+C Kinase KO
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Protein Kinases - Citrobacter freundii CFNIH1
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ASerine/threonine kinases: AGC group
B PKA family
B PKG family
B PKC family [OT]
B PKN family
B AUR family [OT]
B PDK1 family
B AKT/PKB family
B SGK family [OT]
B RSK family [OT]
B NDR family
B MAST family [OT]
B YANK family
B DMPK family [OT]
B GRK family [OT]
B Other
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
B CAMK2 family
B CAMKL family
B DAPK family
B DCAMKL family
B MAPKAPK family [OT]
B MLCK family
B PHK family
B PIM family [OT]
B PKD family
B PSK family
B RAD53 family
B Trio family [OT]
B TSSK family
B CDPK family
B CASK family
B Trbl family
B Other
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
B TTBK family
B VRK family
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ASerine/threonine kinases: CMGC group
B CDK family
B MAPK family [OT]
B GSK family [OT]
B CLK family
B CDKL family
B DYRK family [OT]
B RCK family [OT]
B SRPK family [OT]
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ASerine/threonine kinases: STE group
B STE7 family
B STE20 family
B STE11 family
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
B LISK family [OT]
B LRRK family
B MLK family
B RAF family [OT]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
B BUB family
B Bud32 family
B CAMKK family
B CDC7 family
B CK2 family
B Haspin family
B IKK family [OT]
B IRE family
B MOS family
B NAK family [OT]
B NEK family
B NKF1 family
B NKF2 family
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
B PEK family [OT]
B PLK family [OT]
B SCY1 family [OT]
B Slob family
B TBCK family
B TLK family
B TOPK family
B TTK family
B ULK family [OT]
B VPS15 family
B WEE family
B Wnk family
B ABC1 family
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
B PIKK family [OT]
B RIO family [OT]
B TAF1 family
B TIF1 family [OT]
B Other
B Bacterial family
C CFNIH1_17795 toxin HipA K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
B TGFBR2 family [OT]
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
B INSR family [OT]
B PDGFR family [OT]
B FGFR family [OT]
B VEGFR family [OT]
B MET family
B TRK family [OT]
B EPH family [OT]
B AXL family
B ALK family
B TIE family
B ROR family
B DDR family
B RET family
B ROS family
B CCK family
B RYK family
B MUSK family
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
B ACK family
B CSK family
B FAK family
B FES family
B JAK family [OT]
B SRC family
B TEC family
B SYK family
B Other
B Bacterial
C CFNIH1_21540 tyrosine protein kinase K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
C CFNIH1_00220 capsular biosynthesis protein K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
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AHistidine kinases
B OmpR family
C CFNIH1_12055 phoR; phosphate regulon sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C CFNIH1_15730 sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C CFNIH1_04680 envZ; osmolarity sensor protein K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C CFNIH1_17410 sensor protein RstB K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C CFNIH1_07150 cpxA; two-component sensor protein K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C CFNIH1_09710 histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C CFNIH1_21615 histidine kinase K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C CFNIH1_08235 sensor protein BasS/PmrB K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
C CFNIH1_01930 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C CFNIH1_02010 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C CFNIH1_12865 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C CFNIH1_02375 sensor protein QseC K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C CFNIH1_13580 sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C CFNIH1_03295 aerobic respiration control sensor protein ArcB K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
C CFNIH1_00240 histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
B NarL family
C CFNIH1_19455 nitrate/nitrite sensor protein NarX K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C CFNIH1_23745 nitrate/nitrite sensor protein NarQ K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
C CFNIH1_06460 histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
C CFNIH1_11890 histidine kinase K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
C CFNIH1_22705 hypothetical protein K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
C CFNIH1_22715 histidine kinase K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C CFNIH1_00860 histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C CFNIH1_00130 histidine kinase K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
B Spo family [OT]
B CitB family [OT]
C CFNIH1_13265 dpiB; histidine kinase K07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
C CFNIH1_08290 histidine kinase K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
B LytTR family [OT]
C CFNIH1_21885 histidine kinase K27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]
C CFNIH1_23340 membrane protein K27884 pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]
B NtrC family
C CFNIH1_06905 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C CFNIH1_07620 sensor protein ZraS K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C CFNIH1_22720 histidine kinase K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
C CFNIH1_24175 histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
C CFNIH1_23305 histidine kinase K08475 pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
B CheA family [OT]
C CFNIH1_20625 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
C CFNIH1_16915 histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 5, 2025
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Classification taken and modified from Hanks (2003)