+C GAG KO
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Glycosaminoglycan Binding Proteins - Crocodylus porosus (Australian saltwater crocodile)
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AHeparan sulfate / Heparin
B Cytokines
C 109313276 interleukin-1 beta-like K04519 IL1B; interleukin 1 beta
C 109317713 IL10; interleukin-10 K05443 IL10; interleukin 10
C 109310277 IL12B; interleukin-12 subunit beta K05425 IL12B; interleukin 12B
C 109315524 IFNG; interferon gamma K04687 IFNG; interferon gamma
B Chemokines
C ------ CCL12; C-C motif chemokine 12 [MMU:20293] [KO:K14624]
C 109309501 interleukin-8-like K10030 IL8; interleukin 8
C 109309502 interleukin-8-like K10030 IL8; interleukin 8
C 109309503 interleukin-8-like K10030 IL8; interleukin 8
C 109309504 interleukin-8-like K10030 IL8; interleukin 8
C 109309506 interleukin-8-like K10030 IL8; interleukin 8
C 109310294 alveolar macrophage chemotactic factor-like K10030 IL8; interleukin 8
C 109309480 C-X-C motif chemokine 10-like K12671 CXCL10; C-X-C motif chemokine 10
C 109309481 C-X-C motif chemokine 11-6-like K12671 CXCL10; C-X-C motif chemokine 10
C 109324021 CXCL12; stromal cell-derived factor 1 K10031 CXCL12; C-X-C motif chemokine 12
B Adhesion molecules of cell surface
C 109307129 SELE; E-selectin isoform X1 K06496 SELP; selectin, platelet
C 109318089 NCAM1; LOW QUALITY PROTEIN: neural cell adhesion molecule 1 K06491 NCAM; neural cell adhesion molecule
C 109305715 NCAM2; neural cell adhesion molecule 2 isoform X1 K06491 NCAM; neural cell adhesion molecule
C 109314977 PECAM1; platelet endothelial cell adhesion molecule isoform X1 K06471 PECAM1; platelet/endothelial cell adhesion molecule
B Morphogens
C 109323853 bone morphogenetic protein 2-like K21283 BMP2; bone morphogenetic protein 2
C 109319038 BMP2; bone morphogenetic protein 2 K21283 BMP2; bone morphogenetic protein 2
C 109320565 bone morphogenetic protein 2-like K21283 BMP2; bone morphogenetic protein 2
C 109324597 BMP4; bone morphogenetic protein 4 K04662 BMP4; bone morphogenetic protein 4
C 109318779 BMP7; bone morphogenetic protein 7 K16621 BMP7; bone morphogenetic protein 7
C 109306891 SHH; sonic hedgehog protein K11988 SHH; sonic hedgehog
C 109315624 WNT2; protein Wnt-2 isoform X1 K00182 WNT2; wingless-type MMTV integration site family, member 2
C 109317873 WNT2B; protein Wnt-2b K00182 WNT2; wingless-type MMTV integration site family, member 2
C 109322559 WNT3; proto-oncogene Wnt-3 K00312 WNT3; wingless-type MMTV integration site family, member 3
C 109306211 WNT3A; protein Wnt-3a K00312 WNT3; wingless-type MMTV integration site family, member 3
C 109314294 WNT4; protein Wnt-4 K00408 WNT4; wingless-type MMTV integration site family, member 4
C 109319028 protein Wnt-4-like K00408 WNT4; wingless-type MMTV integration site family, member 4
C 109315921 WNT5B; protein Wnt-5b K00444 WNT5; wingless-type MMTV integration site family, member 5
C 109311322 WNT5A; protein Wnt-5a K00444 WNT5; wingless-type MMTV integration site family, member 5
C 109316324 WNT7B; protein Wnt-7b K00572 WNT7; wingless-type MMTV integration site family, member 7
C 109311345 WNT7A; protein Wnt-7a K00572 WNT7; wingless-type MMTV integration site family, member 7
C 109310293 WNT8A; protein Wnt-8a K00714 WNT8; wingless-type MMTV integration site family, member 8
C 109323884 WNT8B; protein Wnt-8b K00714 WNT8; wingless-type MMTV integration site family, member 8
C 109323124 WNT9B; protein Wnt-9b K01064 WNT9; wingless-type MMTV integration site family, member 9
C 109306227 WNT9A; protein Wnt-9a isoform X1 K01064 WNT9; wingless-type MMTV integration site family, member 9
C 109310818 protein Wnt-11b-like K01384 WNT11; wingless-type MMTV integration site family, member 11
C 109306851 WNT11; protein Wnt-11 isoform X1 K01384 WNT11; wingless-type MMTV integration site family, member 11
C 109315638 WNT16; protein Wnt-16 K01558 WNT16; wingless-type MMTV integration site family, member 16
B Growth factors/receptors
C 109309312 AREG; amphiregulin K09782 AREG; amphiregulin
C 109310053 FGF1; fibroblast growth factor 1 isoform X1 K18496 FGF1; fibroblast growth factor 1
C 109309334 FGF2; fibroblast growth factor 2 K18497 FGF2; fibroblast growth factor 2
C 109307884 FGF10; fibroblast growth factor 10 K04358 FGF; fibroblast growth factor
C 109321606 FGF3; fibroblast growth factor 3 K04358 FGF; fibroblast growth factor
C 109321630 FGF4; fibroblast growth factor 4 isoform X1 K04358 FGF; fibroblast growth factor
C 109321893 FGF20; fibroblast growth factor 20 K04358 FGF; fibroblast growth factor
C 109309047 FGF7; fibroblast growth factor 7 K04358 FGF; fibroblast growth factor
C 109309314 FGF5; fibroblast growth factor 5 K04358 FGF; fibroblast growth factor
C 109316042 FGF6; fibroblast growth factor 6 K04358 FGF; fibroblast growth factor
C 109309941 FGF18; fibroblast growth factor 18 K04358 FGF; fibroblast growth factor
C 109317431 FGF17; fibroblast growth factor 17 isoform X1 K04358 FGF; fibroblast growth factor
C 109323829 FGF8; fibroblast growth factor 8 K04358 FGF; fibroblast growth factor
C 109312390 FGF22; fibroblast growth factor 22 K04358 FGF; fibroblast growth factor
C 109306671 FGF9; fibroblast growth factor 9 K04358 FGF; fibroblast growth factor
C 109313694 FGF16; fibroblast growth factor 16 K04358 FGF; fibroblast growth factor
C 109308557 FGF12; fibroblast growth factor 12 isoform X1 K22413 FGF11_12_13; fibroblast growth factor 11/12/13
C 109311019 FGF13; fibroblast growth factor 13 isoform X1 K22413 FGF11_12_13; fibroblast growth factor 11/12/13
C 109306359 FGF14; fibroblast growth factor 14 isoform X1 K23920 FGF14; fibroblast growth factor 14
C 109321645 FGF19; fibroblast growth factor 19 K22603 FGF19; fibroblast growth factor 19
C 109320829 FGF21; fibroblast growth factor 21 K22429 FGF21; fibroblast growth factor 21
C 109316272 FGF23; fibroblast growth factor 23 K22428 FGF23; fibroblast growth factor 23
C 109317416 FGFR1; fibroblast growth factor receptor 1 isoform X1 K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
C 109323987 FGFR2; fibroblast growth factor receptor 2 isoform X1 K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
C 109309909 HBEGF; proheparin-binding EGF-like growth factor isoform X1 K08523 HBEGF; heparin-binding EGF-like growth factor
C 109315770 HGF; hepatocyte growth factor isoform X1 K05460 HGF; hepatocyte growth factor
C 109320959 MDK; midkine K06828 MDK; midkine
C 109321161 IGF2; insulin-like growth factor II isoform X1 K13769 IGF2; insulin-like growth factor 2
C 109323609 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1 K05455 NRG1; neuregulin 1
C 109323986 HDGF; hepatoma-derived growth factor K16641 HDGF; hepatoma-derived growth factor
C 109314821 PDGFA; platelet-derived growth factor subunit A K04359 PDGFA; platelet-derived growth factor subunit A
C 109316689 PDGFB; platelet-derived growth factor subunit B K17386 PDGFB; platelet-derived growth factor subunit B
C 109319735 TGFB2; transforming growth factor beta-2 K13376 TGFB2; transforming growth factor beta-2
C 109316513 PTN; LOW QUALITY PROTEIN: pleiotrophin K16642 PTN; pleiotrophin
C 109319861 VEGFA; vascular endothelial growth factor A isoform X1 K05448 VEGFA; vascular endothelial growth factor A
B Extracellular matrix molecules
C 109309687 FGA; fibrinogen alpha chain K03903 FGA; fibrinogen alpha chain
C 109309686 FGB; fibrinogen beta chain K03904 FGB; fibrinogen beta chain
C 109309688 FGG; fibrinogen gamma chain K03905 FGG; fibrinogen gamma chain
C 109322680 FN1; fibronectin isoform X1 K05717 FN1; fibronectin 1
C 109309040 FBN1; fibrillin-1 isoform X1 K06825 FBN1; fibrillin 1
C 109323411 FBN2; fibrillin-2 isoform X1 K23342 FBN2_3; fibrillin 2/3
C 109320529 FBN3; fibrillin-3 K23342 FBN2_3; fibrillin 2/3
C ------ LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]
C 109313853 TNC; tenascin isoform X1 K06252 TN; tenascin
C 109307152 TNN; tenascin-N isoform X1 K06252 TN; tenascin
C 109307154 TNR; tenascin-R K06252 TN; tenascin
C 109320777 SMOC1; SPARC-related modular calcium-binding protein 1 K24354 SMOC; SPARC-related modular calcium-binding protein
C 109320025 SMOC2; SPARC-related modular calcium-binding protein 2 isoform X1 K24354 SMOC; SPARC-related modular calcium-binding protein
C 109320792 THBS1; thrombospondin-1 K16857 THBS1; thrombospondin 1
C 109307991 THBS4; thrombospondin-4 isoform X1 K04659 THBS2S; thrombospondin 2/3/4/5
C 109324699 THBS3; thrombospondin-3 K04659 THBS2S; thrombospondin 2/3/4/5
C 109312347 COMP; cartilage oligomeric matrix protein K04659 THBS2S; thrombospondin 2/3/4/5
C 109320024 THBS2; thrombospondin-2 isoform X1 K04659 THBS2S; thrombospondin 2/3/4/5
C 109317257 VTN; vitronectin isoform X1 K06251 VTN; vitronectin
C 109308897 COL1A2; collagen alpha-2(I) chain isoform X1 K06236 COL1A; collagen type I alpha
C 109323229 collagen alpha-1(II) chain-like K19719 COL2A; collagen type II alpha
C 109322710 COL3A1; collagen alpha-1(III) chain isoform X1 K19720 COL3A; collagen type III alpha
C 109308617 COL4A3; collagen alpha-3(IV) chain K06237 COL4A; collagen type IV alpha
C 109308618 COL4A4; collagen alpha-4(IV) chain K06237 COL4A; collagen type IV alpha
C 109305483 COL4A2; collagen alpha-2(IV) chain K06237 COL4A; collagen type IV alpha
C 109306319 COL4A1; collagen alpha-1(IV) chain K06237 COL4A; collagen type IV alpha
C 109313718 COL4A5; collagen alpha-5(IV) chain isoform X1 K06237 COL4A; collagen type IV alpha
C 109313720 COL4A6; collagen alpha-6(IV) chain isoform X1 K06237 COL4A; collagen type IV alpha
C 109322701 COL5A2; collagen alpha-2(V) chain isoform X1 K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109324656 COL5A3; collagen alpha-3(V) chain K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109313841 collagen alpha-1(I) chain-like K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109307229 COL11A1; collagen alpha-1(XI) chain isoform X1 K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109307329 COL24A1; collagen alpha-1(XXIV) chain isoform X1 K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109313864 COL27A1; collagen alpha-1(XXVII) chain K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109314132 collagen alpha-1(V) chain K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
C 109322648 COL6A3; collagen alpha-3(VI) chain isoform X1 K06238 COL6A; collagen type VI alpha
C 109322723 COL6A2; collagen alpha-2(VI) chain isoform X1 K06238 COL6A; collagen type VI alpha
C 109322751 COL6A1; collagen alpha-1(VI) chain K06238 COL6A; collagen type VI alpha
C 109311199 collagen alpha-6(VI) chain-like K06238 COL6A; collagen type VI alpha
C 109312475 COL13A1; collagen alpha-1(XIII) chain isoform X1 K16617 COL13A; collagen type XIII alpha
C 109322600 COL18A1; collagen alpha-1(XVIII) chain isoform X1 K06823 COL18A; collagen type XVIII alpha
C 109311777 COL19A1; collagen alpha-1(XIX) chain isoform X1 K24340 COL19A; collagen type XIX alpha
C 109309299 COL25A1; collagen alpha-1(XXV) chain K24356 COL25A; collagen type XXV alpha
C 109310366 COLQ; acetylcholinesterase collagenic tail peptide isoform X1 K26586 COLQ; acetylcholinesterase collagenic tail peptide
B Axon guidance molecules
C 109308158 EFNA5; ephrin-A5 isoform X1 K05462 EFNA; ephrin-A
C 109324696 EFNA3; ephrin-A3 K05462 EFNA; ephrin-A
C 109324698 EFNA1; ephrin-A1 K05462 EFNA; ephrin-A
C 109324793 EFNA4; ephrin-A4 K05462 EFNA; ephrin-A
C 109312310 EFNA2; ephrin-A2 isoform X1 K05462 EFNA; ephrin-A
C 109315174 NTN1; netrin-1 K06843 NTN1; netrin 1
C 109313400 NTN3; netrin-3 K06843 NTN1; netrin 1
C 109323832 SLIT1; slit homolog 1 protein K06838 SLIT1; slit 1
C 109322043 SLIT2; slit homolog 2 protein isoform X1 K06839 SLIT2; slit 2
C 109309954 SLIT3; slit homolog 3 protein isoform X1 K06850 SLIT3; slit 3
C ------ SEMA5A; semaphorin 5A [HSA:9037] [KO:K06841]
B Coagulation and fibrinolysis
C 109321079 F2; prothrombin K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
C 109306297 F10; coagulation factor X isoform X1 K01314 F10; coagulation factor X [EC:3.4.21.6]
C 109307145 SERPINC1; antithrombin-III K03911 SERPINC1; antithrombin III
C 109312797 SERPIND1; heparin cofactor 2 K03912 SERPIND1; heparin cofactor II
C 109308635 SERPINE2; glia-derived nexin isoform X1 K16643 SERPINE2; glia-derived nexin
C 109317392 PLAT; tissue-type plasminogen activator K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
C 109324282 PLAU; urokinase-type plasminogen activator K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
C 109323023 TFPI; tissue factor pathway inhibitor K03909 TFPI; tissue factor pathway inhibitor
C 109313292 carboxypeptidase inhibitor SmCI-like K03909 TFPI; tissue factor pathway inhibitor
B Enzymes
C 109321870 HPSE; heparanase K07964 HPSE; heparanase [EC:3.2.1.166]
C 109323842 HPSE2; inactive heparanase-2 K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
C 109315652 hyaluronidase-1-like K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109315653 hyaluronidase-4-like K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109315654 SPAM1; hyaluronidase PH-20 K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109318255 HYAL3; hyaluronidase-3 K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109318290 HYAL1; hyaluronidase-1 K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109318293 HYAL2; hyaluronidase-2 K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 109323269 LPL; lipoprotein lipase K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
C 109321975 SOD3; extracellular superoxide dismutase [Cu-Zn] K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
B Microbial pathogens
C ------ Dengue virus, envelope protein
C ------ Foot-and-mouth disease virus - type O, VP3
C ------ penetrin
C ------ Borrelia burgdorferi
C ------ Chlamydia trachomatis
C ------ Neisseria gonorrhoeae
C ------ Leishmania amazonensis
B Others
C 109309325 ANXA5; annexin A5 isoform X1 K16646 ANXA5; annexin A5
C 109315420 APOA5; apolipoprotein A-V K09025 APOA5; apolipoprotein A-V
C 109311606 APOB; apolipoprotein B-100 K14462 APOB; apolipoprotein B
C 109305731 APP; amyloid beta A4 protein isoform X1 K04520 APP; amyloid beta A4 protein
C 109312056 CTSB; cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 109320466 duodenase-1-like isoform X1 K01319 CTSG; cathepsin G [EC:3.4.21.20]
C 109317341 PRNP; major prion protein homolog K05634 PRNP; prion protein
C 109321505 SLC8A3; sodium/calcium exchanger 3 isoform X1 K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
C 109319456 SLC8A1; sodium/calcium exchanger 1 isoform X1 K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
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AHyaluronan
B Cell surface receptors
C 109322366 CD38; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
C 109321333 CD44; CD44 antigen K06256 CD44; CD44 antigen
C 109309967 HMMR; hyaluronan mediated motility receptor K06267 HMMR; hyaluronan-mediated motility receptor
C 109309593 TLR2; toll-like receptor 2 K10159 TLR2; toll-like receptor 2
C 109309681 toll-like receptor 2 type-2 K10159 TLR2; toll-like receptor 2
C 109313858 TLR4; toll-like receptor 4 isoform X1 K10160 TLR4; toll-like receptor 4
C 109317945 LAYN; layilin K10077 LAYN; layilin
C 109321108 LYVE1; lymphatic vessel endothelial hyaluronic acid receptor 1 K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
C 109318265 stabilin-1-like K19020 STAB1; stabilin-1
C 109316565 STAB2; stabilin-2 isoform X1 K19013 STAB2; stabilin-2
C 109309095 CEMIP; cell migration-inducing and hyaluronan-binding protein K19031 CEMIP; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
C 109308772 transmembrane protein 2-like K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
C 109323535 TMEM2; transmembrane protein 2 K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
B Extracellular matrix or blood plasma proteins
C 109309120 ACAN; LOW QUALITY PROTEIN: aggrecan core protein K06792 AGC1; aggrecan 1
C 109323921 BCAN; brevican core protein isoform X1 K06795 BCAN; brevican
C 109317020 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
C 109322648 COL6A3; collagen alpha-3(VI) chain isoform X1 K06238 COL6A; collagen type VI alpha
C 109322723 COL6A2; collagen alpha-2(VI) chain isoform X1 K06238 COL6A; collagen type VI alpha
C 109322751 COL6A1; collagen alpha-1(VI) chain K06238 COL6A; collagen type VI alpha
C 109311199 collagen alpha-6(VI) chain-like K06238 COL6A; collagen type VI alpha
C 109309687 FGA; fibrinogen alpha chain K03903 FGA; fibrinogen alpha chain
C 109309686 FGB; fibrinogen beta chain K03904 FGB; fibrinogen beta chain
C 109309688 FGG; fibrinogen gamma chain K03905 FGG; fibrinogen gamma chain
C 109324254 HABP2; hyaluronan-binding protein 2 K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
C 109308081 HAPLN1; hyaluronan and proteoglycan link protein 1 K06848 HAPLN1; hyaluronan and proteoglycan link protein 1
C 109323911 HAPLN2; hyaluronan and proteoglycan link protein 2 K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
C 109312331 HAPLN4; hyaluronan and proteoglycan link protein 4 K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
C 109305568 HPX; hemopexin K18977 HPX; hemopexin
C 109315817 ITIH2; inter-alpha-trypsin inhibitor heavy chain H2 K19015 ITIH2; inter-alpha-trypsin inhibitor heavy chain H2
C 109318280 inter-alpha-trypsin inhibitor heavy chain H3-like isoform X1 K24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3
C 109311806 IMPG1; interphotoreceptor matrix proteoglycan 1 K19016 IMPG1; interphotoreceptor matrix proteoglycan 1
C 109305644 IMPG2; interphotoreceptor matrix proteoglycan 2 isoform X1 K19017 IMPG2; interphotoreceptor matrix proteoglycan 2
C 109323145 TNFAIP6; tumor necrosis factor-inducible gene 6 protein K19018 TNFAIP6; tumor necrosis factor-inducible gene 6 protein
C 109308080 VCAN; versican core protein isoform X1 K06793 VCAN; versican core protein
B Intracellular proteins
C 109323386 HABP4; intracellular hyaluronan-binding protein 4 isoform X1 K19019 HABP4; intracellular hyaluronan-binding protein 4
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 22, 2023