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Mitochondrial Biogenesis - Cryptosporidium parvum
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
C Cytochrome c oxidase
C F-type ATPase
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
C Mitochondrial transcription factors
C Mitochondrial translation factors
C RNase MRP
D cgd3_2820 hypothetical protein K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D cgd3_800 POP4 like ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D cgd3_1620 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
C Other mitochondrial DNA transcription and translation factors
D cgd8_1210 mitochondrial ADP/ATP-transporter, integral membrane protein with 4 transmembrane domains K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D cgd2_1030 mitochondrial carrier protein K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D cgd6_2970 tyrosyl-tRNA synthetase (tyrosyl-tRNA ligase; TyrRS). class-I aaRS K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D cgd5_610 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D cgd8_1030 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D cgd5_4400 RIKEN cDNA 2610011N19 gen K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D cgd4_1850 Ccr4p. RNAse K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D cgd3_2760 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D cgd5_2190 Nuc1p like endonuclease G K01173 ENDOG; endonuclease G, mitochondrial
C Other Mitochondrial DNA replication factors
D cgd7_1410 AAA domain containing protein K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D cgd8_3770 DNAJ like chaperone K09503 DNAJA2; DnaJ homolog subfamily A member 2
D cgd2_20 heat shock 70 (HSP70) protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
B Outer membrane
C Transporter outer membrane (TOM) complex
D cgd1_2560 Tom40p like translocase K11518 TOM40; mitochondrial import receptor subunit TOM40
C TOB/SAM complex
D cgd2_770 hypothetical protein K07277 SAM50; outer membrane protein insertion porin family
C Porin
C ERMES complex
C Other outer membrane factor
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
C TIM8/13 complex
D cgd6_4450 hypothetical protein K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
C Mitochondrial intermembrane space assembly (MIA) complex
B Inner mambrane
C MICOS complex
C MICOS complex (yeast)
C TIM22 complex
C TIM23 complex
D cgd2_4140 mitochondrial import inner membrane translocase subunit tim17 K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D cgd8_3400 RNA polymerase II CTD/NL1 interacting protein like phosphatase K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
C Other inner membrane factors
D cgd5_1870 LETM1/MRS7 family protein with a transmembrane region at the N-terminus K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D cgd4_620 hypothetical protein K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
B Matrix
C MMC/PAM proteins
D cgd3_2930 possible mitochondrial import inner membrane, translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D cgd3_3440 heat shock protein HSP70, mitochondrial K04043 dnaK; molecular chaperone DnaK
D cgd5_3510 co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D cgd5_3520 chaperone'DNAj domain protein chaperone' K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D cgd7_2080 mitochondrial processing peptidase, insulinase like metalloprotease K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D cgd5_3400 mitochondrial processing peptidase beta subunit K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D cgd6_4970 Hsp60; GroEL-like chaperone (ATpase), predicted mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D cgd7_2400 chaperonin 10 Kd subunit K04078 groES; chaperonin GroES
D cgd2_1330 DNAJ protein K03686 dnaJ; molecular chaperone DnaJ
D cgd5_3660 hypothetical protein K17808 ZIM17; mitochondrial protein import protein ZIM17
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
C Nuclear respiratory factors
C Coactivators
C Proteins involved in Fe-S cluster biogenesis
D cgd4_3040 NifS-like protein; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D cgd6_1050 IscU-like NifU protein, iron-sulfur protein K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D cgd5_4320 frataxin like protein K19054 FXN; frataxin [EC:1.16.3.1]
D cgd6_3000 ferredoxin-like protein Fd1 K22071 FDX2; ferredoxin-2, mitochondrial
D cgd8_2710 NADPH:ferredoxin--NADP+ reductase with a rossman fold nucleotide binding domain and a 2Fe-2S ferredoxin domain K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D cgd3_3440 heat shock protein HSP70, mitochondrial K04043 dnaK; molecular chaperone DnaK
D cgd3_2810 DNAJ domain containing protein K04082 hscB; molecular chaperone HscB
C Other regulator of mitochondrial biogenesis
D cgd6_5060 Ser/Thr protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D cgd6_650 OSK4 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
C Complex-II assembly factors
C Complex-III assembly factors
C Complex-IV assembly factors
C Complex-V assembly factors
B Mitochondrial dynamics
C Fission and Fusion factors
D cgd2_3400 dynamin-related protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Actin cytoskeleton organization
D cgd1_2660 n-terminal acetyltransferase complex ard1 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
C Mitochondrial movement
D cgd7_4240 prohibitin domain protein K17080 PHB1; prohibitin 1
D cgd5_2320 prohibitin with PHB domain K17081 PHB2; prohibitin 2
C Retention of mitochondria
D cgd2_3400 dynamin-related protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D cgd7_4350 myosin'unconventional myosin fused to an RCC1 domain (unique)' K10357 MYO5; myosin V
C Morphogenesis factors
B Mitophagy factors
C Autophagy-related proteins
D cgd8_2630 APG10/ Aut1p like like autophagocytosis protein involved in vacuolar transport K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D cgd3_2920 possible peptidase family C54 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D cgd6_230 hypothetical protein K08334 BECN; beclin
D cgd4_40 APG7-like ubiquitin activating enzyme E1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D cgd7_3990 hypothetical protein K08341 GABARAP; GABA(A) receptor-associated protein
C Parkin-dependent mechanism factors
D cgd7_1150 hypothetical protein K19513 CLEC16A; protein CLEC16A
C Parkin-independent mechanism factors
D cgd3_3770 Hsp90 K04079 HSP90A; molecular chaperone HtpG
C Other mitophagy factors
D cgd6_5060 Ser/Thr protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D cgd6_650 OSK4 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024