+E Ubiquitin system KO
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Ubiquitin System - Candida tropicalis
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C CTRG_05622 ubiquitin K08770 UBC; ubiquitin C
C CTRG_00044 60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C CTRG_03742 ubiquitin K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C CTRG_00453 conserved hypothetical protein K12158 NEDD8; ubiquitin-like protein Nedd8
C CTRG_03667 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
C CTRG_04125 conserved hypothetical protein K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C CTRG_05715 ubiquitin-activating enzyme E1 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C CTRG_05902 hypothetical protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C CTRG_03998 conserved hypothetical protein K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C CTRG_02993 hypothetical protein K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C CTRG_02677 conserved hypothetical protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CTRG_04079 hypothetical protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C CTRG_00668 conserved hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C CTRG_05196 ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C CTRG_05864 ubiquitin-conjugating enzyme E2 4 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C CTRG_05912 ubiquitin-conjugating enzyme E2-18 kDa K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C CTRG_04589 ubiquitin-conjugating enzyme E2-21 kDa 2 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C CTRG_02458 ubiquitin-conjugating enzyme E2 6 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C CTRG_02759 ubiquitin-conjugating enzyme E2-24 kDa K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C CTRG_05270 ubiquitin-conjugating enzyme E2 13 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C CTRG_05171 hypothetical protein K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C CTRG_01929 hypothetical protein K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C CTRG_06148 hypothetical protein K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C CTRG_03100 ubiquitin-conjugating enzyme E2-18 kDa K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C CTRG_06192 NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C CTRG_04389 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C CTRG_00080 conserved hypothetical protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C CTRG_01498 predicted protein K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C CTRG_00964 hypothetical protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C CTRG_01844 E3 ubiquitin--protein ligase RSP5 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C CTRG_01307 hypothetical protein K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C CTRG_02307 hypothetical protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C CTRG_02341 hypothetical protein K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C CTRG_05101 predicted protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C CTRG_03893 predicted protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C CTRG_05612 conserved hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D CTRG_05243 conserved hypothetical protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D CTRG_04997 conserved hypothetical protein K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D CTRG_00904 conserved hypothetical protein K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D CTRG_00008 hypothetical protein K13346 PEX10; peroxin-10
D CTRG_01296 hypothetical protein K13345 PEX12; peroxin-12
D CTRG_01657 conserved hypothetical protein K06664 PEX2; peroxin-2
C RBR proteins
D CTRG_03693 hypothetical protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D CTRG_02498 hypothetical protein K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D CTRG_00339 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CTRG_00340 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CTRG_00402 conserved hypothetical protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D CTRG_01400 conserved hypothetical protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D CTRG_00758 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D CTRG_00005 conserved hypothetical protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D CTRG_02864 predicted protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CTRG_00091 predicted protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D CTRG_05433 predicted protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D CTRG_01745 predicted protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D CTRG_00611 conserved hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CTRG_02828 hypothetical protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D CTRG_05337 hypothetical protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D CTRG_05776 predicted protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D CTRG_03016 conserved hypothetical protein K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
B UBL E3 ligases
C CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C CTRG_04453 predicted protein K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C CTRG_02242 predicted protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C CTRG_01520 predicted protein K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C CTRG_05684 predicted protein K17822 DCUN1D1_2; DCN1-like protein 1/2
C CTRG_05683 predicted protein K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTRG_02143 conserved hypothetical protein K03347 CUL1; cullin 1
D Adaptor protein
E CTRG_04163 suppressor of kinetochore protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E CTRG_04413 protein MET30 K10259 MET30; F-box and WD-40 domain protein MET30
E CTRG_00845 cell division control protein 4 K03361 CDC4; F-box and WD-40 domain protein CDC4
E CTRG_06157 predicted protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E CTRG_01004 conserved hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E CTRG_06022 hypothetical protein K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E CTRG_06183 conserved hypothetical protein K15068 DIA2; protein DIA2
E CTRG_00193 conserved hypothetical protein K10295 FBXO9; F-box protein 9
E CTRG_05296 hypothetical protein K15071 RCY1; recyclin-1
E CTRG_05417 conserved hypothetical protein K15072 SAF1; SCF-associated factor 1
E CTRG_04497 hypothetical protein K15073 UFO1; ubiquitin ligase complex F-box protein UFO1
C Cul2 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CTRG_04707 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTRG_01046 conserved hypothetical protein K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E CTRG_04881 conserved hypothetical protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CTRG_04267 conserved hypothetical protein K10609 CUL4; cullin 4
D Adoptor protein
D Target recognizing subunit (DCAF)
E CTRG_02555 conserved hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E CTRG_03179 conserved hypothetical protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E CTRG_06223 protein SOF1 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CTRG_02124 protein SOF1 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CTRG_06202 protein SOF1 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CTRG_05207 conserved hypothetical protein K22382 WDR26; WD repeat-containing protein 26
E CTRG_04866 conserved hypothetical protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E CTRG_04707 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E CTRG_04163 suppressor of kinetochore protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
E CTRG_01035 predicted protein K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
C Cul9 complex
D Ring finger protein
E CTRG_02424 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E CTRG_05784 anaphase promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E CTRG_05682 hypothetical protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E CTRG_02979 hypothetical protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E CTRG_01113 hypothetical protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E CTRG_02348 hypothetical protein K12782 AMA1; meiosis-specific APC/C activator protein AMA1
D Other subunits
E CTRG_04367 hypothetical protein K03348 APC1; anaphase-promoting complex subunit 1
E CTRG_00962 hypothetical protein K03350 APC3; anaphase-promoting complex subunit 3
E CTRG_05228 conserved hypothetical protein K03351 APC4; anaphase-promoting complex subunit 4
E CTRG_04056 hypothetical protein K03352 APC5; anaphase-promoting complex subunit 5
E CTRG_03877 conserved hypothetical protein K03353 APC6; anaphase-promoting complex subunit 6
E CTRG_03039 conserved hypothetical protein K03355 APC8; anaphase-promoting complex subunit 8
E CTRG_03984 hypothetical protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D CTRG_00891 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D CTRG_04706 conserved hypothetical protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D CTRG_02276 conserved hypothetical protein K18624 MAEA; macrophage erythroblast attacher
D CTRG_05707 conserved hypothetical protein K23335 GID4; glucose-induced degradation protein 4
D CTRG_00436 predicted protein K23338 GID8; glucose-induced degradation protein 8
D CTRG_05207 conserved hypothetical protein K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
D CTRG_01404 predicted protein K22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]
D CTRG_06176 hypothetical protein K22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
C Multi subunit type E3 associated proteins
D CTRG_05593 conserved hypothetical protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D CTRG_04161 conserved hypothetical protein K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D CTRG_04248 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D CTRG_06033 conserved hypothetical protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D CTRG_04237 hypothetical protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D CTRG_01426 hypothetical protein K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D CTRG_02092 conserved hypothetical protein K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D CTRG_03675 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D CTRG_03025 hypothetical protein K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D CTRG_04315 hypothetical protein K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D CTRG_02089 conserved hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D CTRG_00656 hypothetical protein K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D CTRG_02447 predicted protein K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D CTRG_03923 hypothetical protein K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.4.19.12]
D CTRG_01163 hypothetical protein K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D CTRG_00472 hypothetical protein K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D CTRG_04611 conserved hypothetical protein K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D CTRG_05364 conserved hypothetical protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D CTRG_01859 conserved hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D CTRG_03719 26S proteasome regulatory subunit RPN11 K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C CTRG_00755 conserved hypothetical protein K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C CTRG_00737 conserved hypothetical protein K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C CTRG_06173 predicted protein K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C CTRG_02468 conserved hypothetical protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C CTRG_04248 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C CTRG_06151 conserved hypothetical protein K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D CTRG_02073 predicted protein K12176 COPS2; COP9 signalosome complex subunit 2
D CTRG_00474 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D CTRG_06021 conserved hypothetical protein K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024