+F Repair protein KO #

  DNA Repair and Recombination Proteins - Clostridioides difficile 630

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D CD630_06010 ogt1; Methylated-DNA-[protein]-cysteine S-methyltransferase 1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D CD630_17700 ogt2; Methylated-DNA-[protein]-cysteine S-methyltransferase 2 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E CD630_24810 ung; Uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E CD630_14930 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E CD630_01910 putative DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] E CD630_05650 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D CD630_07050 putative hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D CD630_24030 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D CD630_06010 ogt1; Methylated-DNA-[protein]-cysteine S-methyltransferase 1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D CD630_17700 ogt2; Methylated-DNA-[protein]-cysteine S-methyltransferase 2 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E CD630_24810 ung; Uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E CD630_14930 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E CD630_05650 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E CD630_13410 exoA; Exodeoxyribonuclease K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E CD630_05600 nfo; Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D RecJ E CD630_27460 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E CD630_33090 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E CD630_11280 polA; DNA polymerase I (POLI) K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E CD630_34110 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A E CD630_34120 uvrB; Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E CD630_34100 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C E CD630_03280 pcrA; DNA helicase, UvrD/REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_04550 putative helicase, UvrD family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_07490 putative DNA helicase, UvrD/REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_10380 putative helicase, superfamily 1, UvrD-family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_11280 polA; DNA polymerase I (POLI) K02335 polA; DNA polymerase I [EC:2.7.7.7] E CD630_33090 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F CD630_00660 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F CD630_00670 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F CD630_00980 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F CD630_25871 rpoZ; DNA-directed RNA polymerase subunit omega (RNAP omega subunit) (Transcriptase subunit omega) (RNA polymerase omega subunit) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F CD630_35010 mfd; Transcription-repair coupling factor (TRCF ATP-dependent helicase mfd) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E CD630_19770 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS E CD630_07090 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 E CD630_21450 DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D Molecular matchmaker E CD630_19760 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases E CD630_12030 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E CD630_12040 xseB; Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E CD630_33960 dnaE; DNA polymerase III DnaE subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E CD630_13050 polC; PolIII (PolC) alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] E CD630_00020 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E CD630_24740 putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E CD630_35490 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E CD630_23940 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E CD630_00160 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E CD630_33090 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E CD630_03280 pcrA; DNA helicase, UvrD/REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_04550 putative helicase, UvrD family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_07490 putative DNA helicase, UvrD/REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_10380 putative helicase, superfamily 1, UvrD-family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CD630_29410 putative phage single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein E CD630_36620 ssb1; Single-stranded DNA-binding protein (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein E CD630_09350 putative S-adenosyl-L-methionine-dependent methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E CD630_01320 putative DNA helicase, RecD/TraA type K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E CD630_13280 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA E CD630_28060 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E CD630_28050 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E CD630_28070 ruvC; Crossover junction endodeoxyribonuclease RuvC (Holliday junction nuclease RuvC) (Holliday junction resolvase RuvC) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E CD630_25860 priA; Primosomal protein N' (ATP-dependent helicase priA) (Replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E CD630_10430 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50 E CD630_10420 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E CD630_13280 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA E CD630_00270 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms E CD630_00040 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF E CD630_25600 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E CD630_27460 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E CD630_24350 recO; DNA repair protein RecO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O) E CD630_00180 recR; DNA repair and recombination protein K06187 recR; recombination protein RecR E CD630_12090 recN; DNA repair protein RecN (Recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) E CD630_28060 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E CD630_28050 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E CD630_28070 ruvC; Crossover junction endodeoxyribonuclease RuvC (Holliday junction nuclease RuvC) (Holliday junction resolvase RuvC) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins E CD630_10410 addA; ATP-dependent nuclease subunit A (ATP-dependent helicase addA) K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] E CD630_10400 addB; ATP-dependent nuclease subunit B (ATP-dependent helicase addB), Superfamily 1 UvrD-family K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Other HR factor E CD630_29760 putative CRISPR-associated Cas1 family protein K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E CD630_10430 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50 E CD630_10420 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F CD630_00060 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F CD630_00050 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F CD630_12740 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F CD630_34960 hupA; Non-specific DNA-binding protein HBsu; signal recognition particle-like (SRP) component K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F CD630_27460 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F CD630_24350 recO; DNA repair protein RecO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O) F CD630_00180 recR; DNA repair and recombination protein K06187 recR; recombination protein RecR F CD630_33090 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F CD630_17010 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F CD630_34110 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A F CD630_34120 uvrB; Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D CD630_08990 dinB; DNA polymerase IV (Pol IV) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D CD630_13280 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA D CD630_19310 lexA; Transcriptional regulator, LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D CD630_12090 recN; DNA repair protein RecN (Recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) D CD630_29410 putative phage single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein D CD630_36620 ssb1; Single-stranded DNA-binding protein (Helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein D CD630_25250 recX; Regulatory protein RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D CD630_14310 putative helicase, DinG family K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C Modulation of nucleotide pools D CD630_07050 putative hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D CD630_24030 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D CD630_12610 putative ribonucleotide-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D CD630_29950 nrdE; Ribonucleoside-diphosphate reductase subunit alpha (Ribonucleotide reductase large subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D CD630_29940 nrdF; Ribonucleoside-diphosphate reductase subunit beta (Ribonucleotide reductase small subunit) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D CD630_13110 putative rna-binding protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025