+F Repair protein KO
#
DNA Repair and Recombination Proteins - Chrysoperla carnea
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 123303028 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 123297639 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 123299608 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 123300543 N-glycosylase/DNA lyase isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 123291978 DNA-(apurinic or apyrimidinic site) endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 123297456 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 123302838 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 123302842 LOW QUALITY PROTEIN: DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 123299319 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 123297945 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 123292937 DNA polymerase epsilon catalytic subunit 1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 123300595 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 123295781 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 123305806 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
F 123300365 DNA polymerase epsilon subunit C K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 123305888 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 123295742 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 123299294 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 123296170 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 123292907 DNA ligase 3 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 123292047 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 123298483 uncharacterized protein F21D5.5 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 123305113 poly [ADP-ribose] polymerase isoform X1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 123300389 UV excision repair protein RAD23 homolog B K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 123293855 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123298473 cullin-4B K10609 CUL4; cullin 4
F 123292286 DNA damage-binding protein 1 isoform X1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 123306033 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 123296821 DNA-directed RNA polymerase II subunit RPB2 isoform X1 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 123302555 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 123296771 DNA-directed RNA polymerase II subunit Rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 123298267 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 123305650 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 123295757 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 123292426 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 123300929 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 123295554 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 123295263 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 123298443 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 123293855 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123298473 cullin-4B K10609 CUL4; cullin 4
F 123292286 DNA damage-binding protein 1 isoform X1 K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F 123298666 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
D TFIIH complex
E 123290465 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 123293955 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 123299105 general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 123296315 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 123305304 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 123300045 general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 123299816 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 123298234 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 123300568 cyclin-H K06634 CCNH; cyclin H
E 123299332 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 123305254 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123295556 replication protein A 32 kDa subunit-B K10739 RFA2; replication factor A2
E 123301634 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 123295441 DNA repair protein complementing XP-A cells homolog isoform X1 K10847 XPA; DNA-repair protein complementing XP-A cells
E 123305644 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 123296332 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 123299294 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 123302744 cullin-3 K03869 CUL3; cullin 3
E 123300973 cullin-5 K10612 CUL5; cullin 5
E 123303421 elongin-C K03872 ELOC; elongin-C
E 123292144 elongin-B K03873 ELOB; elongin-B
E 123297631 transcription elongation factor B polypeptide 3-like K15076 ELOA; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 123301480 DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 123302197 DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 123300974 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 123297612 mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 123297456 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 123302838 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 123302842 LOW QUALITY PROTEIN: DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 123299319 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 123297945 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 123305254 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123295556 replication protein A 32 kDa subunit-B K10739 RFA2; replication factor A2
E 123301634 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 123293528 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 123296099 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 123290501 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 123294063 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E 123300280 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 123305888 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 123300904 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 123299294 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 123291081 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123299130 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
E 123295369 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 123300663 BRCA1-A complex subunit Abraxas 1-like K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 123305681 BRISC and BRCA1-A complex member 1-like K20776 BABAM; BRISC and BRCA1-A complex member 1
E 123295044 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
E 123295658 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
D BRCA1-C complex
E 123291081 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123299130 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E 123292240 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 123292240 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 123303073 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 123296002 DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3
E 123293750 DNA repair protein XRCC2-like K10879 XRCC2; DNA-repair protein XRCC2
E 123297305 DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 123298277 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 123306077 DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 123294908 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 123305872 Werner syndrome ATP-dependent helicase-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 123291551 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123295996 ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 123301445 ATP-dependent DNA helicase Q5-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 123291551 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123294916 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123297290 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123300250 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 123305254 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123295556 replication protein A 32 kDa subunit-B K10739 RFA2; replication factor A2
E 123301634 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 123299679 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 123296623 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 123292100 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 123293049 serine/threonine-protein phosphatase 4 regulatory subunit 4-like K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
D SMC5-SMC6 complex
E 123296234 structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 123299807 structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 123292654 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 123303706 melanoma-associated antigen B16-like K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 123294577 EP300-interacting inhibitor of differentiation 3-like isoform X1 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 123290832 EP300-interacting inhibitor of differentiation 3-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 123298806 crossover junction endonuclease EME1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 123299782 exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 123298253 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 123300277 structure-specific endonuclease subunit slx1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 123294901 flap endonuclease GEN K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 123297312 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 123292984 fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 123296236 uncharacterized protein LOC123296236 K23112 BRAT1; BRCA1-associated ATM activator 1
E 123299780 uncharacterized protein LOC123299780 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 123300938 zinc finger SWIM domain-containing protein 7-like K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 123290455 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 123292702 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 123292713 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 123304491 uncharacterized protein DDB_G0287625-like K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 123297499 Werner Syndrome-like exonuclease K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
E 123291081 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123299130 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 123291904 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
D Other NHEJ factors
E 123296869 protein artemis K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
E 123300544 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E 123296546 centromere protein S-like K11511 APITD1; centromere protein S
E 123297562 centromere protein X-like K15360 STRA13; centromere protein X
E 123291025 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 123291551 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123294916 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123297290 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123300250 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 123306052 Fanconi anemia group D2 protein homolog K10891 FANCD2; fanconi anemia group D2 protein
E 123298805 Fanconi anemia group I protein homolog K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
D Other FA pathway factors
E 123292240 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 123303073 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 123291582 WD repeat-containing protein 48 homolog K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 123291778 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 123295451 serine/threonine-protein phosphatase 6 regulatory subunit 3 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
D Ubiquitin ligases
E 123292373 E3 ubiquitin-protein ligase rnf8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 123292737 E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 123297785 telomerase Cajal body protein 1 homolog K23314 WRAP53; telomerase Cajal body protein 1
E 123294685 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 123291597 DNApol-eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 123292180 DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 123294027 LOW QUALITY PROTEIN: DNA repair protein Rev1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D 123302985 ubiquitin-conjugating enzyme E2 2-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 123306013 ubiquitin-conjugating enzyme E2 2-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 123292446 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 123297795 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 123302531 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 123290937 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 123305888 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 123303579 DNA-dependent metalloprotease SPRTN-like K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 123305079 DNA-dependent metalloprotease dvc-1-like K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 123295847 inner centromere protein A-like K26957 GCNA; germ cell nuclear acidic protein
D 123306111 dentin sialophosphoprotein-like K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 123300517 cell cycle checkpoint control protein RAD9A-like K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 123298476 checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D 123300772 cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 123293313 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 123296099 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 123290501 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 123294063 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D 123300280 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 123300772 cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 123305050 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 123299041 TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
C BAG6-UBL4A-GET4 complex
D 123300600 uncharacterized protein LOC123300600 K23388 UBL4; ubiquitin-like protein 4
D 123294590 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 123298863 serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 123300496 serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 123291117 serine/threonine-protein kinase grp isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 123291965 ovarian-specific serine/threonine-protein kinase Lok K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 123293371 M-phase inducer phosphatase-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 123302157 14-3-3 protein zeta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 123294738 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 123301798 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 123300020 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 123302346 plastin-2 K17336 PLS3; plastin-3
D 123291929 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 123294983 vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 123301270 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 123293320 abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 123292294 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 123306097 DNA polymerase theta-like K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
C Nucleases
D 123295380 uncharacterized protein LOC123295380 K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
D 123295947 uncharacterized protein LOC123295947 K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
C Helicases
D 123292185 helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D 123296724 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 123290464 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 123300641 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 123300036 pleiotropic regulator 1 isoform X1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 123294562 7,8-dihydro-8-oxoguanine triphosphatase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 123300234 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 123301396 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123301417 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123302813 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123300005 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123295515 ribonucleoside-diphosphate reductase large subunit isoform X1 K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 123298625 ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 123297639 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 123299608 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 123298350 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 123298350 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 123301396 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123301417 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123302813 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123300005 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024