+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Cryptococcus neoformans var. grubii H99</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        CNAG_01631 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        CNAG_01664 CMGC/CDK/CDC2 protein kinase	K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] 
E        CNAG_06445 CMGC/CDK/CDK7 protein kinase	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        CNAG_03610 mRNA guanylyltransferase	K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] 
E        CNAG_06549 mRNA-capping enzyme subunit beta	K01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74] 
D      Cap binding complex
E        CNAG_06753 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        CNAG_05196 nuclear cap-binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        CNAG_03491 cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        CNAG_02111 protein Clp1	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        CNAG_00184 pre-mRNA cleavage complex 2 protein Pcf11	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        CNAG_05895 protein CFT1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        CNAG_01099 cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        CNAG_05629 endoribonuclease YSH1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        CNAG_03604 mRNA 3'-end-processing protein YTH1	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        CNAG_01526 cleavage and polyadenylation specificity factor subunit 4	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        CNAG_02530 hypothetical protein	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        CNAG_01217 protein MPE1	K15541 MPE1; protein MPE1 
E        CNAG_01630 polyadenylation factor subunit 2	K15542 PFS2; polyadenylation factor subunit 2 
E        CNAG_03070 compass component swd2	K14962 WDR82; COMPASS component SWD2 
E        CNAG_03673 serine/threonine-protein phosphatase PP-Z1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        CNAG_03706 serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        CNAG_01054 RNA polymerase II subunit A domain phosphatase SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        CNAG_04541 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        CNAG_04557 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        CNAG_03761 mRNA 3'-end-processing protein RNA14	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        CNAG_05787 symplekin	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        CNAG_04840 small nuclear ribonucleoprotein B and B'	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        CNAG_04050 small nuclear ribonucleoprotein D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        CNAG_04155 small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        CNAG_01198 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        CNAG_04914 small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        CNAG_01099 cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        CNAG_05629 endoribonuclease YSH1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        CNAG_04541 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        CNAG_04557 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        CNAG_05787 symplekin	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        CNAG_04204 transcription elongation factor SPT4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        CNAG_00641 transcription elongation factor SPT5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        CNAG_02150 mRNA methyltransferase	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        CNAG_04487 transcription regulator	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        CNAG_02784 methyltransferase	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        CNAG_00551 poly(A) polymerase	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        CNAG_02597 hypothetical protein	K13192 RBM26; RNA-binding protein 26 
C    Other processing factors
D      CNAG_05055 DNA/RNA-binding protein KIN17	K13102 KIN; DNA/RNA-binding protein KIN17 
D      CNAG_05311 arsenite-resistant protein ASR2	K27103 SRRT; serrate RNA effector molecule 
D      CNAG_00286 hypothetical protein	K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        CNAG_02898 RNA-binding protein 8A	K12876 RBM8A; RNA-binding protein 8A 
E        CNAG_00994 protein mago nashi	K12877 MAGOH; protein mago nashi 
E        CNAG_03186 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        CNAG_03249 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        CNAG_00741 ATP-dependent RNA helicase SUB2	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        CNAG_01548 ATP-dependent RNA helicase FAL1	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        CNAG_03282 hypothetical protein	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        CNAG_04679 histone deacetylase complex subunit	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        CNAG_02995 RNA-binding protein with serine-rich domain 1	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        CNAG_06796 serine/arginine repetitive matrix protein 1	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        CNAG_03235 THO complex subunit 1	K12878 THOC1; THO complex subunit 1 
E        CNAG_03942 THO complex subunit 2	K12879 THOC2; THO complex subunit 2 
E        CNAG_03186 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        CNAG_03249 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        CNAG_04234 hypothetical protein	K13174 THOC5; THO complex subunit 5 
D      TREX-2 complex
E        CNAG_06402 26S proteasome complex subunit DSS1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        CNAG_01396 protein SUS1	K11368 ENY2; enhancer of yellow 2 transcription factor 
E        CNAG_05655 EF-hand calcium-binding protein	K16466 CETN3; centrin-3 
E        CNAG_02032 nuclear export factor	K23719 SAC3; nuclear mRNA export protein SAC3 
D      Nuclear pore complex
E        CNAG_07925 nucleoprotein TPR	K09291 TPR; nucleoprotein TPR 
E        CNAG_06077 mRNA export factor	K14298 RAE1; mRNA export factor 
E        CNAG_04194 protein transporter SEC13	K14004 SEC13; protein transport protein SEC13 
E        CNAG_03917 nuclear pore complex protein Nup85	K14304 NUP85; nuclear pore complex protein Nup85 
E        CNAG_04670 hypothetical protein	K14308 NUP54; nuclear pore complex protein Nup54 
E        CNAG_01199 nuclear pore complex protein Nup62	K14306 NUP62; nuclear pore complex protein Nup62 
E        CNAG_02816 nuclear pore complex protein Nup93	K14309 NUP93; nuclear pore complex protein Nup93 
E        CNAG_07469 nuclear pore complex protein Nup98-Nup96	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        CNAG_04149 nuclear pore complex protein Nup107	K14301 NUP107; nuclear pore complex protein Nup107 
E        CNAG_05353 nuclear pore complex protein Nup133	K14300 NUP133; nuclear pore complex protein Nup133 
E        CNAG_05804 nuclear pore complex protein Nup188	K14311 NUP188; nuclear pore complex protein Nup188 
E        CNAG_01000 nuclear pore complex protein Nup155	K14312 NUP155; nuclear pore complex protein Nup155 
E        CNAG_01053 nuclear pore complex protein Nup160	K14303 NUP160; nuclear pore complex protein Nup160 
E        CNAG_02547 nuclear pore complex protein Nup205	K14310 NUP205; nuclear pore complex protein Nup205 
E        CNAG_00411 nucleoporin p58/p45	K14307 NUPL1; nucleoporin p58/p45 
E        CNAG_01045 hypothetical protein	K14315 NDC1; nucleoporin NDC1 
E        CNAG_06772 nucleoporin SEH1	K14299 SEH1; nucleoporin SEH1 
E        CNAG_06550 nucleoporin family protein	K18715 NUP159; nucleoporin NUP159 
E        CNAG_01342 hypothetical protein	K18716 NUP42; nucleoporin NUP42 
E        CNAG_01330 hypothetical protein	K18719 NUP82; nucleoporin NUP82 
E        CNAG_00666 nucleoporin nsp1	K18721 NUP1; nucleoporin NUP1 
E        CNAG_07322 hypothetical protein	K18722 NUP2; nucleoporin NUP2 
E        CNAG_05655 EF-hand calcium-binding protein	K16466 CETN3; centrin-3 
E        CNAG_04745 hypothetical protein	K18723 GLE1; nucleoporin GLE1 
E        CNAG_04211 nuclear RNA export factor 1/2	K14284 NXF; nuclear RNA export factor 
E        CNAG_03020 hypothetical protein	K14285 NXT1_2; NTF2-related export protein 1/2 
E        CNAG_01510 hypothetical protein	K18725 POM152; nucleoporin POM152 
D      Ran-mediated transport factors
E        CNAG_02257 GTP-binding nuclear protein spi1	K07936 RAN; GTP-binding nuclear protein Ran 
E        CNAG_07688 hypothetical protein	K18726 FAF2; FAS-associated factor 2 
E        CNAG_04851 transitional endoplasmic reticulum ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        CNAG_00900 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        CNAG_03418 exportin-1	K14290 XPO1; exportin-1 
E        CNAG_01197 ran GTPase-activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        CNAG_01833 translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_01943 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_05843 translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_00785 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        CNAG_00386 translation initiation factor 4G	K03260 EIF4G; translation initiation factor 4G 
E        CNAG_00402 translation initiation factor 4G	K03260 EIF4G; translation initiation factor 4G 
E        CNAG_06906 translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        CNAG_00809 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        CNAG_05745 cytoplasmic protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        CNAG_04441 polyadenylate-binding protein, cytoplasmic and nuclear	K13126 PABPC; polyadenylate-binding protein 
E        CNAG_04131 antiviral helicase SKI2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        CNAG_04393 RNA helicase	K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] 
E        CNAG_02656 translation machinery-associated protein 20	K07575 MCTS; malignant T-cell-amplified sequence 
E        CNAG_02482 translation machinery-associated protein 22	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        CNAG_00577 hypothetical protein	K14294 WIBG; partner of Y14 and mago 
E        CNAG_06474 RNA-binding protein Musashi	K14411 MSI; RNA-binding protein Musashi 
E        CNAG_03987 elongation factor 1 alpha-like protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        CNAG_07309 mRNA surveillance protein pelota	K06965 PELO; protein pelota 
E        CNAG_03968 polyadenylate-binding protein 2	K14396 PABPN1; polyadenylate-binding protein 2 
E        CNAG_04362 ATP-dependent RNA helicase DBP5	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        CNAG_02426 pre-mRNA-splicing factor SYF1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        CNAG_04273 hypothetical protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        CNAG_06545 pim1 protein RNA transporter 2	K11493 RCC1; regulator of chromosome condensation 
E        CNAG_06280 nuclear protein	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        CNAG_02948 peptide chain release factor 1	K03265 ETF1; peptide chain release factor subunit 1 
E        CNAG_05826 translation elongation factor Tu	K03267 ERF3; peptide chain release factor subunit 3 
E        CNAG_01807 ATP-dependent helicase	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        CNAG_05829 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        CNAG_03276 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        CNAG_02177 serine/threonine-protein phosphatase PP2A catalytic subunit	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        CNAG_07914 protein phosphatase 2 (formerly 2A), regulatory subunit A	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        CNAG_06696 protein phosphatase PP2A regulatory subunit B	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        CNAG_05634 protein phosphatase 2 (formerly 2A), regulatory subunit B'	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        CNAG_07351 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        CNAG_05745 cytoplasmic protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        CNAG_03992 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        CNAG_03675 pumilio domain-containing protein	K14844 PUF6; pumilio homology domain family member 6 
E        CNAG_01182 cytoplasmic protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        CNAG_04584 poly(rC)-binding protein 2/3/4	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        CNAG_06971 hypothetical protein	K10357 MYO5; myosin V 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        CNAG_06125 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        CNAG_00417 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
D      Other mRNA localization factors
E        CNAG_03345 hypothetical protein	K18748 SSD1; protein SSD1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        CNAG_02175 5'-3' exoribonuclease 1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        CNAG_04609 argonaute	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        CNAG_01833 translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_01943 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_05843 translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        CNAG_01807 ATP-dependent helicase	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        CNAG_00809 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        CNAG_01537 ATP-dependent RNA helicase VAD1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        CNAG_05285 hypothetical protein	K18749 LSM14; protein LSM14 
E        CNAG_02457 importin beta-2 subunit	K18752 TNPO1; transportin-1 
E        CNAG_07351 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        CNAG_00396 AGC/PKA protein kinase	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        CNAG_04162 AGC/PKA protein kinase	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        CNAG_04570 hypothetical protein	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        CNAG_06903 mRNA-decapping enzyme subunit 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        CNAG_04980 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        CNAG_01666 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        CNAG_00781 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        CNAG_02901 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        CNAG_00016 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        CNAG_06426 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        CNAG_05241 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        CNAG_00557 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        CNAG_06971 hypothetical protein	K10357 MYO5; myosin V 
E        CNAG_03787 tubulin alpha-1A chain	K07374 TUBA; tubulin alpha 
E        CNAG_02936 CCR4-NOT transcription complex subunit 1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        CNAG_01852 CCR4-NOT transcription complex subunit 2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        CNAG_06635 CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        CNAG_03839 CCR4-NOT transcription complex subunit 4	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        CNAG_03190 glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        CNAG_05171 CCR4-NOT transcription complex subunit 7/8	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        CNAG_01377 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        CNAG_04821 PAB-dependent poly(A)-specific ribonuclease subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        CNAG_00665 DNA topoisomerase 2-associated protein PAT1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        CNAG_05829 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        CNAG_03276 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
E        CNAG_01359 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        CNAG_03314 YTH domain family 2	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        CNAG_01413 nucleolysin TIA-1/TIAR	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        CNAG_04441 polyadenylate-binding protein, cytoplasmic and nuclear	K13126 PABPC; polyadenylate-binding protein 
E        CNAG_03722 RAN protein binding protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        CNAG_05366 translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        CNAG_00785 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        CNAG_01548 ATP-dependent RNA helicase FAL1	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        CNAG_06906 translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        CNAG_00386 translation initiation factor 4G	K03260 EIF4G; translation initiation factor 4G 
E        CNAG_00402 translation initiation factor 4G	K03260 EIF4G; translation initiation factor 4G 
E        CNAG_05465 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        CNAG_04211 nuclear RNA export factor 1/2	K14284 NXF; nuclear RNA export factor 
E        CNAG_01563 histone deacetylase 6/10	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        CNAG_06903 mRNA-decapping enzyme subunit 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        CNAG_01537 ATP-dependent RNA helicase VAD1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        CNAG_00665 DNA topoisomerase 2-associated protein PAT1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        CNAG_04980 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        CNAG_01666 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        CNAG_00781 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        CNAG_02901 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        CNAG_00016 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        CNAG_06426 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        CNAG_05241 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        CNAG_00557 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        CNAG_02175 5'-3' exoribonuclease 1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        CNAG_05797 5'-3' exoribonuclease 2	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        CNAG_06359 scavenger mRNA-decapping enzyme DcpS	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        CNAG_01033 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
E        CNAG_00089 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        CNAG_01141 exosome complex component RRP40	K03681 RRP40; exosome complex component RRP40 
E        CNAG_07416 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        CNAG_01381 hypothetical protein	K12590 RRP46; exosome complex component RRP46 
E        CNAG_04839 exosome complex component MTR3, animal type	K12587 MTR3; exosome complex component MTR3 
E        CNAG_05811 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
E        CNAG_00853 exosome complex component RRP43	K12586 RRP43; exosome complex component RRP43 
E        CNAG_01693 exosome complex component RRP45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        CNAG_00940 exosome complex exonuclease DIS3/RRP44	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        CNAG_02773 exosome complex exonuclease RRP6	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        CNAG_00195 exosome complex protein LRP1	K12592 C1D; exosome complex protein LRP1 
D      TRAMP complex
E        CNAG_01885 DNA polymerase sigma subunit	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        CNAG_00241 protein AIR1/2	K12597 AIR1_2; protein AIR1/2 
E        CNAG_01398 ATP-dependent RNA helicase DOB1	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        CNAG_04131 antiviral helicase SKI2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        CNAG_01039 superkiller protein 3	K12600 SKI3; superkiller protein 3 
E        CNAG_05219 hypothetical protein	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        CNAG_03190 glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        CNAG_02936 CCR4-NOT transcription complex subunit 1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        CNAG_01852 CCR4-NOT transcription complex subunit 2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        CNAG_06635 CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        CNAG_03839 CCR4-NOT transcription complex subunit 4	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        CNAG_05171 CCR4-NOT transcription complex subunit 7/8	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        CNAG_01717 cell differentiation protein rcd1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        CNAG_02059 CCR4-NOT complex subunit CAF16	K12608 CAF16; CCR4-NOT complex subunit CAF16 
E        CNAG_00777 CCR4-NOT transcriptional complex subunit CAF120	K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120 
D      Pan complex
E        CNAG_01377 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        CNAG_04821 PAB-dependent poly(A)-specific ribonuclease subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        CNAG_02368 hypothetical protein	K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-] 
E        CNAG_06359 scavenger mRNA-decapping enzyme DcpS	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        CNAG_06131 hypothetical protein	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        CNAG_06103 RNA binding protein	K27407 VTS1; RNA-binding protein VTS1 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        CNAG_06643 ribonuclease III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        CNAG_00288 oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        CNAG_03072 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        CNAG_06868 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        CNAG_04676 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        CNAG_05199 chaperone DnaK	K04043 dnaK; molecular chaperone DnaK 
E        CNAG_03891 hsp60-like protein	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        CNAG_00089 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        CNAG_01033 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        CNAG_07416 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        CNAG_05811 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
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#Last updated: April 25, 2024