+E Ubiquitin system KO
#
Ubiquitin System - Candidozyma auris
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C CJI96_0004384 polyubiquitin K08770 UBC; ubiquitin C
C CJI96_0003464 ubiquitin-40S_ribosomal_protein_S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C CJI96_0001598 hypothetical_protein K12158 NEDD8; ubiquitin-like protein Nedd8
C CJI96_0003871 ubiquitin-like protein ATG8 K08341 GABARAP; GABA(A) receptor-associated protein
C CJI96_0004509 hypothetical_protein K08336 ATG12; ubiquitin-like protein ATG12
C CJI96_0004092 ubiquitin-related modifier URM1 K12161 URM1; ubiquitin related modifier 1
#
AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C CJI96_0004945 ubiquitin-activating_enzyme_E1_1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C CJI96_0000119 E1 ubiquitin-activating protein AOS1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C CJI96_0003507 E1 ubiquitin-activating protein UBA2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C CJI96_0004842 hypothetical_protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CJI96_0004902 hypothetical_protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CJI96_0000968 hypothetical_protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C CJI96_0003920 E1-like_protein-activating_enzyme_Gsa7p/Apg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C CJI96_0004503 ubiquitin-conjugating_enzyme_E2_2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C CJI96_0000591 ubiquitin-conjugating_enzyme_E2_4 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C CJI96_0004643 ubiquitin-conjugating_enzyme_E2_7 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C CJI96_0004492 E2 ubiquitin-conjugating protein UBC8 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C CJI96_0003763 E2 ubiquitin-conjugating protein UBC6 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C CJI96_0000839 E2 ubiquitin-conjugating protein UBC1 K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C CJI96_0001156 ubiquitin-conjugating_enzyme_E2_13 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C CJI96_0000032 SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
B UBL-conjugating enzymes
C CJI96_0001549 SUMO-conjugating_enzyme_UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C CJI96_0002342 NEDD8-conjugating protein UBC12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C CJI96_0003729 hypothetical_protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
#
AUbiquitin ligases (E3)
B HECT type E3
C CJI96_0005440 ubiquitin-ubiquitin ligase HUL5 K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C CJI96_0003062 hypothetical_protein K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C CJI96_0005268 hypothetical_protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C CJI96_0003861 E3_ubiquitin-protein_ligase_RSP5 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C CJI96_0003579 E3 ubiquitin-protein ligase TOM1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C CJI96_0004724 hypothetical_protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C CJI96_0004234 ubiquitin-ubiquitin ligase UFD2 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C CJI96_0002107 E3 ubiquitin-protein ligase PRP19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D CJI96_0001340 hypothetical_protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D CJI96_0003418 E3 ubiquitin-protein ligase SSM4 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
C Pellino proteins
C Peripheral membrane proteins
D CJI96_0002010 ubiquitin-protein ligase peroxin 10 K13346 PEX10; peroxin-10
D CJI96_0000659 ubiquitin-protein ligase peroxin 12 K13345 PEX12; peroxin-12
D CJI96_0005042 ubiquitin-protein ligase peroxin 2 K06664 PEX2; peroxin-2
C RBR proteins
D CJI96_0001856 E3 ubiquitin-protein ligase HEL1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D CJI96_0000707 RBR-type E3 ubiquitin transferase K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D CJI96_0001228 hypothetical_protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CJI96_0004752 hypothetical_protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D CJI96_0000231 hypothetical_protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D CJI96_0000493 CCR4-NOT core ubiquitin-protein ligase subunit MOT2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D CJI96_0000516 hypothetical_protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D CJI96_0004161 DNA_repair_protein_rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CJI96_0001947 hypothetical_protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D CJI96_0005044 U4/U6-U5 snRNP complex subunit SNU66 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D CJI96_0002489 hypothetical_protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CJI96_0004193 E3 ubiquitin-protein ligase HEL2 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D CJI96_0004843 hypothetical_protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D CJI96_0004903 hypothetical_protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D CJI96_0000578 ubiquitin-protein ligase TUL1 K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D CJI96_0002841 hypothetical_protein K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
C CJI96_0005330 hypothetical_protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C CJI96_0001435 hypothetical_protein K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C CJI96_0003358 SUMO ligase MMS21 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C CJI96_0002057 NEDD8 ligase DCN1 K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit type E3
C SCF complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CJI96_0000355 cullin CDC53 K03347 CUL1; cullin 1
D Adaptor protein
E CJI96_0000082 SCF ubiquitin ligase subunit SKP1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E CJI96_0002064 hypothetical_protein K10259 MET30; F-box and WD-40 domain protein MET30
E CJI96_0000225 hypothetical_protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CJI96_0000171 hypothetical_protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E CJI96_0003410 [Histone H3]-lysine-36 demethylase K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E CJI96_0005411 SCF ubiquitin ligase complex subunit GRR1 K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E CJI96_0002464 DNA-binding SCF ubiquitin ligase subunit DIA2 K15068 DIA2; protein DIA2
E CJI96_0001832 SCF ubiquitin ligase complex subunit HRT3 K10295 FBXO9; F-box protein 9
E CJI96_0001188 hypothetical_protein K15071 RCY1; recyclin-1
E CJI96_0004659 SCF ubiquitin ligase complex subunit UFO1 K15073 UFO1; ubiquitin ligase complex F-box protein UFO1
C Cul2 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CJI96_0001913 elongin C K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CJI96_0004372 cullin CUL3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E CJI96_0003381 hypothetical_protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CJI96_0000277 hypothetical_protein K10609 CUL4; cullin 4
D Adoptor protein
D Target recognizing subunit (DCAF)
E CJI96_0003848 hypothetical_protein K10570 ERCC8; DNA excision repair protein ERCC-8
E CJI96_0002141 hypothetical_protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E CJI96_0002352 rRNA-processing protein SOF1 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CJI96_0000553 glucose-induced degradation complex subunit GID7 K22382 WDR26; WD repeat-containing protein 26
E CJI96_0004770 hypothetical_protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E CJI96_0001913 elongin C K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E CJI96_0000082 SCF ubiquitin ligase subunit SKP1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E CJI96_0004926 SCF ubiquitin ligase complex subunit HRT1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E CJI96_0005148 anaphase promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E CJI96_0002056 hypothetical_protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E CJI96_0005392 hypothetical_protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E CJI96_0000112 hypothetical_protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E CJI96_0001776 anaphase promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E CJI96_0004134 anaphase promoting complex subunit CDC27 K03350 APC3; anaphase-promoting complex subunit 3
E CJI96_0001744 anaphase promoting complex subunit CDC16 K03353 APC6; anaphase-promoting complex subunit 6
E CJI96_0003700 anaphase promoting complex subunit CDC23 K03355 APC8; anaphase-promoting complex subunit 8
E CJI96_0000069 hypothetical_protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D CJI96_0002956 DNA_repair_protein_rhp51 K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D CJI96_0001912 ubiquitin-protein ligase RMD5 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D CJI96_0002765 glucose-induced degradation complex subunit FYV10 K18624 MAEA; macrophage erythroblast attacher
D CJI96_0004938 hypothetical_protein K23335 GID4; glucose-induced degradation protein 4
D CJI96_0000553 glucose-induced degradation complex subunit GID7 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C STUB1-CHIC2 complex
C SLX5-SLX8 complex
D CJI96_0002931 SUMO-targeted ubiquitin ligase complex subunit SLX8 K22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
C Multi subunit type E3 associated proteins
D CJI96_0000216 hypothetical_protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D CJI96_0000084 hypothetical_protein K24350 UBXN7; UBX domain-containing protein 7
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D CJI96_0003497 hypothetical_protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D CJI96_0005385 hypothetical_protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D CJI96_0003484 hypothetical_protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D CJI96_0002857 ubiquitin-specific protease UBP14 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D CJI96_0002331 ubiquitin-specific protease UBP15 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D CJI96_0004774 ubiquitin-specific protease DOA4 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D CJI96_0001702 ubiquitin-specific protease UBP6 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D CJI96_0002338 ubiquitin-specific protease UBP8 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D CJI96_0003438 ubiquitin-specific protease UBP2 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D CJI96_0002767 ubiquitin-specific protease UBP1 K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D CJI96_0001877 hypothetical_protein K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D CJI96_0003596 hypothetical_protein K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D CJI96_0001142 hypothetical_protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D CJI96_0004565 hypothetical_protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D CJI96_0004783 26S_proteasome_regulatory_subunit_RPN11 K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C CJI96_0004242 hypothetical_protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C CJI96_0003497 hypothetical_protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C CJI96_0003313 hypothetical_protein K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D CJI96_0004075 hypothetical_protein K12176 COPS2; COP9 signalosome complex subunit 2
D CJI96_0002126 COP9 signalosome catalytic subunit RRI1 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D CJI96_0005408 hypothetical_protein K24364 CSN12; COP9 signalosome complex subunit 12
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 28, 2025