+E	Replication protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Replication Proteins - Acetoanaerobium sticklandii</h2>
%<!-- w=600, -->
!
A<b>Eukaryotic type</b>
B  DNA Replication Initiation Factors
C    pre-RC (pre-replication complex)
C    CDK (cyclin dependent kinase)
C    DDK (Dbf-4 dependent kinase)
C    GINS complex
C    Other initiation factors
B  DNA Replication Elongation Factors
C    DNA polymerase alpha / primase complex
C    DNA polymerase epsilon complex
C    DNA polymerase delta complex
C    DNA polymerase gamma complex (mitochondrial)
C    RPA (replication protein A)
C    RFC (replication factor C)
C    RNase H
C    Other elongation factors
B  DNA Replication Termination Factors
C    DNA methylation enzymes
D      CLOST_0308 Cytosine-specific methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      CLOST_0310 Cytosine-specific methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      CLOST_0811 Modification methylase Sau3AI (Cytosine-specific methyltransferase Sau3AI) (M.Sau3AI) (fragment)	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      CLOST_1542 C-5 cytosine-specific DNA methylase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
C    Prevention of re-replication factors
C    Telomere proteins
D      Shelterin complex
D      TERB1-TERB2-MAJIN complex
D      CST complex (animals)
D      CST complex (yeast)
D      RIF proteins
D      SIR proteins
C    Telomerase complex (animals)
D      Dyskerin complex
C    Telomerase complex (fungi)
D      Sm core complex
C    ELG1-RFC complex
C    MRN complex
C    Other termination factors
B  DNA Topoisomerases
#
A<b>Prokaryotic type</b>
B  DNA Replication Initiation Factors
C    Initiation factors (bacterial)
D      CLOST_0342 hupB; HU, DNA-binding transcriptional regulator, beta subunit	K03530 hupB; DNA-binding protein HU-beta 
D      CLOST_0001 dnaA; chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator	K02313 dnaA; chromosomal replication initiator protein 
D      CLOST_2564 dnaB; replicative DNA helicase	K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] 
D      CLOST_2559 Chromosomal replication initiator, DnaA	K02315 dnaC; DNA replication protein DnaC 
D      CLOST_1756 dnaG; DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101] 
D      CLOST_1541 ssb; Single-stranded DNA-binding protein 3 (SSB 3) (Helix-destabilizing protein 3)	K03111 ssb; single-strand DNA-binding protein 
D      CLOST_2570 ssb; Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein)	K03111 ssb; single-strand DNA-binding protein 
C    Initiation factors (archaeal)
B  DNA Replication Elongation Factors
C    Elongation factors (bacterial)
D      DNA polymerase III holoenzyme
E        CLOST_1649 dnaE; DNA polymerase III DnaE	K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] 
E        CLOST_1695 polC; DNA polymerase III PolC	K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] 
E        CLOST_0002 DNA polymerase III subunit beta	K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] 
E        CLOST_1805 conserved protein of unknown function	K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] 
E        CLOST_2146 putative DNA polymerase III, delta' subunit	K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] 
E        CLOST_0108 dnaX; DNA polymerase III subunits gamma and tau	K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] 
D      RNase H
E        CLOST_1573 rnhB; Ribonuclease HII (RNase HII)	K03470 rnhB; ribonuclease HII [EC:3.1.26.4] 
D      Other elongation factors
E        CLOST_1407 polA; DNA polymerase I	K02335 polA; DNA polymerase I [EC:2.7.7.7] 
E        CLOST_0579 ligA; DNA ligase, NAD(+)-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
C    Elongation factors (archaeal)
D      B-family DNA polymerases
D      D-family DNA polymerases
D      RNase H
E        CLOST_1573 rnhB; Ribonuclease HII (RNase HII)	K03470 rnhB; ribonuclease HII [EC:3.1.26.4] 
D      RFC (replication factor C)
D      Other elongation factors
B  DNA Replication Termination Factors
C    Terminus site-binding protein
C    DNA methylation enzymes
D      CLOST_1547 Phage modification methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
C    Prevention of re-replication factors
B  DNA Topoisomerases
C    CLOST_0006 gyrA; DNA gyrase (type II topoisomerase), subunit A	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] 
C    CLOST_0005 gyrB; DNA gyrase (subunit B)	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] 
C    CLOST_1498 topA; TopA	K03168 topA; DNA topoisomerase I [EC:5.6.2.1] 
C    CLOST_0824 DNA topoisomerase	K03169 topB; DNA topoisomerase III [EC:5.6.2.1] 
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: July 3, 2025