Protein RecA K03553 recA; recombination protein RecA
E CLAUR_034630 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E CLAUR_028050 recF_2; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E CLAUR_007880 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CLAUR_009920 recJ_2; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E CLAUR_011300 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E CLAUR_026830 recR; Recombination protein RecR K06187 recR; recombination protein RecR
E CLAUR_005610 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E CLAUR_001980 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CLAUR_001990 ruvB_1; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E CLAUR_002240 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E CLAUR_002230 addB; ATP-dependent helicase/deoxyribonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E CLAUR_022910 cas1_1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E CLAUR_033900 cas1_3; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E CLAUR_040660 smc_2; Chromosome partition protein Smc K03546 sbcC; DNA repair protein SbcC/Rad50
E CLAUR_040650 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CLAUR_028020 gyrA_2; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CLAUR_028030 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CLAUR_007180 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CLAUR_034290 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CLAUR_009920 recJ_2; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F CLAUR_011300 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F CLAUR_026830 recR; Recombination protein RecR K06187 recR; recombination protein RecR
F CLAUR_041420 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F CLAUR_041270 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CLAUR_021080 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F CLAUR_021090 uvrB_2; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CLAUR_024390 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D CLAUR_006880 recA; Protein RecA K03553 recA; recombination protein RecA
D CLAUR_006720 lexA_1; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D CLAUR_005610 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CLAUR_047760 dnaE1; DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D CLAUR_014150 ssbB; Single-stranded DNA-binding protein B K03111 ssb; single-strand DNA-binding protein
D CLAUR_028250 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CLAUR_041890 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CLAUR_000370 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CLAUR_003500 nudG_1; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_027260 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_038580 nudG_2; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAUR_002440 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CLAUR_012980 nrdJ; Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CLAUR_033300 nrdE; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CLAUR_033310 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D CLAUR_006990 nrnA; Bifunctional oligoribonuclease and PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024