+E Ubiquitin system KO
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Ubiquitin System - Ceratina calcarata (carpenter bee)
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 108623231 polyubiquitin K08770 UBC; ubiquitin C
C 108623232 LOW QUALITY PROTEIN: polyubiquitin-like K08770 UBC; ubiquitin C
C 108624180 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 108626976 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 108622834 NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 108628378 uncharacterized protein LOC108628378 K02983 RP-S30e; small subunit ribosomal protein S30e
C 108625438 small ubiquitin-related modifier-like K12160 SUMO; small ubiquitin-related modifier
C 108629409 small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
C 108622225 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 108627733 autophagy protein 12-like K08336 ATG12; ubiquitin-like protein ATG12
C 108625176 ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 108629279 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 108627476 SUMO-activating enzyme subunit 1 isoform X2 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 108622902 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 108624376 NEDD8-activating enzyme E1 regulatory subunit isoform X1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 108622421 adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 108629356 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 108624960 ubiquitin-like modifier-activating enzyme atg7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 108625905 ubiquitin-conjugating enzyme E2-17 kDa isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 108633121 ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 108625657 ubiquitin-conjugating enzyme E2-17 kDa isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 108633157 ubiquitin-conjugating enzyme E2-24 kDa K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 108628554 ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 108625751 ubiquitin-conjugating enzyme E2 G2 isoform X1 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 108625931 ubiquitin-conjugating enzyme E2 J1-like isoform X2 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 108632794 ubiquitin-conjugating enzyme E2 J2-like K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 108625171 ubiquitin-conjugating enzyme E2-22 kDa K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 108631237 ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 108626861 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 108629436 (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O isoform X1 K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 108623155 transmembrane protein 231 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 108627302 ubiquitin-conjugating enzyme E2 Q2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 108624480 ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 108631801 ubiquitin-conjugating enzyme E2 S isoform X1 K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 108632133 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 108632398 ubiquitin-conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 108626750 baculoviral IAP repeat-containing protein 6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 108622874 SUMO-conjugating enzyme UBC9-B K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 108631001 NEDD8-conjugating enzyme UBE2F-like K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 108625825 NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 108630578 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 108624067 ubiquitin-like-conjugating enzyme ATG10 isoform X1 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 108632516 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 108631668 ubiquitin-protein ligase E3A isoform X2 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 108625300 ubiquitin-protein ligase E3B isoform X1 K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 108629885 ubiquitin-protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 108624455 uncharacterized protein LOC108624455 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 108631280 E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 108622392 E3 ubiquitin-protein ligase Su(dx) isoform X1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 108631992 E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 108630373 E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 108631603 E3 ubiquitin-protein ligase HUWE1 isoform X3 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 108623763 apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X2 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 108624884 E3 ubiquitin-protein ligase UBR5 isoform X3 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 108623397 uncharacterized protein LOC108623397 isoform X1 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 108629223 E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 108629284 probable E3 ubiquitin-protein ligase HERC4 isoform X3 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 108631271 E3 ubiquitin-protein ligase HECW2-like K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 108629892 E3 ubiquitin-protein ligase HECW2-like isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 108627322 NEDD4 family-interacting protein 1-like K25839 NDFIP; NEDD4 family-interacting protein
D 108627984 UPF0472 protein C16orf72 homolog K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
B U-box type E3
C 108628077 ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 108624037 ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 108629638 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 108624674 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 108625255 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 108624330 E3 ubiquitin-protein ligase RBBP6 isoform X2 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 108628779 RING finger protein 37 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 108625380 E3 ubiquitin-protein ligase Bre1 isoform X1 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 108629821 E3 ubiquitin-protein ligase CBL K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 108624525 E3 ubiquitin-protein ligase SIAH1-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D 108627467 E3 ubiquitin-protein ligase PDZRN3-B isoform X2 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 108630548 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MARCH8 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 108625515 E3 ubiquitin-protein ligase MARCH2-like K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 108625745 E3 ubiquitin-protein ligase MARCH3-like K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 108627312 E3 ubiquitin-protein ligase MARCH2-like K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 108627994 E3 ubiquitin-protein ligase MARCH3-like K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 108622041 E3 ubiquitin-protein ligase MARCH5-like isoform X1 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 108627722 E3 ubiquitin-protein ligase MARCH6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D 108632542 transcriptional repressor NF-X1 homolog K12236 NFX1; transcriptional repressor NF-X1
D 108622554 protein shuttle craft-like K12236 NFX1; transcriptional repressor NF-X1
D 108624322 NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 108623995 protein pellino isoform X1 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 108632576 peroxisome biogenesis factor 10-like K13346 PEX10; peroxin-10
D 108630037 peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 108628163 peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 108627940 E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 108623267 potential E3 ubiquitin-protein ligase ariadne-1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 108624851 potential E3 ubiquitin-protein ligase ariadne-2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 108630025 uncharacterized protein LOC108630025 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 108622317 E3 ubiquitin-protein ligase RNF14-like K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 108623840 E3 ubiquitin-protein ligase RNF19A-like K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 108622912 uncharacterized protein LOC108622912 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 108624666 E3 ubiquitin-protein ligase RNF34 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 108622951 probable E3 ubiquitin-protein ligase RNF144A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 108626104 uncharacterized protein LOC108626104 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 108628427 uncharacterized protein LOC108628427 isoform X1 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
D 108622235 TNF receptor-associated factor 6 isoform X1 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 108629617 brain tumor protein K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 108626999 tripartite motif-containing protein 2-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 108633109 E3 ubiquitin-protein ligase TRIM9 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 108629697 E3 ubiquitin-protein ligase TRIM33-like K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 108626348 E3 ubiquitin-protein ligase TRIM37-like isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 108626809 E3 ubiquitin-protein ligase TRIM71-like isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 108631741 E3 ubiquitin-protein ligase UBR2 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 108625400 E3 ubiquitin-protein ligase Ubr3 isoform X1 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 108625606 protein purity of essence isoform X1 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 108627615 putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 108623657 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 108622622 baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 108627165 baculoviral IAP repeat-containing protein 7-A-like K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 108625468 death-associated inhibitor of apoptosis 1-like K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 108622546 BRCA1-associated protein isoform X1 K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 108628902 breast cancer type 1 susceptibility protein homolog K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 108626416 E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 108628758 protein kinase 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 108623604 E3 ubiquitin-protein ligase DCST1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 108622798 protein deltex isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 108623221 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 108630858 E3 ubiquitin-protein ligase KCMF1-like isoform X1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 108628037 E3 ubiquitin-protein ligase LRSAM1-like isoform X1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 108633123 E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 108629321 RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 108625713 E3 ubiquitin-protein ligase MIB2 isoform X1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108623963 E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108626404 E3 ubiquitin-protein ligase mib1-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108623093 probable E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 108628582 mitochondrial E3 ubiquitin protein ligase 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 108625982 E3 ubiquitin-protein ligase MYCBP2-like isoform X1 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 108625172 E3 ubiquitin-protein ligase MYCBP2-like K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 108631964 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 108626622 protein neuralized isoform X1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 108629581 E3 ubiquitin-protein ligase RAD18-like K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 108628468 RING finger and CHY zinc finger domain-containing protein 1 isoform X1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 108632455 roquin-1 isoform X2 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 108625183 E3 ubiquitin-protein ligase RFWD3-like isoform X1 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 108632232 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 108625301 E3 ubiquitin-protein ligase RNF185-like K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 108623703 E3 ubiquitin-protein ligase rnf8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 108623171 RING finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 108627255 RING finger protein 11-like K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 108626131 E3 ubiquitin-protein ligase RNF167-like K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 108631623 E3 ubiquitin-protein ligase RNF25 isoform X1 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 108628746 RING finger protein 44-like isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 108625780 E3 ubiquitin-protein ligase NRDP1 isoform X1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 108624203 bromodomain-containing protein 4-like isoform X1 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 108627687 E3 ubiquitin-protein ligase RNF126 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 108631165 RING finger protein 121 isoform X1 K15698 RNF121_175; RING finger protein 121/175
D 108627618 E3 ubiquitin-protein ligase RNF123-like isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 108630621 protein TRC8 homolog K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 108628904 E3 ubiquitin-protein ligase RNF146-like K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 108630435 E3 ubiquitin-protein ligase RNF146-like isoform X1 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 108630943 probable E3 ubiquitin-protein ligase MGRN1 isoform X1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 113463999 E3 ubiquitin-protein ligase RNF180-like K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 108628382 E3 ubiquitin-protein ligase Rnf220-like isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 108630765 E3 ubiquitin-protein ligase Rnf220-like isoform X3 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 108625282 U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 108624440 E3 ubiquitin-protein ligase SH3RF3-like isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 108627176 E3 ubiquitin-protein ligase synoviolin A isoform X1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 108630768 E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 108627844 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 108625107 uncharacterized protein LOC108625107 K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 108630220 E3 ubiquitin-protein ligase TRAIP-like K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 108629733 E3 ubiquitin-protein ligase UHRF1-like K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 108627828 putative E3 ubiquitin-protein ligase UNKL isoform X2 K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 108629370 E3 ubiquitin-protein ligase ZNF598 isoform X1 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 108627406 E3 ubiquitin-protein ligase ZNRF2 isoform X1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
B Atypical E3
C 108627942 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 108625636 interferon regulatory factor 2-binding protein 2 isoform X1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 108627844 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 108622366 E3 SUMO-protein ligase RanBP2 isoform X2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 108627000 E3 SUMO-protein ligase PIAS2 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 108633069 E3 SUMO-protein ligase NSE2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 113464749 uncharacterized protein LOC113464749 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 108629303 zinc finger BED domain-containing protein 1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 108625868 zinc finger BED domain-containing protein 1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 108627290 E3 UFM1-protein ligase 1 homolog K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 108622992 DCN1-like protein 1 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 108623538 DCN1-like protein 3 isoform X1 K17823 DCUN1D3; DCN1-like protein 3
C 108622152 DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108627749 cullin-1 K03347 CUL1; cullin 1
D Adaptor protein
E 108624497 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 108630717 beta-TrCP isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 108628203 F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 108632377 F-box/WD repeat-containing protein 7 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 108631053 F-box/WD repeat-containing protein 9-like isoform X1 K10265 FBXW9; F-box and WD-40 domain protein 9
E 108629055 S-phase kinase-associated protein 2 isoform X1 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 108627078 F-box/LRR-repeat protein 20 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 108623264 F-box protein SKIP2-like K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 113464116 uncharacterized protein LOC113464116 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 108629909 F-box/LRR-repeat protein 3-like isoform X1 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 108623648 F-box/LRR-repeat protein 3-like K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 108623240 F-box/LRR-repeat protein 4 isoform X1 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 108628822 F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 108632116 dynein regulatory complex subunit 6-like isoform X1 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 108623065 jmjC domain-containing histone demethylation protein 1-like isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 108627137 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 108628500 F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 108630366 F-box only protein 44-like K10100 FBXO6; F-box protein 6
E 108626330 F-box only protein 7-like K10293 FBXO7; F-box protein 7
E 108626885 F-box only protein 9 K10295 FBXO9; F-box protein 9
E 108631031 F-box only protein 11 K10297 FBXO11; F-box protein 11
E 108622359 calponin homology domain-containing protein DDB_G0272472 isoform X1 K06084 LMO7; F-box protein 20
E 108626350 F-box only protein 21-like K10301 FBXO21; F-box protein 21
E 108624362 F-box only protein 22-like K10302 FBXO22; F-box protein 22
E 108629029 F-box only protein 32 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 108622527 F-box only protein 28 K10306 FBXO28; F-box protein 28
E 108628815 F-box only protein 28 isoform X3 K10306 FBXO28; F-box protein 28
E 108628461 F-box only protein 33 K10310 FBXO33; F-box protein 33
E 108623339 uncharacterized protein LOC108623339 isoform X2 K10314 FBXO39; F-box protein 39
E 108623633 F-box only protein 39-like K10314 FBXO39; F-box protein 39
E 108625337 F-box only protein 42 K10317 FBXO42; F-box protein 42
E 108622494 uncharacterized protein LOC108622494 K10318 FBXO43; F-box protein 43
E 108628286 F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
C Cul2 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108622237 cullin-2 isoform X1 K03870 CUL2; cullin 2
D Adoptor protein
E 108623743 elongin-C isoform X1 K03872 ELOC; elongin-C
E 108623719 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 108625034 von Hippel-Lindau disease tumor suppressor K03871 VHL; von Hippel-Lindau disease tumor supressor
E 108627117 leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 108632587 protein fem-1 homolog CG6966 isoform X1 K25805 FEM1A_C; protein fem-1 homolog A/C
E 108632223 protein fem-1 homolog B-like K10349 FEM1B; protein fem-1 homolog B
E 108630455 protein fem-1 homolog B isoform X1 K10349 FEM1B; protein fem-1 homolog B
E 108624290 amyloid protein-binding protein 2 isoform X1 K25806 APPBP2; amyloid protein-binding protein 2
E 108629002 kelch domain-containing protein 10 homolog K25809 KLHDC10; kelch domain-containing protein 10
E 108632384 protein zyg-11 homolog B-like isoform X1 K10350 ZYG11; Zyg-11 protein
E 108632758 protein zer-1 homolog isoform X1 K10350 ZYG11; Zyg-11 protein
E 108625917 zinc finger SWIM domain-containing protein 8 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108631227 cullin-3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 108625660 kelch-like protein 5 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 108622983 ring canal kelch homolog isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 108624400 LOW QUALITY PROTEIN: kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 108622465 LOW QUALITY PROTEIN: kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 108624963 kelch-like ECH-associated protein 1 isoform X1 K10456 KLHL19; kelch-like protein 19
E 108632928 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 108625375 actin-binding protein IPP K13956 IPP; actin-binding protein IPP
E 108624770 LOW QUALITY PROTEIN: BTB/POZ domain-containing protein 1-like K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 108629012 BTB/POZ domain-containing protein 6-B isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108629015 BTB/POZ domain-containing protein 3-like isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108631749 BTB/POZ domain-containing protein 6-B-like isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108628387 BTB/POZ domain-containing protein 6-A isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108624541 BTB/POZ domain-containing protein 7 isoform X1 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 108624983 protein germ cell-less K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 108629209 longitudinals lacking protein, isoforms N/O/W/X/Y-like isoform X2 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 108628891 transcription factor Ken 2-like isoform X1 K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
E 108624764 ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform X3 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 108628763 rho-related BTB domain-containing protein 1 isoform X5 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 108632192 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 108626505 BTB/POZ domain-containing protein kctd15-like isoform X2 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 108631214 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 108631032 BTB/POZ domain-containing protein KCTD3 isoform X2 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 108627294 BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 108629183 BTB/POZ domain-containing protein KCTD9 isoform X1 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 108628761 speckle-type POZ protein isoform X1 K10523 SPOP; speckle-type POZ protein
E 108625012 protein roadkill-like isoform X1 K10523 SPOP; speckle-type POZ protein
E 108628257 leucine-zipper-like transcriptional regulator 1 isoform X1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108625623 cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 108631887 DNA damage-binding protein 1 isoform X1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 108625820 DET1 homolog K10571 DET1; de-etiolated-1
E 108629781 DET1- and DDB1-associated protein 1 isoform X1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 108628784 protein cereblon isoform X1 K11793 CRBN; cereblon
E 108622458 protein mahjong K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 108623721 protein lethal(2)denticleless isoform X1 K11790 DTL; denticleless
E 108632127 DDB1- and CUL4-associated factor 5 isoform X1 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 108623619 DDB1- and CUL4-associated factor 6-like isoform X2 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 108630871 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 108623754 DDB1- and CUL4-associated factor 8-like isoform X3 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 108625971 WD and tetratricopeptide repeats protein 1-like isoform X1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 108630813 DDB1- and CUL4-associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 108627658 DDB1- and CUL4-associated factor 11 isoform X1 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 108623200 DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 108633074 DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 108632797 uncharacterized protein LOC108632797 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 108626901 PH-interacting protein isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 108626909 WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
E 108622368 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
E 108630321 RING-box protein 2 K10611 RBX2; RING-box protein 2
D Cullin
E 108624446 cullin-5 isoform X2 K10612 CUL5; cullin 5
D Adoptor protein
E 108623743 elongin-C isoform X1 K03872 ELOC; elongin-C
E 108623719 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 108622456 suppressor of cytokine signaling 5 isoform X2 K04698 SOCS5; suppressor of cytokine signaling 5
E 108628474 suppressor of cytokine signaling 5 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 108625749 uncharacterized protein LOC108625749 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 108624074 uncharacterized protein LOC108624074 isoform X2 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 108628601 protein gustavus isoform X2 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 108630949 SPRY domain-containing SOCS box protein 3-like K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 108631212 ras-related protein Rab-40B isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 108625173 RING finger and SPRY domain-containing protein 1-like K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 108624497 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 108631453 RING-box protein 1A isoform X3 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E 108633122 anaphase-promoting complex subunit 11 isoform X3 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 108626096 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 108630365 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 108627408 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 108628804 anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 108627254 cell division cycle protein 27 homolog isoform X1 K03350 APC3; anaphase-promoting complex subunit 3
E 108631671 anaphase-promoting complex subunit 4 isoform X1 K03351 APC4; anaphase-promoting complex subunit 4
E 108622760 anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
E 108628242 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 108630544 anaphase-promoting complex subunit 7 isoform X1 K03354 APC7; anaphase-promoting complex subunit 7
E 108622375 cell division cycle protein 23 homolog isoform X1 K03355 APC8; anaphase-promoting complex subunit 8
E 108626960 anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
E 108628744 anaphase-promoting complex subunit CDC26-like K03359 APC12; anaphase-promoting complex subunit 12
E 108630652 anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 108628548 anaphase-promoting complex subunit 15-like K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 108628902 breast cancer type 1 susceptibility protein homolog K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 108630653 breast cancer type 2 susceptibility protein homolog isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
D 108626377 lys-63-specific deubiquitinase BRCC36-like isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 108625472 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
D 108627052 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 108627618 E3 ubiquitin-protein ligase RNF123-like isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 108624271 ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 108630025 uncharacterized protein LOC108630025 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 108622912 uncharacterized protein LOC108622912 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 108630816 E3 ubiquitin-protein ligase RMND5A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 108632833 ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 108629478 armadillo repeat-containing protein 8-like K23336 ARMC8; armadillo repeat-containing protein 8
D 108629886 muskelin isoform X1 K23337 MKLN1; muskelin
D 108626424 E3 ubiquitin-protein transferase MAEA isoform X1 K18624 MAEA; macrophage erythroblast attacher
D 108631216 glucose-induced degradation protein 4 homolog isoform X1 K23335 GID4; glucose-induced degradation protein 4
D 108626963 glucose-induced degradation protein 8 homolog isoform X1 K23338 GID8; glucose-induced degradation protein 8
D 108622929 protein yippee-like 5 isoform X1 K23339 YPEL5; protein yippee-like 5
D 108626909 WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 108623657 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 108623729 transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 108625019 erlin-1-like K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 108631596 protein Lilipod isoform X1 K25215 LMBR1L; protein LMBR1L
D 108623657 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 108630874 cullin-associated NEDD8-dissociated protein 1 isoform X1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 108630547 COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 108632301 COMM domain-containing protein 3-like isoform X2 K22559 COMMD3; COMM domain containing 3
D 108632860 COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 108627349 COMM domain-containing protein 5-like K22561 COMMD5; COMM domain containing 5
D 108631139 COMM domain-containing protein 7-like K22563 COMMD7; COMM domain containing 7
D 108631963 COMM domain-containing protein 8-like K22564 COMMD8; COMM domain containing 8
D 108631394 COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 108626830 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 108629326 DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 108628473 glomulin isoform X1 K23345 GLMN; glomulin
D 108627212 UBX domain-containing protein 7 K24350 UBXN7; UBX domain-containing protein 7
D 108624980 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 108632418 protein lingerer isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 108630384 SH3 domain-containing protein Dlish K26546 Dlish; SH3 domain-containing protein Dlish
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 108624111 ubiquitin carboxyl-terminal hydrolase calypso isoform X1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 108626500 ubiquitin carboxyl-terminal hydrolase-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 108633149 ubiquitin carboxyl-terminal hydrolase-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 108622541 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 108624311 ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 108628532 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 1-like K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 108629898 hyphally regulated cell wall protein 3-like isoform X1 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 108627903 ubiquitin carboxyl-terminal hydrolase 3-like K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 108630977 ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 113465007 ubiquitin carboxyl-terminal hydrolase 7-like K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108625528 ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108632904 ubiquitin carboxyl-terminal hydrolase 8-like isoform X1 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 108631998 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 108623003 ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 108630417 ubiquitin carboxyl-terminal hydrolase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 108628445 ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 108629589 ubiquitin carboxyl-terminal hydrolase 16 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 108623401 ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 108622279 ubiquitin carboxyl-terminal hydrolase 22 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 108622799 ubiquitin carboxyl-terminal hydrolase 30 homolog K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 108629514 ubiquitin carboxyl-terminal hydrolase 31-like K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 108624645 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase puf K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 108628519 ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 108628379 ubiquitin carboxyl-terminal hydrolase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 108632941 ubiquitin carboxyl-terminal hydrolase 47 isoform X2 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 108627912 ubiquitin carboxyl-terminal hydrolase 48-like K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
C OTU
D 108625050 ubiquitin thioesterase otubain-like K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 108622249 OTU domain-containing protein 5-B isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 108622105 deubiquitinase OTUD6B isoform X1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 108624467 OTU domain-containing protein 7B-like K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 108626192 ubiquitin thioesterase trabid K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 108632317 ataxin-3-like K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 108627028 josephin-2 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 108623395 ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 108623904 inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 108626377 lys-63-specific deubiquitinase BRCC36-like isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 108631128 uncharacterized protein LOC108631128 K24173 MPND; MPN domain-containing protein
D 108631125 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 108626601 STAM-binding protein isoform X1 K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 108623061 deubiquitinase DESI2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 108623060 deubiquitinase DESI2-like isoform X2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 108627789 zinc finger-containing ubiquitin peptidase 1-like isoform X1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 108623825 BRISC complex subunit FAM175B-like K20799 FAM175B; BRISC complex subunit Abro1
D 108623623 BRISC and BRCA1-A complex member 1-like K20776 BABAM; BRISC and BRCA1-A complex member 1
D 108626377 lys-63-specific deubiquitinase BRCC36-like isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 108625472 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 108628399 sentrin-specific protease 1-like K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 108628910 uncharacterized protein LOC108628910 isoform X2 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 108622761 sentrin-specific protease 8-like K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 108626500 ubiquitin carboxyl-terminal hydrolase-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 108633149 ubiquitin carboxyl-terminal hydrolase-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 108624283 uncharacterized protein LOC108624283 isoform X4 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D 108625656 COP9 signalosome complex subunit 1 isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 108624874 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 108621921 COP9 signalosome complex subunit 3-like K12177 COPS3; COP9 signalosome complex subunit 3
D 108631538 COP9 signalosome complex subunit 3-like K12177 COPS3; COP9 signalosome complex subunit 3
D 108625018 COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 108628960 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 108626133 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 108627060 COP9 signalosome complex subunit 7b isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 108631093 COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 27, 2024