+F Repair protein KO
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DNA Repair and Recombination Proteins - Capnocytophaga ochracea
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Coch_0065 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Coch_2033 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Coch_0980 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Coch_2158 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Coch_0751 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Coch_0065 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Coch_2033 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Coch_0980 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Coch_2158 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Coch_1451 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E Coch_0347 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Coch_1559 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Coch_1092 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Coch_1339 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Coch_1893 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Coch_1442 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
E Coch_1283 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
E Coch_2070 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Coch_1092 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Coch_1559 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Coch_0426 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Coch_0433 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Coch_1173 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Coch_1894 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Coch_0842 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E Coch_2031 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E Coch_2145 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E Coch_0371 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Coch_1752 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Coch_0460 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Coch_1239 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Coch_0076 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Coch_0008 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Coch_1879 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Coch_1559 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Coch_2070 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Coch_0979 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Coch_0562 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E Coch_0877 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
E Coch_2150 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Coch_0804 recA protein K03553 recA; recombination protein RecA
E Coch_0310 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Coch_1708 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Coch_0079 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Coch_2035 transcriptional regulator, TrmB K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Coch_1540 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Coch_1419 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Coch_0804 recA protein K03553 recA; recombination protein RecA
E Coch_2129 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Coch_1183 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Coch_1975 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Coch_0347 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Coch_2156 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Coch_2171 recombination protein RecR K06187 recR; recombination protein RecR
E Coch_1845 Sigma 54 interacting domain protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E Coch_0310 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Coch_1708 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Coch_0079 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E Coch_1540 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Coch_1419 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E Coch_1849 protein of unknown function DUF853 NPT hydrolase putative K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Coch_2024 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Coch_1453 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Coch_0334 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Coch_1479 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F Coch_1967 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Coch_0347 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Coch_2156 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Coch_2171 recombination protein RecR K06187 recR; recombination protein RecR
F Coch_1559 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Coch_1895 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Coch_1951 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Coch_1339 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Coch_1893 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Coch_1442 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Coch_0662 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Coch_0804 recA protein K03553 recA; recombination protein RecA
D Coch_1845 Sigma 54 interacting domain protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D Coch_0979 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Coch_0562 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D Coch_0877 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
D Coch_0959 DNA-damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D Coch_1030 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D Coch_0751 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Coch_1963 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Coch_1205 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D Coch_1856 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024