+F Repair protein KO
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DNA Repair and Recombination Proteins - Clostridium kluyveri DSM 555
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CKL_0119 ogt; Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CKL_3744 Predicted 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CKL_0461 Predicted 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CKL_3410 Hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CKL_1144 dut; Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CKL_0119 ogt; Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CKL_3767 Phage-related DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CKL_3806 Uracil DNA glycosylase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CKL_3744 Predicted 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CKL_3410 Hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CKL_1412 Hypothetical protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E CKL_2140 recJ; RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E CKL_3482 ligA1; LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CKL_0669 polA; PolA K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CKL_3571 uvrA; UvrA K03701 uvrA; excinuclease ABC subunit A
E CKL_3572 uvrB; UvrB K03702 uvrB; excinuclease ABC subunit B
E CKL_3566 uvrC; UvrC K03703 uvrC; excinuclease ABC subunit C
E CKL_1652 UvrABC-related protein, protein C K03703 uvrC; excinuclease ABC subunit C
E CKL_3484 pcrA; PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_1468 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_2529 Predicted helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_0604 Predicted ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_1765 Conserved hypothetical protein with LexA domain K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_0669 polA; PolA K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CKL_3482 ligA1; LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CKL_0216 rpoB; RpoB K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CKL_0217 rpoC; RpoC K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CKL_0252 rpoA; RpoA K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CKL_1366 Predicted DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CKL_0152 mfd; Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CKL_1574 mutS; MutS K03555 mutS; DNA mismatch repair protein MutS
E CKL_3183 MutS-related protein K07456 mutS2; DNA mismatch repair protein MutS2
E CKL_0555 MutS-related protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E CKL_1575 mutL; MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E CKL_1228 xseA; XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E CKL_1229 xseB; XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CKL_3560 dnaE; DnaE K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CKL_1426 polC; PolC K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E CKL_0002 dnaN; DnaN K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CKL_0893 Conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CKL_3793 DNA polymerase-related protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CKL_4034 DNA polymerase III, epsilon subunit related exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CKL_3827 dnaX; DnaX K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CKL_3482 ligA1; LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CKL_3484 pcrA; PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_1468 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_2529 Predicted helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_0604 Predicted ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_1765 Conserved hypothetical protein with LexA domain K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CKL_3909 ssb3; Ssb3 K03111 ssb; single-strand DNA-binding protein
E CKL_4013 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CKL_1147 ssb1; Ssb1 K03111 ssb; single-strand DNA-binding protein
E CKL_2314 Predicted DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_4048 predicted DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_1889 Hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_4008 hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_3897 Predicted DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_1987 Predicted DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CKL_3294 Predicted DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CKL_3670 Predicted exodeoxyribonuclease K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CKL_1445 recA; RecA K03553 recA; recombination protein RecA
E CKL_3145 ruvA; RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CKL_3144 ruvB; RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CKL_1368 Hypothetical protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CKL_0121 Predicted exonuclease, sbcC related K03546 sbcC; DNA repair protein SbcC/Rad50
E CKL_4015 SbcCD related DNA repair protein K03546 sbcC; DNA repair protein SbcC/Rad50
E CKL_0122 Predicted exonuclease, sbcD related K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E CKL_1445 recA; RecA K03553 recA; recombination protein RecA
E CKL_0196 radA; RadA K04485 radA; DNA repair protein RadA/Sms
E CKL_0004 recF; RecF K03629 recF; DNA replication and repair protein RecF
E CKL_1384 Hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CKL_2761 DNA helicase-related protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CKL_3659 Predicted transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CKL_2140 recJ; RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E CKL_0917 recO; RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E CKL_3825 recR; RecR K06187 recR; recombination protein RecR
E CKL_1235 recN; RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E CKL_3145 ruvA; RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CKL_3144 ruvB; RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E CKL_0706 Predicted ATP-dependent exonuclease K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E CKL_0996 addB; AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E CKL_2752 Conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E CKL_0121 Predicted exonuclease, sbcC related K03546 sbcC; DNA repair protein SbcC/Rad50
E CKL_4015 SbcCD related DNA repair protein K03546 sbcC; DNA repair protein SbcC/Rad50
E CKL_0122 Predicted exonuclease, sbcD related K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CKL_0007 gyrA1; GyrA1 K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CKL_0006 gyrB1; GyrB1 K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CKL_1415 Hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CKL_0157 hup; Hup K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CKL_0416 Phage-related protein K07455 recT; recombination protein RecT
F CKL_1895 Phage-related rekombinase protein K07455 recT; recombination protein RecT
F CKL_1992 Phage-related rekombinase protein K07455 recT; recombination protein RecT
F CKL_2140 recJ; RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F CKL_0917 recO; RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F CKL_3825 recR; RecR K06187 recR; recombination protein RecR
F CKL_3482 ligA1; LigA1 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F CKL_2379 recQ; RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CKL_3571 uvrA; UvrA K03701 uvrA; excinuclease ABC subunit A
F CKL_3572 uvrB; UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CKL_3439 dinB; DinB K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D CKL_1445 recA; RecA K03553 recA; recombination protein RecA
D CKL_1579 lexA; LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D CKL_1646 Transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D CKL_1235 recN; RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CKL_3909 ssb3; Ssb3 K03111 ssb; single-strand DNA-binding protein
D CKL_4013 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CKL_1147 ssb1; Ssb1 K03111 ssb; single-strand DNA-binding protein
D CKL_3329 Predicted regulatory protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CKL_1144 dut; Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D CKL_1433 Predicted hydrolase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024