+E Messenger RNA Biogenesis KO
#
Messenger RNA Biogenesis - Chelonus insularis
%
!
AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 118070830 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 118065452 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118065604 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118066103 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118066736 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118066737 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118067054 mRNA-capping enzyme-like isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118069779 LOW QUALITY PROTEIN: mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118069792 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118069793 LOW QUALITY PROTEIN: mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118069851 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118069900 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118071350 mRNA-capping enzyme-like isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118073530 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118064162 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118064873 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118065309 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118065310 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118065311 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118065313 mRNA-capping enzyme-like K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 118068977 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 118073662 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1-like K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
D Cap binding complex
E 118067560 nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 118070724 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 118067568 cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 118074762 cleavage and polyadenylation specificity factor subunit CG7185 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 118068150 protein CLP1 homolog K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 118063892 cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 118070574 probable cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 118068065 cleavage and polyadenylation specificity factor 73 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 118067383 cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 118068197 uncharacterized protein LOC118068197 K15542 PFS2; polyadenylation factor subunit 2
E 118073895 WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 118065979 serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 118075127 serine/threonine-protein phosphatase alpha-2 isoform K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 118069444 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 118074144 cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 118069269 cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 118066185 protein suppressor of forked K14408 CSTF3; cleavage stimulation factor subunit 3
E 118069381 symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 118065636 small nuclear ribonucleoprotein-associated protein B K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 118071423 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 118065913 probable small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 118066641 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 118067167 probable small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 118074155 U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 118070574 probable cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 118068065 cleavage and polyadenylation specificity factor 73 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 118069269 cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 118069381 symplekin K06100 SYMPK; symplekin
D DRB sensitivity inducing factor (DSIF) complex
E 118072538 transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 118074685 transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 118072957 N6-adenosine-methyltransferase subunit METTL3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 118066926 N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 118071920 pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 118073637 RNA-binding protein spenito K13190 RBM15; RNA-binding protein 15
D Poly(A) addition factors
E 118065159 poly(A) polymerase type 3 isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 118069847 uncharacterized protein LOC118069847 isoform X1 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 118071948 DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 118074452 methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 118071028 terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 118069557 serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 118072980 RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 118069480 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 118075021 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 118073837 ATP-dependent RNA helicase WM6 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 118068079 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 118069363 histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 118073173 RNA-binding protein with serine-rich domain 1-like K14325 RNPS1; RNA-binding protein with serine-rich domain 1
D TREX complex
E 118064023 THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 118073450 THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 118065801 THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 118075021 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 118074309 THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
D TREX-2 complex
E 118065416 PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 118066192 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 118073475 transcription and mRNA export factor ENY2-like K11368 ENY2; enhancer of yellow 2 transcription factor
D Nuclear pore complex
E 118066778 mRNA export factor K14298 RAE1; mRNA export factor
E 118068053 protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 118065454 nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 118071688 nuclear pore complex protein Nup93-like K14309 NUP93; nuclear pore complex protein Nup93
E 118067633 nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 118071822 nuclear pore complex protein Nup160 homolog K14303 NUP160; nuclear pore complex protein Nup160
E 118067771 nucleoporin SEH1-A isoform X1 K14299 SEH1; nucleoporin SEH1
E 118069270 NTF2-related export protein K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 118067970 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 118066948 acidic leucine-rich nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 118063897 ELAV-like protein 1 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 118067133 FAS-associated factor 2-B K18726 FAF2; FAS-associated factor 2
E 118065233 transitional endoplasmic reticulum ATPase TER94 K13525 VCP; transitional endoplasmic reticulum ATPase
E 118069031 exportin-1 K14290 XPO1; exportin-1
E 118074900 exportin-7 isoform X1 K18460 XPO7; exportin-7
E 118074977 ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E 118066187 eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 118068859 eukaryotic translation initiation factor 4E-like isoform X1 K03259 EIF4E; translation initiation factor 4E
E 118074141 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 118072682 eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 118064276 eukaryotic translation initiation factor 4E-binding protein 1 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 118073516 synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 118074754 cytoplasmic FMR1-interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 118070626 cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 118073200 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 118065945 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E 118065707 polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 118068052 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 118074014 deformed epidermal autoregulatory factor 1 isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 118063699 malignant T-cell-amplified sequence 1 homolog isoform X1 K07575 MCTS; malignant T-cell-amplified sequence
E 118069466 density-regulated protein homolog K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E 118073960 partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 118067679 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 118066149 RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 118067156 RNA-binding protein Musashi homolog Rbp6 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 118069415 heterogeneous nuclear ribonucleoprotein 27C isoform X1 K14411 MSI; RNA-binding protein Musashi
E 118071676 HBS1-like protein K14416 HBS1; elongation factor 1 alpha-like protein
E 118074372 protein pelota K06965 PELO; protein pelota
E 118071994 polyadenylate-binding protein 2-B K14396 PABPN1; polyadenylate-binding protein 2
E 118072077 DEAD-box helicase Dbp80 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 118074103 pre-mRNA-splicing factor syf1 homolog K12867 SYF1; pre-mRNA-splicing factor SYF1
E 118063902 regulator of chromosome condensation-like isoform X1 K11493 RCC1; regulator of chromosome condensation
E 118074656 transcriptional activator protein Pur-beta isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
C Surveillance factors
D Surveillance complex
E 118067684 eukaryotic peptide chain release factor subunit 1 isoform X1 K03265 ETF1; peptide chain release factor subunit 1
E 118067159 eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 118070792 regulator of nonsense transcripts 1 homolog K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 118064991 regulator of nonsense transcripts 2-like K14327 UPF2; regulator of nonsense transcripts 2
D Protein phosphatase 2A
E 118070996 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 118064701 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 118070693 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 118069022 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 118068018 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 118068208 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 118069209 probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 118073621 GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 118069431 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 118072058 protein bicaudal D isoform X1 K18739 BICD; protein bicaudal D
D Factors that have mRNA localization signals
E 118068711 actin-5C K05692 ACTB_G1; actin beta/gamma 1
E 118067883 enhancer of split m7 protein-like K09090 HESN; hairy and enhancer of split, invertebrate
E 118067884 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
E 118074095 protein hairy K09090 HESN; hairy and enhancer of split, invertebrate
D Trans-acting binding proteins
E 118073315 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
E 118074215 elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 118069553 double-stranded RNA-binding protein Staufen homolog isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 118074475 polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 118065534 RNA-binding protein squid isoform X1 K03102 SQD; squid
E 118065143 RNA-binding protein squid-like K03102 SQD; squid
E 118070626 cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 118073516 synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 118074754 cytoplasmic FMR1-interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 118065191 poly(rC)-binding protein 2 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 118067104 Y-box factor homolog isoform X1 K09276 YBX1; Y-box-binding protein 1
E 118070844 sex-lethal homolog K18747 SXL; protein sex-lethal
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 118064839 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 118064603 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 118066187 eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 118068859 eukaryotic translation initiation factor 4E-like isoform X1 K03259 EIF4E; translation initiation factor 4E
E 118070792 regulator of nonsense transcripts 1 homolog K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 118073200 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 118069038 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 118069776 RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 118067104 Y-box factor homolog isoform X1 K09276 YBX1; Y-box-binding protein 1
E 118069416 LIM domain-containing protein jub K16682 AJUBA; LIM domain-containing protein
E 118066942 putative helicase mov-10-B.1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 118068874 transportin-1 K18752 TNPO1; transportin-1
E 118067679 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 118064164 cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 118064754 cAMP-dependent protein kinase catalytic subunit beta-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 118066269 ataxin-2 homolog K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 118070127 m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 118072406 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 118067994 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 118070901 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 118073838 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 118066710 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 118067670 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 118072292 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 118069163 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 118068433 kinesin light chain isoform X1 K10407 KLC; kinesin light chain
E 118069431 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 118065495 tubulin alpha chain-like isoform X1 K07374 TUBA; tubulin alpha
E 118066159 tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 118067713 tubulin alpha-1 chain K07374 TUBA; tubulin alpha
E 118065193 tubulin alpha-1 chain-like K07374 TUBA; tubulin alpha
E 118070626 cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 118071944 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 118072800 CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 118071291 CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 118069182 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 118066033 CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 118070637 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 118071905 PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 118072647 protein Tob1-like isoform X1 K14443 TOB; protein Tob/BTG
E 118065175 protein BTG2-like K14443 TOB; protein Tob/BTG
E 118066924 protein BTG1-like K14443 TOB; protein Tob/BTG
E 118068807 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 118065927 enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 118064991 regulator of nonsense transcripts 2-like K14327 UPF2; regulator of nonsense transcripts 2
E 118074127 RING finger protein nhl-1 isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 118072522 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
D Stress granule specific factors
E 118065690 nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 118067459 nucleolysin TIAR K13201 TIA1; nucleolysin TIA-1/TIAR
E 118065945 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E 118069553 double-stranded RNA-binding protein Staufen homolog isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 118073516 synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 118067185 eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 118063922 eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 118074141 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 118068079 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 118072682 eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 118067201 ribosomal protein S6 kinase alpha-3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 118070994 guanine nucleotide-binding protein subunit beta-like protein K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 118070827 histone deacetylase 6 isoform X1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 118070127 m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 118069038 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 118068807 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 118065927 enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
D Lsm complex
E 118072406 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 118067994 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 118070901 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 118073838 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 118066710 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 118067670 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 118072292 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 118069163 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 118064839 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 118066314 5'-3' exoribonuclease 2 homolog K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 118072178 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 118066412 probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 118066997 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 118072804 uncharacterized protein LOC118072804 K03679 RRP4; exosome complex component RRP4
E 118068683 exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 118074200 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 118065073 exosome complex exonuclease RRP42-like K12589 RRP42; exosome complex component RRP42
E 118065799 exosome complex component RRP43-like K12586 RRP43; exosome complex component RRP43
D Exosome cofactors
E 118065216 exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 118072514 M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 118071908 terminal nucleotidyltransferase 4B-like isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 118067033 exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 118068052 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 118063715 WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 118069182 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 118071944 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 118072800 CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 118071291 CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 118066033 CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 118067052 CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
D Pan complex
E 118070637 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 118071905 PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 118074080 ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 118072647 protein Tob1-like isoform X1 K14443 TOB; protein Tob/BTG
E 118065175 protein BTG2-like K14443 TOB; protein Tob/BTG
E 118066924 protein BTG1-like K14443 TOB; protein Tob/BTG
E 118072178 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 118066412 probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 118072175 protein Smaug homolog 1 K27396 SMG; protein Smaug
E 118065380 focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 118074202 ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 118067577 oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 118066681 alpha-enolase-like isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 118073234 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 118067395 polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 118066495 ATP-dependent 6-phosphofructokinase isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 118064401 heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
E 118072070 heat shock protein 60A-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 118072804 uncharacterized protein LOC118072804 K03679 RRP4; exosome complex component RRP4
E 118066997 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 118074200 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 118065073 exosome complex exonuclease RRP42-like K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024