+F Repair protein KO
#
DNA Repair and Recombination Proteins - Carassius gibelio (silver crucian carp)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 128031671 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 127958435 DNA oxidative demethylase ALKBH2-like K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 127946686 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 128013916 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like isoform X1 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 128030082 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 128025208 CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 127957093 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957388 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957438 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957828 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957830 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127991155 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127958008 cyclin-O K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 127946661 G/T mismatch-specific thymine DNA glycosylase-like K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 128013882 G/T mismatch-specific thymine DNA glycosylase-like isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 128013884 G/T mismatch-specific thymine DNA glycosylase isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 127953319 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 127968151 single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 128028586 single-strand selective monofunctional uracil DNA glycosylase-like K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 127963934 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127963172 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 128014191 endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 127971928 endonuclease 8-like 3 isoform X1 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 127957195 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 128019946 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 127956617 DNA-(apurinic or apyrimidinic site) endonuclease-like isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127969390 si:ch211-141o9.10; probable endonuclease 4 isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127978039 DNA-(apurinic or apyrimidinic site) endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127963658 DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 127952882 DNA polymerase delta catalytic subunit-like isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 127948092 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 127963446 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F 127941603 DNA polymerase delta subunit 3-like isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
F 127985933 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
F 127949206 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
F 128017220 DNA polymerase delta subunit 4-like isoform X1 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 127957707 DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 127933187 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 127976097 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 127958086 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 128006707 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 127968476 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
F 128022551 DNA polymerase epsilon subunit 4-like K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 127966820 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 128020938 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 127951106 zgc:110269; probable flap endonuclease 1 homolog K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127946346 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 128027050 probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 128013222 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127951483 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127934752 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 127962955 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 128019054 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 127975276 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 127985484 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 127957260 DNA ligase 3-like isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
E 127995629 DNA ligase 3-like K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 127976760 tyrosyl-DNA phosphodiesterase 1-like K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 128020466 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 127949016 aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127949704 LOW QUALITY PROTEIN: aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127972517 bifunctional polynucleotide phosphatase/kinase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 127973167 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127966512 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 128021008 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 128029543 high mobility group protein B1b K10802 HMGB1; high mobility group protein B1
E 127949609 DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 127983754 poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 127938729 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 127951314 poly [ADP-ribose] polymerase 2-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127964743 protein mono-ADP-ribosyltransferase PARP4-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127965192 LOW QUALITY PROTEIN: protein mono-ADP-ribosyltransferase PARP4-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127959487 protein mono-ADP-ribosyltransferase PARP3 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 128031794 poly [ADP-ribose] polymerase 2-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 128019683 protein mono-ADP-ribosyltransferase PARP4-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 128019684 protein mono-ADP-ribosyltransferase PARP4-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 128019685 protein mono-ADP-ribosyltransferase PARP4-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 128019686 protein mono-ADP-ribosyltransferase PARP4-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 127964226 DNA repair protein complementing XP-C cells K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 127942077 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 127942802 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 127949040 RAD23 homolog A, nucleotide excision repair protein a K10839 RAD23; UV excision repair protein RAD23
F 127986305 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 127987295 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 128020703 UV excision repair protein RAD23 homolog A-like K10839 RAD23; UV excision repair protein RAD23
F 127971949 uncharacterized protein LOC127971949 isoform X1 K10840 CETN2; centrin-2
F 128026940 uncharacterized protein LOC128026940 K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 127953577 RING-box protein 1-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127945830 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127971630 cullin-4B-like K10609 CUL4; cullin 4
F 127952709 cullin-4A K10609 CUL4; cullin 4
F 128027200 cullin-4B-like K10609 CUL4; cullin 4
F 127934571 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 127977319 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 127977554 DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 127968746 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 128025230 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 127971982 DNA-directed RNA polymerase II subunit RPB2-like K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 128027615 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 128014729 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 127950809 DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 128024443 DNA-directed RNA polymerase II subunit RPB4-like isoform X1 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 127943424 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127938332 DNA-directed RNA polymerases I, II, and III subunit RPABC1-like isoform X1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127987015 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127942714 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 127952619 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 127970920 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 128026966 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 127987001 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 127934494 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 127977867 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 127962146 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 128016355 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 127957275 DNA-directed RNA polymerase II subunit RPB11-a isoform X1 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 127995840 DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 127979165 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
F 127935679 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 127953577 RING-box protein 1-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127945830 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127971630 cullin-4B-like K10609 CUL4; cullin 4
F 127952709 cullin-4A K10609 CUL4; cullin 4
F 128027200 cullin-4B-like K10609 CUL4; cullin 4
F 127934571 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 127977319 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 128018828 DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 128026126 DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6
F 128026912 UV-stimulated scaffold protein A K23720 UVSSA; UV-stimulated scaffold protein A
F 127952847 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 127954793 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 127960162 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 128016161 general transcription and DNA repair factor IIH helicase subunit XPB-like isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 127972910 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 128029218 general transcription and DNA repair factor IIH helicase subunit XPD-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 127947461 general transcription factor IIH subunit 1-like K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 128014229 general transcription factor IIH subunit 1 isoform X1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 127958043 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 127957227 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 127979005 general transcription factor IIH subunit 4-like K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 127935641 general transcription factor IIH subunit 4-like K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 127983790 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 127938128 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 127938383 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 127957796 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 127998537 cyclin-dependent kinase 7-like K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 127957783 cyclin-H-like K06634 CCNH; cyclin H
E 127999398 cyclin-H-like K06634 CCNH; cyclin H
E 127970218 CDK-activating kinase assembly factor MAT1-like isoform X1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
E 128026109 CDK-activating kinase assembly factor MAT1-like K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 127972694 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 128029183 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127974906 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 127934873 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 127978646 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D Other NER factors
E 127976781 DNA repair protein complementing XP-A cells K10847 XPA; DNA-repair protein complementing XP-A cells
E 128019929 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 127968907 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 127973159 DNA excision repair protein ERCC-5 K10846 ERCC5; DNA excision repair protein ERCC-5
E 127951483 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127934752 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 128025095 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 127951177 cullin-3-B-like K03869 CUL3; cullin 3
E 127973095 cullin-3 K03869 CUL3; cullin 3
E 127935424 cullin-3-B-like K03869 CUL3; cullin 3
E 128028694 cullin-3-like isoform X1 K03869 CUL3; cullin 3
E 127941877 cullin-5-like isoform X1 K10612 CUL5; cullin 5
E 127972679 cullin-5-like isoform X1 K10612 CUL5; cullin 5
E 127985518 cullin-5 isoform X1 K10612 CUL5; cullin 5
E 128029323 cullin-5a K10612 CUL5; cullin 5
E 127945908 elongin-C-like K03872 ELOC; elongin-C
E 127950770 elongin-C-like K03872 ELOC; elongin-C
E 128029740 elongin C paralog b K03872 ELOC; elongin-C
E 128013305 elongin-C-like isoform X1 K03872 ELOC; elongin-C
E 127953686 elongin-B-like K03873 ELOB; elongin-B
E 127949326 elongin-B-like isoform X1 K03873 ELOB; elongin-B
E 128025687 elongin-B-like isoform X1 K03873 ELOB; elongin-B
E 127934869 elongin-A-like K15076 ELOA; elongin-A
E 127969880 elongin A, like isoform X1 K15076 ELOA; elongin-A
E 127978748 elongin-A K15076 ELOA; elongin-A
E 127941414 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127935088 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127978917 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127986036 ubiquitin-associated protein 2a isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 127969044 DNA mismatch repair protein Msh2-like isoform X1 K08735 MSH2; DNA mismatch repair protein MSH2
E 128025262 DNA mismatch repair protein Msh2-like K08735 MSH2; DNA mismatch repair protein MSH2
E 127958212 DNA mismatch repair protein Msh3 isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3
E 127969982 DNA mismatch repair protein Msh6 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 127965514 PMS1 protein homolog 1-like isoform X1 K10864 PMS1; DNA mismatch repair protein PMS1
E 127969902 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 128026573 LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh1-like K08734 MLH1; DNA mismatch repair protein MLH1
E 128025109 mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
E 128011337 DNA mismatch repair protein Mlh3 isoform X1 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 127952882 DNA polymerase delta catalytic subunit-like isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 127948092 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 127963446 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E 127941603 DNA polymerase delta subunit 3-like isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
E 127985933 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E 127949206 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E 128017220 DNA polymerase delta subunit 4-like isoform X1 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 127972694 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 128029183 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127974906 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 127934873 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 127978646 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 127956984 LOW QUALITY PROTEIN: replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 127949187 replication factor C subunit 1-like isoform X1 K10754 RFC1; replication factor C subunit 1
E 127942333 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 127967760 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 127986603 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 127966468 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 127958425 replication factor C subunit 5-like isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
E 128021062 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 128014022 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 127966820 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 128020938 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 127976498 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 128031406 exonuclease 1-like isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 127973167 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127966512 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 128021008 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 128029543 high mobility group protein B1b K10802 HMGB1; high mobility group protein B1
E 127951483 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127934752 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127961979 WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
E 128016979 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 127972536 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127942197 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127986041 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127974958 nibrin K10867 NBN; nibrin
D BRCA1-core complex
E 127965600 BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 127942309 BRCA1-A complex subunit Abraxas 1-like K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 127986671 BRCA1-A complex subunit Abraxas 1 K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 127941421 BRCA1-A complex subunit RAP80-like isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 127985508 BRCA1-A complex subunit RAP80 isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 128022563 BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 127975851 BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE
E 128031745 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
E 127942365 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E 127986499 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 127972924 Fanconi anemia group J protein isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 127946193 DNA topoisomerase 2-binding protein 1-A-like isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E 128013025 DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 128013247 DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 127972536 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127942197 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127986041 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127974958 nibrin K10867 NBN; nibrin
D BRCA complex
E 127972863 breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
E 127949743 partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
E 127984159 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127938789 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 127984159 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127938789 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
E 127983724 DNA repair protein RAD51 homolog 2 isoform X1 K10869 RAD51L1; RAD51-like protein 1
E 127966359 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 127957271 DNA repair protein RAD51 homolog 4 isoform X1 K10871 RAD51L3; RAD51-like protein 3
E 128013688 DNA repair protein XRCC2 isoform X1 K10879 XRCC2; DNA-repair protein XRCC2
E 127983455 DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 128014012 DNA repair protein RAD52 homolog isoform X1 K10873 RAD52; DNA repair and recombination protein RAD52
E 127942851 LOW QUALITY PROTEIN: RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1
E 127952690 RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E 127959779 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 127942984 helicase ARIP4-like isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 127987904 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 128030628 DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 127956536 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 127974858 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 127965968 bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 127934669 recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127979639 ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 127953125 ATP-dependent DNA helicase Q5 isoform X1 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 127934669 recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127953929 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127958672 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127962872 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 127956813 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
E 127946731 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
E 127977422 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E 127972694 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 128029183 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127974906 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 127934873 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 127978646 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 127952068 serine/threonine-protein phosphatase 4 catalytic subunit B-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127948471 serine/threonine-protein phosphatase 4 catalytic subunit B-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 128025070 serine/threonine-protein phosphatase 4 catalytic subunit B K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127946002 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127959220 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 128015928 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 128012973 serine/threonine-protein phosphatase 4 regulatory subunit 1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127963949 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127944664 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127959303 serine/threonine-protein phosphatase 4 regulatory subunit 2-B K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 128015856 serine/threonine-protein phosphatase 4 regulatory subunit 2-B-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 128011822 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127938748 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127970130 serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127984508 serine/threonine-protein phosphatase 4 regulatory subunit 3 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127984123 serine/threonine-protein phosphatase 4 regulatory subunit 4-like K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
E 127938795 serine/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 127968385 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 128022082 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 128031333 AP-5 complex subunit mu-1-like K19023 AP5M1; AP-5 complex subunit mu-1
E 127970392 AP-5 complex subunit sigma-1-like K19024 AP5S1; AP-5 complex subunit sigma-1
E 128026372 AP-5 complex subunit sigma-1-like K19024 AP5S1; AP-5 complex subunit sigma-1
E 127952092 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
E 127953197 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 127966294 structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 127951559 structural maintenance of chromosomes protein 6-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 127951560 structural maintenance of chromosomes protein 6-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 127933271 structural maintenance of chromosomes protein 6 isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 127976324 structural maintenance of chromosomes protein 6-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 127938916 protein LRATD1-like K22805 FAM84A; protein FAM84A
E 127984504 protein LRATD1-like K22805 FAM84A; protein FAM84A
E 127952290 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 127975388 E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 128030674 E3 SUMO-protein ligase NSE2-like isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 128012123 necdin-like 2 K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 127970374 non-structural maintenance of chromosomes element 4 homolog A K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 128026152 non-structural maintenance of chromosomes element 4 homolog A-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 127957785 SMC5-SMC6 complex localization factor protein 1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 127998986 SMC5-SMC6 complex localization factor protein 1-like K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 127970616 SMC5-SMC6 complex localization factor protein 2-like isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
E 128026390 SMC5-SMC6 complex localization factor protein 2 isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
D Other HR factors
E 128025204 crossover junction endonuclease EME1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 127976596 exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 128017234 crossover junction endonuclease MUS81 isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 127979388 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127945967 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127934068 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127934882 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 128027015 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 128021540 DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3
E 127969784 swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 127961720 structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 127943077 structure-specific endonuclease subunit SLX4-like K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 127988340 LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 127956234 flap endonuclease GEN homolog 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 128014017 spatacsin isoform X1 K19026 SPG11; spatacsin
E 127970101 zinc finger FYVE domain-containing protein 26-like isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 128026090 zinc finger FYVE domain-containing protein 26-like K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 127956199 RAD51-associated protein 1-like isoform X1 K20778 RAD51AP1; RAD51-associated protein 1
E 127977987 RAD51-associated protein 1-like isoform X1 K20778 RAD51AP1; RAD51-associated protein 1
E 127977581 mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1
E 127944583 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127967501 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127948407 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127948408 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127948411 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127948412 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127948413 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127949473 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127949476 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127949479 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127949480 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 128025046 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 128027910 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127969759 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 128026426 fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 128012877 DNA repair-scaffolding protein isoform X1 K22806 SPIDR; DNA repair-scaffolding protein
E 127979103 protein LRATD2a K22810 FAM84B; protein FAM84B
E 127974609 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 127935597 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 128031212 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 127949728 BRCA1-associated ATM activator 1-like K23112 BRAT1; BRCA1-associated ATM activator 1
E 127968588 cilia and flagella associated protein 410 K23456 CFAP410; cilla- and flagella-associated protein
E 127942432 hepatoma-derived growth factor-related protein 2 isoform X1 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127987960 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127988450 hepatoma-derived growth factor-related protein 2-like isoform X1 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127988568 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127988575 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127996706 zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 127952840 ATPase SWSAP1 K25771 SWSAP1; ATPase SWSAP1
E 127965878 BRCA2-interacting transcriptional repressor EMSY K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 128020917 BRCA2-interacting transcriptional repressor EMSY-like isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 127949657 heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein
E 127975359 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 128030192 LOW QUALITY PROTEIN: protein MMS22-like K26125 MMS22L; protein MMS22-like
E 127933148 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 128027406 biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 127971282 LOW QUALITY PROTEIN: biorientation of chromosomes in cell division protein 1-like 1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 127974885 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
E 127956631 PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner
E 127952659 homologous recombination OB-fold protein isoform X1 K27803 HROB; homologous recombination OB-fold protein
E 128031409 DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
E 127983465 DNA helicase MCM9 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 127969024 X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 127965476 X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 127962738 DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 127972536 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127942197 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127986041 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 127949640 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 127966042 DNA repair protein XRCC4-like K10886 XRCC4; DNA-repair protein XRCC4
E 128020593 DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4
E 127959662 non-homologous end-joining factor 1-like isoform X1 K10980 NHEJ1; non-homologous end-joining factor 1
E 128015351 non-homologous end-joining factor 1-like K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 127949609 DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 127965889 DNA-directed DNA/RNA polymerase mu K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 127969949 DNA nucleotidylexotransferase K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 128025839 DNA nucleotidylexotransferase-like isoform X1 K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 127962955 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 128019054 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 128020466 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 127949016 aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127949704 LOW QUALITY PROTEIN: aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127956396 protein artemis K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 127979455 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127974343 tyrosyl-DNA phosphodiesterase 2 isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127935185 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 128030481 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127962307 structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 128016438 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like isoform X1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 127951303 PWWP domain-containing DNA repair factor 3B-like isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 128031651 PWWP domain-containing DNA repair factor 3A-like K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 127957463 protein PAXX K25772 PAXX; protein PAXX
E 128010908 protein PAXX-like K25772 PAXX; protein PAXX
E 127946994 si:ch211-127m7.2; uncharacterized protein si:ch211-127m7.2 K26155 CYREN; cell cycle regulator of non-homologous end joining
E 127954238 jmjC domain-containing protein 8 K25792 JMJD8; jumonji domain-containing protein 8
E 127969769 shieldin complex subunit 2 K26129 SHLD2; shieldin complex subunit 2
E 128019078 zgc:101664; shieldin complex subunit 3 K26130 SHLD3; shieldin complex subunit 3
E 127971883 BEN domain-containing protein 4 K27845 BEND4; BEN domain-containing protein 4
E 128027509 BEN domain-containing protein 4-like K27845 BEND4; BEN domain-containing protein 4
C FA (Fanconi anemia) pathway
D FA core complex
E 127947385 Fanconi anemia group A protein isoform X1 K10888 FANCA; fanconi anemia group A protein
E 127963550 Fanconi anemia group C protein K10890 FANCC; fanconi anemia group C protein
E 127963016 Fanconi anemia group E protein isoform X1 K10892 FANCE; fanconi anemia group E protein
E 127947144 Fanconi anemia group F protein K10893 FANCF; fanconi anemia group F protein
E 128001835 Fanconi anemia group G protein K10894 FANCG; fanconi anemia group G protein
E 127970630 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 127976790 Fanconi anemia group M protein isoform X1 K10896 FANCM; fanconi anemia group M protein
E 128014383 Fanconi anemia core complex-associated protein 24 K10898 FAAP24; fanconi anemia-associated protein
E 127969295 LOW QUALITY PROTEIN: Fanconi anemia core complex-associated protein 100-like K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
E 128025299 Fanconi anemia core complex-associated protein 100 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
D FA core complex binding factors
E 127944203 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 127972144 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 127946672 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 127959008 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 128015692 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 128011473 hairy-related 9 K06054 HES1; hairy and enhancer of split 1
E 127959245 centromere protein S K11511 APITD1; centromere protein S
E 127953174 centromere protein X K15360 STRA13; centromere protein X
E 127944361 ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 127934669 recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127953929 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127958672 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127962872 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 127956813 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
E 127946731 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
E 127977422 recQ-mediated genome instability protein 2-like K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E 127959483 Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein
E 128014224 Fanconi anemia group I protein isoform X1 K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 127972863 breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
E 127972924 Fanconi anemia group J protein isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 127949743 partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
D Other FA pathway factors
E 127934277 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 127977862 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 127984159 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127938789 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
E 127966359 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 128013166 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 127959229 ubiquitin carboxyl-terminal hydrolase 1-like K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 128015632 ubiquitin carboxyl-terminal hydrolase 1-like K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 127946328 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 127935962 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 127950551 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 128013421 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 127957384 serine/threonine-protein phosphatase 6 catalytic subunit-like K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 128007544 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 127974153 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127956918 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127934373 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127977244 serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127947055 serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 128013734 serine/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 127979420 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127974911 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127935283 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 128030822 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127965604 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 128019918 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 127945121 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 127967974 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 128011834 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 127984063 E3 ubiquitin-protein ligase rnf8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 127938825 E3 ubiquitin-protein ligase rnf8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 127972738 E3 ubiquitin-protein ligase rnf168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 127972538 E3 ubiquitin-protein ligase RNF169-like K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 128028698 E3 ubiquitin-protein ligase RNF169-like K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 127959382 E3 ubiquitin-protein ligase HERC2-like isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
E 128015711 E3 ubiquitin-protein ligase HERC2-like K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 127962672 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
E 128017197 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
E 127958068 taperin-like K24164 TPRN; taperin
E 127958680 taperin-like K24164 TPRN; taperin
E 127958685 taperin-like K24164 TPRN; taperin
E 127989405 taperin K24164 TPRN; taperin
E 127966858 WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 127961979 WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
E 128016979 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 127969647 DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 128013318 DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 127957106 DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 127999655 DNA polymerase kappa-like K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 127965396 DNA repair protein REV1-like K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
D 128019721 DNA repair protein REV1-like K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 127983647 DNA polymerase zeta catalytic subunit isoform X1 K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
D 127962124 DNA polymerase nu-like isoform X1 K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 127971348 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127965230 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127949667 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 128015428 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 128027231 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 128019456 ubiquitin-conjugating enzyme E2 A-like isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127941768 ubiquitin-conjugating enzyme E2 B-like isoform X1 K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 127986521 ubiquitin-conjugating enzyme E2 B isoform X1 K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 127959493 E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 128015814 E3 ubiquitin-protein ligase RAD18-like isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 127950870 helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 127946250 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 127968124 ubiquitin-conjugating enzyme E2 variant 1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 128022656 ubiquitin-conjugating enzyme E2 variant 1 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 128013322 ubiquitin-conjugating enzyme E2 variant 2-like K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 127979237 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127956897 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127934716 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127977717 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 127966820 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 128020938 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 127974885 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
D 127956631 PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner
D 127983925 DNA-dependent metalloprotease SPRTN K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 127971947 germ cell nuclear acidic protein-like isoform X1 K26957 GCNA; germ cell nuclear acidic protein
D 128026939 germ cell nuclear acidic protein-like K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 127971395 cell cycle checkpoint control protein RAD9A-like K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 128027784 cell cycle checkpoint control protein RAD9A-like K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 127964124 cell cycle checkpoint control protein RAD9B K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 127945980 checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D 127972741 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D 128028595 cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 127958527 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 127942333 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 127967760 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 127986603 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 127966468 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 127958425 replication factor C subunit 5-like isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D 128021062 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 128014022 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 127972741 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D 128028595 cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 128022631 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 128016897 LOW QUALITY PROTEIN: TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 127935406 claspin-like isoform X1 K25773 CLSPN; claspin
D 127978516 claspin-like isoform X1 K25773 CLSPN; claspin
C Triple T complex
D 128013166 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 128011923 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 128018330 TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 127979433 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127972520 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127935372 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 128028953 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127962861 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 128018269 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 127968899 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
D 128024931 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 128027031 serine/threonine-protein kinase ATR-like K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 127942923 ATR-interacting protein K10905 ATRIP; ATR interacting protein
D 127972527 serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 127972656 cellular tumor antigen p53-like isoform X1 K04451 TP53; tumor protein p53
D 127957502 cellular tumor antigen p53 isoform X1 K04451 TP53; tumor protein p53
D 128017696 cellular tumor antigen p53-like K04451 TP53; tumor protein p53
D 128011372 cellular tumor antigen p53-like isoform X1 K04451 TP53; tumor protein p53
D 127941762 serine/threonine-protein kinase Chk1-like K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 127985384 serine/threonine-protein kinase Chk1-like isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 127957325 serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 128014228 serine/threonine-protein kinase Chk2-like isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 127970606 M-phase inducer phosphatase 1-like isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 128026373 M-phase inducer phosphatase 1-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 127978952 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127983612 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127963284 14-3-3 protein beta/alpha-B-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127975083 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127975914 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127935427 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127959464 14-3-3 protein beta/alpha-A K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127938252 14-3-3 protein beta/alpha-1-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 128031762 14-3-3 protein zeta/delta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 128015970 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 128018328 14-3-3 protein beta/alpha-B K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 128030695 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127972515 14-3-3 protein gamma-B K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127966170 14-3-3 protein eta K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127957813 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 128021356 14-3-3 protein gamma-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 128014873 14-3-3 protein gamma-1-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 128029363 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127962037 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2 isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 127972666 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 128016433 14-3-3 protein epsilon-like K06630 YWHAE; 14-3-3 protein epsilon
D 128029202 14-3-3 protein epsilon-like K06630 YWHAE; 14-3-3 protein epsilon
D 127961917 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127947375 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 128014336 neuron navigator 2 isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 128017311 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127934382 wee1-like protein kinase 1-A isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127977150 wee1-like protein kinase 1-A K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127977323 wee1-like protein kinase 2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127962700 period circadian protein homolog 1-like isoform X1 K21944 PER1; period circadian protein 1
D 127966397 period circadian protein homolog 1a isoform X1 K21944 PER1; period circadian protein 1
D 128021242 period circadian protein homolog 1-like K21944 PER1; period circadian protein 1
D 128016658 period circadian protein homolog 1-like isoform X1 K21944 PER1; period circadian protein 1
D 127935330 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127950842 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127968624 period circadian protein homolog 3-like isoform X1 K21945 PER3; period circadian protein 3
D 128022069 period circadian protein homolog 3-like isoform X1 K21945 PER3; period circadian protein 3
D 127974497 mediator of DNA damage checkpoint protein 1-like isoform X1 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 128030731 mediator of DNA damage checkpoint protein 1-like K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 127970986 plastin-3-like K17336 PLS3; plastin-3
D 128026873 plastin-3 K17336 PLS3; plastin-3
D 127946642 apoptosis-enhancing nuclease-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 128014717 apoptosis-enhancing nuclease-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 127951236 serine/threonine-protein kinase PLK3-like K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 128030967 serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 127968225 serine/threonine-protein kinase Nek4-like K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 128022580 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127984228 serine/threonine-protein kinase Nek1 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 128020054 serine/threonine-protein kinase Nek5 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127974383 serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 128030456 serine/threonine-protein kinase Nek11-like isoform X1 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 128013634 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 127950344 KN motif and ankyrin repeat domain-containing protein 4-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127952545 KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127953101 KN motif and ankyrin repeat domain-containing protein 1-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127953302 KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127963965 KN motif and ankyrin repeat domain-containing protein 3-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127957929 KN motif and ankyrin repeat domain-containing protein 1-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127958071 KN motif and ankyrin repeat domain-containing protein 1b K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127959951 KN motif and ankyrin repeat domain-containing protein 4 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 128015635 KN motif and ankyrin repeat domain-containing protein 4-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 128025488 KN motif and ankyrin repeat domain-containing protein 4-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127999896 KN motif and ankyrin repeat domain-containing protein 1-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 128018186 KN motif and ankyrin repeat domain-containing protein 3-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 128006482 KN motif and ankyrin repeat domain-containing protein 1-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 128013605 charged multivesicular body protein 4c K24782 CHMP4C; charged multivesicular body protein 4C
D 127951341 vacuolar protein sorting-associated protein 4B-like isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127943257 vacuolar protein sorting-associated protein 4B-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127946766 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 128014365 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 128025195 vacuolar protein sorting-associated protein 4B isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127987050 vacuolar protein sorting-associated protein 4B-like isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127933226 abscission/NoCut checkpoint regulator-like K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 127976531 abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 127942703 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
D 127988413 replication stress response regulator SDE2-like isoform X1 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 127985751 DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 127957889 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 128014672 myb-binding protein 1A-like protein isoform X1 K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 127948924 DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 127969135 DNA cross-link repair 1A protein isoform X1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D 127964266 5' exonuclease Apollo-like K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 128018663 5' exonuclease Apollo-like K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 127972417 exonuclease V isoform X1 K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 128016251 endonuclease V-like isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 127943351 DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 127979058 uncharacterized protein LOC127979058 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
D 127979187 uncharacterized protein LOC127979187 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 127986648 helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 127963933 DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 127971083 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 128026928 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 127933488 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 127976152 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 127963615 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 127964105 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 128018923 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 127952731 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 127959317 nucleotide triphosphate diphosphatase NUDT15-like isoform X1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 127953544 oxidized purine nucleoside triphosphate hydrolase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 127963969 8-oxo-dGDP phosphatase NUDT18-like K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 128018334 8-oxo-dGDP phosphatase NUDT18-like isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 127977563 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 127942045 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 127986385 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 127935085 ribonucleoside-diphosphate reductase subunit M2-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127938948 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127978554 ribonucleoside-diphosphate reductase subunit M2 B isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127984438 ribonucleoside-diphosphate reductase subunit M2-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 128031671 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 128025208 CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 127957093 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957388 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957438 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957828 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127957830 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127991155 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127968151 single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 128028586 single-strand selective monofunctional uracil DNA glycosylase-like K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 127953319 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 127963934 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127957195 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 128019946 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 127956619 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
E 127978527 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 127956619 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
D 127978527 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 127959317 nucleotide triphosphate diphosphatase NUDT15-like isoform X1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 127977563 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024