+F Repair protein KO
#
DNA Repair and Recombination Proteins - Chitinophaga agri
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GWR21_29200 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D GWR21_14125 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E GWR21_28445 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E GWR21_14460 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E GWR21_20250 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GWR21_21370 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D GWR21_18350 S1/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D GWR21_14080 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_16215 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_18655 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_23185 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_01365 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_03320 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_06175 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_21485 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GWR21_29200 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D GWR21_26745 methylated-DNA--[protein]-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D GWR21_29190 helix-turn-helix domain-containing protein K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D GWR21_14125 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D GWR21_15255 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E GWR21_28445 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E GWR21_19840 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E GWR21_29195 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E GWR21_14460 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E GWR21_20250 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GWR21_06510 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E GWR21_11945 Fpg/Nei family DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E GWR21_11265 endonuclease K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E GWR21_21370 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E GWR21_20015 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E GWR21_06650 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E GWR21_03640 nfi; deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
E GWR21_11825 nfi; deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E GWR21_14260 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E GWR21_20910 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E GWR21_19175 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E GWR21_16580 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E GWR21_21595 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E GWR21_11285 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E GWR21_18345 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E GWR21_18025 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E GWR21_20045 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GWR21_20670 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GWR21_19175 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E GWR21_20910 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F GWR21_23985 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F GWR21_23990 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F GWR21_23620 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F GWR21_17695 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E GWR21_14720 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E GWR21_24905 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E GWR21_28235 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E GWR21_28240 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E GWR21_01965 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E GWR21_01970 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E GWR21_28680 DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E GWR21_19670 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E GWR21_15385 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E GWR21_15390 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E GWR21_13690 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E GWR21_01315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E GWR21_18710 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E GWR21_12085 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E GWR21_19940 DNA polymerase III subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E GWR21_26960 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E GWR21_08085 GIY-YIG nuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E GWR21_14660 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E GWR21_20910 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E GWR21_20045 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GWR21_20670 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GWR21_20245 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E GWR21_12190 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E GWR21_26150 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E GWR21_26145 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E GWR21_26140 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E GWR21_19835 recA; recombinase RecA K03553 recA; recombination protein RecA
E GWR21_14060 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E GWR21_21810 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GWR21_21770 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E GWR21_12325 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E GWR21_00585 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E GWR21_00590 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E GWR21_19835 recA; recombinase RecA K03553 recA; recombination protein RecA
E GWR21_19955 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E GWR21_07885 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E GWR21_13905 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E GWR21_17140 AAA family ATPase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E GWR21_14260 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E GWR21_17950 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E GWR21_20035 recR; recombination protein RecR K06187 recR; recombination protein RecR
E GWR21_13790 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E GWR21_14060 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E GWR21_21810 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GWR21_21770 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E GWR21_00585 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E GWR21_00590 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E GWR21_21880 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E GWR21_20545 Ku protein K10979 ku; DNA end-binding protein Ku
E GWR21_20550 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E GWR21_11570 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F GWR21_07835 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F GWR21_15900 hypothetical protein K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F GWR21_17665 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F GWR21_20535 DNA topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F GWR21_25180 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F GWR21_20005 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F GWR21_20255 integration host factor subunit beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F GWR21_14260 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F GWR21_17950 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F GWR21_20035 recR; recombination protein RecR K06187 recR; recombination protein RecR
F GWR21_20910 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F GWR21_19450 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GWR21_21860 RecQ family ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GWR21_16580 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F GWR21_21595 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F GWR21_11285 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F GWR21_18345 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D GWR21_13685 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D GWR21_15260 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D GWR21_17960 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D GWR21_19835 recA; recombinase RecA K03553 recA; recombination protein RecA
D GWR21_13790 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D GWR21_06630 Error-prone repair protein ImuA K14160 imuA; protein ImuA
D GWR21_06635 DNA polymerase Y family protein K14161 imuB; protein ImuB
D GWR21_06640 dnaE; DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D GWR21_20245 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D GWR21_12190 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D GWR21_20675 RecX family transcriptional regulator K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D GWR21_25660 DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
D GWR21_00650 hypothetical protein K02347 polX; DNA polymerase (family X)
C DNA helicases
D GWR21_13655 ligase-associated DNA damage response DEXH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D GWR21_02770 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D GWR21_14080 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_16215 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_18655 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_23185 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_01365 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_03320 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_06175 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GWR21_29220 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D GWR21_21485 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D GWR21_25320 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D GWR21_04615 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D GWR21_06590 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D GWR21_25325 ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D GWR21_06585 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D GWR21_07945 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024