+E Ubiquitin system KO
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Ubiquitin System - Thermochaetoides thermophila
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C CTHT_0018840 40S ribosomal protein S27a-like protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C CTHT_0057450 ubiquitin-like protein K12158 NEDD8; ubiquitin-like protein Nedd8
C CTHT_0004990 hypothetical protein K08341 GABARAP; GABA(A) receptor-associated protein
C CTHT_0040630 putative autophagy protein K08336 ATG12; ubiquitin-like protein ATG12
C CTHT_0062030 ubiquitin-like protein K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C CTHT_0030680 hypothetical protein K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C CTHT_0025850 hypothetical protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C CTHT_0001750 ubiquitin-activating enzyme-like protein K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C CTHT_0057060 hypothetical protein K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C CTHT_0033830 nedd8-activating enzyme E1 regulatory subunit-like protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CTHT_0055980 URM1 activating enzyme-like protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C CTHT_0052280 putative autophagy protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C CTHT_0034330 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C CTHT_0059150 hypothetical protein K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C CTHT_0016670 putative ubiquitin protein K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C CTHT_0035290 ubiquitin conjugating enzyme-like protein K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C CTHT_0065240 putative ubiquitin carrier protein K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C CTHT_0040610 putative ubiquitin carrier protein K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C CTHT_0066150 ubiquitin conjugating enzyme-like protein K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C CTHT_0046550 hypothetical protein K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C CTHT_0068810 putative ubiquitin carrier protein K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C CTHT_0013270 putative ubiquitin carrier protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C CTHT_0028710 putative ubiquitin carrier protein K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C CTHT_0009500 small conjugating protein ligase-like protein K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C CTHT_0057920 putative ubiquitin protein K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C CTHT_0063140 putative ubiquitin carrier protein K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C CTHT_0051670 putative ubiquitin protein K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C CTHT_0011910 putative autophagy protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C CTHT_0042980 hypothetical protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C CTHT_0043540 ubiquitin-protein ligase-like protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C CTHT_0046110 E3 ubiquitin-protein ligase RSP5-like protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C CTHT_0005350 E3 ubiquitin protein ligase TOM1-like protein K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C CTHT_0002410 ubiquitin-protein ligase-like protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C CTHT_0001560 putative ubiquitin fusion degradation protein K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C CTHT_0036200 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C CTHT_0070810 putative cis-trans protein K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C CTHT_0072540 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D CTHT_0025710 E3 ubiquitin-protein ligase-like protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D CTHT_0040090 hypothetical protein K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D CTHT_0056760 putative fkbp12-associated protein K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D CTHT_0056730 putative peroxin-10 protein K13346 PEX10; peroxin-10
D CTHT_0030320 putative peroxisome protein K13345 PEX12; peroxin-12
D CTHT_0058690 putative peroxisome assembly protein K06664 PEX2; peroxin-2
C RBR proteins
D CTHT_0017500 hypothetical protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D CTHT_0065370 hypothetical protein K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D CTHT_0036830 hypothetical protein K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
D CTHT_0001550 putative ubiquitin fusion degradation protein K09849 TRAF5; TNF receptor-associated factor 5
C TRIM/RBCC proteins
C UBR box proteins
D CTHT_0056400 E3 ubiquitin-protein ligase ubr1-like protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CTHT_0063210 hypothetical protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D CTHT_0041250 hypothetical protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D CTHT_0043390 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D CTHT_0037220 putative finger protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D CTHT_0039180 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CTHT_0046290 hypothetical protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D CTHT_0029990 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D CTHT_0001100 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D CTHT_0002250 putative RNA splicing factor K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D CTHT_0061590 helicase-like protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D CTHT_0031370 helicase-like protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CTHT_0068020 hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CTHT_0000320 hypothetical protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D CTHT_0065750 hypothetical protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D CTHT_0026770 hypothetical protein K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
C CTHT_0038170 putative DNA repair protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C CTHT_0070280 hypothetical protein K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C CTHT_0043940 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C CTHT_0072200 hypothetical protein K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTHT_0039150 ubiquitin-protein ligase-like protein K03347 CUL1; cullin 1
D Adaptor protein
E CTHT_0027110 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E CTHT_0019790 hypothetical protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E CTHT_0021870 hypothetical protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E CTHT_0021800 hypothetical protein K10259 MET30; F-box and WD-40 domain protein MET30
E CTHT_0069810 hypothetical protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CTHT_0064130 hypothetical protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CTHT_0025520 hypothetical protein K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E CTHT_0074140 hypothetical protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E CTHT_0068880 hypothetical protein K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E CTHT_0048790 hypothetical protein K10301 FBXO21; F-box protein 21
E CTHT_0061580 putative F-box protein K15071 RCY1; recyclin-1
C Cul2 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CTHT_0006430 putative elongin-C protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTHT_0072900 putative ubiquitin-protein K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E CTHT_0014260 BTB/POZ domain-containing protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTHT_0025600 ubiquitin ligase activity-like protein K10609 CUL4; cullin 4
D Adoptor protein
E CTHT_0036510 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E CTHT_0047760 putative WD repeat protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E CTHT_0013160 putative WD repeat protein K11801 DCAF11; DDB1- and CUL4-associated factor 11
E CTHT_0005890 hypothetical protein K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CTHT_0061820 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
E CTHT_0049270 WD repeat-containing protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E CTHT_0006430 putative elongin-C protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E CTHT_0027110 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E CTHT_0023610 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E CTHT_0003290 anaphase-promoting complex subunit-like protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E CTHT_0058150 putative cell division control protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E CTHT_0066310 hypothetical protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E CTHT_0020110 anaphase-promoting complex-like protein K03348 APC1; anaphase-promoting complex subunit 1
E CTHT_0022660 anaphase-promoting complex subunit-like protein K03350 APC3; anaphase-promoting complex subunit 3
E CTHT_0026320 anaphase-promoting complex-like protein K03351 APC4; anaphase-promoting complex subunit 4
E CTHT_0029320 anaphase-promoting complex-like protein K03353 APC6; anaphase-promoting complex subunit 6
E CTHT_0028570 hypothetical protein K03355 APC8; anaphase-promoting complex subunit 8
E CTHT_0007590 anaphase promoting complex subunit 10-like protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D CTHT_0009770 hypothetical protein K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D CTHT_0073600 hypothetical protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D CTHT_0051550 hypothetical protein K23334 RANBP9_10; Ran-binding protein 9/10
D CTHT_0013540 hypothetical protein K23336 ARMC8; armadillo repeat-containing protein 8
D CTHT_0025790 hypothetical protein K18624 MAEA; macrophage erythroblast attacher
D CTHT_0034850 hypothetical protein K23335 GID4; glucose-induced degradation protein 4
D CTHT_0039350 hypothetical protein K23338 GID8; glucose-induced degradation protein 8
D CTHT_0061820 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
D CTHT_0006760 hypothetical protein K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D CTHT_0027780 putative TATA binding protein interacting protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D CTHT_0055830 hypothetical protein K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D CTHT_0032880 ubiquitin carboxyl-terminal hydrolase-like protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D CTHT_0048820 ubiquitin thiolesterase-like protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D CTHT_0067960 putative 26S proteasome-associated ubiquitin protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D CTHT_0026420 ubiquitin carboxyl-terminal hydrolase-like protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D CTHT_0047410 ubiquitin carboxyl-terminal hydrolase-like protein K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D CTHT_0061210 ubiquitin carboxyl-terminal hydrolase-like protein K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D CTHT_0063590 ubiquitin carboxyl-terminal hydrolase-like protein K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D CTHT_0011600 ubiquitin carboxyl-terminal hydrolase-like protein K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D CTHT_0048760 ubiquitin carboxyl-terminal hydrolase-like protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D CTHT_0016620 ubiquitin carboxyl-terminal hydrolase-like protein K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D CTHT_0024430 ubiquitin thiolesterase-like protein K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D CTHT_0028890 terminal hydrolase-like protein K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D CTHT_0056860 ubiquitin carboxyl-terminal hydrolase-like protein K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
C OTU
D CTHT_0001060 hypothetical protein K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D CTHT_0051590 OTU domain-containing protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D CTHT_0001620 hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D CTHT_0055580 26S proteasome regulatory subunit rpn11-like protein K03030 PSMD14; 26S proteasome regulatory subunit N11
D CTHT_0018550 hypothetical protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D CTHT_0053320 hypothetical protein K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D CTHT_0028040 hypothetical protein K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
B UBL-specific proteases (ULPs)
C CTHT_0065040 cysteine-type peptidase-like protein K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C CTHT_0056000 nedd8-specific protease-like protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C CTHT_0032880 ubiquitin carboxyl-terminal hydrolase-like protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C COP9 signalosome (CSN) complex
D CTHT_0024380 cop9 signalosome complex subunit 1-like protein K12175 GPS1; COP9 signalosome complex subunit 1
D CTHT_0001200 putative COP9 signalosome protein K12176 COPS2; COP9 signalosome complex subunit 2
D CTHT_0051750 hypothetical protein K12177 COPS3; COP9 signalosome complex subunit 3
D CTHT_0003680 putative COP9 signalosome protein K12178 COPS4; COP9 signalosome complex subunit 4
D CTHT_0037820 complex subunit 6-like protein K12179 COPS6; COP9 signalosome complex subunit 6
D CTHT_0059120 putative COP9 signalosome protein K12180 COPS7; COP9 signalosome complex subunit 7
D CTHT_0056910 cop9 signalosome complex subunit-like protein K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 27, 2024