+F Repair protein KO
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DNA Repair and Recombination Proteins - Cryptococcus neoformans var. neoformans JEC21
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E CNA06880 uracil DNA N-glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CNF00820 expressed protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E CNA00660 A/G-specific adenine DNA glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CNB02890 purine-specific oxidized base lesion DNA N-glycosylase, putative K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CNG03640 DNA-(apurinic or apyrimidinic site) lyase, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CNH01280 DNA-(apurinic or apyrimidinic site) lyase, putative K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E CNK02560 expressed protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E CNI04070 DNA-(apurinic or apyrimidinic site) lyase, putative K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F CNK00560 delta DNA polymerase, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F CNB00780 DNA polymerase Delta, small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
F CNC00140 expressed protein K03504 POLD3; DNA polymerase delta subunit 3
F CNH02825 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F CNK01430 DNA polymerase epsilon, catalytic subunit a, putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F CNF03830 epsilon DNA polymerase, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F CNM01210 expressed protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F CNG03660 DNA polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4), putative K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E CNM00880 DNA polymerase processivity factor, putative K04802 PCNA; proliferating cell nuclear antigen
E CND01190 flap endonuclease, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E CNI04170 DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E CNA04063 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other BER factors
E CND03200 expressed protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E CNC04800 conserved hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CNA07870 conserved hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E CNI01570 conserved hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F CND04530 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CNA07500 uv excision repair protein rhp23, putative K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F CNB03140 ubiquitin-protein ligase, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CNG04260 ubiquitin-protein ligase, putative K10609 CUL4; cullin 4
F CNG03940 conserved hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F CNL04270 DNA dependent ATPase, putative K15082 RAD7; DNA repair protein RAD7
F CNE00510 DNA repair protein rad16, putative K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F CNE03720 DNA-directed RNA polymerase II largest subunit, putative K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F CND03540 DNA-dependent RNA polymerase II RPB140, putative K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F CNE05120 RNA polymerase II subunit 3, putative K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F CND05580 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F CNA07710 DNA-directed RNA polymerases II 24 kda polypeptide, putative K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F CNI01770 DNA-directed RNA polymerases I, II, and III polypeptide, putative K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F CND04750 conserved hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F CNI02630 DNA-directed RNA polymerases I, II, and III 17.1 kda polypeptide, putative K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F CNL04765 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F CNB00680 DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide, putative K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F CNB02280 DNA-directed RNA polymerase II 13.3 kda polypeptide, putative K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F CNB03140 ubiquitin-protein ligase, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CNG04260 ubiquitin-protein ligase, putative K10609 CUL4; cullin 4
F CNG03940 conserved hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F CNB03940 cell growth-related protein, putative K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E CNA05940 general RNA polymerase II transcription factor, putative K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E CNA05570 general RNA polymerase II transcription factor, putative K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E CNC03130 expressed protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E CNI01660 RNA polymerase II transcription factor, putative K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E CNM00130 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E CNN01190 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E CNA06380 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E CNN01700 cyclin-dependent protein kinase, putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E CNI01430 cyclin-dependent protein kinase regulator, putative K06634 CCNH; cyclin H
E CNF00950 transcription/repair factor TFIIH subunit Tfb3, putative K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E CND02690 damaged DNA binding protein, putative K07466 RFA1; replication factor A1
E CND04360 conserved hypothetical protein K10739 RFA2; replication factor A2
E CNB03040 single-stranded DNA binding protein 12k chain, putative K10740 RPA3; replication factor A3
D Other NER factors
E CNG01380 hydrophilic protein, putative K10847 XPA; DNA-repair protein complementing XP-A cells
E CNF01110 mating-type switching protein swi10, putative K10849 ERCC1; DNA excision repair protein ERCC-1
E CNH01820 conserved hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E CNA03100 single-stranded DNA specific endodeoxyribonuclease, putative K10846 ERCC5; DNA excision repair protein ERCC-5
E CNI04170 DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CNE00920 conserved hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E CNG04610 ubiquitin-protein ligase, putative K03869 CUL3; cullin 3
E CNA02410 transcriptional elongation regulator, putative K03872 ELOC; elongin-C
E CNH01130 pof4 protein, putative K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CNA07480 DNA mismatch repair protein MSH2, putative K08735 MSH2; DNA mismatch repair protein MSH2
E CNC01550 conserved hypothetical protein K08736 MSH3; DNA mismatch repair protein MSH3
E CNK02590 mismatch repair-related protein, putative K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E CNE04630 DNA binding protein, putative K08734 MLH1; DNA mismatch repair protein MLH1
E CNC02500 ATPase, putative K10858 PMS2; DNA mismatch repair protein PMS2
E CND01680 mismatch repair-related protein, putative K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E CNK00560 delta DNA polymerase, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E CNB00780 DNA polymerase Delta, small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
E CNC00140 expressed protein K03504 POLD3; DNA polymerase delta subunit 3
E CNH02825 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E CND02690 damaged DNA binding protein, putative K07466 RFA1; replication factor A1
E CND04360 conserved hypothetical protein K10739 RFA2; replication factor A2
E CNB03040 single-stranded DNA binding protein 12k chain, putative K10740 RPA3; replication factor A3
D RFC (replication factor C)
E CNK01320 purine nucleotide binding protein, putative K10754 RFC1; replication factor C subunit 1
E CNH00770 activator 1 41 kda subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
E CNG02470 Activator 1 40 kDa subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
E CNN00630 DNA replication factor, putative K10756 RFC3_5; replication factor C subunit 3/5
E CNB04440 DNA clamp loader, putative K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E CNM00880 DNA polymerase processivity factor, putative K04802 PCNA; proliferating cell nuclear antigen
E CNB00080 exonuclease, putative K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E CNI04170 DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CNI03070 conserved hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E CNE00700 meiotic DNA double-strand break processing-related protein, putative K10865 MRE11; double-strand break repair protein MRE11
E CNN01100 telomere maintenance protein, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E CNE00700 meiotic DNA double-strand break processing-related protein, putative K10865 MRE11; double-strand break repair protein MRE11
E CNN01100 telomere maintenance protein, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E CNG03110 conserved hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
E CNA06990 recombinase, putative K04482 RAD51; DNA repair protein RAD51
E CNC05410 hypothetical protein K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E CNA06990 recombinase, putative K04482 RAD51; DNA repair protein RAD51
E CNC05410 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E CNA03725 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E CNK02320 RAD57 protein, putative K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E CNB00790 DNA strand annealing, putative K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E CND02890 DNA supercoiling, putative K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E CNC03920 DNA supercoiling, putative K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E CND00110 ATP-dependent DNA helicase, putative K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E CNC04400 ATP-dependent DNA helicase hus2/rqh1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CNB01550 ATP dependent DNA helicase, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E CNC04400 ATP-dependent DNA helicase hus2/rqh1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CNB01550 ATP dependent DNA helicase, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CNJ00400 DNA topoisomerase type I, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CNG02490 expressed protein K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E CND02690 damaged DNA binding protein, putative K07466 RFA1; replication factor A1
E CND04360 conserved hypothetical protein K10739 RFA2; replication factor A2
E CNB03040 single-stranded DNA binding protein 12k chain, putative K10740 RPA3; replication factor A3
D Protein phosphatase 4
E CNA03970 conserved hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E CNC05220 protein serine/threonine phosphatase 4 regulatory subunit 1, putative K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E CNL03970 nucleus protein, putative K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E CND06390 nucleus protein, putative K22803 SMC5; structural maintenance of chromosomes protein 5
E CND03960 DNA repair-related protein, putative K22804 SMC6; structural maintenance of chromosomes protein 6
E CNH00270 DNA repair-related protein, putative K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E CND02680 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E CNE00690 nucleus protein, putative K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E CNK00980 expressed protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E CNB04120 endonuclease, putative K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E CNN01280 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E CNE00220 hypothetical protein K10991 SWI5; DNA repair protein Swi5/Sae3
E CNA03830 conserved hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E CNB01350 hypothetical protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CNF01960 conserved hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E CNC02220 expressed protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E CNM01670 conserved hypothetical protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E CNI03620 conserved hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E CNB01380 damaged DNA binding protein, putative K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E CNE00700 meiotic DNA double-strand break processing-related protein, putative K10865 MRE11; double-strand break repair protein MRE11
E CNN01100 telomere maintenance protein, putative K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E CNK00930 DNA ligase (ATP), putative K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E CNE02240 expressed protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E CNI01570 conserved hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E CNL05040 beta DNA polymerase, putative K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E CNA04063 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E CNC04800 conserved hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CNK01200 expressed protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E CNC04400 ATP-dependent DNA helicase hus2/rqh1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CNB01550 ATP dependent DNA helicase, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CNJ00400 DNA topoisomerase type I, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CNG02490 expressed protein K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
E CNG03110 conserved hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
D Other FA pathway factors
E CNM02280 conserved hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E CNA06990 recombinase, putative K04482 RAD51; DNA repair protein RAD51
E CNC05410 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E CNA03725 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E CNI02310 telomeric DNA binding protein, putative K11137 TELO2; telomere length regulation protein
E CNN00190 conserved hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E CND05500 conserved hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E CND00670 guanyl nucleotide binding protein, putative K23314 WRAP53; telomerase Cajal body protein 1
E CND00570 transcription factor, putative K24752 WDR70; WD repeat-containing protein 70
E CNI03070 conserved hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CNE03660 eta DNA polymerase, putative K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D CNL04490 conserved hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D CNA01660 conserved hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D CNB03700 zeta DNA polymerase, putative K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D CNA08010 ubiquitin-conjugating enzyme E2-17 kda, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D CNH01875 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CNA02850 DNA repair protein RAD5, putative K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D CNL05190 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3, putative K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CNJ01630 DNA repair protein RAD5, putative K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CNF00870 conserved hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D CNE03880 conserved hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D CNM00880 DNA polymerase processivity factor, putative K04802 PCNA; proliferating cell nuclear antigen
D CNG00580 expressed protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D CNE00810 expressed protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D CNH03430 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
D CNB05390 expressed protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D CNB04200 RAD17 isoform 4, putative K06662 HRAD17; cell cycle checkpoint protein
D CNH00770 activator 1 41 kda subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
D CNG02470 Activator 1 40 kDa subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
D CNN00630 DNA replication factor, putative K10756 RFC3_5; replication factor C subunit 3/5
D CNB04440 DNA clamp loader, putative K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D CNB05390 expressed protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D CNF00340 conserved hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D CNJ00415 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D CNC00620 hypothetical protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D CNI02310 telomeric DNA binding protein, putative K11137 TELO2; telomere length regulation protein
D CNB00940 conserved hypothetical protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D CNH02170 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
D CNA06510 cytoplasm protein, putative K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D CNE03070 UVSB PI-3 kinase, putative K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D CNF02070 telomere length control protein, putative K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D CNG04000 hypothetical protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D CNC00870 Mih1p, putative K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D CNL03930 14-3-3 protein, putative K06630 YWHAE; 14-3-3 protein epsilon
D CNL04130 protein threonine/tyrosine kinase, putative K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D CNG03960 MYT1 kinase, putative K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D CNG02130 conserved hypothetical protein K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D CNI00460 ATPase, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
D CNF04070 conserved hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D CNC01540 DNA-directed DNA polymerase, putative K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D CNG04070 conserved hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D CNM01070 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D CNA02540 conserved hypothetical protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D CNN01650 DNA dependent ATPase, putative K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D CNC02380 nuclear matrix protein NMP200, putative K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D CNK01590 conserved hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D CNF02850 conserved hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D CNG03060 nuclear mRNA splicing, via spliceosome-related protein, putative K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D CNJ02760 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CNM01430 dUTP diphosphatase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CNE03330 ribonucleoside-diphosphate reductase large chain, putative K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D CNK02580 ribonucleoside-diphosphate reductase, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D CNK01530 ribonucleotide reductase small subunit, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E CNA06880 uracil DNA N-glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CNL04530 DNA-3-methyladenine glycosidase, putative K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CNA00660 A/G-specific adenine DNA glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CNH00550 conserved hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CNG03640 DNA-(apurinic or apyrimidinic site) lyase, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CNC06510 ATP-dependent DNA helicase pcra, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E CNC06510 ATP-dependent DNA helicase pcra, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CNJ02760 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CNM01430 dUTP diphosphatase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024