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Mitochondrial Biogenesis - Chaetura pelagica (chimney swift)
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
C Cytochrome c oxidase
C F-type ATPase
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D 104392442 POLRMT; DNA-directed RNA polymerase, mitochondrial K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
D 104387630 TFAM; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
D 104388475 TFB1M; dimethyladenosine transferase 1, mitochondrial isoform X1 K15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]
D 104394959 TFB2M; dimethyladenosine transferase 2, mitochondrial K17653 TFB2M; dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-]
C Mitochondrial translation factors
D 104394932 MTIF2; translation initiation factor IF-2, mitochondrial K02519 infB; translation initiation factor IF-2
D 104395887 MTIF3; translation initiation factor IF-3, mitochondrial K02520 infC; translation initiation factor IF-3
D 104396522 GFM2; ribosome-releasing factor 2, mitochondrial K02355 fusA; elongation factor G
D 104387043 GFM1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 104396006 MTERF2; transcription termination factor 2, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 104396653 MTERF3; transcription termination factor 3, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 104396267 GUF1; translation factor GUF1, mitochondrial K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D 104396659 POP1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 104388582 POP4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 104390897 RPP30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 104385363 RPP25L; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 104391985 RPP25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 104394066 RPP38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 104391646 RPP40; ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
D 104384957 TRMT10C; mitochondrial ribonuclease P protein 1 K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D 104385411 KIAA0391; mitochondrial ribonuclease P protein 3 K17655 MRPP3; mitochondrial ribonuclease P protein 3
C Other mitochondrial DNA transcription and translation factors
D 104385286 PTCD1; LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
D 104396539 PTCD2; pentatricopeptide repeat-containing protein 2, mitochondrial K17711 PTCD2; pentatricopeptide repeat domain-containing protein 2
D 104391057 PTCD3; pentatricopeptide repeat domain-containing protein 3, mitochondrial K17659 PTCD3; pentatricopeptide repeat domain-containing protein 3
D 104398435 DHX30; putative ATP-dependent RNA helicase DHX30 K13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]
D 104390260 ubiquinol-cytochrome-c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 104394713 LACE1; lactation elevated protein 1 K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D 104396465 XRCC6BP1; mitochondrial inner membrane protease ATP23 homolog K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D 104386283 SUPV3L1; ATP-dependent RNA helicase SUPV3L1, mitochondrial K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D 104386920 LACTB2; beta-lactamase-like protein 2 K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D 104391843 SLC25A6; ADP/ATP translocase 3 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 104388358 SLC25A5; ADP/ATP translocase 2 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 104393008 SLC25A4; ADP/ATP translocase 1 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 104398821 SLC25A31; LOW QUALITY PROTEIN: ADP/ATP translocase 4 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 104390852 SLC25A28; mitoferrin-2 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 104397219 SLC25A37; mitoferrin-1 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 104397651 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1 K25803 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1
D 104397360 ERAL1; GTPase Era, mitochondrial K03595 era; GTPase
D 104391349 YARS; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 104398155 YARS2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 104385622 LARS2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104391900 LARS; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104386120 DARS2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 104388468 GARS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 104392620 RARS; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 104394294 QRSL1; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D 104387261 GATB; glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D 104395184 GATC; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D 104397104 MTPAP; poly(A) RNA polymerase, mitochondrial K18060 MTPAP; poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19]
D 104385123 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
D 104384984 NSUN3; putative methyltransferase NSUN3 K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 104396789 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
D 104398068 RPUSD4; RNA pseudouridylate synthase domain-containing protein 4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
D 104396255 WBSCR16; Williams-Beuren syndrome chromosomal region 16 protein K23495 RCC1L; RCC1-like G exchanging factor-like protein
D 104391450 TRUB2; probable tRNA pseudouridine synthase 2 K23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]
D 104387530 FASTKD1; FAST kinase domain-containing protein 1 K27754 FASTKD1; FAST kinase domain-containing protein 1
D 104397417 FASTKD2; FAST kinase domain-containing protein 2 K18190 FASTKD2; FAST kinase domain-containing protein 2
D 104398260 FASTKD3; FAST kinase domain-containing protein 3 K27755 FASTKD3; FAST kinase domain-containing protein 3
D 104387184 TBRG4; protein TBRG4 K27756 TBRG4; FAST kinase domain-containing protein 4
D 104390652 FASTKD5; FAST kinase domain-containing protein 5 K27757 FASTKD5; FAST kinase domain-containing protein 5
D 104388926 probable peptide chain release factor C12orf65 homolog, mitochondrial K23498 COXPD7; peptide chain release factor
D 104390768 RMND1; required for meiotic nuclear division protein 1 homolog K23499 RMND1; required for meiotic nuclear division protein 1
D 104398420 GRSF1; G-rich sequence factor 1 K24984 GRSF1; G-rich sequence factor 1
D 104394646 METTL15; probable methyltransferase-like protein 15 K25876 METTL15; 12S rRNA N4-methylcytidine (m4C) methyltransferase [EC:2.1.1.-]
D 104394283 uncharacterized protein C6orf203 homolog K26186 MTRES1; mitochondrial transcription rescue factor 1
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D 104394464 POLG; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 104393306 POLG2; DNA polymerase subunit gamma-2, mitochondrial K02333 POLG2; DNA polymerase gamma 2
D 104393045 PRIMPOL; DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D 104389942 ENDOG; endonuclease G, mitochondrial K01173 ENDOG; endonuclease G, mitochondrial
D 104395298 MGME1; mitochondrial genome maintenance exonuclease 1 K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D 104396198 EXOG; nuclease EXOG, mitochondrial K15050 EXOG; nuclease EXOG, mitochondrial
D 104390951 twinkle protein, mitochondrial K17680 PEO1; twinkle protein [EC:5.6.2.3]
D 104396825 PIF1; ATP-dependent DNA helicase PIF1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
D 104395478 ATAD3A; LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 3A K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
D 104397172 ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D 104388577 DNAJA2; dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D 104389747 TOMM34; mitochondrial import receptor subunit TOM34 K17766 TOM34; mitochondrial import receptor subunit TOM34
D 104393300 RHOT1; mitochondrial Rho GTPase 1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 104386412 HSPA8; heat shock cognate 71 kDa protein isoform X1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 104397778 AIP; AH receptor-interacting protein K17767 AIP; AH receptor-interacting protein
D 104388329 aryl-hydrocarbon-interacting protein-like 1 K17767 AIP; AH receptor-interacting protein
B Outer membrane
C Transporter outer membrane (TOM) complex
D 104388501 TOMM40L; mitochondrial import receptor subunit TOM40B K11518 TOM40; mitochondrial import receptor subunit TOM40
D 104384996 TOMM70A; mitochondrial import receptor subunit TOM70 K17768 TOM70; mitochondrial import receptor subunit TOM70
D 104396201 TOMM22; mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D 104394909 TOMM20; mitochondrial import receptor subunit TOM20 homolog K17770 TOM20; mitochondrial import receptor subunit TOM20
D 104397163 TOMM6; mitochondrial import receptor subunit TOM6 homolog K17772 TOM6; mitochondrial import receptor subunit TOM6
C TOB/SAM complex
D 104395099 SAMM50; sorting and assembly machinery component 50 homolog K07277 SAM50; outer membrane protein insertion porin family
C Porin
D 104386851 VDAC1; voltage-dependent anion-selective channel protein 1 K05862 VDAC1; voltage-dependent anion channel protein 1
D 104391451 VDAC2; voltage-dependent anion-selective channel protein 2 isoform X1 K15040 VDAC2; voltage-dependent anion channel protein 2
D 104384853 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1 K15041 VDAC3; voltage-dependent anion channel protein 3
C ERMES complex
C Other outer membrane factor
D 104395689 MTX3; LOW QUALITY PROTEIN: metaxin-3 K17776 MTX; metaxin
D 104387403 MTX1; metaxin-1 K17776 MTX; metaxin
D 104387545 MTX2; metaxin-2 K17776 MTX; metaxin
D 104398950 MYO19; unconventional myosin-XIX K25838 MYO19; myosin XIX
D 104386232 mitochondrial amidoxime reducing component 2-like K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D 104386485 TIMM9; mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
C TIM8/13 complex
D 104397328 TIMM13; mitochondrial import inner membrane translocase subunit Tim13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D 104390204 CHCHD4; mitochondrial intermembrane space import and assembly protein 40 K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D 104386188 GFER; FAD-linked sulfhydryl oxidase ALR K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D 104387105 MINOS1; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 104391056 IMMT; LOW QUALITY PROTEIN: MICOS complex subunit MIC60 K17785 IMMT; MICOS complex subunit MIC60
D 104397512 protein QIL1 K24624 MICOS13; MICOS complex subunit MIC13
D 104389147 CHCHD3; MICOS complex subunit MIC19 isoform X1 K17563 CHCHD3; MICOS complex subunit MIC19
D 104390199 CHCHD6; MICOS complex subunit MIC25 K17564 CHCHD6; MICOS complex subunit MIC25
D 104389497 APOO; apolipoprotein O K24625 APOO; MICOS complex subunit MIC26
D 104387814 APOOL; MICOS complex subunit MIC27 K24626 APOOL; MICOS complex subunit MIC27
C MICOS complex (yeast)
D 104387105 MINOS1; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 104391056 IMMT; LOW QUALITY PROTEIN: MICOS complex subunit MIC60 K17785 IMMT; MICOS complex subunit MIC60
C TIM22 complex
D 104384826 TIMM22; mitochondrial import inner membrane translocase subunit Tim22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D 104391791 mitochondrial import inner membrane translocase subunit Tim23 K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D 104385580 TIMM17A; mitochondrial import inner membrane translocase subunit Tim17-A K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 104398690 TIMM21; mitochondrial import inner membrane translocase subunit Tim21 K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
C Mitochondrial calcium uniporter complex
D 104387624 MCU; calcium uniporter protein, mitochondrial K20858 MCU; calcium uniporter protein, mitochondrial
D 104387615 MICU1; calcium uptake protein 1, mitochondrial isoform X1 K22827 MICU1; calcium uptake protein 1, mitochondrial
D 104390333 MICU2; calcium uptake protein 2, mitochondrial K22828 MICU2; calcium uptake protein 2, mitochondrial
D 104394507 CCDC109B; mitochondrial calcium uniporter regulatory subunit MCUb K22829 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial
D 104387607 SMDT1; essential MCU regulator, mitochondrial K22830 SMDT1; essential MCU regulator, mitochondrial
D 104391670 MCUR1; mitochondrial calcium uniporter regulator 1 K22137 MCUR1; mitochondrial calcium uniporter regulator 1
C Other inner membrane factors
D 104391024 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D 104394635 IMMP1L; mitochondrial inner membrane protease subunit 1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D 104396429 IMMP2L; mitochondrial inner membrane protease subunit 2 K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D 104393086 TMEM126A; transmembrane protein 126A K18157 TMEM126A; transmembrane protein 126A
D 104386970 MPC1; mitochondrial pyruvate carrier 1 K22138 MPC1; mitochondrial pyruvate carrier 1
D 104395745 MPC2; mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
B Matrix
C MMC/PAM proteins
D 104394859 TIMM44; mitochondrial import inner membrane translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D 104390600 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 104392638 GRPEL2; grpE protein homolog 2, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 104393635 GRPEL1; grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 104390835 DNAJC19; mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
D 104397817 PAM16; mitochondrial import inner membrane translocase subunit TIM16 K17805 PAM16; mitochondrial import inner membrane translocase subunit TIM16
C Other matrix factors
D 104389897 PMPCA; mitochondrial-processing peptidase subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D 104394573 PMPCB; mitochondrial-processing peptidase subunit beta K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D 104392500 MIPEP; mitochondrial intermediate peptidase K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D 104397403 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D 104397402 HSPE1; 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
D 104384932 DNAJA3; dnaJ homolog subfamily A member 3, mitochondrial K09504 DNAJA3; DnaJ homolog subfamily A member 3
D 104398703 TAMM41; phosphatidate cytidylyltransferase, mitochondrial K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D 104389893 DNLZ; DNL-type zinc finger protein K17808 ZIM17; mitochondrial protein import protein ZIM17
D 104386510 POLDIP2; polymerase delta-interacting protein 2 K17809 POLDIP2; polymerase delta-interacting protein 2
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D 104397373 CREB1; cyclic AMP-responsive element-binding protein 1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 104396522 GFM2; ribosome-releasing factor 2, mitochondrial K02355 fusA; elongation factor G
D 104387043 GFM1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 104397440 SP1; transcription factor Sp1 K04684 SP1; transcription factor Sp1
D 104389076 YY1; transcriptional repressor protein YY1 K09201 YY; transcription factor YY
D 104394813 GABPB2; GA-binding protein subunit beta-2 K09454 GABPB; GA-binding protein transcription factor, beta
D 104385940 GABPB1; GA-binding protein subunit beta-1 isoform X1 K09454 GABPB; GA-binding protein transcription factor, beta
D 104387630 TFAM; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
C Nuclear respiratory factors
D 104387564 NRF1; nuclear respiratory factor 1 K11831 NRF1; nuclear respiratory factor 1
D 104387411 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
C Coactivators
D 104397341 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
D 104392634 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
D 104390941 PPRC1; LOW QUALITY PROTEIN: peroxisome proliferator-activated receptor gamma coactivator-related protein 1 K17963 PPRC1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1
D 104386459 CRTC1; CREB-regulated transcription coactivator 1 K15309 CRTC1; CREB-regulated transcription coactivator 1
D 104386837 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 104387577 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C Proteins involved in Fe-S cluster biogenesis
D 104388214 NFS1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 104391647 LYRM4; LYR motif-containing protein 4 K22069 LYRM4; LYR motif-containing protein 4
D 104398382 FXN; frataxin, mitochondrial K19054 FXN; frataxin [EC:1.16.3.1]
D 104390324 FDX1; adrenodoxin, mitochondrial K22070 FDX1; ferredoxin-1, mitochondrial
D 104387847 adrenodoxin-like K22071 FDX2; ferredoxin-2, mitochondrial
D 104393259 FDXR; NADPH:adrenodoxin oxidoreductase, mitochondrial K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D 104390600 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 104388059 HSCB; iron-sulfur cluster co-chaperone protein HscB, mitochondrial K04082 hscB; molecular chaperone HscB
D 104390751 SIL1; nucleotide exchange factor SIL1 K14001 SIL1; nucleotide exchange factor SIL1
D 104394206 GLRX5; glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
D 104386807 ISCA1; iron-sulfur cluster assembly 1 homolog, mitochondrial K22063 ISCA1; iron-sulfur cluster assembly 1
D 104385429 ISCA2; iron-sulfur cluster assembly 2 homolog, mitochondrial K22072 ISCA2; iron-sulfur cluster assembly 2
D 104386113 IBA57; putative transferase CAF17, mitochondrial K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D 104390247 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D 104394354 BOLA3; bolA-like protein 3 K22075 BOLA3; BolA-like protein 3
D 104390877 SFXN3; sideroflexin-3 K23500 SFXN1_3; sideroflexin-1/3
D 104392565 SFXN1; sideroflexin-1 K23500 SFXN1_3; sideroflexin-1/3
D 104390882 SFXN2; sideroflexin-2 K23501 SFXN2; sideroflexin-2
D 104392059 SFXN5; sideroflexin-5 K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D 104387650 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 104391942 DHTKD1; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
D 104396467 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
D 104396016 HCFC2; host cell factor 2 K27390 HCFC2; host cell factor 2
D 104391069 HTT; huntingtin K04533 HD; huntingtin
D 104385442 ESRRB; steroid hormone receptor ERR2 isoform X1 K08553 NR3B2; estrogen-related receptor beta
D 104386184 ESRRG; estrogen-related receptor gamma isoform X1 K08554 NR3B3; estrogen-related receptor gamma
D 104387706 NRIP1; nuclear receptor-interacting protein 1 K17965 NRIP1; nuclear receptor-interacting protein 1
D 104385189 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 104398615 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 104397314 LONP1; lon protease homolog, mitochondrial K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D 104386297 SIRT1; NAD-dependent protein deacetylase sirtuin-1 K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
D 104389532 SERAC1; protein SERAC1 K23504 SERAC1; protein SERAC1
D 104395551 PGC-1 and ERR-induced regulator in muscle protein 1-like K26738 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1
D 104393920 ES1 protein homolog, mitochondrial-like isoform X1 K27835 GATD3; glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial
D 104389161 ES1 protein homolog, mitochondrial K27835 GATD3; glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D 104390472 NDUFAF1; complex I intermediate-associated protein 30, mitochondrial K18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
D 104395676 NDUFAF2; mimitin, mitochondrial K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D 104396483 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 K18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
D 104390983 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D 104396650 NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
D 104394952 NDUFAF7; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D 104385242 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
D 104398719 ACAD9; acyl-CoA dehydrogenase family member 9, mitochondrial K15980 ACAD9; acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-]
D 104385463 NUBPL; iron-sulfur protein NUBPL K03593 mrp; ATP-binding protein involved in chromosome partitioning
D 104398061 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1 K18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1
D 104394285 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial K23164 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial
D 104395774 TIMMDC1; complex I assembly factor TIMMDC1, mitochondrial K23505 TIMMDC1; complex I assembly factor TIMMDC1
C Complex-II assembly factors
C Complex-III assembly factors
D 104387332 mitochondrial chaperone BCS1 K08900 BCS1; mitochondrial chaperone BCS1
D 104384825 TTC19; tetratricopeptide repeat protein 19, mitochondrial K18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial
D 104386640 LYRM7; LOW QUALITY PROTEIN: complex III assembly factor LYRM7 K18170 LYRM7; complex III assembly factor LYRM7
D 104390260 ubiquinol-cytochrome-c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 104397172 ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
D 104393113 protein CCSMST1 K27339 UQCC4; ubiquinol-cytochrome c reductase complex assembly factor 4
D 104387118 SMIM4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
D 104396080 uncharacterized protein C12orf73 homolog K27341 UQCC6; ubiquinol-cytochrome c reductase complex assembly factor 6
D 104398157 uncharacterized protein C7orf73 homolog K27319 STMP1; short transmembrane mitochondrial protein 1
C Complex-IV assembly factors
D 104397621 CMC1; COX assembly mitochondrial protein homolog K18171 CMC1; COX assembly mitochondrial protein 1
D 104396353 CMC2; COX assembly mitochondrial protein 2 homolog K18172 CMC2; COX assembly mitochondrial protein 2
D 104392163 cytochrome c oxidase assembly factor 1 homolog K18173 COA1; cytochrome c oxidase assembly factor 1
D 104390000 cytochrome c oxidase assembly factor 5 K18178 COA5; cytochrome c oxidase assembly factor 5
D 104385166 cytochrome c oxidase assembly factor 7 K18180 COA7; cytochrome c oxidase assembly factor 7
D 104398189 protoheme IX farnesyltransferase, mitochondrial K02257 COX10; heme o synthase [EC:2.5.1.141]
D 104393282 cytochrome c oxidase assembly protein COX11, mitochondrial K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D 104390921 cytochrome c oxidase assembly protein COX15 homolog K02259 COX15; heme a synthase [EC:1.17.99.9]
D 104389284 cytochrome c oxidase copper chaperone K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D 104394093 mitochondrial inner membrane protein COX18 K17797 COX18; mitochondrial inner membrane protein COX18
D 104394964 cytochrome c oxidase protein 20 homolog K18184 COX20; cytochrome c oxidase assembly protein subunit 20
D 104395297 PET117; protein PET117 homolog, mitochondrial K18188 PET117; protein PET117
D 104389911 SURF1; surfeit locus protein 1 K14998 SURF1; surfeit locus 1 family protein
D 104398198 protein SCO1 homolog, mitochondrial K07152 SCO1; protein SCO1
D 104395278 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial K17964 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial
D 104398116 APOPT1; apoptogenic protein 1, mitochondrial K23506 APOPT1; apoptogenic protein 1
D 104398157 uncharacterized protein C7orf73 homolog K27319 STMP1; short transmembrane mitochondrial protein 1
D 104387118 SMIM4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
C Complex-V assembly factors
D 104396680 ATPAF1; ATP synthase mitochondrial F1 complex assembly factor 1 K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
D 104394050 ATPAF2; ATP synthase mitochondrial F1 complex assembly factor 2 K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D 104386926 TMEM70; transmembrane protein 70, mitochondrial K17966 TMEM70; transmembrane protein 70, mitochondrial
D 104398101 6.8 kDa mitochondrial proteolipid K18193 MP68; 6.8 kDa mitochondrial proteolipid
D 104390887 USMG5; up-regulated during skeletal muscle growth protein 5 K18194 USMG5; up-regulated during skeletal muscle growth protein 5
B Mitochondrial dynamics
C Fission and Fusion factors
D 104390136 MFN1; mitofusin-1 K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
D 104395431 MFN2; mitofusin-2 K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D 104392339 OPA1; dynamin-like 120 kDa protein, mitochondrial K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
D 104387965 PARL; presenilins-associated rhomboid-like protein, mitochondrial K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 104397169 BAK1; bcl-2 homologous antagonist/killer K14021 BAK; Bcl-2 homologous antagonist/killer
D 104386587 DNM1L; dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 104397379 SUMO1; small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
D 104387953 SUMO3; small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
D 104393180 SUMO2; small ubiquitin-related modifier 2 K12160 SUMO; small ubiquitin-related modifier
D 104396736 SH3GLB1; endophilin-B1 K11248 SH3GLB1; endophilin-B1
D 104395867 mitochondrial carrier homolog 2-like K17885 MTCH; mitochondrial carrier
D 104392044 MTCH1; mitochondrial carrier homolog 1 K17885 MTCH; mitochondrial carrier
D 104392247 MFF; mitochondrial fission factor isoform X1 K22076 MFF; mitochondrial fission factor
D 104388248 FATE1; fetal and adult testis-expressed transcript protein K22076 MFF; mitochondrial fission factor
D 104389655 GDAP1L1; ganglioside-induced differentiation-associated protein 1-like 1 isoform X1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 104386927 GDAP1; ganglioside-induced differentiation-associated protein 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 104385684 VAT1; synaptic vesicle membrane protein VAT-1 homolog K23167 VAT1; synaptic vesicle membrane protein VAT-1
D 104394045 MIEF2; mitochondrial dynamics protein MID49 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 104395127 MIEF1; mitochondrial dynamics protein MID51 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 104385292 PLD6; mitochondrial cardiolipin hydrolase K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D 104389850 FAM73B; protein FAM73B K27289 MIGA; mitoguardin
D 104396718 FAM73A; protein FAM73A K27289 MIGA; mitoguardin
C Actin cytoskeleton organization
D 104385255 ACTB; actin, cytoplasmic 1 isoform X1 K05692 ACTB_G1; actin beta/gamma 1
D 104391979 ACTL9; actin-like protein 9 isoform X1 K05692 ACTB_G1; actin beta/gamma 1
D 104393236 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
D 104395894 NAA20; N-alpha-acetyltransferase 20 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D 104388004 NAA25; N-alpha-acetyltransferase 25, NatB auxiliary subunit K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D 104394811 PHB; prohibitin K17080 PHB1; prohibitin 1
D 104389845 PHB2; prohibitin-2 K17081 PHB2; prohibitin 2
D 104387667 KTN1; LOW QUALITY PROTEIN: kinectin K17975 KTN1; kinectin
C Retention of mitochondria
D 104386587 DNM1L; dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 104386011 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
D 104386012 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
D 104398395 MYO5B; LOW QUALITY PROTEIN: unconventional myosin-Vb K10357 MYO5; myosin V
D 104388277 XIAP; E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 104389450 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
C Morphogenesis factors
D 104393010 SNX25; sorting nexin-25 K17887 SNX25; sorting nexin-25
D 104393300 RHOT1; mitochondrial Rho GTPase 1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 104391056 IMMT; LOW QUALITY PROTEIN: MICOS complex subunit MIC60 K17785 IMMT; MICOS complex subunit MIC60
D 104385901 NEDD4; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase NEDD4 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
D 104396613 OXR1; oxidation resistance protein 1 isoform X1 K25437 OXR1; oxidation resistance protein 1
B Mitophagy factors
C Autophagy-related proteins
D 104389072 ATG2B; autophagy-related protein 2 homolog B K17906 ATG2; autophagy-related protein 2
D 104389303 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D 104387951 ATG4B; cysteine protease ATG4B K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 104397942 ATG4C; cysteine protease ATG4C K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 104388373 ATG4A; cysteine protease ATG4A K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 104394287 ATG5; autophagy protein 5 isoform X1 K08339 ATG5; autophagy-related protein 5
D 104385648 BECN1; beclin-1 K08334 BECN; beclin
D 104398712 ATG7; ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D 104394540 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
D 104385223 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
D 104387339 ATG9A; autophagy-related protein 9A K17907 ATG9; autophagy-related protein 9
D 104398311 ATG10; ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D 104387692 ATG14; beclin 1-associated autophagy-related key regulator K17889 ATG14L; beclin 1-associated autophagy-related key regulator
D 104385105 ATG16L1; autophagy-related protein 16-1 isoform X1 K17890 ATG16L1; autophagy-related protein 16-1
D 104385279 WIPI2; WD repeat domain phosphoinositide-interacting protein 2 K17908 WIPI1_2; autophagy-related protein 18
D 104393318 WIPI1; WD repeat domain phosphoinositide-interacting protein 1 K17908 WIPI1_2; autophagy-related protein 18
D 104395818 vacuolar protein 8-like K08332 VAC8; vacuolar protein 8
C Parkin-dependent mechanism factors
D 104390821 PARK2; E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 104385230 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 104393765 CLEC16A; protein CLEC16A K19513 CLEC16A; protein CLEC16A
D 104395513 PINK1; serine/threonine-protein kinase PINK1, mitochondrial K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
D 104387965 PARL; presenilins-associated rhomboid-like protein, mitochondrial K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 104386491 SQSTM1; sequestosome-1 K14381 SQSTM1; sequestosome 1
D 104397561 TAX1BP1; tax1-binding protein 1 isoform X1 K21347 TAX1BP1; Tax1-binding protein 1
D 104398456 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2 K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
D 104390456 AMBRA1; LOW QUALITY PROTEIN: activating molecule in BECN1-regulated autophagy protein 1 K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
C Parkin-independent mechanism factors
D 104390416 ATG13; autophagy-related protein 13 isoform X1 K08331 ATG13; autophagy-related protein 13
D 104388726 ULK1; serine/threonine-protein kinase ULK1 K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
D 104398917 ULK2; serine/threonine-protein kinase ULK2 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D 104396904 RB1CC1; RB1-inducible coiled-coil protein 1 K17589 RB1CC1; RB1-inducible coiled-coil protein 1
D 104389057 HSP90AA1; heat shock protein HSP 90-alpha K04079 HSP90A; molecular chaperone HtpG
D 104396256 HSP90AB1; LOW QUALITY PROTEIN: heat shock protein HSP 90-beta K04079 HSP90A; molecular chaperone HtpG
D 104396074 CDC37; hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
D 104385284 SMURF1; E3 ubiquitin-protein ligase SMURF1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 104393216 SMURF2; E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 104386400 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
D 104389140 FUNDC1; FUN14 domain-containing protein 1 K17986 FUNDC1; FUN14 domain-containing protein 1
C Other mitophagy factors
D 104385189 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 104398615 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 104394966 MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C K10435 MAP1LC; microtubule-associated protein 1 light chain
D 104390263 LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3A-like K10435 MAP1LC; microtubule-associated protein 1 light chain
D 104391764 MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B K10435 MAP1LC; microtubule-associated protein 1 light chain
D 104398141 microtubule-associated proteins 1A/1B light chain 3C-like K10435 MAP1LC; microtubule-associated protein 1 light chain
D 104385644 NBR1; next to BRCA1 gene 1 protein K17987 NBR1; next to BRCA1 gene 1 protein
D 104393741 TECPR1; tectonin beta-propeller repeat-containing protein 1 K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
D 104390573 ZFYVE1; zinc finger FYVE domain-containing protein 1 isoform X1 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 104385700 COASY; bifunctional coenzyme A synthase K02318 COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
D 104393820 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
D 104388607 protein C19orf12 homolog K23168 MPAN; protein MPAN
D 104388327 FUNDC2; FUN14 domain-containing protein 2 K24308 FUNDC2; FUN14 domain-containing protein 2
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 9, 2024