+E Replication protein KO
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DNA Replication Proteins - Citrus sinensis (Valencia orange)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 102617445 origin of replication complex subunit 1B-like K02603 ORC1; origin recognition complex subunit 1
D 102629303 origin of replication complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
D 102628160 origin of replication complex subunit 3 isoform X1 K02605 ORC3; origin recognition complex subunit 3
D 102619263 origin of replication complex subunit 4 isoform X1 K02606 ORC4; origin recognition complex subunit 4
D 102606827 origin of replication complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 127898603 origin of replication complex subunit 5-like K02607 ORC5; origin recognition complex subunit 5
D 102619526 origin of replication complex subunit 6 K02608 ORC6; origin recognition complex subunit 6
D 102607248 CDT1-like protein B K10727 CDT1; chromatin licensing and DNA replication factor 1
D 102620564 CDT1-like protein B K10727 CDT1; chromatin licensing and DNA replication factor 1
D 102615076 cell division control protein 6 homolog B K02213 CDC6; cell division control protein 6
D 102630547 DNA replication licensing factor MCM2 isoform X1 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 102621522 DNA replication licensing factor MCM3 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 102619925 DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 102622245 DNA replication licensing factor MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 102615859 DNA replication licensing factor MCM6 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 102629070 DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 102630886 cyclin-A2-4 isoform X1 K06627 CCNA; cyclin-A
D 102630346 cyclin-A2-1 K06627 CCNA; cyclin-A
D 102616765 cyclin-A1-4-like isoform X1 K06627 CCNA; cyclin-A
D 102617267 cyclin-A1-1 K06627 CCNA; cyclin-A
D 102611949 putative cyclin-A3-1 K06627 CCNA; cyclin-A
D 102621044 putative cyclin-A3-1 isoform X1 K06627 CCNA; cyclin-A
D 107174342 cell division control protein 2 homolog K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 102611219 cell division control protein 2 homolog isoform X1 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 107175385 cell division control protein 2 homolog K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 102607913 cell division control protein 2 homolog isoform X2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 112498552 cell division control protein 2 homolog isoform X1 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 102630658 uncharacterized protein LOC102630658 isoform X1 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C GINS complex
D 102606680 uncharacterized protein LOC102606680 isoform X1 K10732 GINS1; GINS complex subunit 1
D 102607275 uncharacterized protein LOC102607275 isoform X1 K10732 GINS1; GINS complex subunit 1
D 102627011 DNA replication complex GINS protein PSF2 K10733 GINS2; GINS complex subunit 2
D 102606676 DNA replication complex GINS protein PSF3 K10734 GINS3; GINS complex subunit 3
D 102615271 DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 102622944 uncharacterized protein LOC102622944 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 102624568 BRCT domain-containing protein At4g02110 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 102618543 ATP-dependent DNA helicase Q-like 5 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 102608530 uncharacterized protein LOC102608530 K06628 CDC45; cell division control protein 45
D 102628058 probable DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 102623036 probable DNA helicase MCM9 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 102630884 uncharacterized protein LOC102630884 K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 102618566 DNA polymerase alpha catalytic subunit K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 102617108 uncharacterized protein LOC102617108 K02321 POLA2; DNA polymerase alpha subunit B
D 102613266 uncharacterized protein LOC102613266 isoform X1 K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 102620839 probable DNA primase large subunit isoform X2 K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 102608212 DNA polymerase epsilon catalytic subunit A-like isoform X1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 102610782 DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 102618948 DNA polymerase II subunit B4 isoform X1 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C DNA polymerase delta complex
D 102612202 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 102626465 DNA polymerase delta small subunit isoform X3 K02328 POLD2; DNA polymerase delta subunit 2
D 102608043 uncharacterized protein LOC102608043 K03504 POLD3; DNA polymerase delta subunit 3
D 102608934 uncharacterized protein LOC102608934 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
D 102611437 replication protein A 70 kDa DNA-binding subunit A isoform X1 K07466 RFA1; replication factor A1
D 102626079 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
D 102626798 replication protein A 70 kDa DNA-binding subunit B K07466 RFA1; replication factor A1
D 102610707 replication protein A 32 kDa subunit A K10739 RFA2; replication factor A2
D 102610567 replication protein A 32 kDa subunit B isoform X1 K10739 RFA2; replication factor A2
D 102619411 replication protein A 14 kDa subunit B K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 102623585 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 102616275 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 102617383 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 102625196 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 102612743 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 102615422 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 102609520 uncharacterized protein LOC102609520 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 102611600 ribonuclease H2 subunit A K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 102607898 uncharacterized protein LOC102607898 K10744 RNASEH2B; ribonuclease H2 subunit B
D 102623981 uncharacterized protein LOC102623981 K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 102627400 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 102608255 DNA replication ATP-dependent helicase/nuclease JHS1 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 102618340 flap endonuclease 1 isoform X3 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 102615179 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 102616157 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 102611082 uncharacterized protein LOC102611082 isoform X1 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 102628869 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 102625992 uncharacterized protein LOC102625992 K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 102616428 DNA (cytosine-5)-methyltransferase 1-like K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 102618592 DNA (cytosine-5)-methyltransferase CMT3-like K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 102617543 putative DNA (cytosine-5)-methyltransferase CMT1 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 102609368 DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 102607628 PWWP domain-containing protein 1-like isoform X1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
C Prevention of re-replication factors
D 102628098 cyclin-SDS isoform X2 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102621929 G2/mitotic-specific cyclin S13-7 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102623620 G2/mitotic-specific cyclin S13-7 isoform X1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102627493 G2/mitotic-specific cyclin-2-like K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102615702 cyclin-B2-4 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102607220 putative cyclin-B3-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102607074 G2/mitotic-specific cyclin S13-7 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 102618170 G2/mitotic-specific cyclin-2 K21777 CCNB; G2/mitotic-specific cyclin-B, other
C Telomere proteins
D Shelterin complex
E 102608364 uncharacterized protein LOC102608364 isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
E 102629296 CST complex subunit STN1 K23312 STN1; CST complex subunit STN1
E 102607923 CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 102625932 telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E 102619891 putative H/ACA ribonucleoprotein complex subunit 1-like protein 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 102610926 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 102608916 H/ACA ribonucleoprotein complex subunit 3-like protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 102608573 H/ACA ribonucleoprotein complex subunit 4 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 102625932 telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 102630807 uncharacterized protein LOC102630807 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 102621015 small nuclear ribonucleoprotein SmD1a K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 102610531 uncharacterized protein LOC102610531 isoform X1 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 102629583 uncharacterized protein LOC102629583 isoform X1 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 102614429 small nuclear ribonucleoprotein SmD3b K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 102623698 uncharacterized protein LOC102623698 K11097 SNRPE; small nuclear ribonucleoprotein E
E 102619789 uncharacterized protein LOC102619789 K11097 SNRPE; small nuclear ribonucleoprotein E
E 102609283 probable small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 102617205 probable small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 102616275 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 102617383 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 102625196 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 102612743 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 102615422 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 102609520 uncharacterized protein LOC102609520 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 102624634 double-strand break repair protein MRE11 isoform X2 K10865 MRE11; double-strand break repair protein MRE11
D 102616752 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 102614559 nibrin homolog K10867 NBN; nibrin
C Other termination factors
D 102620162 serine/threonine-protein kinase ATM isoform X5 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 102608985 ATP-dependent DNA helicase Q-like SIM isoform X4 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 102610752 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 102620027 ATP-dependent DNA helicase Q-like 3 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 102624221 DNA repair endonuclease UVH1 isoform X1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 102621976 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 102609012 poly [ADP-ribose] polymerase 2-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 102620309 LOW QUALITY PROTEIN: protein ADP-ribosyltransferase PARP3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 102625457 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 2-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 102612870 G-patch domain-containing protein 1 K11135 PINX1; Pin2-interacting protein X1
D 102618736 regulator of telomere elongation helicase 1 homolog isoform X2 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 102620559 uncharacterized protein LOC102620559 K11137 TELO2; telomere length regulation protein
D 102631101 transcription factor Pur-alpha 1 K21772 PURA; transcriptional activator protein Pur-alpha
D 102628189 uncharacterized protein LOC102628189 K23314 WRAP53; telomerase Cajal body protein 1
D 102619656 uncharacterized protein LOC102619656 K25059 SDE2; replication stress response regulator SDE2
D 127901093 uncharacterized protein LOC127901093 K25059 SDE2; replication stress response regulator SDE2
D 107176482 uncharacterized protein LOC107176482 K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 102630648 DNA topoisomerase 1 beta-like K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 102610705 DNA topoisomerase 2 isoform X2 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 102618169 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 102617834 DNA topoisomerase 3-beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 102620340 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
D Other elongation factors
E 102617268 DNA polymerase I B, chloroplastic/mitochondrial isoform X1 K02335 polA; DNA polymerase I [EC:2.7.7.7]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
D RFC (replication factor C)
D Other elongation factors
E 102608255 DNA replication ATP-dependent helicase/nuclease JHS1 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 102618340 flap endonuclease 1 isoform X3 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 102628869 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C 102623274 DNA gyrase subunit A, chloroplastic/mitochondrial isoform X1 K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C 102614049 DNA gyrase subunit B, chloroplastic/mitochondrial-like isoform X1 K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C 102615212 DNA topoisomerase 6 subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022