+F Repair protein KO
#
DNA Repair and Recombination Proteins - Corynebacterium simulans
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D WM42_1199 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D WM42_1000 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E WM42_0191 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E WM42_1423 DNA-3-methyladenine glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E WM42_1777 hhH-GPD superbase excision DNA repair family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E WM42_1156 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E WM42_0608 DNA repair helicase rad25 family protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D WM42_0349 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_1716 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_1315 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_2531 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D WM42_1199 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D WM42_1000 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D WM42_1283 2OG-Fe(II) oxygenase superfamily protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E WM42_0191 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E WM42_1423 DNA-3-methyladenine glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E WM42_1777 hhH-GPD superbase excision DNA repair family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E WM42_0528 methyladenine glycosylase family protein K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E WM42_2348 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E WM42_1558 formamidopyrimidine-DNA glycosylase H2TH domain protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E WM42_0568 formamidopyrimidine-DNA glycosylase H2TH domain protein K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E WM42_1156 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E WM42_0833 exodeoxyribonuclease III family protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E WM42_1720 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
E WM42_0249 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E WM42_2608 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E WM42_1016 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E WM42_2621 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E WM42_2615 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E WM42_0156 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E WM42_0564 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_0668 uvrD/REP helicase N-terminal domain protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_0671 uvrD/REP helicase N-terminal domain protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_2608 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E WM42_0249 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F WM42_0991 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F WM42_0990 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F WM42_0921 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F WM42_0170 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F WM42_0471 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E WM42_0433 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E WM42_0434 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E WM42_2306 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E WM42_1441 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E WM42_2093 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E WM42_1131 ATPase associated with various cellular activities family protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E WM42_0250 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E WM42_1188 putative dNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E WM42_2316 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E WM42_1193 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E WM42_0249 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E WM42_0564 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_0668 uvrD/REP helicase N-terminal domain protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_0671 uvrD/REP helicase N-terminal domain protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E WM42_2011 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E WM42_1570 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E WM42_1958 single-strand binding family protein K03111 ssb; single-strand DNA-binding protein
E WM42_2097 dpnM; modification methylase DpnIIA K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E WM42_2451 recA; protein RecA K03553 recA; recombination protein RecA
E WM42_2564 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E WM42_2565 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E WM42_2563 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E WM42_0166 putative dNA replication factor Y K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E WM42_2451 recA; protein RecA K03553 recA; recombination protein RecA
E WM42_1780 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E WM42_1440 recF; DNA replication and repair RecF family protein K03629 recF; DNA replication and repair protein RecF
E WM42_0189 helicase domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E WM42_1631 divergent AAA domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E WM42_1498 divergent AAA domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E WM42_2139 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E WM42_1191 recR; recombination protein RecR K06187 recR; recombination protein RecR
E WM42_0019 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E WM42_2564 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E WM42_2565 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E WM42_2563 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E WM42_1517 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F WM42_1432 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F WM42_1438 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F WM42_1134 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F WM42_2139 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F WM42_1191 recR; recombination protein RecR K06187 recR; recombination protein RecR
F WM42_0249 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F WM42_1016 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F WM42_2621 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F WM42_2615 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D WM42_2297 impB/mucB/samB family protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D WM42_2451 recA; protein RecA K03553 recA; recombination protein RecA
D WM42_2470 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D WM42_0019 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D WM42_0871 impB/mucB/samB family protein K14161 imuB; protein ImuB
D WM42_0864 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D WM42_2011 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D WM42_1570 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D WM42_1958 single-strand binding family protein K03111 ssb; single-strand DNA-binding protein
D WM42_2452 recX family protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D WM42_1910 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D WM42_0569 helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D WM42_0349 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_1716 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_1315 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D WM42_0197 NUDIX domain protein K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D WM42_0022 NUDIX domain protein K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D WM42_2531 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D WM42_1904 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D WM42_2055 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D WM42_1906 nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D WM42_2054 nrdF; ribonucleotide reductase subunit R2F K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D WM42_2422 DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024