+D Chaperone KO
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Chaperones and Folding Catalysts - Ciona intestinalis (yellow sea squirt)
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AHeat shock proteins
B HSP110
C 100186888 hypoxia up-regulated protein 1-like isoform X2 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 100177016 caseinolytic peptidase B protein homolog K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 100177682 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 100176019 heat shock protein HSP 90-beta K04079 HSP90A; molecular chaperone HtpG
C 100187454 endoplasmin K09487 HSP90B; heat shock protein 90kDa beta
C 100176051 heat shock protein 75 kDa, mitochondrial-like K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 619232 hsp70; heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 100187210 heat shock cognate 71 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 100176824 heat shock 70 kDa protein 4L K09489 HSPA4; heat shock 70kDa protein 4
C 100186609 endoplasmic reticulum chaperone BiP-like K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 101242470 endoplasmic reticulum chaperone BiP K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 100175645 stress-70 protein, mitochondrial-like K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 100181523 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin K09492 MKKS; McKusick-Kaufman syndrome protein
C 100175456 T-complex protein 1 subunit alpha K09493 CCT1; T-complex protein 1 subunit alpha
C 100181431 T-complex protein 1 subunit beta-like K09494 CCT2; T-complex protein 1 subunit beta
C 100181285 T-complex protein 1 subunit gamma-like K09495 CCT3; T-complex protein 1 subunit gamma
C 100184746 T-complex protein 1 subunit gamma-like K09495 CCT3; T-complex protein 1 subunit gamma
C 100176488 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 100181478 T-complex protein 1 subunit epsilon-like K09497 CCT5; T-complex protein 1 subunit epsilon
C 100176724 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 100185811 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 100185233 T-complex protein 1 subunit theta-like K09500 CCT8; T-complex protein 1 subunit theta
C 100186337 heat shock protein 60A-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 100186653 dnaJ homolog subfamily A member 1-like K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 100179194 dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
C 100180605 dnaJ homolog subfamily A member 3, mitochondrial isoform X2 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 100169912 zf(u1like)-8; Zn-finger (U1-like)-8 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 100184632 dnaJ homolog subfamily B member 4-like K09511 DNAJB5; DnaJ homolog subfamily B member 5
C 100175344 dnaJ homolog subfamily B member 6 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 100183834 dnaJ homolog subfamily B member 9 K09515 DNAJB9; DnaJ homolog subfamily B member 9
C 100187478 dnaJ homolog subfamily B member 11-like K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 445757 hsp40; heat shock protein 40 K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 100183931 dnaJ homolog subfamily C member 1 isoform X1 K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 100179182 dnaJ homolog subfamily C member 2 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 100180800 dnaJ homolog subfamily C member 3 K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 104266622 uncharacterized protein LOC104266622 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 100183104 dnaJ homolog subfamily C member 4 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 100179098 dnaJ homolog subfamily C member 5 isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 100186685 dnaJ homolog subfamily C member 7-like K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 100183982 dnaJ homolog subfamily C member 8 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 100181094 dnaJ homolog subfamily C member 9 K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 100179175 dnaJ homolog subfamily C member 10 isoform X2 K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
C 100179306 dnaJ homolog subfamily C member 11 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 100176568 J domain-containing protein-like K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 100180759 dnaJ homolog subfamily C member 13 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 100176543 dnaJ homolog subfamily C member 16-like K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 100183726 dnaJ homolog subfamily C member 17 isoform X1 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 100185485 mitochondrial import inner membrane translocase subunit TIM14-like K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 100179323 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 100184763 dnaJ homolog subfamily C member 25 K19371 DNAJC25; DnaJ homolog subfamily C member 25
C 664715 rbj; Ras-associated protein Rap1 K19372 DNAJC27; DnaJ homolog subfamily C member 27
C 100182652 dnaJ homolog subfamily C member 27-like isoform X1 K19372 DNAJC27; DnaJ homolog subfamily C member 27
C 100177909 iron-sulfur cluster co-chaperone protein HscB, mitochondrial-like isoform X1 K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 100187058 grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
B HSP20
C 100177240 alpha-crystallin A chain-like K04455 HSPB1; heat shock protein beta-1
B HSP15
B HSP10
C 100183218 10 kDa heat shock protein, mitochondrial-like K04078 groES; chaperonin GroES
B GimC
C 100184088 prefoldin subunit 1-like K09548 PFDN1; prefoldin subunit 1
C 100177542 prefoldin subunit 2-like K09549 PFDN2; prefoldin subunit 2
C 100183648 prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 100182453 prefoldin subunit 5 K04797 pfdA; prefoldin alpha subunit
C 100179681 prefoldin subunit 6-like K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C 100177539 calnexin isoform X1 K08054 CANX; calnexin
C 100181856 calreticulin K08057 CALR; calreticulin
B DegP / HtrA
C 100182899 serine protease HTRA1-like K08784 HTRA1; HtrA serine peptidase 1 [EC:3.4.21.-]
B AAA proteases
C 100181644 paraplegin-like K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 100182433 AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 100181490 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 100185452 hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 100180287 uncharacterized protein LOC100180287 K09555 BAG1; BCL2-associated athanogene 1
C 100185325 BAG family molecular chaperone regulator 3 isoform X1 K09557 BAG3; BCL2-associated athanogene 3
B Others
C 100182212 putative protein FAM10A4 K09560 ST13; suppressor of tumorigenicity protein 13
C 100183417 STIP1 homology and U box-containing protein 1 isoform X1 K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 100187139 HSPB1-associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C 100178100 protein Hikeshi K23327 HIKESHI; protein Hikeshi
C 100182428 NF-kappa-B inhibitor zeta-like isoform X1 K14242 NFKBIZ; NF-kappa-B inhibitor zeta
C 100177896 NF-kappa-B inhibitor-like protein 1 K09256 NFKBIL1; NF-kappa-B inhibitor-like protein 1
C 100180792 cysteine and histidine-rich domain-containing protein 1-like K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 100180600 cartilage-associated protein K19606 CRTAP; cartilage-associated protein
C 445606 leprecan; leprecan protein K08134 P3H1; procollagen-proline 3-dioxygenase 1 [EC:1.14.11.7]
C 100187483 protein N-lysine methyltransferase METTL21A-like K21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]
C 100178474 methyltransferase-like protein 23 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 100179629 protein unc-45 homolog B K21991 UNC45; protein unc-45
C 100184874 protein canopy 4-like K22816 CNPY3_4; protein canopy 3/4
C 100185464 protein canopy homolog 3-like isoform X1 K22816 CNPY3_4; protein canopy 3/4
C 100175480 torsin-1A K22990 TOR1; torsin-1
C 100183108 torsin-1A-interacting protein 2-like K23001 TOR1AIP; torsin-1A-interacting protein
C 100185473 torsin-1A-interacting protein 2-like isoform X1 K23001 TOR1AIP; torsin-1A-interacting protein
C 100186802 tetratricopeptide repeat protein 1-like K24926 TTC1; tetratricopeptide repeat protein 1
C 100176694 tetratricopeptide repeat protein 4 K24927 TTC4; tetratricopeptide repeat protein 4
C 100185712 coiled-coil domain-containing protein 47-like K24962 CCDC47; PAT complex subunit CCDC47
C 100183715 protein Asterix K24963 WDR83OS; PAT complex subunit Asterix
C 100178272 LRP chaperone MESD-like K25366 MESD; LRP chaperone MESD
C 100176348 activator of 90 kDa heat shock protein ATPase homolog 1-like K26216 AHSA1; activator of Hsp90 ATPase protein 1
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AIntramolecular chaperones
B Subtilisin family
C 100177229 membrane-bound transcription factor site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 100175968 proprotein convertase subtilisin/kexin type 4-like isoform X2 K01349 FURIN; furin [EC:3.4.21.75]
C 113474034 furin-like isoform X1 K01349 FURIN; furin [EC:3.4.21.75]
C 100181292 cipc2; Neuroendocrine convertase 2-like K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 100182587 furin-like protease kpc-1 isoform X1 K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 100177755 proprotein convertase subtilisin/kexin type 7-like K08673 PCSK7; proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-]
C 100177474 tripeptidyl-peptidase 2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 100176002 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 104266675 dipeptidyl peptidase 1-like K01275 CTSC; cathepsin C [EC:3.4.14.1]
C 100179909 cathepsin L1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 100187119 cathepsin L1-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 100176092 cathepsin L1-like isoform X3 K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
C 100183589 lysosomal protective protein isoform X1 K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
C 100176903 lysosomal protective protein K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Others
C 100182564 uncharacterized protein LOC100182564 K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 100178428 beta-hexosaminidase subunit alpha K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 100177256 uncharacterized protein LOC100177256 K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 100187142 beta-hexosaminidase subunit alpha-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 104266271 uncharacterized protein LOC104266271 isoform X1 K01229 LCT; lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62]
C 104266451 LOW QUALITY PROTEIN: von Willebrand factor-like K03900 VWF; von Willebrand factor
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 100183452 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 104266516 peptidyl-prolyl cis-trans isomerase 5-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 100179348 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 113474384 peptidyl-prolyl cis-trans isomerase-like K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 100177752 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 101242267 peptidyl-prolyl cis-trans isomerase K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 100181997 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 100180164 peptidyl-prolyl cis-trans isomerase G-like isoform X1 K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 100182981 peptidyl-prolyl cis-trans isomerase CYP22-like K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 100180391 peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 100175542 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 100183897 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 100181001 peptidyl-prolyl cis-trans isomerase-like 4 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 100183566 problable inactive peptidyl-prolyl cis-trans isomerase-like 6 K12739 PPIL6; peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8]
D 100176911 peptidylprolyl isomerase domain and WD repeat-containing protein 1 K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 100179805 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 100177946 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 101242693 E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 100175378 FK506-binding protein 2 K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D 100176168 peptidyl-prolyl cis-trans isomerase FKBP3 K09570 FKBP3; FK506-binding protein 3 [EC:5.2.1.8]
D 100186069 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase FKBP4-like K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 100178843 inactive peptidyl-prolyl cis-trans isomerase FKBP6 K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 100179953 peptidyl-prolyl cis-trans isomerase FKBP8 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 100177617 peptidyl-prolyl cis-trans isomerase FKBP9 K09575 FKBP9_10; FK506-binding protein 9/10 [EC:5.2.1.8]
D 100182633 FK506-binding protein 2-like K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 100177303 FK506-binding protein 15-like isoform X2 K17478 FKBP15; FK506-binding protein 15
D 100176538 ribosomal RNA-processing protein 8 K17478 FKBP15; FK506-binding protein 15
C Parvulin
D 100186662 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4-like K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 100181030 thioredoxin-like K03671 TXN; thioredoxin
C 100183957 thioredoxin-2 K03671 TXN; thioredoxin
C 100180659 probable thioredoxin-2 K03671 TXN; thioredoxin
C 100186204 thioredoxin-2-like K03671 TXN; thioredoxin
C 100181245 glutaredoxin-like K03676 grxC; glutaredoxin 3
C 101242419 glutaredoxin-like K03676 grxC; glutaredoxin 3
C 101242987 monothiol glutaredoxin-S6-like K03676 grxC; glutaredoxin 3
C 100180195 glutaredoxin-C8 K03676 grxC; glutaredoxin 3
C 100182247 LOW QUALITY PROTEIN: glutaredoxin-related protein 5, mitochondrial-like K07390 grxD; monothiol glutaredoxin
C 100181404 uncharacterized protein LOC100181404 K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 100182315 protein disulfide-isomerase 2 isoform X5 K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 108950166 protein disulfide-isomerase 2-like K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 100179353 protein disulfide-isomerase A3 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 100184179 protein disulfide-isomerase A4-like isoform X1 K09582 PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]
C 100177333 protein disulfide-isomerase A5 K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C 100175296 protein disulfide-isomerase A6-like K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 100185741 thioredoxin domain-containing protein 5 K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 100185726 protein disulfide-isomerase TMX3-like isoform X1 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024