+E Ubiquitin system KO
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Ubiquitin System - Colletotrichum lupini
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C CLUP02_00233 ubiquitin K08770 UBC; ubiquitin C
C CLUP02_12744 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C CLUP02_08643 40S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C CLUP02_00746 autophagy protein 8 K08341 GABARAP; GABA(A) receptor-associated protein
C CLUP02_16441 ubiquitin-like autophagy protein Apg12 K08336 ATG12; ubiquitin-like protein ATG12
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C CLUP02_17345 ubiquitin-activating enzyme E1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C CLUP02_03656 ThiF family protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C CLUP02_02174 ThiF family protein K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C CLUP02_05249 ThiF family protein K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C CLUP02_17376 ThiF family protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CLUP02_11747 ThiF family protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C CLUP02_10372 ubiquitin-like modifier-activating enzyme atg-7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C CLUP02_13957 ubiquitin-conjugating enzyme K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C CLUP02_07452 ubiquitin-conjugating enzyme E2-18 kDa K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C CLUP02_16439 ubiquitin-conjugating enzyme K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C CLUP02_08388 ubiquitin-conjugating enzyme K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C CLUP02_17151 ubiquitin-conjugating enzyme K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C CLUP02_09634 ubiquitin-conjugating enzyme K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C CLUP02_08543 ubiquitin-conjugating enzyme E2 35 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C CLUP02_08113 ubiquitin-conjugating enzyme K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C CLUP02_05337 ubiquitin-conjugating enzyme K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C CLUP02_05565 ubiquitin-conjugating enzyme K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
B UBL-conjugating enzymes
C CLUP02_10963 SUMO-conjugating enzyme ubc9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C CLUP02_14720 autophagy-like protein 3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C CLUP02_06099 uncharacterized protein K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
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AUbiquitin ligases (E3)
B HECT type E3
C CLUP02_16385 HECT-domain-containing protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C CLUP02_00285 HECT-domain-containing protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C CLUP02_10567 E3 ubiquitin-protein ligase HulA K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C CLUP02_01515 HECT-domain-containing protein K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C CLUP02_01178 HECT-domain-containing protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C CLUP02_01900 ubiquitin elongating factor core K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C CLUP02_18252 U-box domain-containing protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C CLUP02_03461 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C CLUP02_02390 uncharacterized protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D CLUP02_04057 BRE1 E3 ubiquitin ligase K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D CLUP02_04524 uncharacterized protein K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D CLUP02_05772 NF-X1 type zinc finger K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D CLUP02_05779 Pex2/Pex12 amino terminal region K13346 PEX10; peroxin-10
D CLUP02_14986 Pex2/Pex12 amino terminal region K13345 PEX12; peroxin-12
D CLUP02_13691 Pex2/Pex12 amino terminal region K06664 PEX2; peroxin-2
C RBR proteins
D CLUP02_06372 IBR domain-containing protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D CLUP02_08209 RWD domain-containing protein K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D CLUP02_18172 ubiquitin-conjugating enzyme K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D CLUP02_06096 uncharacterized protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CLUP02_10176 uncharacterized protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D CLUP02_00234 Zn-finger in ubiquitin-hydrolase K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D CLUP02_17381 E3 ubiquitin-protein ligase CCNB1IP1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D CLUP02_00216 general negative regulator of transcription subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D CLUP02_18064 uncharacterized protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D CLUP02_15477 DNA repair protein rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CLUP02_10336 uncharacterized protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D CLUP02_18014 ankyrin repeat protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D CLUP02_01168 SART-1 family protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D CLUP02_08294 SNF2 family domain-containing protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D CLUP02_15257 SNF2 family domain-containing protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CLUP02_10061 uncharacterized protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CLUP02_11563 zinc finger protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D CLUP02_12577 uncharacterized protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D CLUP02_08192 uncharacterized protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
B Atypical E3
C CLUP02_15035 RING-like domain-containing protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C CLUP02_03577 MIZ/SP-RING zinc finger K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C CLUP02_00275 uncharacterized protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C CLUP02_02472 uncharacterized protein K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CLUP02_14917 Cullin family protein K03347 CUL1; cullin 1
D Adaptor protein
E CLUP02_03302 Skp1 family protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E CLUP02_16065 WD domain-containing protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E CLUP02_04637 WD repeat domain-containing protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E CLUP02_04687 WD domain-containing protein K10259 MET30; F-box and WD-40 domain protein MET30
E CLUP02_03623 WD domain-containing protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CLUP02_11443 WD domain-containing protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CLUP02_03859 F-box domain-containing protein K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E CLUP02_13331 cyclic nucleotide-binding domain-containing protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E CLUP02_09531 F-box domain-containing protein K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E CLUP02_13624 F-box domain-containing protein K10295 FBXO9; F-box protein 9
E CLUP02_06235 F-box domain-containing protein K10301 FBXO21; F-box protein 21
E CLUP02_08293 exocyst complex component Sec10 K15071 RCY1; recyclin-1
C Cul2 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CLUP02_01422 Skp1 family protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CLUP02_11850 Cullin family protein K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E CLUP02_09085 BTB/POZ domain-containing protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CLUP02_18144 CPSF A subunit region K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E CLUP02_11061 WD repeat domain-containing protein K10570 ERCC8; DNA excision repair protein ERCC-8
E CLUP02_14450 WD domain-containing protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E CLUP02_14689 WD repeat domain-containing protein K11801 DCAF11; DDB1- and CUL4-associated factor 11
E CLUP02_07888 WD domain-containing protein K22382 WDR26; WD repeat-containing protein 26
E CLUP02_03923 WD repeat domain-containing protein K24752 WDR70; WD repeat-containing protein 70
E CLUP02_07026 WD domain-containing protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E CLUP02_01422 Skp1 family protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E CLUP02_03302 Skp1 family protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E CLUP02_03553 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E CLUP02_06039 Cullin family protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E CLUP02_13580 WD repeat domain-containing protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E CLUP02_10089 WD repeat domain-containing protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E CLUP02_12837 uncharacterized protein K03348 APC1; anaphase-promoting complex subunit 1
E CLUP02_03042 tetratricopeptide K03350 APC3; anaphase-promoting complex subunit 3
E CLUP02_03777 anaphase-promoting complex component Cut20/Apc4 K03351 APC4; anaphase-promoting complex subunit 4
E CLUP02_14736 anaphase-promoting complex protein K03352 APC5; anaphase-promoting complex subunit 5
E CLUP02_07756 tetratricopeptide K03353 APC6; anaphase-promoting complex subunit 6
E CLUP02_08168 tetratricopeptide K03355 APC8; anaphase-promoting complex subunit 8
C BRCC complex
D CLUP02_12465 DNA repair protein rhp51 K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D CLUP02_13543 uncharacterized protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D CLUP02_10619 SPRY domain-containing protein K23334 RANBP9_10; Ran-binding protein 9/10
D CLUP02_00784 armadillo repeat protein K23336 ARMC8; armadillo repeat-containing protein 8
D CLUP02_03821 uncharacterized protein K18624 MAEA; macrophage erythroblast attacher
D CLUP02_05073 vacuolar import and degradation protein K23335 GID4; glucose-induced degradation protein 4
D CLUP02_15490 ran binding protein in the microtubule-organising centre K23338 GID8; glucose-induced degradation protein 8
D CLUP02_07888 WD domain-containing protein K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
D CLUP02_01049 UBA domain-containing protein Ucp14 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D CLUP02_07659 TATA-binding protein interacting K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D CLUP02_04666 ubiquitin carboxyl-terminal hydrolase, family 1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D CLUP02_06236 ubiquitin carboxyl-terminal hydrolase, family 1 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D CLUP02_17268 ubiquitin carboxyl-terminal hydrolase K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D CLUP02_08180 ubiquitin carboxyl-terminal hydrolase K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D CLUP02_00406 ubiquitin carboxyl-terminal hydrolase K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D CLUP02_14790 ubiquitin carboxyl-terminal hydrolase K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D CLUP02_12602 ubiquitin carboxyl-terminal hydrolase K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D CLUP02_06428 ubiquitin carboxyl-terminal hydrolase K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D CLUP02_03802 ubiquitin carboxyl-terminal hydrolase K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D CLUP02_07743 ubiquitin carboxyl-terminal hydrolase K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D CLUP02_05290 ubiquitin carboxyl-terminal hydrolase K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D CLUP02_12101 ubiquitin carboxyl-terminal hydrolase K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D CLUP02_10333 OTU-like cysteine protease K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D CLUP02_01760 uncharacterized protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
C PPPDE
D CLUP02_11963 uncharacterized protein K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D CLUP02_08399 peptidase family C78 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
B UBL-specific proteases (ULPs)
C CLUP02_11751 Ulp1 protease family protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C CLUP02_04666 ubiquitin carboxyl-terminal hydrolase, family 1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C COP9 signalosome (CSN) complex
D CLUP02_04018 26S proteasome subunit RPN7 K12175 GPS1; COP9 signalosome complex subunit 1
D CLUP02_09391 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D CLUP02_10669 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D CLUP02_05464 PCI domain-containing protein K12178 COPS4; COP9 signalosome complex subunit 4
D CLUP02_02803 Mov34/MPN/PAD-1 family protein K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D CLUP02_17602 signalosome subunit K12179 COPS6; COP9 signalosome complex subunit 6
D CLUP02_13954 PCI domain-containing protein K12180 COPS7; COP9 signalosome complex subunit 7
D CLUP02_13783 PCI domain-containing protein K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024