+D Protein KO
#
Membrane Trafficking - Thermochaetoides thermophila
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
D CTHT_0032480 septin-like protein K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D CTHT_0007310 serine/threonine protein kinase-like protein K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D CTHT_0066170 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D CTHT_0007830 inositol or phosphatidylinositol phosphodiesterase-like protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D CTHT_0038480 phospholipase D-like protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D CTHT_0046000 phospholipase D-like protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D CTHT_0016710 phosphatidylinositol-4-phosphate 5-kinase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D CTHT_0044110 hypothetical protein K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D CTHT_0061910 hypothetical protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D CTHT_0055820 hypothetical protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D CTHT_0064950 putative nucleoside protein K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D CTHT_0041130 hypothetical protein K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D CTHT_0030160 putative calcium ion binding protein K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D CTHT_0032610 hypothetical protein K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D CTHT_0067840 putative calmodulin protein K02183 CALM; calmodulin
D CTHT_0011530 putative GDP-GTP exchange factor K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D CTHT_0033310 5-amino-6-(5-phosphoribosylamino)uracil reductase-like protein K15292 STXBP1; syntaxin-binding protein 1
D CTHT_0016850 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
D CTHT_0068930 phosphatase-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D CTHT_0035870 GTPase-activating protein gyp3-like protein K19953 GRTP1; TBC1 domain family member 6
D CTHT_0007900 GTPase-activating protein gyp2-like protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D CTHT_0008970 hypothetical protein K13342 PEX5; peroxin-5
D CTHT_0014290 putative escort protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D CTHT_0004670 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D CTHT_0057280 hypothetical protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D CTHT_0008780 regulator of V-ATPase-like protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D CTHT_0069960 cell division control protein 42-like protein K04393 CDC42; cell division control protein 42
D CTHT_0013050 GTPase rac-like protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D CTHT_0043330 putative exocyst complex component sec3 protein K19983 EXOC1; exocyst complex component 1
D CTHT_0033650 hypothetical protein K17637 EXOC2; exocyst complex component 2
D CTHT_0001930 putative integral membrane protein K06110 EXOC3; exocyst complex component 3
D CTHT_0061930 putative exocyst complex component sec8 protein K06111 EXOC4; exocyst complex component 4
D CTHT_0059750 putative exocyst complex component sec10 protein K19984 EXOC5; exocyst complex component 5
D CTHT_0022530 putative exocyst complex component sec15 protein K19985 EXOC6; exocyst complex component 6
D CTHT_0034090 putative exocyst complex protein K07195 EXOC7; exocyst complex component 7
D CTHT_0034630 hypothetical protein K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D CTHT_0037380 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D CTHT_0027890 putative tropomyosin protein K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D CTHT_0012620 hypothetical protein K19877 CHS5; chitin biosynthesis protein CHS5
D CTHT_0035890 hypothetical protein K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D CTHT_0064800 hypothetical protein K12481 RBSN; rabenosyn-5
D CTHT_0000520 hypothetical protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D CTHT_0048070 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
D CTHT_0062890 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D CTHT_0067830 putative late golgi protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D CTHT_0011500 hypothetical protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D CTHT_0060490 putative vesicle transport V-snare protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D CTHT_0009630 putative golgi snare protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
C Sec20
D CTHT_0054270 hypothetical protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
D CTHT_0004340 hypothetical protein K08501 STX8; syntaxin 8
D CTHT_0022160 putative phosphoinositide binding protein K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D CTHT_0013500 hypothetical protein K08504 BET1; blocked early in transport 1
D CTHT_0044170 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D CTHT_0060980 hypothetical protein K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D CTHT_0014800 hypothetical protein K08513 VAMP4; vesicle-associated membrane protein 4
D CTHT_0032860 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D CTHT_0026260 synaptobrevin-like protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D CTHT_0028250 hypothetical protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D CTHT_0016850 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D CTHT_0033310 5-amino-6-(5-phosphoribosylamino)uracil reductase-like protein K15292 STXBP1; syntaxin-binding protein 1
D CTHT_0062650 hypothetical protein K19998 SCFD1; sec1 family domain-containing protein 1
D CTHT_0066270 hypothetical protein K26808 TXLN; taxilin
C Palmitoyltransferases
D CTHT_0066160 palmitoyltransferase-like protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D CTHT_0043590 palmitoyltransferase-like protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D CTHT_0022030 palmitoyltransferase-like protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D CTHT_0006660 vesicular-fusion protein sec18-like protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D CTHT_0008760 vesicular-fusion protein sec17-like protein K15296 NAPA; alpha-soluble NSF attachment protein
D CTHT_0073420 hypothetical protein K17919 SNX4; sorting nexin-4
D CTHT_0023020 mRNA capping enzyme alpha subunit-like protein K21996 SNX41_42; sorting nexin-41/42
D CTHT_0017380 putative vacuolar protein sorting-associated protein K15620 GOLPH3; golgi phosphoprotein 3
D CTHT_0027280 putative cell division control protein K13525 VCP; transitional endoplasmic reticulum ATPase
D CTHT_0069140 hypothetical protein K14012 NSFL1C; UBX domain-containing protein 1
D CTHT_0027430 hypothetical protein K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D CTHT_0072960 putative clathrin heavy chain protein K04646 CLTC; clathrin heavy chain
C Dynamin
D CTHT_0059440 hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D CTHT_0005520 AP-2 complex subunit alpha-like protein K11824 AP2A; AP-2 complex subunit alpha
D CTHT_0039490 complex subunit beta-like protein K11825 AP2B1; AP-2 complex subunit beta-1
D CTHT_0050570 AP-1 complex subunit mu-1-like protein K11826 AP2M1; AP-2 complex subunit mu-1
D CTHT_0034270 hypothetical protein K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D CTHT_0036620 putative suppressor of profilin protein K20042 FCHO; F-BAR domain only protein
D CTHT_0042580 hypothetical protein K12471 EPN; epsin
D CTHT_0055380 hypothetical protein K12471 EPN; epsin
D CTHT_0015240 putative calcium ion binding protein K12472 EPS15; epidermal growth factor receptor substrate 15
D CTHT_0060800 putative clathrin binding protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D CTHT_0051240 putative hmp1 protein K12562 AMPH; amphiphysin
D CTHT_0003190 putative actin cytoskeleton-regulatory complex protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D CTHT_0023240 putative actin cytoskeleton-regulatory complex protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D CTHT_0038390 putative actin cytoskeleton-regulatory complex protein K20048 END3; actin cytoskeleton-regulatory complex protein END3
D CTHT_0007430 heat shock protein 70-like protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CTHT_0058460 hypothetical protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D CTHT_0016710 phosphatidylinositol-4-phosphate 5-kinase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D CTHT_0071700 hypothetical protein K20059 LDB19; arrestin-related trafficking adapter 1
D CTHT_0072120 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D CTHT_0043970 hypothetical protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D CTHT_0053540 hypothetical protein K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D CTHT_0068930 phosphatase-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D CTHT_0054150 hypothetical protein K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D CTHT_0024900 hypothetical protein K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D CTHT_0042880 hypothetical protein K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D CTHT_0046110 E3 ubiquitin-protein ligase RSP5-like protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D CTHT_0011900 hypothetical protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D CTHT_0053590 hypothetical protein K08054 CANX; calnexin
D CTHT_0030630 hypothetical protein K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D CTHT_0059440 hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D CTHT_0037100 hypothetical protein K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
D CTHT_0019930 hypothetical protein K07192 FLOT; flotillin
C GRAF1-dependent endocytosis
D CTHT_0069960 cell division control protein 42-like protein K04393 CDC42; cell division control protein 42
D CTHT_0058060 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D CTHT_0041850 putative ADP-ribosylation factor K07941 ARF6; ADP-ribosylation factor 6
D CTHT_0013050 GTPase rac-like protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D CTHT_0013650 GTP-binding protein rho1-like protein K04513 RHOA; Ras homolog gene family, member A
D CTHT_0059440 hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D CTHT_0058670 hypothetical protein K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D CTHT_0039070 ras-like protein K07827 KRAS; GTPase KRas
D CTHT_0051640 ras-like protein K07827 KRAS; GTPase KRas
D CTHT_0013050 GTPase rac-like protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D CTHT_0069960 cell division control protein 42-like protein K04393 CDC42; cell division control protein 42
C Kinases
D CTHT_0013240 phosphatidylinositol 3-kinase-like protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CTHT_0058410 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D CTHT_0044110 hypothetical protein K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D CTHT_0066170 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D CTHT_0007830 inositol or phosphatidylinositol phosphodiesterase-like protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D CTHT_0068290 putative vacuolar protein sorting-associated protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D CTHT_0051240 putative hmp1 protein K12562 AMPH; amphiphysin
D CTHT_0069000 hypothetical protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D CTHT_0052420 hypothetical protein K20121 FNBP1; formin-binding protein 1
D CTHT_0036620 putative suppressor of profilin protein K20042 FCHO; F-BAR domain only protein
D CTHT_0014700 putative GTPase-activating protein K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D CTHT_0073810 hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
D CTHT_0070620 vacuolar protein sorting-associated protein 21-like protein K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D CTHT_0035070 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D CTHT_0064800 hypothetical protein K12481 RBSN; rabenosyn-5
D CTHT_0068930 phosphatase-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D CTHT_0013240 phosphatidylinositol 3-kinase-like protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CTHT_0034670 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D CTHT_0023980 putative vacuolar protein sorting-associated protein K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D CTHT_0058060 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D CTHT_0041850 putative ADP-ribosylation factor K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D CTHT_0044160 ARF GTPase activator-like protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D CTHT_0010250 phosphatidylinositol-4- kinase-like protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D CTHT_0008180 hypothetical protein K21842 EFR3; protein EFR3
D CTHT_0025140 hypothetical protein K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D CTHT_0073810 hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
D CTHT_0070620 vacuolar protein sorting-associated protein 21-like protein K07889 RAB5C; Ras-related protein Rab-5C
D CTHT_0065990 rab small monomeric GTPase-like protein K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D CTHT_0035730 hypothetical protein K18468 VPS35; vacuolar protein sorting-associated protein 35
D CTHT_0002370 putative vacuolar protein sorting-associated protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D CTHT_0009750 vacuolar protein sorting-associated protein 26-like protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D CTHT_0005040 hypothetical protein K16536 HOOK3; protein HOOK3
C Rab associated proteins
D CTHT_0029990 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D CTHT_0001100 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D CTHT_0013240 phosphatidylinositol 3-kinase-like protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CTHT_0069850 hypothetical protein K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D CTHT_0061650 GTPase-activating protein gyp7-like protein K20168 TBC1D15; TBC1 domain family member 15
D CTHT_0014290 putative escort protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D CTHT_0004670 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D CTHT_0057280 hypothetical protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D CTHT_0001680 hypothetical protein K20176 SGSM3; small G protein signaling modulator 3
D CTHT_0017380 putative vacuolar protein sorting-associated protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D CTHT_0048380 N-terminal acetyltransferase C complex catalytic subunit mak3-like protein K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D CTHT_0007230 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D CTHT_0044300 hypothetical protein K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D CTHT_0042300 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D CTHT_0045720 hypothetical protein K12183 TSG101; ESCRT-I complex subunit TSG101
D CTHT_0059010 hypothetical protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D CTHT_0071320 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D CTHT_0043710 putative ESCRT-II complex protein K12189 VPS25; ESCRT-II complex subunit VPS25
D CTHT_0036750 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D CTHT_0011070 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D CTHT_0026570 putative vacuolar-protein sorting-associated protein K12191 CHMP2A; charged multivesicular body protein 2A
D CTHT_0005580 putative vps protein K12193 VPS24; charged multivesicular body protein 3
D CTHT_0052810 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D CTHT_0019800 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D CTHT_0002570 vacuolar protein sorting-associated protein 20-like protein K12195 CHMP6; charged multivesicular body protein 6
D CTHT_0039190 hypothetical protein K15053 CHMP7; charged multivesicular body protein 7
D CTHT_0018520 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D CTHT_0055590 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D CTHT_0020270 hypothetical protein K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D CTHT_0067920 tgf beta receptor associated protein 1-like protein K20177 VPS3; vacuolar protein sorting-associated protein 3
D CTHT_0055030 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D CTHT_0015500 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D CTHT_0026760 putative vacuolar protein sorting-associated protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D CTHT_0023300 putative vacuolar protein sorting-associated protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CTHT_0057760 small conjugating protein ligase-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D CTHT_0015500 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D CTHT_0026760 putative vacuolar protein sorting-associated protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D CTHT_0023300 putative vacuolar protein sorting-associated protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D CTHT_0057760 small conjugating protein ligase-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D CTHT_0004950 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D CTHT_0020120 hypothetical protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D CTHT_0008780 regulator of V-ATPase-like protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D CTHT_0008780 regulator of V-ATPase-like protein K24155 DMXL; rabconnectin-3a
D CTHT_0027110 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D CTHT_0066690 AP-3 complex subunit delta-like protein K12396 AP3D; AP-3 complex subunit delta
D CTHT_0036950 AP-3 complex subunit beta-like protein K12397 AP3B; AP-3 complex subunit beta
D CTHT_0045100 complex subunit mu-like protein K12398 AP3M; AP-3 complex subunit mu
D CTHT_0015420 AP-3 complex subunit sigma-like protein K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D CTHT_0006620 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D CTHT_0067370 hypothetical protein K20195 MON1; vacuolar fusion protein MON1
D CTHT_0018550 hypothetical protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D CTHT_0061810 putative sorting protein K23481 VPS1; vacuolar protein sorting-associated protein 1
D CTHT_0008150 hypothetical protein K24781 BPH1; beige protein homolog 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D CTHT_0004810 putative GTP-binding protein K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D CTHT_0064800 hypothetical protein K12481 RBSN; rabenosyn-5
D CTHT_0073420 hypothetical protein K17919 SNX4; sorting nexin-4
D CTHT_0010980 putative motor protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D CTHT_0072660 putative WD repeat protein K20241 WDR44; WD repeat-containing protein 44
D CTHT_0041110 hypothetical protein K14004 SEC13; protein transport protein SEC13
D CTHT_0022530 putative exocyst complex component sec15 protein K19985 EXOC6; exocyst complex component 6
D CTHT_0017380 putative vacuolar protein sorting-associated protein K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D CTHT_0068930 phosphatase-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D CTHT_0035070 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D CTHT_0009770 hypothetical protein K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D CTHT_0016930 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D CTHT_0029810 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D CTHT_0058820 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D CTHT_0053450 putative F-actin capping protein K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D CTHT_0002370 putative vacuolar protein sorting-associated protein K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D CTHT_0039390 putative GTP-binding protein K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D CTHT_0017380 putative vacuolar protein sorting-associated protein K15620 GOLPH3; golgi phosphoprotein 3
D CTHT_0007900 GTPase-activating protein gyp2-like protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D CTHT_0008890 hypothetical protein K20286 TMF1; TATA element modulatory factor
D CTHT_0012680 hypothetical protein K10419 DYNLRB; dynein light chain roadblock-type
D CTHT_0006840 hypothetical protein K04648 DCTN1; dynactin 1
D CTHT_0068930 phosphatase-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D CTHT_0020450 putative vacuolar protein sorting-associated protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D CTHT_0058060 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D CTHT_0027120 putative ADP-ribosylation factor K07942 ARL1; ADP-ribosylation factor-like protein 1
D CTHT_0027500 putative ADP-ribosylation factor K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D CTHT_0038820 ARF GTPase activator-like protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D CTHT_0044160 ARF GTPase activator-like protein K12486 SMAP; stromal membrane-associated protein
D CTHT_0054320 putative GTPase activating protein K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D CTHT_0032010 hypothetical protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D CTHT_0033970 putative ARF guanine-nucleotide exchange factor K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D CTHT_0025570 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D CTHT_0024930 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D CTHT_0016260 putative oligomeric golgi complex protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D CTHT_0056620 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D CTHT_0048330 hypothetical protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D CTHT_0003010 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D CTHT_0016930 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D CTHT_0029810 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D CTHT_0058820 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D CTHT_0028560 vacuolar protein sorting-associated protein 54-like protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D CTHT_0023180 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D CTHT_0022640 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CTHT_0045180 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CTHT_0047240 hypothetical protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D CTHT_0003220 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D CTHT_0069300 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D CTHT_0070270 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D CTHT_0039200 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D CTHT_0028180 hypercellular protein hypA-like protein K20306 TRAPPC9; trafficking protein particle complex subunit 9
D CTHT_0000130 putative rab guanyl-nucleotide exchange factor K20307 TRAPPC10; trafficking protein particle complex subunit 10
D CTHT_0042850 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D CTHT_0035990 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
B Others
C AP-1 complex
D CTHT_0067850 AP-1 complex subunit gamma-1-like protein K12391 AP1G1; AP-1 complex subunit gamma-1
D CTHT_0019150 AP-1 complex subunit beta-1-like protein K12392 AP1B1; AP-1 complex subunit beta-1
D CTHT_0050630 AP-1 complex subunit mu-1-like protein K12393 AP1M; AP-1 complex subunit mu
D CTHT_0050990 AP-1 complex subunit-like protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D CTHT_0066690 AP-3 complex subunit delta-like protein K12396 AP3D; AP-3 complex subunit delta
D CTHT_0036950 AP-3 complex subunit beta-like protein K12397 AP3B; AP-3 complex subunit beta
D CTHT_0045100 complex subunit mu-like protein K12398 AP3M; AP-3 complex subunit mu
D CTHT_0015420 AP-3 complex subunit sigma-like protein K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D CTHT_0017470 putative ADP-ribosylation factor-binding protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D CTHT_0027080 hypothetical protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D CTHT_0038480 phospholipase D-like protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D CTHT_0046000 phospholipase D-like protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D CTHT_0010250 phosphatidylinositol-4- kinase-like protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D CTHT_0016710 phosphatidylinositol-4-phosphate 5-kinase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D CTHT_0058410 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D CTHT_0016690 putative integral membrane protein K20318 SYS1; protein SYS1
D CTHT_0012080 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D CTHT_0016740 hypothetical protein K23542 TMEM199; TMEM199 family protein
D CTHT_0034250 hypothetical protein K23544 SERINC1; serine incorporator 1
D CTHT_0011560 hypothetical protein K17918 SNX3_12; sorting nexin-3/12
D CTHT_0072190 hypothetical protein K17922 SNX8; sorting nexin-8
D CTHT_0041720 hypothetical protein K26678 MON2; protein MON2
D CTHT_0067380 hypothetical protein K26680 DOP1; protein dopey
D CTHT_0034500 golgi apparatus membrane protein tvp15-like protein K26750 TVP15; golgi apparatus membrane protein TVP15
D CTHT_0042780 hypothetical protein K26751 TVP18; golgi apparatus membrane protein TVP18
D CTHT_0049940 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D CTHT_0061810 putative sorting protein K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D CTHT_0041110 hypothetical protein K14004 SEC13; protein transport protein SEC13
D CTHT_0002660 hypothetical protein K14005 SEC31; protein transport protein SEC31
D CTHT_0066370 hypothetical protein K14006 SEC23; protein transport protein SEC23
D CTHT_0017030 putative ER to golgi transport protein K14007 SEC24; protein transport protein SEC24
D CTHT_0048450 hypothetical protein K14007 SEC24; protein transport protein SEC24
D CTHT_0067660 putative COPII coat protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D CTHT_0023180 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D CTHT_0022640 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CTHT_0045180 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D CTHT_0047240 hypothetical protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D CTHT_0003220 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D CTHT_0069300 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D CTHT_0070270 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D CTHT_0045130 hypothetical protein K20346 TMED4_9_11; p24 family protein alpha
D CTHT_0058050 hypothetical protein K20347 TMED2; p24 family protein beta-1
D CTHT_0051870 hypothetical protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D CTHT_0067360 hypothetical protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D CTHT_0055600 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D CTHT_0065740 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D CTHT_0008620 hypothetical protein K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D CTHT_0073050 putative ER to golgi transport protein K20359 RABAC1; PRA1 family protein 1
D CTHT_0029820 rab GTPase activator-like protein K20372 TBC1D20; TBC1 domain family member 20
D CTHT_0062480 putative GTPase activating protein K20360 TBC1D22; TBC1 domain family member 2
D CTHT_0014580 putative ER-To-golgi transport protein K20362 YIF1; protein transport protein YIF1
D CTHT_0008820 intracellular protein transport-like protein K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D CTHT_0024750 hypothetical protein K10080 LMAN1; lectin, mannose-binding 1
D CTHT_0023750 hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D CTHT_0050430 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D CTHT_0016550 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D CTHT_0068950 alpha-mannosidase-like protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D CTHT_0060640 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D CTHT_0054060 mannosyl-oligosaccharide 1,2-alpha-mannosidase-like protein K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D CTHT_0063020 hypothetical protein K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D CTHT_0054620 hypothetical protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D CTHT_0017820 hypothetical protein K20368 CNIH; protein cornichon
D CTHT_0057550 hypothetical protein K20369 ERV29; ER-derived vesicles protein
D CTHT_0044200 hypothetical protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D CTHT_0049000 putative coatomer complex protein K05236 COPA; coatomer subunit alpha
D CTHT_0034860 coatomer subunit beta-like protein K17301 COPB1; coatomer subunit beta
D CTHT_0037490 hypothetical protein K17302 COPB2; coatomer subunit beta'
D CTHT_0012100 coatomer subunit gamma-like protein K17267 COPG; coatomer subunit gamma
D CTHT_0026330 coatomer subunit delta-like protein K20471 COPD; coatomer subunit delta
D CTHT_0052450 coatomer subunit epsilon-like protein K17268 COPE; coatomer subunit epsilon
D CTHT_0057140 hypothetical protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D CTHT_0016280 hypothetical protein K20474 RINT1; RAD50-interacting protein 1
D CTHT_0066190 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D CTHT_0065010 hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D CTHT_0002670 hypothetical protein K22386 GET2; GET complex subunit GET2
D CTHT_0061710 arsenite translocating ATPase-like protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D CTHT_0028730 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
D CTHT_0006060 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
D CTHT_0039390 putative GTP-binding protein K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D CTHT_0010000 enzyme regulator-like protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D CTHT_0013740 hypothetical protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D CTHT_0013770 hypothetical protein K10949 KDELR; ER lumen protein retaining receptor
D CTHT_0064800 hypothetical protein K12481 RBSN; rabenosyn-5
D CTHT_0062480 putative GTPase activating protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D CTHT_0014900 putative oxysterol-binding protein K20456 OSBP; oxysterol-binding protein 1
D CTHT_0017390 putative oxysterol binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D CTHT_0010330 putative oxysterol binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D CTHT_0020700 putative oxysterol binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D CTHT_0029780 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D CTHT_0044610 hypothetical protein K20363 YIPF5_7; protein YIPF5/7
D CTHT_0029930 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D CTHT_0014680 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D CTHT_0066700 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D CTHT_0009180 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D CTHT_0039480 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D CTHT_0008590 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
C SEC61 complex
D CTHT_0069570 hypothetical protein K10956 SEC61A; protein transport protein SEC61 subunit alpha
D CTHT_0056870 hypothetical protein K09481 SEC61B; protein transport protein SEC61 subunit beta
D CTHT_0061700 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D CTHT_0024800 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D CTHT_0034210 hypothetical protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D CTHT_0054610 hypothetical protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D CTHT_0057430 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D CTHT_0074670 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D CTHT_0062650 hypothetical protein K19998 SCFD1; sec1 family domain-containing protein 1
D CTHT_0035480 hypothetical protein K20724 TMEM33; transmembrane protein 33
D CTHT_0017380 putative vacuolar protein sorting-associated protein K15620 GOLPH3; golgi phosphoprotein 3
D CTHT_0071500 hypothetical protein K26681 INSIG; insulin-induced protein
D CTHT_0032690 putative golgi transport protein K26683 GOLT1; vesicle transport protein GOT1
D CTHT_0007480 hypothetical protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D CTHT_0042310 putative autophagy protein K08331 ATG13; autophagy-related protein 13
D CTHT_0023220 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D CTHT_0070950 serine/threonine protein kinase-like protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D CTHT_0042310 putative autophagy protein K08331 ATG13; autophagy-related protein 13
D CTHT_0021470 putative autophagy protein K08329 ATG17; autophagy-related protein 17
C PI3K complex
D CTHT_0013240 phosphatidylinositol 3-kinase-like protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D CTHT_0034670 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D CTHT_0060470 hypothetical protein K08334 BECN; beclin
C ATG9 transmembrane protein
D CTHT_0048320 putative mitochondrial carrier protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D CTHT_0002060 putative autophagy protein K17908 WIPI1_2; autophagy-related protein 18
D CTHT_0063370 hypothetical protein K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D CTHT_0040630 putative autophagy protein K08336 ATG12; ubiquitin-like protein ATG12
D CTHT_0052280 putative autophagy protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D CTHT_0050860 putative autophagy protein K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D CTHT_0004990 hypothetical protein K08341 GABARAP; GABA(A) receptor-associated protein
D CTHT_0048230 cysteine protease-like protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D CTHT_0052280 putative autophagy protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D CTHT_0011910 putative autophagy protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D CTHT_0065300 aminopeptidase-like protein K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D CTHT_0067100 alpha-mannosidase-like protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D CTHT_0070450 aspartyl aminopeptidase-like protein K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D CTHT_0010290 hypothetical protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D CTHT_0023020 mRNA capping enzyme alpha subunit-like protein K21996 SNX41_42; sorting nexin-41/42
D CTHT_0073420 hypothetical protein K17919 SNX4; sorting nexin-4
D CTHT_0070750 putative lysis of subvacuolar cytoplasm to vacuole targeted bodies protein K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D CTHT_0007140 hypothetical protein K21141 ATG27; autophagy-related protein 27
D CTHT_0028960 hypothetical protein K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D CTHT_0010290 hypothetical protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D CTHT_0026580 transmembrane GTPase-like protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D CTHT_0062850 zinc-binding domain-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D CTHT_0014980 hypothetical protein K00844 HK; hexokinase [EC:2.7.1.1]
D CTHT_0041180 hexokinase-like protein K00844 HK; hexokinase [EC:2.7.1.1]
D CTHT_0057190 hexokinase-like protein K00844 HK; hexokinase [EC:2.7.1.1]
D CTHT_0054400 hypothetical protein K22255 ATPIF1; ATPase inhibitor, mitochondrial
D CTHT_0061990 import receptor subunit-like protein K17771 TOM7; mitochondrial import receptor subunit TOM7
D CTHT_0031200 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D CTHT_0023210 peroxisomal biogenesis factor 3-like protein K13336 PEX3; peroxin-3
D CTHT_0043690 putative peroxisomal membrane anchor protein K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D CTHT_0062850 zinc-binding domain-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
D CTHT_0057230 hypothetical protein K13338 PEX1; peroxin-1
D CTHT_0057860 putative peroxisome biosynthesis protein K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D CTHT_0062850 zinc-binding domain-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D CTHT_0027280 putative cell division control protein K13525 VCP; transitional endoplasmic reticulum ATPase
D CTHT_0004840 hypothetical protein K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D CTHT_0036200 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
D CTHT_0062850 zinc-binding domain-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D CTHT_0031520 putative aspartate protein K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D CTHT_0004880 glyceraldehyde-3-phosphate dehydrogenase-like protein K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CTHT_0017880 pyruvate kinase-like protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CTHT_0058630 ubiquitin-like protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D CTHT_0007430 heat shock protein 70-like protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CTHT_0058460 hypothetical protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CTHT_0068330 heat shock protein hsp90-like protein K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D CTHT_0012210 putative elongation factor K03231 EEF1A; elongation factor 1-alpha
D CTHT_0026440 serine-type carboxypeptidase-like protein K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D CTHT_0028960 hypothetical protein K08332 VAC8; vacuolar protein 8
C Midbophagy
D CTHT_0062850 zinc-binding domain-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D CTHT_0026580 transmembrane GTPase-like protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D CTHT_0046380 phosphatidylinositol 3-kinase-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D CTHT_0062750 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D CTHT_0014610 hypothetical protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D CTHT_0046380 phosphatidylinositol 3-kinase-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D CTHT_0062750 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D CTHT_0024460 hypothetical protein K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D CTHT_0071360 hmp-phosphate kinase (HMP-P kinase)-like protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
D CTHT_0018610 hypothetical protein K25576 AVO2; target of rapamycin complex 2 subunit AVO2
C SEACIT/GATOR1 complex
D CTHT_0033540 putative vacuolar membrane-associated protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D CTHT_0059100 nitrogen permease regulator-like protein K20405 NPRL2; nitrogen permease regulator 2
D CTHT_0009910 hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D CTHT_0074280 hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D CTHT_0013280 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D CTHT_0025440 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D CTHT_0030710 hypothetical protein K14299 SEH1; nucleoporin SEH1
D CTHT_0041110 hypothetical protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D CTHT_0032610 hypothetical protein K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D CTHT_0034640 serine/threonine-protein phosphatase-like protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D CTHT_0032550 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D CTHT_0074310 putative UV radiation resistance protein K21249 UVRAG; UV radiation resistance-associated gene protein
D CTHT_0057390 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family
D CTHT_0047470 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D CTHT_0061430 putative amino acid transporter protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D CTHT_0011010 hypothetical protein K22991 WDR45; WD repeat-containing protein 45
D CTHT_0073780 hypothetical protein K27411 PHAF1; phagosome assembly factor 1
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D CTHT_0058680 putative FAD binding protein K08008 NOX1; NADPH oxidase 1
D CTHT_0016660 hypothetical protein K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
C Nox associated proteins
D CTHT_0013050 GTPase rac-like protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D CTHT_0058670 hypothetical protein K10356 MYO1; myosin I
D CTHT_0028070 putative myosin MYO2 protein K10357 MYO5; myosin V
C Arp2/3 complex
D CTHT_0054040 actin-related protein 2/3 complex subunit-like protein K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D CTHT_0003440 arp2/3 complex 34 kda subunit-like protein K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D CTHT_0020780 hypothetical protein K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D CTHT_0011590 ARP2/3 complex 20 kDa subunit-like protein K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D CTHT_0005540 putative 3 complex protein K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D CTHT_0041870 hypothetical protein K17260 ACTR2; actin-related protein 2
D CTHT_0004610 hypothetical protein K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D CTHT_0012580 putative wiskott-aldrich syndrome protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D CTHT_0059400 putative actin binding protein K20520 DBNL; drebrin-like protein
D CTHT_0023240 putative actin cytoskeleton-regulatory complex protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D CTHT_0051240 putative hmp1 protein K12562 AMPH; amphiphysin
D CTHT_0003190 putative actin cytoskeleton-regulatory complex protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D CTHT_0037770 putative myosin I binding protein K20521 BBC1; myosin tail region-interacting protein MTI1
D CTHT_0008030 hypothetical protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D CTHT_0044180 putative LAS seventeen-binding protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D CTHT_0044250 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D CTHT_0029460 phosphatidylinositol 4-kinase-like protein K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D CTHT_0032700 hypothetical protein K05759 PFN; profilin
D CTHT_0006070 hypothetical protein K05765 CFL; cofilin
D CTHT_0034130 putative adenylyl cyclase-associated protein K17261 CAP1_2; adenylyl cyclase-associated protein
D CTHT_0034320 kinesin-like protein K10396 KIF5; kinesin family member 5
D CTHT_0023450 hypothetical protein K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D CTHT_0014700 putative GTPase-activating protein K20643 RGD1; Rho GTPase-activating protein RGD1
D CTHT_0073150 GTPase-activating protein (GAP)-like protein K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D CTHT_0053690 hypothetical protein K20705 DNMBP; dynamin-binding protein
D CTHT_0015580 hypothetical protein K05727 DOCK3; dedicator of cytokinesis protein 3
D CTHT_0044990 hypothetical protein K27817 RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: September 2, 2024