+D	Chaperone	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Chaperones and Folding Catalysts - Clostridioides difficile 630</h2>
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A<b>Heat shock proteins</b>
B  HSP110
B  HSP100
C    CD630_20200 clpB; Chaperone protein	K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 
C    CD630_00260 clpC; class III stress response-related ATPase, AAA+ superfamily	K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC 
C    CD630_33040 clpX; ATP-dependent Clp protease ATP-binding subunit clpX	K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX 
B  HSP90
C    CD630_02730 htpG; Heat shock protein 90 (Heat shock protein HtpG)(High temperature protein G)	K04079 HSP90A; molecular chaperone HtpG 
B  HSP70 / DNAK
C    CD630_24610 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)	K04043 dnaK; molecular chaperone DnaK 
B  HSP60 / Chaperonin
C    CD630_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroEL protein)	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
B  HSP47
B  HSP40 / DNAJ
C    CD630_24600 dnaJ; Chaperone protein DnaJ	K03686 dnaJ; molecular chaperone DnaJ 
B  HSP33
C    CD630_32190 hslO; 33 kDa chaperonin (Heat shock protein 33 homolog) (HSP33)	K04083 hslO; molecular chaperone Hsp33 
B  HSP24
C    CD630_24620 grpE; Protein grpE (HSP-70 cofactor)	K03687 GRPE; molecular chaperone GrpE 
B  HSP20
B  HSP15
B  HSP10
C    CD630_01930 groS; 10 kDa chaperonin (Protein Cpn10) (GroES protein)	K04078 groES; chaperonin GroES 
B  GimC
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A<b>Other chaperones and cochaperones</b>
B  Calnexin / calreticulin
B  DegP / HtrA
B  AAA proteases
C    CD630_06840 putative ATP-dependent peptidase, M41 family	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
C    CD630_18280 ftsH1; Cell division protease FtsH1	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
C    CD630_35590 ftsH2; Cell division protease FtsH2	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
B  PapD
C    CD630_34740 atpA2; ATP synthase A chain (ATP synthase F0 sector subunit a)	K02108 ATPF0A; F-type H+-transporting ATPase subunit a 
B  SecB
B  Sti1 / p60
B  Cdc37 / p50
B  BAG
B  Others
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A<b>Intramolecular chaperones</b>
B  Subtilisin family
C    CD630_20000 isp; Intracellular serine protease	K13275 isp; major intracellular serine protease [EC:3.4.21.-] 
B  Papain family
B  Other peptidases
B  Others
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A<b>Protein folding catalysts</b>
B  Peptidyl prolyl isomerase
C    Cyclophilin
D      CD630_03310 ppiB; Peptidyl-prolyl cis-trans isomerase B (PPIase B) (Rotamase B)	K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 
C    FKBP
D      CD630_35000 prsA1; Peptidylprolyl isomerase PrsA-like	K07533 prsA; foldase protein PrsA [EC:5.2.1.8] 
C    Parvulin
D      CD630_13570 putative peptidyl-prolyl isomerase	K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] 
B  Protein disulfide isomerase
C    CD630_16900 trxA; Thioredoxin	K03671 TXN; thioredoxin 
C    CD630_23550 trxA2; Thioredoxin 2 (Trx2)	K03671 TXN; thioredoxin 
C    CD630_30330 trxA1; Thioredoxin	K03671 TXN; thioredoxin 
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#Last updated: April 3, 2025