+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Citrobacter sp. TSA-1
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ACRISPR-Cas system
B Universal Cas proteins
C HF677_004865 cas1e; type I-E CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
C HF677_004870 cas2; type I-E CRISPR-associated endoribonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
B Type I CRISPR-Cas system
C Type I signiture cas proteins
D HF677_004835 cas3; CRISPR-associated helicase/endonuclease Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
D HF677_004840 casA; type I-E CRISPR-associated protein Cse1/CasA K19123 casA; CRISPR system Cascade subunit CasA
D HF677_004845 casB; type I-E CRISPR-associated protein Cse2/CasB K19046 casB; CRISPR system Cascade subunit CasB
D HF677_004850 cas7e; type I-E CRISPR-associated protein Cas7/Cse4/CasC K19124 casC; CRISPR system Cascade subunit CasC
D HF677_004855 cas5e; type I-E CRISPR-associated protein Cas5/CasD K19125 casD; CRISPR system Cascade subunit CasD
D HF677_004860 cas6e; type I-E CRISPR-associated protein Cas6/Cse3/CasE K19126 casE; CRISPR system Cascade subunit CasE
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C HF677_009785 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C HF677_020515 hsdR; type I restriction-modification system endonuclease K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C HF677_009770 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C HF677_020505 4'-phosphopantetheinyl transferase K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C HF677_009765 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C HF677_020510 hsdM; type I restriction-modification system methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D HF677_001550 dam; adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D HF677_008780 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D HF677_002105 yhdJ; adenine-specific DNA-methyltransferase K07319 yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D HF677_024170 DNA methylase K07319 yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D HF677_007295 site-specific DNA-methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D HF677_005725 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D HF677_009545 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D HF677_014070 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D HF677_014100 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
B Type IV R-M system
C HF677_014020 HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HF677_020415 restriction endonuclease K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
D HF677_007305 Hok/Gef family protein K18920 hokA; protein HokA
C SymE-SymR
D HF677_000305 type I addiction module toxin, SymE family K19048 symE; toxic protein SymE
D HF677_005145 type I toxin-antitoxin system SymE family toxin K19048 symE; toxic protein SymE
D HF677_020390 symE; endoribonuclease SymE K19048 symE; toxic protein SymE
C Ldr-Rdl
D HF677_000920 type I toxin-antitoxin system toxin Ldr family protein K18862 ldrA_B_C_D; small toxic polypeptide LdrA/B/C/D
C TisB-IstR
D HF677_000140 tisB; type I toxin-antitoxin system toxin TisB K19148 tisB; small toxic protein TisB
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
C ChpB-ChpS
C YhaV-PrlF
C RelE/StbE-RelB/StbD
D HF677_024215 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE
D HF677_024210 type II toxin-antitoxin system Phd/YefM family antitoxin K18923 stbD; antitoxin StbD
C YafQ-dinJ
C YoeB-YefM
D HF677_023935 yoeB; type II toxin-antitoxin system mRNA interferase toxin YoeB K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D HF677_023940 yefM; YoeB-YefM toxin-antitoxin system antitoxin YefM K19159 yefM; antitoxin YefM
C HipA-HipB
C HicA-HicB
C YafO-YafN
C PspC-PspB
D HF677_011130 pspC; envelope stress response membrane protein PspC K03973 pspC; phage shock protein C
D HF677_011125 pspB; envelope stress response membrane protein PspB K03970 pspB; phage shock protein B
C CcdB-CcdA
C ParE-ParD
D HF677_023340 type II toxin-antitoxin system RelE/ParE family toxin K19092 parE1_3_4; toxin ParE1/3/4
D HF677_023345 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D HF677_023355 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
C Doc-Phd
C HigB-HigA
D HF677_022935 cytoplasmic protein K19166 higB; mRNA interferase HigB [EC:3.1.-.-]
D HF677_022940 helix-turn-helix domain-containing protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
C MqsR-MqsA
C VapC-VapB
D HF677_024235 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D HF677_024230 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18829 mvpT; antitoxin VapB
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
C BC_0920-BC_0921
C SpoIISA-SpoIISB
C Tse6-Tsi6
C Type II TA system related factors
D HF677_020620 YhcH/YjgK/YiaL family protein K19334 tabA; biofilm protein TabA
D HF677_015735 DUF1471 domain-containing protein K13650 mcbA; MqsR-controlled colanic acid and biofilm protein A
D HF677_014665 bssS; biofilm formation regulator BssS K12148 bssS; biofilm regulator BssS
D HF677_015590 bssR; biofilm formation regulator BssR K19688 bssR; biofilm regulator BssR
D HF677_014330 DUF1471 domain-containing protein K12151 bhsA; multiple stress resistance protein BhsA
D HF677_019440 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D HF677_002170 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D HF677_003325 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D HF677_003295 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D HF677_006990 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
D HF677_020420 toxin K18837 cbtA; cytoskeleton-binding toxin CbtA and related proteins
D HF677_020425 type IV toxin-antitoxin system YeeU family antitoxin K18838 cbeA; cytoskeleton bundling-enhancing protein CbeA and related proteins
C CptA-CptB
D HF677_004155 hypothetical protein K19168 cptA; toxin CptA
D HF677_004150 sdhE; FAD assembly factor SdhE K09159 cptB; antitoxin CptB
C AbiEii-AbiEi
B Type V TA system
C GhoT-GhoS
C Other GhoT/OrtT toxin family protein
D HF677_011580 GhoT/OrtT family toxin K28274 ortT; orphan toxin OrtT
B Type VI TA system
C SocB-SocA
B Type VII TA system
C Hha-TomB
D HF677_017560 hha; hemolysin expression modulator Hha K05839 hha; haemolysin expression modulating protein
D HF677_017555 tomB; Hha toxicity modulator TomB K19162 tomB; hha toxicity modulator TomB
C TglT-TakA
C HepT-MntA
B Type VIII TA system
C SdsR-RyeA
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ADNA phosphothiolation system
B Sulfur modification proteins
C HF677_006420 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 19, 2025