+F Repair protein KO
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DNA Repair and Recombination Proteins - Coccidioides posadasii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CPC735_067080 methylated-DNA--protein-cysteine methyltransferase, putative K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CPC735_001840 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CPC735_013310 mismatch-specific thymine-DNA glycosylate family protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E CPC735_024320 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E CPC735_071440 HhH-GPD family base excision DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CPC735_059510 HhH-GPD family base excision DNA repair protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CPC735_052320 apurinic endonuclease family protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E CPC735_058050 DNA lyase Apn2, putative K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F CPC735_018400 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F CPC735_043650 DNA polymerase alpha subunit B family protein K02328 POLD2; DNA polymerase delta subunit 2
F CPC735_018230 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
F CPC735_023430 DNA polymerase delta, subunit 4 family protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F CPC735_046170 DNA polymerase epsilon, catalytic subunit A, putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F CPC735_001850 DNA polymerase epsilon subunit B family protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F CPC735_014150 Histone-like transcription factor and archaeal histone family protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E CPC735_069690 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E CPC735_057250 DNA-repair protein Rad2, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E CPC735_055100 ATP-dependent DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E CPC735_019960 Tyrosyl-DNA phosphodiesterase family protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E CPC735_018800 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CPC735_003410 DNA 3'-phosphatase family protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E CPC735_026310 Poly(ADP-ribose) polymerase domain containing protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F CPC735_050520 DNA repair protein Rad4 family protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CPC735_021680 DNA repair protein Rad4 family protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CPC735_027470 UV excision repair protein rhp23, putative K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F CPC735_027760 RING-box protein 1a, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CPC735_016890 Cullin family protein K10609 CUL4; cullin 4
F CPC735_060770 CPSF A subunit region family protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F CPC735_044300 hypothetical protein K15082 RAD7; DNA repair protein RAD7
F CPC735_044310 DNA repair protein RAD16, putative K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F CPC735_009320 DNA-directed RNA polymerase II largest subunit, putative K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F CPC735_041900 DNA-directed RNA polymerase II, putative K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F CPC735_068050 DNA-directed RNA polymerase II 45 kDa polypeptide, putative K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F CPC735_039980 RNA polymerase Rpb4 family protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F CPC735_008570 DNA-directed RNA polymerase subunit, putative K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F CPC735_069930 DNA-directed RNA polymerase subunit, putative K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F CPC735_074170 DNA-directed RNA polymerase II, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F CPC735_056030 RNA polymerase Rpb8 family protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F CPC735_054690 DNA-directed RNA polymerase II, putative K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F CPC735_066800 DNA-directed RNA polymerase subunit, putative K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F CPC735_044270 RNA polymerase Rpb3/Rpb11 dimerization domain containing protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F CPC735_048480 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F CPC735_027760 RING-box protein 1a, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CPC735_016890 Cullin family protein K10609 CUL4; cullin 4
F CPC735_060770 CPSF A subunit region family protein K10610 DDB1; DNA damage-binding protein 1
F CPC735_019880 WD domain, G-beta repeat containing protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F CPC735_041370 SNF2 family N-terminal domain containing protein K10841 ERCC6; DNA excision repair protein ERCC-6
D TFIIH complex
E CPC735_030040 DNA repair helicase, putative K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E CPC735_008330 DNA repair helicase rad15, putative K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E CPC735_048740 BSD domain containing protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E CPC735_028370 TFIIH basal transcription factor complex p47 subunit, putative K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E CPC735_015790 Transcription factor Tfb4 family protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E CPC735_062390 Transcription factor tfb2 family protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E CPC735_001440 REX1 DNA Repair family protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E CPC735_044430 serine/threonine protein kinase crk1, putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E CPC735_026600 hypothetical protein K06634 CCNH; cyclin H
E CPC735_060970 CDK-activating kinase assembly factor MAT1 family protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E CPC735_001830 replication factor-A protein 1 family protein K07466 RFA1; replication factor A1
E CPC735_059430 OB-fold nucleic acid binding domain containing protein K10739 RFA2; replication factor A2
D Other NER factors
E CPC735_028880 DNA repair protein K10847 XPA; DNA-repair protein complementing XP-A cells
E CPC735_002300 DNA repair protein rad10 containing protein K10849 ERCC1; DNA excision repair protein ERCC-1
E CPC735_024400 ERCC4 domain containing protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E CPC735_020770 XPG N-terminal domain containing protein K10846 ERCC5; DNA excision repair protein ERCC-5
E CPC735_055100 ATP-dependent DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CPC735_074100 HEAT repeat containing protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E CPC735_052430 Cullin family protein K03869 CUL3; cullin 3
E CPC735_023370 Skp1 family, tetramerization domain containing protein K03872 ELOC; elongin-C
E CPC735_054370 hypothetical protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CPC735_045850 DNA mismatch repair protein msh-2, putative K08735 MSH2; DNA mismatch repair protein MSH2
E CPC735_043880 DNA mismatch repair family protein K08736 MSH3; DNA mismatch repair protein MSH3
E CPC735_063470 MutS domain III family protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E CPC735_015910 DNA mismatch repair protein MutL family protein K08734 MLH1; DNA mismatch repair protein MLH1
E CPC735_068480 DNA mismatch repair protein MutL family protein K10858 PMS2; DNA mismatch repair protein PMS2
E CPC735_003100 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain containing protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E CPC735_018400 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E CPC735_043650 DNA polymerase alpha subunit B family protein K02328 POLD2; DNA polymerase delta subunit 2
E CPC735_018230 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E CPC735_023430 DNA polymerase delta, subunit 4 family protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E CPC735_001830 replication factor-A protein 1 family protein K07466 RFA1; replication factor A1
E CPC735_059430 OB-fold nucleic acid binding domain containing protein K10739 RFA2; replication factor A2
D RFC (replication factor C)
E CPC735_064960 BRCA1 C Terminus domain containing protein K10754 RFC1; replication factor C subunit 1
E CPC735_037260 activator 1 subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
E CPC735_043190 Activator 1 41 kDa subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
E CPC735_064940 Activator 1 38 kDa subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
E CPC735_028970 Activator 1 subunit 3, putative K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E CPC735_069690 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E CPC735_066620 XPG family protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E CPC735_055100 ATP-dependent DNA ligase, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CPC735_047260 WD domain, G-beta repeat containing protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E CPC735_022790 Double-strand break repair protein mus-23, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E CPC735_022790 Double-strand break repair protein mus-23, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E CPC735_019690 DNA repair protein rhp51, putative K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E CPC735_019690 DNA repair protein rhp51, putative K04482 RAD51; DNA repair protein RAD51
E CPC735_032700 hypothetical protein K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E CPC735_002810 recombination protein rad52 containing protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E CPC735_047630 DNA repair protein rhp54, putative K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E CPC735_009470 SNF2 family N-terminal domain containing protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E CPC735_053020 DNA helicase recq1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E CPC735_053020 DNA helicase recq1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CPC735_046950 DNA topoisomerase family protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CPC735_042720 hypothetical protein K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E CPC735_001830 replication factor-A protein 1 family protein K07466 RFA1; replication factor A1
E CPC735_059430 OB-fold nucleic acid binding domain containing protein K10739 RFA2; replication factor A2
D Protein phosphatase 4
E CPC735_027080 suppressor of Mek1, putative K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E CPC735_012070 SMC family, C-terminal domain containing protein K22803 SMC5; structural maintenance of chromosomes protein 5
E CPC735_044840 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E CPC735_061330 Nse1 non-SMC component of SMC5-6 complex family protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E CPC735_051280 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E CPC735_031970 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E CPC735_023210 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E CPC735_007820 ERCC4 domain containing protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E CPC735_013990 DSS1/SEM1 family protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E CPC735_009260 hypothetical protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E CPC735_030250 GIY-YIG catalytic domain containing protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E CPC735_007500 XPG family protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CPC735_049720 MRG family protein K11339 MORF4L1; mortality factor 4-like protein 1
E CPC735_047540 ATPase, AAA family protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E CPC735_070880 Zn-finger in Ran binding protein and others domain containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E CPC735_070650 DEAD/DEAH box helicase domain containing protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E CPC735_026950 ATP-dependent DNA helicase ii, 70 kDa subunit family protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E CPC735_046900 Ku70/Ku80 beta-barrel domain containing protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E CPC735_022790 Double-strand break repair protein mus-23, putative K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E CPC735_016310 DNA ligase I, ATP-dependent family protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E CPC735_029440 ATP dependent DNA ligase domain containing protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E CPC735_054950 hypothetical protein K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E CPC735_018800 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CPC735_069430 hypothetical protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E CPC735_012910 Endonuclease/Exonuclease/phosphatase family protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E CPC735_060760 hypothetical protein K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E CPC735_053020 DNA helicase recq1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CPC735_046950 DNA topoisomerase family protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CPC735_042720 hypothetical protein K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E CPC735_071260 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E CPC735_019690 DNA repair protein rhp51, putative K04482 RAD51; DNA repair protein RAD51
E CPC735_071710 hypothetical protein K11137 TELO2; telomere length regulation protein
E CPC735_016070 WD domain, G-beta repeat containing protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E CPC735_023690 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E CPC735_026630 WD domain, G-beta repeat containing protein K24752 WDR70; WD repeat-containing protein 70
E CPC735_047260 WD domain, G-beta repeat containing protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CPC735_031570 ImpB/MucB/SamB family protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D CPC735_049410 hypothetical protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D CPC735_021560 ImpB/MucB/SamB family protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D CPC735_052770 ImpB/MucB/SamB family protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D CPC735_058110 DNA polymerase zeta catalytic subunit, putative K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D CPC735_035880 Ubiquitin-conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D CPC735_018240 postreplication repair protein, putative K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CPC735_017040 SNF2 family N-terminal domain containing protein K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D CPC735_025860 SNF2 family N-terminal domain containing protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CPC735_048390 ubiquitin-conjugating enzyme spm2, putative K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D CPC735_024840 Ubiquitin-conjugating enzyme E2, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D CPC735_069690 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D CPC735_047400 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D CPC735_041260 Rad9 family protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D CPC735_012760 Hus1-like family protein K10903 HUS1; HUS1 checkpoint protein
D CPC735_056640 Repair protein Rad1/Rec1/Rad17 containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D CPC735_039530 hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D CPC735_037260 activator 1 subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
D CPC735_043190 Activator 1 41 kDa subunit, putative K10755 RFC2_4; replication factor C subunit 2/4
D CPC735_064940 Activator 1 38 kDa subunit, putative K10756 RFC3_5; replication factor C subunit 3/5
D CPC735_028970 Activator 1 subunit 3, putative K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D CPC735_056640 Repair protein Rad1/Rec1/Rad17 containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D CPC735_062360 Timeless protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D CPC735_061770 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D CPC735_067150 hypothetical protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D CPC735_071710 hypothetical protein K11137 TELO2; telomere length regulation protein
D CPC735_055070 HEAT repeat containing protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D CPC735_028860 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
D CPC735_037310 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D CPC735_061740 DNA repair protein, putative K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D CPC735_016910 Phosphatidylinositol 3- and 4-kinase family protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D CPC735_048120 kinase domain containing protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D CPC735_044400 kinase domain containing protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D CPC735_044060 Protein kinase domain containing protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D CPC735_052410 M-phase inducer phosphatase, putative K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D CPC735_072450 14-3-3 protein, putative K06630 YWHAE; 14-3-3 protein epsilon
D CPC735_001150 14-3-3 protein, putative K06630 YWHAE; 14-3-3 protein epsilon
D CPC735_054070 protein kinase, putative K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D CPC735_005630 Fork head domain containing protein K24664 FKH; forkhead protein FKH
D CPC735_046220 Vacuolar protein sorting-associated protein VPS4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
D CPC735_047830 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D CPC735_052390 DNA polymerase V family protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D CPC735_050220 DNA repair metallo-beta-lactamase family protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D CPC735_008220 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
D CPC735_072840 SNF2 family N-terminal domain containing protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D CPC735_017350 WD domain, G-beta repeat containing protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D CPC735_055380 myb family transcription factor K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D CPC735_003950 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D CPC735_014350 Pre-mRNA splicing protein prp5, putative K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D CPC735_070480 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CPC735_003070 Ribonucleoside-diphosphate reductase large chain, putative K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D CPC735_017260 ribonucleoside-diphosphate reductase small chain, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CPC735_067080 methylated-DNA--protein-cysteine methyltransferase, putative K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CPC735_001840 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CPC735_002970 HhH-GPD family base excision DNA repair protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CPC735_048520 Formamidopyrimidine-DNA glycosylase N-terminal domain containing protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CPC735_059510 HhH-GPD family base excision DNA repair protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CPC735_070480 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024