+F Repair protein KO
#
DNA Repair and Recombination Proteins - Citrobacter sp. TSA-1
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HF677_011280 ogt; methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HF677_016380 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E HF677_006150 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HF677_003825 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HF677_012370 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D HF677_019420 mutT; 8-oxo-dGTP diphosphatase MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HF677_000445 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HF677_011280 ogt; methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HF677_007985 ada; bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D HF677_016380 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D HF677_007990 alkB; DNA oxidative demethylase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E HF677_006150 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HF677_003095 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E HF677_008980 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E HF677_003825 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HF677_000850 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E HF677_000470 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E HF677_016330 nei; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E HF677_012370 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E HF677_013340 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E HF677_008320 nfo; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E HF677_022310 nfi; deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E HF677_004175 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E HF677_000415 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HF677_006945 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E HF677_023060 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E HF677_022000 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E HF677_015860 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E HF677_009740 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E HF677_013295 cho; excinuclease Cho K05984 cho; excinuclease Cho [EC:3.1.25.-]
E HF677_024500 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HF677_023060 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E HF677_000415 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HF677_006945 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F HF677_022380 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F HF677_022375 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F HF677_001940 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F HF677_000405 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F HF677_014320 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E HF677_004940 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E HF677_021090 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E HF677_004425 mutH; DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E HF677_009260 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E HF677_006535 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E HF677_017820 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E HF677_013745 exoX; exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E HF677_019020 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E HF677_000010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E HF677_020580 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E HF677_016655 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E HF677_014450 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E HF677_018860 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HF677_017510 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E HF677_020115 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E HF677_024125 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E HF677_013735 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E HF677_000415 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HF677_006945 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E HF677_024500 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HF677_021995 ssb1; single-stranded DNA-binding protein SSB1 K03111 ssb; single-strand DNA-binding protein
E HF677_001550 dam; adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E HF677_008780 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E HF677_009550 very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E HF677_004480 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E HF677_004470 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E HF677_004485 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E HF677_005240 recA; recombinase RecA K03553 recA; recombination protein RecA
E HF677_010125 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HF677_010130 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HF677_010120 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E HF677_005730 RusA family crossover junction endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E HF677_022655 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E HF677_020960 priB; primosomal replication protein N K02686 priB; primosomal replication protein N
E HF677_017525 priC; primosomal replication protein N'' K04067 priC; primosomal replication protein N''
E HF677_020185 dnaT; primosomal protein DnaT K02317 dnaT; DNA replication protein DnaT
E HF677_009260 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E HF677_017985 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E HF677_017980 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E HF677_005240 recA; recombinase RecA K03553 recA; recombination protein RecA
E HF677_020030 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E HF677_000015 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E HF677_000390 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E HF677_004175 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E HF677_006220 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E HF677_017500 recR; recombination protein RecR K06187 recR; recombination protein RecR
E HF677_005980 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E HF677_018000 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E HF677_010125 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HF677_010130 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HF677_010120 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E HF677_004865 cas1e; type I-E CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E HF677_008125 DEAD/DEAH box helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E HF677_017985 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E HF677_017980 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E HF677_020560 DUF853 domain-containing protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F HF677_007925 gyrA; DNA topoisomerase (ATP-hydrolyzing) subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F HF677_000020 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F HF677_010990 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F HF677_022300 hupA; DNA-binding protein HU-alpha K05787 hupA; DNA-binding protein HU-alpha
F HF677_017695 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F HF677_014170 hypothetical protein K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F HF677_004175 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F HF677_006220 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F HF677_017500 recR; recombination protein RecR K06187 recR; recombination protein RecR
F HF677_000415 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F HF677_006945 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F HF677_002110 fis; DNA-binding transcriptional regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F HF677_013145 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F HF677_015280 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F HF677_009260 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F HF677_024525 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F HF677_022000 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F HF677_015860 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F HF677_010820 hns; DNA-binding transcriptional regulator H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D HF677_018520 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D HF677_024185 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D HF677_005915 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D HF677_011415 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D HF677_024180 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D HF677_005910 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D HF677_011410 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D HF677_005240 recA; recombinase RecA K03553 recA; recombination protein RecA
D HF677_022065 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D HF677_005980 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D HF677_019620 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D HF677_021995 ssb1; single-stranded DNA-binding protein SSB1 K03111 ssb; single-strand DNA-binding protein
D HF677_014085 DinI-like family protein K12149 dinI; DNA-damage-inducible protein I
D HF677_014660 dinI; DNA damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D HF677_005245 recX; recombination regulator RecX K03565 recX; regulatory protein
D HF677_023715 Rpn family recombination-promoting nuclease/putative transposase K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D HF677_023790 Rpn family recombination-promoting nuclease/putative transposase K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D HF677_024330 rep; DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D HF677_015065 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D HF677_015770 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D HF677_010270 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D HF677_019420 mutT; 8-oxo-dGTP diphosphatase MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HF677_000445 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HF677_005360 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D HF677_007915 nrdA; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D HF677_005355 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D HF677_007910 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024