+E Replication protein KO #

  DNA Replication Proteins - Citrobacter sp. Y3

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AEukaryotic type B DNA Replication Initiation Factors C pre-RC (pre-replication complex) C CDK (cyclin dependent kinase) C DDK (Dbf-4 dependent kinase) C GINS complex C Other initiation factors B DNA Replication Elongation Factors C DNA polymerase alpha / primase complex C DNA polymerase epsilon complex C DNA polymerase delta complex C DNA polymerase gamma complex (mitochondrial) C RPA (replication protein A) C RFC (replication factor C) C RNase H D HAP28_06040 rnhA; (GenBank) ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4] C Other elongation factors B DNA Replication Termination Factors C DNA methylation enzymes D HAP28_09570 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D HAP28_13985 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D HAP28_15720 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D HAP28_24155 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] C Prevention of re-replication factors C Telomere proteins D Shelterin complex D TERB1-TERB2-MAJIN complex D CST complex (animals) D CST complex (yeast) D RIF proteins D SIR proteins C Telomerase complex (animals) D Dyskerin complex C Telomerase complex (fungi) D Sm core complex C ELG1-RFC complex C MRN complex C Other termination factors B DNA Topoisomerases # AProkaryotic type B DNA Replication Initiation Factors C Initiation factors (bacterial) D HAP28_23490 hupA; (GenBank) DNA-binding protein HU-alpha K05787 hupA; DNA-binding protein HU-alpha D HAP28_06845 hupB; (GenBank) DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta D HAP28_10995 ihfA; (GenBank) integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha D HAP28_09225 ihfB; (GenBank) integration host factor subunit beta K05788 ihfB; integration host factor subunit beta D HAP28_00005 dnaA; (GenBank) chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D HAP28_04185 dnaB; (GenBank) replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D HAP28_09545 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D HAP28_23135 dnaB; (GenBank) replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D HAP28_21450 dnaC; (GenBank) DNA replication protein DnaC K02315 dnaC; DNA replication protein DnaC D HAP28_03730 dnaG; (GenBank) DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D HAP28_04240 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HAP28_14185 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HAP28_23105 ssb1; (GenBank) single-stranded DNA-binding protein SSB1 K03111 ssb; single-strand DNA-binding protein D HAP28_25400 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein C Initiation factors (archaeal) B DNA Replication Elongation Factors C Elongation factors (bacterial) D DNA polymerase III holoenzyme E HAP28_05885 dnaE; (GenBank) DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E HAP28_00010 dnaN; (GenBank) DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E HAP28_21925 holC; (GenBank) DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] E HAP28_07800 holA; (GenBank) DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E HAP28_10360 holB; (GenBank) DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E HAP28_06045 dnaQ; (GenBank) DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E HAP28_07025 dnaX; (GenBank) DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] E HAP28_21365 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7] E HAP28_15100 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D RNase H E HAP28_06040 rnhA; (GenBank) ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4] E HAP28_05880 rnhB; (GenBank) ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Other elongation factors E HAP28_24560 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E HAP28_00620 ligB; (GenBank) NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E HAP28_18270 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C Elongation factors (archaeal) D B-family DNA polymerases D D-family DNA polymerases D RNase H E HAP28_06040 rnhA; (GenBank) ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4] E HAP28_05880 rnhB; (GenBank) ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D RFC (replication factor C) D Other elongation factors B DNA Replication Termination Factors C Terminus site-binding protein D HAP28_11575 tus; (GenBank) DNA replication terminus site-binding protein K10748 tus; DNA replication terminus site-binding protein D HAP28_14025 DNA replication protein K10748 tus; DNA replication terminus site-binding protein C DNA methylation enzymes D HAP28_02005 dam; (GenBank) adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D HAP28_24160 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] C Prevention of re-replication factors D HAP28_07995 seqA; (GenBank) replication initiation negative regulator SeqA K03645 seqA; negative modulator of initiation of replication D HAP28_18605 hda; (GenBank) DnaA inactivator Hda K10763 hda; DnaA-homolog protein B DNA Topoisomerases C HAP28_17020 gyrA; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] C HAP28_00020 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] C HAP28_03940 parC; (GenBank) DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] C HAP28_03905 parE; (GenBank) DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] C HAP28_12960 topA; (GenBank) type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C HAP28_04225 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1] C HAP28_10760 topB; (GenBank) DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1] ! #
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#Last updated: August 27, 2025