+F Repair protein KO
#
DNA Repair and Recombination Proteins - Cupriavidus necator NH9
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BJN34_22770 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_35050 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_03540 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_15615 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BJN34_17795 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BJN34_02350 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BJN34_06055 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E BJN34_27985 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BJN34_17480 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BJN34_0120 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BJN34_16295 aminotransferase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BJN34_22770 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_35050 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_03540 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BJN34_27135 bifunctional transcriptional activator/DNA repair enzyme protein Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D BJN34_15615 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D BJN34_34185 alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E BJN34_17795 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BJN34_10755 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E BJN34_06410 Fe-S cluster assembly protein HesB K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E BJN34_35055 DNA-3-methyladenine glycosylase 2 family protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E BJN34_02350 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BJN34_19000 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E BJN34_02340 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E BJN34_06055 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BJN34_01025 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E BJN34_06975 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E BJN34_06175 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E BJN34_10515 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BJN34_14765 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BJN34_02445 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BJN34_29685 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BJN34_06080 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E BJN34_13665 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E BJN34_01815 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_14810 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_35910 DNA/RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_14765 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BJN34_10515 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BJN34_18715 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BJN34_18710 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BJN34_18520 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F BJN34_05090 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BJN34_07370 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BJN34_06360 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E BJN34_16400 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E BJN34_03645 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E BJN34_14730 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E BJN34_04805 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BJN34_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BJN34_15980 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E BJN34_16735 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BJN34_07855 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BJN34_25040 ethanolamine utilization protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BJN34_13040 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BJN34_13225 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BJN34_12190 DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E BJN34_10515 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BJN34_01815 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_14810 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_35910 DNA/RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BJN34_02455 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BJN34_37520 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BJN34_36910 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BJN34_22570 hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E BJN34_0150 hypothetical protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BJN34_03300 recombinase RecA K03553 recA; recombination protein RecA
E BJN34_03070 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BJN34_03065 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BJN34_03080 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E BJN34_19385 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E BJN34_11620 primosomal replication protein N K02686 priB; primosomal replication protein N
E BJN34_21005 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E BJN34_36690 nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BJN34_21000 exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E BJN34_36700 metallophosphatase family protein K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E BJN34_03300 recombinase RecA K03553 recA; recombination protein RecA
E BJN34_10735 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E BJN34_16600 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BJN34_36660 transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BJN34_06175 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E BJN34_13695 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E BJN34_12180 recombination protein RecR K06187 recR; recombination protein RecR
E BJN34_05970 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E BJN34_16990 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E BJN34_03070 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BJN34_03065 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BJN34_03080 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E BJN34_12205 ATP-dependent exonuclease K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E BJN34_12210 recombinase RecB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E BJN34_21005 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E BJN34_36690 nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BJN34_21000 exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E BJN34_36700 metallophosphatase family protein K03547 sbcD; DNA repair protein SbcD/Mre11
E BJN34_04870 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E BJN34_34085 Ku protein K10979 ku; DNA end-binding protein Ku
E BJN34_36620 Ku protein K10979 ku; DNA end-binding protein Ku
E BJN34_34075 ligD; ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E BJN34_36625 ligD; ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BJN34_04450 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BJN34_00015 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F BJN34_27800 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F BJN34_19650 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BJN34_06175 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F BJN34_13695 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F BJN34_12180 recombination protein RecR K06187 recR; recombination protein RecR
F BJN34_10515 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F BJN34_03090 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F BJN34_06865 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F BJN34_04500 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F BJN34_18705 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BJN34_21270 DUF559 domain-containing protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BJN34_21280 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BJN34_02445 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BJN34_29685 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BJN34_06080 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F BJN34_0035 hypothetical protein K03746 hns; DNA-binding protein H-NS
F BJN34_01945 histidine biosynthesis protein K03746 hns; DNA-binding protein H-NS
F BJN34_24365 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_29915 histone-like nucleoid-structuring protein K03746 hns; DNA-binding protein H-NS
F BJN34_21295 hypothetical protein K03746 hns; DNA-binding protein H-NS
F BJN34_21315 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_21420 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_09390 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_33720 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_21795 endonuclease K03746 hns; DNA-binding protein H-NS
F BJN34_22110 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_35870 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_36605 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F BJN34_0265 hypothetical protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BJN34_19660 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D BJN34_03300 recombinase RecA K03553 recA; recombination protein RecA
D BJN34_11635 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D BJN34_05970 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D BJN34_08700 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D BJN34_26980 damage-inducible protein K14160 imuA; protein ImuA
D BJN34_36650 translesion DNA synthesis-associated protein ImuA K14160 imuA; protein ImuA
D BJN34_26985 DNA polymerase Y family protein K14161 imuB; protein ImuB
D BJN34_36645 DNA polymerase K14161 imuB; protein ImuB
D BJN34_26990 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D BJN34_36640 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D BJN34_02455 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BJN34_37520 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BJN34_36910 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BJN34_03305 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D BJN34_19310 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D BJN34_07275 helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D BJN34_17480 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BJN34_0120 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BJN34_16295 aminotransferase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BJN34_17185 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BJN34_12195 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BJN34_17180 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024