+F Repair protein KO
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DNA Repair and Recombination Proteins - Carica papaya (papaya)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 110817826 LOW QUALITY PROTEIN: DNA oxidative demethylase ALKBH2 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 110811155 LOW QUALITY PROTEIN: DExH-box ATP-dependent RNA helicase DExH14 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 110817579 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 110824350 uracil-DNA glycosylase, mitochondrial-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110826000 uracil-DNA glycosylase, mitochondrial-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110811734 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 110821733 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 110820024 uncharacterized protein LOC110820024 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 110813540 N-glycosylase/DNA lyase OGG1 isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 110816850 putative DNA glycosylase At3g47830 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 110822146 LOW QUALITY PROTEIN: DNA-(apurinic or apyrimidinic site) lyase 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 110816122 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 110811657 DNA polymerase delta small subunit isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
F 110812531 uncharacterized protein LOC110812531 K03504 POLD3; DNA polymerase delta subunit 3
F 110816028 uncharacterized protein LOC110816028 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 110817276 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 110810725 DNA polymerase epsilon subunit B isoform X1 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 110817309 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E 110810031 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 110815360 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E 110821150 DNA-repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
D Other BER factors
E 110806742 LOW QUALITY PROTEIN: tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 110809488 transcription factor bHLH140 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 110812493 polynucleotide 3'-phosphatase ZDP K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 110822719 DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 110815003 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 110817266 poly [ADP-ribose] polymerase 3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 110821398 poly [ADP-ribose] polymerase 2 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 110809722 LOW QUALITY PROTEIN: DNA repair protein RAD4 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 110823997 ubiquitin receptor RAD23d-like K10839 RAD23; UV excision repair protein RAD23
F 110813179 ubiquitin receptor RAD23b K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 110817690 RING-box protein 1a K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 110815779 cullin-4-like K10609 CUL4; cullin 4
F 110807586 cullin-4 K10609 CUL4; cullin 4
F 110819767 DNA damage-binding protein 1a K10610 DDB1; DNA damage-binding protein 1
F 110810054 protein DAMAGED DNA-BINDING 2 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
F 110809259 uncharacterized protein LOC110809259 isoform X1 K15082 RAD7; DNA repair protein RAD7
F 110817715 uncharacterized protein LOC110817715 isoform X1 K15082 RAD7; DNA repair protein RAD7
F 110811532 DNA repair protein RAD16-like K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 110822512 DNA-directed RNA polymerase II subunit 1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 110817850 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 110806508 DNA-directed RNA polymerases II, IV and V subunit 3-like K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 110823262 DNA-directed RNA polymerase II subunit 4-like K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 110806915 DNA-directed RNA polymerase II subunit 4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 110817786 DNA-directed RNA polymerases IV and V subunit 4-like isoform X1 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 110820595 DNA-directed RNA polymerases II and IV subunit 5A K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 110822628 DNA-directed RNA polymerase V subunit 5A K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 110825160 DNA-directed RNA polymerases II, IV and V subunit 6A-like K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 110812172 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 110821511 DNA-directed RNA polymerases II, IV and V subunit 8B-like K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 110821838 DNA-directed RNA polymerases II, IV and V subunit 8B-like K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 110821224 DNA-directed RNA polymerases II, IV and V subunit 9B K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 110820688 DNA-directed RNA polymerase subunit 10-like protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 110809333 DNA-directed RNA polymerases II, IV and V subunit 11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 110818360 DNA-directed RNA polymerases II, IV and V subunit 12 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 110817690 RING-box protein 1a K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 110815779 cullin-4-like K10609 CUL4; cullin 4
F 110807586 cullin-4 K10609 CUL4; cullin 4
F 110819767 DNA damage-binding protein 1a K10610 DDB1; DNA damage-binding protein 1
F 110808425 DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 110807650 protein CHROMATIN REMODELING 8 isoform X1 K10841 ERCC6; DNA excision repair protein ERCC-6
F 110811036 LOW QUALITY PROTEIN: UV-stimulated scaffold protein A homolog K23720 UVSSA; UV-stimulated scaffold protein A
D TFIIH complex
E 110807187 DNA repair helicase XPB1 isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 110814710 DNA repair helicase XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 110807179 probable RNA polymerase II transcription factor B subunit 1-1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 110808556 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 110816624 RNA polymerase II transcription factor B subunit 4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 110817799 LOW QUALITY PROTEIN: RNA polymerase II transcription factor B subunit 2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 110817547 RNA polymerase II transcription factor B subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 110807499 cyclin-dependent kinase D-2 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 110823421 cyclin-dependent kinase D-3 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 110817670 cyclin-H1-1 isoform X1 K06634 CCNH; cyclin H
E 110806727 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 110808650 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit E-like K07466 RFA1; replication factor A1
E 110817668 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
E 110813464 replication protein A 70 kDa DNA-binding subunit B-like K07466 RFA1; replication factor A1
E 110811389 replication protein A 32 kDa subunit A K10739 RFA2; replication factor A2
E 110826403 replication protein A 32 kDa subunit B-like K10739 RFA2; replication factor A2
E 110822723 replication protein A 14 kDa subunit B K10740 RPA3; replication factor A3
D Other NER factors
E 110812430 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 110825644 DNA repair endonuclease UVH1-like isoform X1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 110808492 LOW QUALITY PROTEIN: DNA repair protein UVH3 K10846 ERCC5; DNA excision repair protein ERCC-5
E 110818346 LOW QUALITY PROTEIN: MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 110809124 LOW QUALITY PROTEIN: cullin-3A-like K03869 CUL3; cullin 3
E 110812088 elongin-C K03872 ELOC; elongin-C
E 110815701 uncharacterized protein LOC110815701 isoform X1 K03873 ELOB; elongin-B
E 110815117 transcription elongation factor B polypeptide 3 K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 110825125 DNA mismatch repair protein MSH2 K08735 MSH2; DNA mismatch repair protein MSH2
E 110810275 DNA mismatch repair protein MSH3 K08736 MSH3; DNA mismatch repair protein MSH3
E 110818630 DNA mismatch repair protein MSH7 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6
E 110815038 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH6-like K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 110815008 DNA mismatch repair protein MLH1 K08734 MLH1; DNA mismatch repair protein MLH1
E 110821308 DNA mismatch repair protein PMS1 K10858 PMS2; DNA mismatch repair protein PMS2
E 110822205 DNA mismatch repair protein MLH3-like K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 110816122 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 110811657 DNA polymerase delta small subunit isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
E 110812531 uncharacterized protein LOC110812531 K03504 POLD3; DNA polymerase delta subunit 3
E 110816028 uncharacterized protein LOC110816028 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 110808650 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit E-like K07466 RFA1; replication factor A1
E 110817668 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
E 110813464 replication protein A 70 kDa DNA-binding subunit B-like K07466 RFA1; replication factor A1
E 110811389 replication protein A 32 kDa subunit A K10739 RFA2; replication factor A2
E 110826403 replication protein A 32 kDa subunit B-like K10739 RFA2; replication factor A2
E 110822723 replication protein A 14 kDa subunit B K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 110810672 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 110813509 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 110812802 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 110813508 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 110807822 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 110822243 uncharacterized protein LOC110822243 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
E 110817085 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 110810031 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 110823316 exonuclease 1 isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 110819701 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 110815748 WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 110820614 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 110807951 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 110810219 nijmegen breakage syndrome 1 protein isoform X1 K10867 NBN; nibrin
D BRCA1-core complex
E 110819765 protein BREAST CANCER SUSCEPTIBILITY 1 homolog K10683 BARD1; BRCA1-associated RING domain protein 1
E 110807674 BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 110822110 uncharacterized protein LOC110822110 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 110817991 BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
E 110825871 uncharacterized protein LOC110825871 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 110818216 Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 110813529 LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E 110819414 BRCT domain-containing protein At4g02110 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 110820614 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 110807951 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 110810219 nijmegen breakage syndrome 1 protein isoform X1 K10867 NBN; nibrin
D BRCA complex
E 110822814 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 110825838 DNA repair protein RAD51 homolog K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 110825838 DNA repair protein RAD51 homolog K04482 RAD51; DNA repair protein RAD51
E 110808539 DNA repair protein RAD51 homolog 2 K10869 RAD51L1; RAD51-like protein 1
E 110819456 DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 110826262 DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3
E 110813644 DNA repair protein XRCC2 homolog isoform X1 K10879 XRCC2; DNA-repair protein XRCC2
E 110811104 DNA repair protein XRCC3 homolog K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 110826297 DNA repair RAD52-like protein 1, mitochondrial K26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial
E 110809295 DNA repair RAD52-like protein 2, chloroplastic K26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic
D Rad54 family proteins
E 110812586 SNF2 domain-containing protein CLASSY 3 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 110819231 LOW QUALITY PROTEIN: SNF2 domain-containing protein CLASSY 2-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 110813686 protein CHROMATIN REMODELING 25 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E 110808648 mediator of RNA polymerase II transcription subunit 34 isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 110815308 ATP-dependent DNA helicase Q-like 1 isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 110815478 ATP-dependent DNA helicase Q-like SIM K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 110817328 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110822523 ATP-dependent DNA helicase Q-like 3 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110815962 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 5 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 110817328 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110822523 ATP-dependent DNA helicase Q-like 3 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110807950 DNA topoisomerase 3-beta isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110816468 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110822948 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 110815544 uncharacterized protein LOC110815544 isoform X1 K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E 110808650 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit E-like K07466 RFA1; replication factor A1
E 110817668 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
E 110813464 replication protein A 70 kDa DNA-binding subunit B-like K07466 RFA1; replication factor A1
E 110811389 replication protein A 32 kDa subunit A K10739 RFA2; replication factor A2
E 110826403 replication protein A 32 kDa subunit B-like K10739 RFA2; replication factor A2
E 110822723 replication protein A 14 kDa subunit B K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 110820748 serine/threonine-protein phosphatase PP-X isozyme 2 K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 110816306 serine/threonine-protein phosphatase 4 regulatory subunit 2-A isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 110821364 serine/threonine-protein phosphatase 4 regulatory subunit 3 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
E 110813654 LOW QUALITY PROTEIN: uncharacterized protein LOC110813654 K19022 AP5B1; AP-5 complex subunit beta-1
E 110819848 LOW QUALITY PROTEIN: AP-5 complex subunit mu-like K19023 AP5M1; AP-5 complex subunit mu-1
D SMC5-SMC6 complex
E 110809288 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 110809462 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6B-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 110810699 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 110812302 E3 SUMO-protein ligase MMS21 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 110811740 non-structural maintenance of chromosomes element 4 homolog A-like isoform X1 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 110812911 crossover junction endonuclease EME1B-like isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 110806805 crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 110808781 protein DSS1 HOMOLOG ON CHROMOSOME V-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 110806782 structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 110823887 uncharacterized protein LOC110823887 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 110810375 flap endonuclease GEN-like 2 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 110812908 uncharacterized protein LOC110812908 K19026 SPG11; spatacsin
E 110806630 uncharacterized protein LOC110806630 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 110822263 protein MRG1 K11339 MORF4L1; mortality factor 4-like protein 1
E 110818697 protein MRG1-like isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1
E 110816348 LOW QUALITY PROTEIN: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 110813122 LOW QUALITY PROTEIN: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 110807429 ATPase family AAA domain-containing protein FIGL1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 110825088 zinc finger SWIM domain-containing protein 7 isoform X1 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 110820626 uncharacterized protein LOC110820626 K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E 110814306 single-stranded DNA-binding protein WHY1, chloroplastic-like K26559 WHY1; single-stranded DNA-binding protein WHY1
E 110826296 single-stranded DNA-binding protein WHY2, mitochondrial isoform X1 K26561 WHY2; single-stranded DNA-binding protein WHY2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 110812501 ATP-dependent DNA helicase 2 subunit KU70 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 110819525 ATP-dependent DNA helicase 2 subunit KU80 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E 110820614 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 110807951 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 110811056 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 110814034 LOW QUALITY PROTEIN: DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4
D X-family DNA polymerases
E 110822719 DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 110809488 transcription factor bHLH140 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 110808032 uncharacterized protein LOC110808032 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 110823352 LOW QUALITY PROTEIN: uncharacterized protein LOC110823352 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
C FA (Fanconi anemia) pathway
D FA core complex
E 110809101 E3 ubiquitin-protein ligase FANCL isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 110813251 LOW QUALITY PROTEIN: DEAD-box ATP-dependent RNA helicase FANCM K10896 FANCM; fanconi anemia group M protein
D FA core complex binding factors
E 110820514 protein MHF1 homolog K11511 APITD1; centromere protein S
E 110822978 protein MHF2 homolog K15360 STRA13; centromere protein X
E 110818646 uncharacterized protein LOC110818646 isoform X1 K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 110817328 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110822523 ATP-dependent DNA helicase Q-like 3 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110807950 DNA topoisomerase 3-beta isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110816468 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110822948 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 110815544 uncharacterized protein LOC110815544 isoform X1 K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E 110821819 Fanconi anemia group D2 protein isoform X1 K10891 FANCD2; fanconi anemia group D2 protein
E 110819874 LOW QUALITY PROTEIN: Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 110822814 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 110818216 Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 110821695 fanconi-associated nuclease 1 homolog K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 110825838 DNA repair protein RAD51 homolog K04482 RAD51; DNA repair protein RAD51
E 110819456 DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 110814714 LOW QUALITY PROTEIN: uncharacterized protein LOC110814714 K11137 TELO2; telomere length regulation protein
E 110809632 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 110806404 phytochrome-associated serine/threonine-protein phosphatase K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E 110817805 telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
E 110811552 WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 110815748 WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 110810424 DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 110810468 LOW QUALITY PROTEIN: DNA repair protein REV1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 110815393 DNA polymerase zeta catalytic subunit-like K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D 110815295 DNA polymerase zeta catalytic subunit-like K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D 110819745 ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110807785 ubiquitin-conjugating enzyme E2 2-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110809103 ubiquitin-conjugating enzyme E2 1-like isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110807111 ubiquitin-conjugating enzyme E2 2-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110815537 DNA repair protein RAD5A isoform X1 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D 110811286 putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 110823871 ubiquitin-conjugating enzyme E2 variant 1A K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 110810615 ubiquitin-conjugating enzyme E2 variant 1C K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 110810891 ubiquitin-conjugating enzyme E2 36 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 110810031 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
D 110815514 cell cycle checkpoint control protein RAD9A isoform X1 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 110813184 checkpoint protein hus1 K10903 HUS1; HUS1 checkpoint protein
D 110811581 uncharacterized protein LOC110811581 isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 110822135 cell cycle checkpoint protein RAD17 isoform X1 K06662 HRAD17; cell cycle checkpoint protein
D 110813509 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 110812802 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 110813508 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110807822 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110822243 uncharacterized protein LOC110822243 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D 110817085 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 110811581 uncharacterized protein LOC110811581 isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 110823092 LOW QUALITY PROTEIN: uncharacterized protein LOC110823092 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 110823773 protein TIPIN homolog isoform X1 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D 110814714 LOW QUALITY PROTEIN: uncharacterized protein LOC110814714 K11137 TELO2; telomere length regulation protein
D 110816868 uncharacterized protein LOC110816868 K20403 TTI1; TELO2-interacting protein 1
D 110819251 LOW QUALITY PROTEIN: uncharacterized protein At2g39910 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 110815643 large proline-rich protein bag6-A-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 110814675 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 110819078 LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 110812599 serine/threonine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 110812614 serine/threonine-protein kinase ATM-like isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 110810887 14-3-3-like protein D K06630 YWHAE; 14-3-3 protein epsilon
D 110814358 14-3-3-like protein GF14 kappa isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 110807257 LOW QUALITY PROTEIN: 14-3-3-like protein GF14 psi K06630 YWHAE; 14-3-3 protein epsilon
D 110816639 14-3-3 protein 7 isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 110816689 14-3-3-like protein isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 110825974 14-3-3-like protein B K06630 YWHAE; 14-3-3 protein epsilon
D 110822089 LOW QUALITY PROTEIN: 14-3-3 protein 7-like K06630 YWHAE; 14-3-3 protein epsilon
D 110821304 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 110807124 LOW QUALITY PROTEIN: uncharacterized protein LOC110807124 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 110809666 serine/threonine-protein kinase Nek1 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 110811738 serine/threonine-protein kinase Nek6 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 110811802 serine/threonine-protein kinase Nek6 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 110817305 LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek5 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 110814726 serine/threonine-protein kinase Nek4-like K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 110806390 uncharacterized protein LOC110806390 K22422 DONSON; protein downstream neighbor of Son
D 110817269 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110811000 protein SDE2 homolog K25059 SDE2; replication stress response regulator SDE2
D 110808484 protein DECREASED SIZE EXCLUSION LIMIT 1 K24770 DSE1; protein decreased size exclusion limit 1
B Other factors with a suspected DNA repair function
C DNA polymerases
D 110819055 uncharacterized protein LOC110819055 K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 110810386 DNA-directed primase/polymerase protein isoform X1 K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 110826172 DNA cross-link repair 1A protein-like isoform X1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D 110812974 DNA cross-link repair protein SNM1 isoform X1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D 110816133 5' exonuclease Apollo isoform X1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D 110819652 5' exonuclease Apollo K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 110808545 exonuclease V, chloroplastic K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 110808235 endonuclease V isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 110817904 endonuclease 1 isoform X1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D 110817865 endonuclease 4-like K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D 110811937 LOW QUALITY PROTEIN: switch 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 110815857 pre-mRNA-processing factor 19 homolog 1-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 110825983 LOW QUALITY PROTEIN: cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 110823422 pre-mRNA-splicing factor SPF27 homolog K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 110819913 protein pleiotropic regulatory locus 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 110816701 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110812918 LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 110807447 ribonucleoside-diphosphate reductase small chain C K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 110819935 ribonucleoside-diphosphate reductase small chain A-like isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 110817579 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 110824350 uracil-DNA glycosylase, mitochondrial-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110826000 uracil-DNA glycosylase, mitochondrial-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110825944 probable DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E 110822216 DNA-3-methyladenine glycosylase 1 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E 110811734 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 110821733 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 110808490 uncharacterized protein LOC110808490 isoform X1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110813605 uncharacterized protein LOC110813605 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110815612 uncharacterized protein LOC110815612 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110814977 LOW QUALITY PROTEIN: uncharacterized protein LOC110814977 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110821052 uncharacterized protein LOC110821052 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110824104 uncharacterized protein LOC110824104 isoform X1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E 110807569 formamidopyrimidine-DNA glycosylase isoform X1 K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E 110816850 putative DNA glycosylase At3g47830 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 110809474 DNA-(apurinic or apyrimidinic site) lyase, chloroplastic isoform X1 K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
D DNA polymerase I
E 110810898 LOW QUALITY PROTEIN: DNA polymerase I A, chloroplastic/mitochondrial K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E 110810898 LOW QUALITY PROTEIN: DNA polymerase I A, chloroplastic/mitochondrial K02335 polA; DNA polymerase I [EC:2.7.7.7]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F 5878339 rpoB; RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F 5878449 rpoC2; RNA polymerase beta'' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F 5878388 rpoC1; RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F 5878374 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 110817855 uncharacterized protein LOC110817855 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 110820318 uncharacterized protein LOC110820318 isoform X1 K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E 110813840 DNA repair protein recA homolog 3, mitochondrial K03553 recA; recombination protein RecA
E 110821096 DNA repair protein recA homolog 1, chloroplastic isoform X1 K03553 recA; recombination protein RecA
D RecFOR pathway proteins
E 110813840 DNA repair protein recA homolog 3, mitochondrial K03553 recA; recombination protein RecA
E 110821096 DNA repair protein recA homolog 1, chloroplastic isoform X1 K03553 recA; recombination protein RecA
E 110818357 uncharacterized protein LOC110818357 isoform X1 K04485 radA; DNA repair protein RadA/Sms
E 110813465 ATP-dependent DNA helicase homolog RECG, chloroplastic isoform X1 K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F 110822750 DNA gyrase subunit B, chloroplastic/mitochondrial K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 110813840 DNA repair protein recA homolog 3, mitochondrial K03553 recA; recombination protein RecA
D 110821096 DNA repair protein recA homolog 1, chloroplastic isoform X1 K03553 recA; recombination protein RecA
D 110820318 uncharacterized protein LOC110820318 isoform X1 K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 110816701 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024