+D GENES KO
#
KEGG Orthology (KO) - Campylobacter ureolyticus
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:cure00010]
D CUREO_1149 pgi; phosphoglucose isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D CUREO_1156 fbaA; fructose-bisphosphate aldolase, class IIA K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D CUREO_1386 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D CUREO_1388 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CUREO_1387 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D CUREO_1553 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D CUREO_0321 pykF; pyruvate kinase I K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CUREO_0514 por; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D CUREO_0781 oorA; 2-oxoglutarate:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D CUREO_0782 oorB; 2-oxoglutarate:acceptor oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_0351 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:cure00020]
D CUREO_0206 gltA; citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D CUREO_0859 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D CUREO_0776 icd; isocitrate dehydrogenase, monomeric K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D CUREO_0781 oorA; 2-oxoglutarate:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D CUREO_0782 oorB; 2-oxoglutarate:acceptor oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D CUREO_0783 oorC; 2-oxoglutarate:acceptor oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D CUREO_0780 oorD; 2-oxoglutarate:acceptor oxidoreductase, delta subunit K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D CUREO_0779 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D CUREO_0778 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D CUREO_0979 frdA; fumarate reductase, flavoprotein subunit K00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0978 frdB; fumarate reductase, iron-sulfur subunit K25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0980 frdC; fumarate reductase, cytochrome b subunit K25996 frdC; succinate dehydrogenase subunit C
D CUREO_0480 tartrate dehydratase/fumarate hydratase, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D CUREO_0481 tartrate dehydratase/fumarate hydratase, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_0756 pycA; pyruvate carboxylase, subunit A K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D CUREO_0320 pycB; pyruvate carboxylase, subunit B K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D CUREO_0351 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D CUREO_0514 por; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
C 00030 Pentose phosphate pathway [PATH:cure00030]
D CUREO_1149 pgi; phosphoglucose isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D CUREO_1207 rpe; ribulose phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D CUREO_0143 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D CUREO_1469 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D CUREO_1187 rpiB; allose-6-phosphate isomerase / ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_0293 prs; ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D CUREO_1156 fbaA; fructose-bisphosphate aldolase, class IIA K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions [PATH:cure00040]
D CUREO_0714 ugd; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1090 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1150 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D CUREO_1207 rpe; ribulose phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D CUREO_1080 hypothetical protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:cure00051]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_1080 hypothetical protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D CUREO_1156 fbaA; fructose-bisphosphate aldolase, class IIA K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D CUREO_1386 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D CUREO_1187 rpiB; allose-6-phosphate isomerase / ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism [PATH:cure00052]
D CUREO_1382 gne; UDP-GlcNAc/Glc 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D CUREO_1150 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00053 Ascorbate and aldarate metabolism [PATH:cure00053]
D CUREO_0714 ugd; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1090 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1091 UDP-glucuronate 5'-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:cure00500]
D CUREO_1150 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_1149 pgi; phosphoglucose isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:cure00520]
D CUREO_1052 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D CUREO_0070 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D CUREO_0699 glmU; fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D CUREO_0624 murA; UDP-N-acetylglucosamine enolpyruvoyl transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D CUREO_0201 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D CUREO_1089 UDP-glucose/GDP-mannose dehydrogenase family protein K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]
D CUREO_1368 pglF; UDP-N-acetylglucosamine C-6 dehydratase K15912 pglF; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]
D CUREO_1369 pglE; UDP-4-amino-4,6-dideoxy-alpha-D-N-acetyl-D-glucosamine transaminase K15910 pglE; UDP-N-acetylbacillosamine transaminase [EC:2.6.1.34]
D CUREO_1371 pglD; UDP-4-amino-4,6-dideoxy-alpha-D-N-acetyl-D-glucosamine N-acetyltransferase K15913 pglD; UDP-N-acetylbacillosamine N-acetyltransferase [EC:2.3.1.203]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_1150 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D CUREO_0714 ugd; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1090 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1382 gne; UDP-GlcNAc/Glc 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D CUREO_1091 UDP-glucuronate 5'-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D CUREO_1149 pgi; phosphoglucose isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00620 Pyruvate metabolism [PATH:cure00620]
D CUREO_0514 por; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D CUREO_0781 oorA; 2-oxoglutarate:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D CUREO_0782 oorB; 2-oxoglutarate:acceptor oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D CUREO_0875 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D CUREO_0874 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D CUREO_0321 pykF; pyruvate kinase I K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CUREO_0166 accA; acetyl-CoA carboxylase, carboxyltransferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D CUREO_0228 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D CUREO_0229 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D CUREO_0555 accD; acetyl-CoA carboxylase, carboxyltransferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_0954 metallo-beta-lactamase family protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D CUREO_0232 mez; malate oxidoreductase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D CUREO_0756 pycA; pyruvate carboxylase, subunit A K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D CUREO_0320 pycB; pyruvate carboxylase, subunit B K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_0480 tartrate dehydratase/fumarate hydratase, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D CUREO_0481 tartrate dehydratase/fumarate hydratase, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D CUREO_0979 frdA; fumarate reductase, flavoprotein subunit K00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0978 frdB; fumarate reductase, iron-sulfur subunit K25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0980 frdC; fumarate reductase, cytochrome b subunit K25996 frdC; succinate dehydrogenase subunit C
D CUREO_0351 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D CUREO_1363 leuA; 2-isopropylmalate synthase, bacterial type K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D CUREO_0643 putative phage exclusion protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:cure00630]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_0206 gltA; citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D CUREO_0859 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D CUREO_1168 gycolate oxidase, subunit GlcD-related protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D CUREO_1292 anaerobic glycerol-3-phosphate dehydrogenase K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14]
D CUREO_0097 katA; catalase K03781 katE; catalase [EC:1.11.1.6]
D CUREO_0513 hypothetical protein K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D CUREO_0638 hypothetical protein K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_1402 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D CUREO_1414 garK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D CUREO_0248 fdhF; formate dehydrogenase N, alpha subunit, selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D CUREO_0471 fdhA; formate dehydrogenase, alpha subunit, selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D CUREO_0472 fdhB; formate dehydrogenase N, beta subunit, iron-sulfur cluster subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D CUREO_0249 fdhG; formate dehydrogenase N, beta subunit, iron-sulfur cluster subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D CUREO_0473 fdhC; formate dehydrogenase, cytochrome b-556 subunit K00127 fdoI; formate dehydrogenase subunit gamma
D CUREO_0457 hydrogenase, cytochrome b subunit K00127 fdoI; formate dehydrogenase subunit gamma
D CUREO_1033 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
C 00640 Propanoate metabolism [PATH:cure00640]
D CUREO_0875 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D CUREO_0874 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D CUREO_0166 accA; acetyl-CoA carboxylase, carboxyltransferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D CUREO_0228 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D CUREO_0229 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D CUREO_0555 accD; acetyl-CoA carboxylase, carboxyltransferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D CUREO_0778 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D CUREO_0779 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D CUREO_0859 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
C 00650 Butanoate metabolism [PATH:cure00650]
D CUREO_0979 frdA; fumarate reductase, flavoprotein subunit K00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0978 frdB; fumarate reductase, iron-sulfur subunit K25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0980 frdC; fumarate reductase, cytochrome b subunit K25996 frdC; succinate dehydrogenase subunit C
D CUREO_0514 por; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D CUREO_0781 oorA; 2-oxoglutarate:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D CUREO_0782 oorB; 2-oxoglutarate:acceptor oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D CUREO_0873 ilvI; acetolactate synthase III, valine-sensitive, catalytic (large) subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D CUREO_0872 ilvH; acetolactate synthase III, valine-sensitive, regulatory (small) subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:cure00660]
D CUREO_0873 ilvI; acetolactate synthase III, valine-sensitive, catalytic (large) subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D CUREO_0872 ilvH; acetolactate synthase III, valine-sensitive, regulatory (small) subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D CUREO_0778 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D CUREO_0779 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D CUREO_1418 leuC; isopropylmalate isomerase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D CUREO_1038 leuD; isopropylmalate isomerase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D CUREO_1037 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism
D CUREO_1386 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:cure00190]
D CUREO_1586 nuoA; NADH:quinone oxidoreductase I, membrane subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D CUREO_1587 nuoB; NADH:quinone oxidoreductase I, chain B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D CUREO_1588 nuoC; NADH:quinone oxidoreductase I, chain C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D CUREO_1589 nuoD; NADH:quinone oxidoreductase I, chain D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D CUREO_1590 hypothetical protein K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D CUREO_1591 hypothetical protein K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D CUREO_1592 nuoG; NADH:quinone oxidoreductase I, chain G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D CUREO_1593 nuoH; NADH:quinone oxidoreductase I, membrane subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D CUREO_1594 nuoI; NADH:quinone oxidoreductase I, chain I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D CUREO_1595 nuoJ; NADH:quinone oxidoreductase I, membrane subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D CUREO_1596 nuoK; NADH:quinone oxidoreductase I, membrane subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D CUREO_1597 nuoL; NADH:quinone oxidoreductase I, membrane subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D CUREO_1598 nuoM; NADH:quinone oxidoreductase I, membrane subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D CUREO_1599 nuoN; NADH:quinone oxidoreductase I, membrane subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D CUREO_0979 frdA; fumarate reductase, flavoprotein subunit K00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0978 frdB; fumarate reductase, iron-sulfur subunit K25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0980 frdC; fumarate reductase, cytochrome b subunit K25996 frdC; succinate dehydrogenase subunit C
D CUREO_1316 petA; ubiquinol cytochrome c oxidoreductase PetABC, 2Fe-2S subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D CUREO_1315 petB; ubiquinol cytochrome c oxidoreductase PetABC, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D CUREO_1314 petC; ubiquinol cytochrome c oxidoreductase PetABC, membrane-bound cytochrome c subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D CUREO_0501 ccoN; cytochrome c oxidase CcoNOPQ, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D CUREO_0502 ccoO; cytochrome c oxidase CcoNOPQ, cbb3-type, membrane-bound monoheme cytochrome c subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D CUREO_0503 ccoQ; cytochrome c oxidase CcoNOPQ, cbb3-type, subunit IV K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D CUREO_0504 ccoP; cytochrome c oxidase CcoNOPQ, cbb3-type, membrane-bound monoheme cytochrome c subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III
D CUREO_0029 cioA; cyanide-insensitive cytochrome oxidase CioAB, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D CUREO_0028 cioB; cyanide-insensitive cytochrome oxidase CioAB, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D CUREO_0167 cccA; periplasmic monoheme cytochrome c553 K08738 CYC; cytochrome c
D CUREO_0540 atpA; ATP synthase, F1 complex, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D CUREO_0542 atpD; ATP synthase, F1 complex, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D CUREO_0541 atpG; ATP synthase, F1 complex, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D CUREO_0539 atpH; ATP synthase, F1 complex, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D CUREO_0543 atpC; ATP synthase, F1 complex, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D CUREO_1017 atpB; ATP synthase, F0 complex, a subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D CUREO_0537 atpF'; ATP synthase, F0 complex, b' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D CUREO_0538 atpF; ATP synthase, F0 complex, b subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D CUREO_0354 atpE; ATP synthase, F0 complex, c subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D CUREO_0936 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D CUREO_1172 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D CUREO_0577 ppk2; polyphosphate kinase 2 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:cure00710]
D CUREO_1387 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D CUREO_1388 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CUREO_1156 fbaA; fructose-bisphosphate aldolase, class IIA K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D CUREO_0143 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D CUREO_1187 rpiB; allose-6-phosphate isomerase / ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D CUREO_1386 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D CUREO_1207 rpe; ribulose phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D CUREO_1469 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D CUREO_0351 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D CUREO_0232 mez; malate oxidoreductase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:cure00720]
D CUREO_0514 por; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D CUREO_0756 pycA; pyruvate carboxylase, subunit A K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D CUREO_0320 pycB; pyruvate carboxylase, subunit B K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_0480 tartrate dehydratase/fumarate hydratase, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D CUREO_0481 tartrate dehydratase/fumarate hydratase, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D CUREO_0979 frdA; fumarate reductase, flavoprotein subunit K00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0978 frdB; fumarate reductase, iron-sulfur subunit K25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
D CUREO_0980 frdC; fumarate reductase, cytochrome b subunit K25996 frdC; succinate dehydrogenase subunit C
D CUREO_0779 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D CUREO_0778 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D CUREO_0781 oorA; 2-oxoglutarate:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D CUREO_0782 oorB; 2-oxoglutarate:acceptor oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D CUREO_0783 oorC; 2-oxoglutarate:acceptor oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D CUREO_0780 oorD; 2-oxoglutarate:acceptor oxidoreductase, delta subunit K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D CUREO_0776 icd; isocitrate dehydrogenase, monomeric K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D CUREO_0859 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D CUREO_0166 accA; acetyl-CoA carboxylase, carboxyltransferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D CUREO_0228 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D CUREO_0229 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D CUREO_0555 accD; acetyl-CoA carboxylase, carboxyltransferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D CUREO_1185 folD; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase / 5,10-methylene-tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D CUREO_0874 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D CUREO_0875 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00680 Methane metabolism [PATH:cure00680]
D CUREO_0248 fdhF; formate dehydrogenase N, alpha subunit, selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D CUREO_0471 fdhA; formate dehydrogenase, alpha subunit, selenocysteine-containing K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D CUREO_0472 fdhB; formate dehydrogenase N, beta subunit, iron-sulfur cluster subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D CUREO_0249 fdhG; formate dehydrogenase N, beta subunit, iron-sulfur cluster subunit K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D CUREO_0473 fdhC; formate dehydrogenase, cytochrome b-556 subunit K00127 fdoI; formate dehydrogenase subunit gamma
D CUREO_0457 hydrogenase, cytochrome b subunit K00127 fdoI; formate dehydrogenase subunit gamma
D CUREO_1402 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_1156 fbaA; fructose-bisphosphate aldolase, class IIA K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D CUREO_1658 molybdopterin-binding TMAO/DMSO reductase K07812 torZ; trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3]
D CUREO_1379 coenzyme F420 hydrogenase/dehydrogenase K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D CUREO_0875 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D CUREO_0874 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D CUREO_1553 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D CUREO_0363 serA; alpha-ketoglutarate reductase / D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D CUREO_1456 serC; phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D CUREO_1470 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 00910 Nitrogen metabolism [PATH:cure00910]
D CUREO_0747 napA; periplasmic nitrate reductase NapAB, large subunit K02567 napA; nitrate reductase (cytochrome) [EC:1.9.6.1]
D CUREO_0744 napB; periplasmic nitrate reductase NapAB, small subunit, periplasmic diheme cytochrome c550 protein K02568 napB; nitrate reductase (cytochrome), electron transfer subunit
D CUREO_0279 nrfA; formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit K03385 nrfA; nitrite reductase (cytochrome c-552) [EC:1.7.2.2]
D CUREO_0278 nrfH; tetraheme cytochrome c-type protein NrfH K15876 nrfH; cytochrome c nitrite reductase small subunit
D CUREO_0770 putative hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D CUREO_0942 npd; nitronate monooxygenase K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]
D CUREO_0304 hydrolase, carbon-nitrogen family K01501 E3.5.5.1; nitrilase [EC:3.5.5.1]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_1480 cynT; carbonic anhydrase beta K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:cure00920]
D CUREO_0565 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D CUREO_0205 cysQ; adenosine-3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D CUREO_1061 putative thiosulfate/polysulfide reductase, molybdenum-binding subunit K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D CUREO_0616 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D CUREO_1063 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D CUREO_0302 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:cure00061]
D CUREO_0166 accA; acetyl-CoA carboxylase, carboxyltransferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D CUREO_0228 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D CUREO_0229 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D CUREO_0555 accD; acetyl-CoA carboxylase, carboxyltransferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D CUREO_0164 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
D CUREO_0551 fabD; malonyl-CoA-[acp] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D CUREO_0162 fabH; beta-ketoacyl-[acp] synthase III (KASIII) K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D CUREO_0165 fabF; beta-ketoacyl-[acp] synthase II (KASII) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D CUREO_0163 fabG; 3-oxo-acyl-[acp] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D CUREO_0082 fabZ; 3-hydroxyacyl-[acp] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D CUREO_1385 fabI; enoyl-[acp] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:cure00071]
D CUREO_1437 aas; 2-acylglycerophosphoethanolamine acyltransferase / acyl-[acp] synthetase K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis [PATH:cure00121]
D CUREO_0896 short-chain dehydrogenase/reductase K00076 hdhA; 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:cure00561]
D CUREO_1414 garK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_0161 plsX; acyl phosphate synthase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D CUREO_1425 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D CUREO_0450 plsC; 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:cure00564]
D CUREO_1015 gpsA; glycerol 3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D CUREO_1425 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D CUREO_0450 plsC; 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D CUREO_1416 pldA; phospholipase A1 K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
D CUREO_1437 aas; 2-acylglycerophosphoethanolamine acyltransferase / acyl-[acp] synthetase K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
D CUREO_1420 cdsA; CDP-diglyceride synthetase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D CUREO_0897 pgsA; phosphatidylglycerophosphate synthase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D CUREO_0564 pgpA; phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
C 00565 Ether lipid metabolism [PATH:cure00565]
D CUREO_1416 pldA; phospholipase A1 K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
D CUREO_1416 pldA; phospholipase A1 K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
C 00591 Linoleic acid metabolism
D CUREO_1416 pldA; phospholipase A1 K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
C 00592 alpha-Linolenic acid metabolism [PATH:cure00592]
D CUREO_1416 pldA; phospholipase A1 K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]
C 01040 Biosynthesis of unsaturated fatty acids
D CUREO_1434 acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:cure00230]
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D CUREO_0293 prs; ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D CUREO_1664 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D CUREO_1575 purN; phosphoribosylglycinamide formyltransferase 1 K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D CUREO_1086 purL; phosphoribosylformylglycinamidine synthase PurLQS, PurL subunit K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D CUREO_0907 purS; phosphoribosylformylglycinamidine synthase PurLQS, PurS subunit K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D CUREO_0908 purQ; phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D CUREO_0074 purM; phosphoribosylformylglycinamide cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D CUREO_0375 purE; 5-aminoimidazole ribonucleotide (AIR) carboxylase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D CUREO_0906 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D CUREO_0042 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D CUREO_1084 purH; AICAR transformylase / IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D CUREO_1188 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D CUREO_1584 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D CUREO_1310 multi-copper polyphenol oxidoreductase laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D CUREO_0301 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D CUREO_0158 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D CUREO_0448 putative dITP/XTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D CUREO_1049 putative nucleotide phosphoribosyltransferase K00769 gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
D CUREO_0332 guaA; GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D CUREO_1305 gmk; deoxyguanylate kinase / guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D CUREO_0041 nrdA; aerobic ribonucleoside-diphosphate reductase Ia, B1 protein subunit NrdA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CUREO_0035 nrdB; aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D CUREO_0038 nrdD2; anaerobic ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D CUREO_0944 spoT; ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D CUREO_0364 exopolyphosphatase, Ppx/GppA family K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D CUREO_1429 gppA; guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D CUREO_0496 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D CUREO_0935 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D CUREO_0985 HIT family hydrolase, FHIT branch K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D CUREO_0565 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D CUREO_0016 ureC; urease, alpha subunit K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D CUREO_0015 ureB2; urease, beta subunit K01429 ureB; urease subunit beta [EC:3.5.1.5]
D CUREO_0014 ureA2; urease, gamma subunit K01430 ureA; urease subunit gamma [EC:3.5.1.5]
C 00240 Pyrimidine metabolism [PATH:cure00240]
D CUREO_0087 carB; carbamoylphosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D CUREO_0958 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D CUREO_0957 pyrC2; dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D CUREO_0893 pyrD; dihydroorotate dehydrogenase 2 K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D CUREO_1671 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D CUREO_1672 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D CUREO_0946 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D CUREO_0158 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D CUREO_0585 maf; septum formation protein Maf K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D CUREO_0031 pyrG; CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D CUREO_1584 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D CUREO_0234 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D CUREO_0038 nrdD2; anaerobic ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D CUREO_0209 dcd; dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D CUREO_0041 nrdA; aerobic ribonucleoside-diphosphate reductase Ia, B1 protein subunit NrdA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CUREO_0035 nrdB; aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D CUREO_0619 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D CUREO_1669 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D CUREO_0627 peptidase family M20/M25/M40, putative N-carbamoyl-L-amino acid amidohydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D CUREO_0857 short-chain dehydrogenase/reductase, subgroup 5 K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:cure00250]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_0914 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D CUREO_0056 ansB; asparaginase II K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D CUREO_0912 aspA; aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1]
D CUREO_0723 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D CUREO_0349 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D CUREO_0496 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D CUREO_0042 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D CUREO_0958 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_0087 carB; carbamoylphosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D CUREO_0908 purQ; phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D CUREO_1052 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D CUREO_1664 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:cure00260]
D CUREO_0807 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4]
D CUREO_0969 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D CUREO_1653 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D CUREO_0273 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D CUREO_1011 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D CUREO_1402 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D CUREO_1414 garK; glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D CUREO_1553 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D CUREO_0363 serA; alpha-ketoglutarate reductase / D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D CUREO_1456 serC; phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D CUREO_1470 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D CUREO_0857 short-chain dehydrogenase/reductase, subgroup 5 K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
D CUREO_0840 ilvA; threonine deaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D CUREO_0519 trpA; tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D CUREO_0520 trpB; tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:cure00270]
D CUREO_0616 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D CUREO_1063 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D CUREO_0292 metE; cobalamin-independent homocysteine transmethylase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D CUREO_1003 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D CUREO_0552 pfs; multifunctional 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase / 6-amino-6-deoxyfutalosine hydrolase K18284 K18284; adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30]
D CUREO_1310 multi-copper polyphenol oxidoreductase laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D CUREO_0203 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1163 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1430 luxS; S-ribosylhomocysteine lyase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D CUREO_1153 acd; 1-aminocyclopropane-1-carboxylate deaminase K01505 E3.5.99.7; 1-aminocyclopropane-1-carboxylate deaminase [EC:3.5.99.7]
D CUREO_0807 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4]
D CUREO_0969 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D CUREO_1653 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D CUREO_0302 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D CUREO_1065 metY; O-acetylhomoserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D CUREO_0079 ilvE; branched-chain amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_0777 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D CUREO_0363 serA; alpha-ketoglutarate reductase / D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D CUREO_1456 serC; phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00280 Valine, leucine and isoleucine degradation [PATH:cure00280]
D CUREO_0079 ilvE; branched-chain amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:cure00290]
D CUREO_0840 ilvA; threonine deaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D CUREO_1418 leuC; isopropylmalate isomerase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D CUREO_1038 leuD; isopropylmalate isomerase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D CUREO_1037 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D CUREO_0873 ilvI; acetolactate synthase III, valine-sensitive, catalytic (large) subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D CUREO_0872 ilvH; acetolactate synthase III, valine-sensitive, regulatory (small) subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D CUREO_0827 ilvC; acetohydroxy acid isomeroreductase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D CUREO_1665 ilvD; dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D CUREO_0079 ilvE; branched-chain amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D CUREO_1363 leuA; 2-isopropylmalate synthase, bacterial type K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D CUREO_0643 putative phage exclusion protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:cure00300]
D CUREO_1653 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D CUREO_0807 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4]
D CUREO_0969 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D CUREO_0895 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D CUREO_1663 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D CUREO_0569 dapD; tetrahydrodipicolinate succinylase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D CUREO_1023 argD; N-succinyldiaminopimelate-aminotransferase / acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D CUREO_0313 dapE; N-succinyl-diaminopimelate deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D CUREO_0072 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D CUREO_1464 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D CUREO_0139 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D CUREO_0881 murF; D-alanyl-D-alanine-adding enzyme K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:cure00310]
D CUREO_1075 D-amino acid aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:cure00220]
D CUREO_1295 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D CUREO_0723 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D CUREO_0349 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D CUREO_0016 ureC; urease, alpha subunit K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D CUREO_0015 ureB2; urease, beta subunit K01429 ureB; urease subunit beta [EC:3.5.1.5]
D CUREO_0014 ureA2; urease, gamma subunit K01430 ureA; urease subunit gamma [EC:3.5.1.5]
D CUREO_0908 purQ; phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_0087 carB; carbamoylphosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_0923 acetyltransferase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D CUREO_1204 argJ; bifunctional ornithine acetyltransferase / N-acetylglutamate synthase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D CUREO_1009 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D CUREO_1472 argC; N-acetyl-gamma-glutamylphosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D CUREO_1023 argD; N-succinyldiaminopimelate-aminotransferase / acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:cure00330]
D CUREO_0617 speA; arginine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19]
D CUREO_1194 aguA; agmatine deiminase K10536 aguA; agmatine deiminase [EC:3.5.3.12]
D CUREO_1138 aguB; N-carbamoylputrescine amidohydrolase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]
D CUREO_0468 nspC; carboxynorspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1075 D-amino acid aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00340 Histidine metabolism [PATH:cure00340]
D CUREO_1392 hisG(S); ATP phosphoribosyltransferase HisG(S)Z, hetero-octameric short form, catalytic subunit K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D CUREO_0077 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
D CUREO_1366 hisA; N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D CUREO_0046 hisF; imidazole glycerol phosphate synthase HisFH, HisF subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D CUREO_0928 hisB; imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D CUREO_1152 hisD; histidinal dehydrogenase / histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00350 Tyrosine metabolism [PATH:cure00350]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00360 Phenylalanine metabolism [PATH:cure00360]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D CUREO_1075 D-amino acid aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00380 Tryptophan metabolism [PATH:cure00380]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_0304 hydrolase, carbon-nitrogen family K01501 E3.5.5.1; nitrilase [EC:3.5.5.1]
D CUREO_0097 katA; catalase K03781 katE; catalase [EC:1.11.1.6]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:cure00400]
D CUREO_0915 aroG; 2-dehydro-3-deoxyphosphoheptonate aldolase (DAHP synthetase, class II) K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D CUREO_0763 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D CUREO_0287 aroD; 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D CUREO_1404 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D CUREO_1357 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D CUREO_0360 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D CUREO_1509 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D CUREO_0522 trpD; anthranilate phosphoribosyltransferase / anthranilate synthase component II K13497 trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18]
D CUREO_0521 trpF; phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D CUREO_0986 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D CUREO_0519 trpA; tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D CUREO_0520 trpB; tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D CUREO_1463 pheA; chorismate mutase / prephenate dehydratase K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
D CUREO_0269 tyrA; chorismate mutase / prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:cure00410]
D CUREO_0140 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D CUREO_1409 panC; pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D CUREO_0627 peptidase family M20/M25/M40, putative N-carbamoyl-L-amino acid amidohydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C 00430 Taurine and hypotaurine metabolism [PATH:cure00430]
D CUREO_0874 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D CUREO_0875 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:cure00450]
D CUREO_0292 metE; cobalamin-independent homocysteine transmethylase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D CUREO_1656 trxB; thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D CUREO_0990 NADPH oxidoreductase, putative flavodoxin quinone reductase FqrB K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D CUREO_0565 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D CUREO_0477 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D CUREO_0240 selA; selenocysteine synthase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D CUREO_0675 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:cure00460]
D CUREO_0304 hydrolase, carbon-nitrogen family K01501 E3.5.5.1; nitrilase [EC:3.5.5.1]
D CUREO_0056 ansB; asparaginase II K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D CUREO_1402 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:cure00470]
D CUREO_1209 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D CUREO_1075 D-amino acid aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D CUREO_0884 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D CUREO_0908 purQ; phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D CUREO_1551 murD; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D CUREO_0914 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D CUREO_0072 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D CUREO_1464 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:cure00480]
D CUREO_1190 leucyl aminopeptidase, peptidase M17 family K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D CUREO_1160 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D CUREO_0776 icd; isocitrate dehydrogenase, monomeric K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis [PATH:cure00540]
D CUREO_0083 lpxA; UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D CUREO_0271 lpxC; UDP-3-O-acyl-N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D CUREO_0871 lpxD; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D CUREO_1471 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D CUREO_1474 lpxB; lipid A disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D CUREO_1007 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D CUREO_0050 kpsF; D-arabinose 5-phosphate isomerase K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D CUREO_1353 kdsA; 3-deoxy-D-manno-octulosonate 8-phosphate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D CUREO_0927 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]
D CUREO_1012 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D CUREO_0379 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D CUREO_1093 waaM; lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D CUREO_1105 gmhA; sedoheptulose 7-phosphate isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D CUREO_1106 waaE; D,D-heptose 1-phosphate adenosyltransferase / 7-phosphate kinase K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]
D CUREO_1108 gmhB; D,D-heptose 1,7-bisphosphate phosphatase K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D CUREO_1107 waaD; ADP-L-glycero-D-mannoheptose-6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D CUREO_1092 waaC; heptosyltransferase I K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D CUREO_1104 waaF; heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D CUREO_1095 waaQ; heptosyltransferase III K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]
D CUREO_1103 glycosyltransferase, family 1 K02844 waaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]
D CUREO_1102 O-antigen ligase family protein K02847 waaL; O-antigen ligase [EC:2.4.99.26]
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:cure00541]
D CUREO_1150 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D CUREO_1382 gne; UDP-GlcNAc/Glc 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D CUREO_0714 ugd; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1090 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D CUREO_1091 UDP-glucuronate 5'-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D CUREO_0699 glmU; fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D CUREO_1368 pglF; UDP-N-acetylglucosamine C-6 dehydratase K15912 pglF; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]
D CUREO_1089 UDP-glucose/GDP-mannose dehydrogenase family protein K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]
C 00550 Peptidoglycan biosynthesis [PATH:cure00550]
D CUREO_0624 murA; UDP-N-acetylglucosamine enolpyruvoyl transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D CUREO_0201 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D CUREO_0309 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D CUREO_1551 murD; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D CUREO_0139 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D CUREO_0884 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D CUREO_0881 murF; D-alanyl-D-alanine-adding enzyme K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D CUREO_0697 ispU; undecaprenyl diphosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D CUREO_1327 bacA; undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D CUREO_1552 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D CUREO_0739 murG; N-acetylglucosaminyl transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D CUREO_0584 pbpA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D CUREO_0614 pbpC; penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D CUREO_0921 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D CUREO_0590 ftsI; cell division protein FtsI / penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis [PATH:cure00552]
D CUREO_1327 bacA; undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:cure00543]
D CUREO_0616 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:cure00730]
D CUREO_0596 thiC; thiamine biosynthesis protein K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D CUREO_0196 thiD; hydroxymethylpyrimidine kinase / phosphohydroxymethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D CUREO_0837 hydroxymethylpyrimidine kinase / phosphohydroxymethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D CUREO_1568 iscS; cysteine desulfurase/aminotransferase (IscS/NifS) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CUREO_0574 thiH; ThiGH complex, tyrosine lyase subunit ThiH K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]
D CUREO_0458 [FeFe] hydrogenase H-cluster radical SAM maturase HydG K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]
D CUREO_1461 dxs; 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D CUREO_0573 thiG; ThiGH complex, thiazole synthase subunit ThiG K03149 thiG; thiazole synthase [EC:2.8.1.10]
D CUREO_0492 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D CUREO_0575 thiamin phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D CUREO_1326 thiE; thiamin phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D CUREO_0994 thiL; thiamine monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D CUREO_0103 phoA; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D CUREO_0935 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:cure00740]
D CUREO_1297 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D CUREO_0984 ribAB; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II protein K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D CUREO_0281 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D CUREO_1350 ribH; 6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase, beta subunit) K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D CUREO_1311 ribE; 6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase, alpha subunit) K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D CUREO_0800 ribF; bifunctional riboflavin kinase / FMN adenylyltransferase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D CUREO_0492 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D CUREO_0621 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:cure00750]
D CUREO_1456 serC; phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D CUREO_1011 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D CUREO_0372 pdxS; pyridoxal 5'-phosphate synthase PdxST, synthase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:cure00760]
D CUREO_0233 pncBI; nicotinate phosphoribosyltransferase, subgroup A K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D CUREO_1584 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D CUREO_1389 nadD_rsfS; fused nicotinate-mononucleotide adenylyltransferase / ribosomal silencing factor K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D CUREO_1005 nadE; NAD synthetase, NH3-dependent K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D CUREO_0298 cinA; competence/damage-inducible domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D CUREO_0195 pncA; pyrazinamidase / nicotinamidase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-]
D CUREO_0933 ppnK; inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:cure00770]
D CUREO_0873 ilvI; acetolactate synthase III, valine-sensitive, catalytic (large) subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D CUREO_0872 ilvH; acetolactate synthase III, valine-sensitive, regulatory (small) subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D CUREO_0827 ilvC; acetohydroxy acid isomeroreductase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D CUREO_1665 ilvD; dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D CUREO_1134 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D CUREO_1409 panC; pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D CUREO_1393 coaX; pantothenate kinase, type III K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D CUREO_0698 dfp; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D CUREO_0620 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D CUREO_0073 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D CUREO_0411 acpS; holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D CUREO_0079 ilvE; branched-chain amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D CUREO_0627 peptidase family M20/M25/M40, putative N-carbamoyl-L-amino acid amidohydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D CUREO_0140 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:cure00780]
D CUREO_0165 fabF; beta-ketoacyl-[acp] synthase II (KASII) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D CUREO_0163 fabG; 3-oxo-acyl-[acp] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D CUREO_0082 fabZ; 3-hydroxyacyl-[acp] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D CUREO_1385 fabI; enoyl-[acp] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D CUREO_0369 bioAD; bifunctional 7,8-diaminopelargonic acid synthase / dethiobiotin synthetase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D CUREO_0459 [FeFe] hydrogenase H-cluster radical SAM maturase HydE K01012 bioB; biotin synthase [EC:2.8.1.6]
D CUREO_1312 bioB; biotin synthetase K01012 bioB; biotin synthase [EC:2.8.1.6]
D CUREO_0534 birA; biotin-[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism
C 00790 Folate biosynthesis [PATH:cure00790]
D CUREO_1569 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D CUREO_0377 hypothetical protein K22391 E3.5.4.16; GTP cyclohydrolase I [EC:3.5.4.16]
D CUREO_0103 phoA; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D CUREO_0289 folK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D CUREO_0804 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D CUREO_0426 folC; bifunctional folypolyglutamate synthetase / dihydrofolate synthetase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D CUREO_1297 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D CUREO_0984 ribAB; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II protein K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D CUREO_1644 queD; 6-carboxy-5,6,7,8-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D CUREO_1643 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D CUREO_0663 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D CUREO_0005 queF; 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D CUREO_1642 moaA; molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D CUREO_0146 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D CUREO_0466 moaE; molybdopterin synthase, large subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D CUREO_0759 mogA; molybdopterin adenylyltransferase K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
D CUREO_0623 moeA2; molybdenum::molybdopterin ligase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D CUREO_0465 moeA1; molybdenum::molybdopterin ligase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D CUREO_1417 mobA; molybdenum cofactor guanylyltransferase protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:cure00670]
D CUREO_1185 folD; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase / 5,10-methylene-tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D CUREO_1402 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D CUREO_1575 purN; phosphoribosylglycinamide formyltransferase 1 K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D CUREO_1084 purH; AICAR transformylase / IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D CUREO_0532 fmt; 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D CUREO_1669 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D CUREO_1033 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D CUREO_1143 5,10-methenyltetrahydrofolate synthetase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:cure00860]
D CUREO_0231 gltX2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CUREO_0641 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D CUREO_1183 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D CUREO_1296 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D CUREO_0644 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D CUREO_0340 hemD; uroporphyrinogen III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D CUREO_0966 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D CUREO_1293 hemN2; oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]
D CUREO_0992 hemG; protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
D CUREO_0589 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D CUREO_1662 heme oxygenase, HugZ family K07226 hutZ; heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:cure00130]
D CUREO_1640 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D CUREO_0645 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D CUREO_0621 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D CUREO_1458 ubiE; bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / S-adenosylmethionine:2-DMK methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D CUREO_0236 mqnA2; 6-amino-6-deoxyfutalosine synthase K11782 mqnA; chorismate dehydratase [EC:4.2.1.151]
D CUREO_1051 menaquinone biosynthesis protein, SCO4494 family K18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]
D CUREO_0286 metallo-dependent hydrolase, subgroup D K20810 mqnX; aminodeoxyfutalosine deaminase [EC:3.5.4.40]
D CUREO_0552 pfs; multifunctional 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase / 6-amino-6-deoxyfutalosine hydrolase K18284 K18284; adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30]
D CUREO_1176 mqnC; dehypoxanthinylfutalosine cyclase K11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]
D CUREO_0200 mqnD; 1,4-dihydroxy-6-naphthoate synthase K11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:cure00900]
D CUREO_1461 dxs; 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D CUREO_1421 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D CUREO_0567 ispDF; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein K12506 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]
D CUREO_0601 ispE; 4-diphosphocytidyl-2-C-methylerythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D CUREO_0835 ispG; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D CUREO_0361 ispH; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D CUREO_0621 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D CUREO_0142 ispA; geranyl diphosphate synthase / farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D CUREO_0640 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D CUREO_0697 ispU; undecaprenyl diphosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D CUREO_0143 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures [PATH:cure01054]
D CUREO_0914 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:cure00261]
D CUREO_0565 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D CUREO_0807 lysC; aspartokinase, alpha and beta subunits K00928 lysC; aspartate kinase [EC:2.7.2.4]
D CUREO_0969 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D CUREO_0895 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D CUREO_1663 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
D CUREO_0708 phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis [PATH:cure00401]
D CUREO_0269 tyrA; chorismate mutase / prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
D CUREO_0551 fabD; malonyl-CoA-[acp] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D CUREO_0163 fabG; 3-oxo-acyl-[acp] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D CUREO_1385 fabI; enoyl-[acp] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D CUREO_0164 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:cure00999]
D CUREO_1003 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D CUREO_1404 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
D CUREO_0295 tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00627 Aminobenzoate degradation [PATH:cure00627]
D CUREO_0304 hydrolase, carbon-nitrogen family K01501 E3.5.5.1; nitrilase [EC:3.5.5.1]
D CUREO_0621 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:cure00625]
D CUREO_1291 aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
D CUREO_0295 tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
D CUREO_0304 hydrolase, carbon-nitrogen family K01501 E3.5.5.1; nitrilase [EC:3.5.5.1]
C 00791 Atrazine degradation
D CUREO_0016 ureC; urease, alpha subunit K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D CUREO_0015 ureB2; urease, beta subunit K01429 ureB; urease subunit beta [EC:3.5.1.5]
D CUREO_0014 ureA2; urease, gamma subunit K01430 ureA; urease subunit gamma [EC:3.5.1.5]
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
D CUREO_0295 tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:cure03020]
D CUREO_1277 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D CUREO_1276 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D CUREO_0135 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D CUREO_0945 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:cure03010]
D CUREO_0362 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D CUREO_1309 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D CUREO_0115 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D CUREO_0134 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D CUREO_0126 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D CUREO_0830 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D CUREO_1272 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D CUREO_0123 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D CUREO_0511 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D CUREO_0108 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D CUREO_0133 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D CUREO_1273 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D CUREO_0132 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D CUREO_0122 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D CUREO_0798 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D CUREO_0382 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D CUREO_0118 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D CUREO_0832 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D CUREO_0113 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D CUREO_0069 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D CUREO_1489 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D CUREO_1280 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D CUREO_0112 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D CUREO_0109 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D CUREO_0110 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D CUREO_0121 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D CUREO_0124 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D CUREO_1278 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D CUREO_0724 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D CUREO_1279 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D CUREO_1281 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D CUREO_0510 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D CUREO_0119 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D CUREO_0127 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D CUREO_0116 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D CUREO_0136 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D CUREO_0125 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D CUREO_0386 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D CUREO_0075 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D CUREO_0529 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D CUREO_0114 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D CUREO_0111 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D CUREO_0120 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D CUREO_1467 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D CUREO_0530 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D CUREO_1206 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D CUREO_0117 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D CUREO_1647 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D CUREO_0160 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D CUREO_1285 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D CUREO_1114 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D CUREO_0076 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D CUREO_0131 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D CUREO_0485 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_1560 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0631 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0488 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_1557 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_0634 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_0489 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_0635 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_1556 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:cure00970]
D CUREO_0486 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_0632 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1559 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1447 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1269 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_1497 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_0755 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_1498 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_0956 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D CUREO_1341 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D CUREO_1444 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D CUREO_0692 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D CUREO_0579 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D CUREO_1339 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1067 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1521 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1446 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_0622 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_1288 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_1496 tRNA-His K14226 tRNA-His; tRNA His
D CUREO_0487 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_1558 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_0633 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_0355 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_0752 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1445 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1499 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1066 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D CUREO_1340 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D CUREO_1525 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_0691 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_1476 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_1550 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D CUREO_1495 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D CUREO_0145 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1347 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1442 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1287 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D CUREO_1290 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D CUREO_1284 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D CUREO_1289 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D CUREO_1342 tRNA-Val K14237 tRNA-Val; tRNA Val
D CUREO_1515 tRNA-Val K14237 tRNA-Val; tRNA Val
D CUREO_0231 gltX2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CUREO_0668 gltX1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D CUREO_0300 gatA; Glu-tRNA(Gln) amidotransferase, subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D CUREO_1016 gatB; Glu-tRNA(Gln) amidotransferase, subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D CUREO_1397 gatC; Glu-tRNA(Gln) amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D CUREO_0587 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D CUREO_0934 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CUREO_0376 glyQ; glycyl-tRNA synthetase, alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D CUREO_1030 glyS; glycyl-tRNA synthetase, beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D CUREO_1523 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D CUREO_1361 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D CUREO_0240 selA; selenocysteine synthase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D CUREO_0891 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D CUREO_0675 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D CUREO_0532 fmt; 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D CUREO_0612 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D CUREO_0424 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CUREO_0299 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D CUREO_1401 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D CUREO_1303 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CUREO_0642 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D CUREO_0618 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0495 hisZ; ATP phosphoribosyltransferase HisG(S)Z, hetero-octameric short form, regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0358 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D CUREO_0359 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D CUREO_0943 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CUREO_1358 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:cure03060]
D CUREO_0128 secY; preprotein translocase SecYEG, SecY subunit K03076 secY; preprotein translocase subunit SecY
D CUREO_1283 secE; preprotein translocase SecYEG, SecE subunit K03073 secE; preprotein translocase subunit SecE
D CUREO_1455 secG; preprotein translocase SecYEG, SecG subunit K03075 secG; preprotein translocase subunit SecG
D CUREO_0421 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D CUREO_0422 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D CUREO_0420 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D CUREO_1111 oxaA; 60 kDa inner-membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CUREO_0750 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D CUREO_0381 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D CUREO_1145 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D CUREO_1304 putative twin arginine-targeting protein translocase, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D CUREO_0810 Sec-independent protein translocase protein K03117 tatB; sec-independent protein translocase protein TatB
D CUREO_0811 tatC; Sec-independent protein secretion pathway component K03118 tatC; sec-independent protein translocase protein TatC
D CUREO_1186 lepB; leader peptidase (signal peptidase I) K03100 lepB; signal peptidase I [EC:3.4.21.89]
D CUREO_0071 lspA; prolipoprotein signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:cure04122]
D CUREO_1568 iscS; cysteine desulfurase/aminotransferase (IscS/NifS) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CUREO_0291 mnmA; tRNA U34 2-thiouridylase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D CUREO_1504 putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D CUREO_0466 moaE; molybdopterin synthase, large subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D CUREO_1642 moaA; molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D CUREO_0467 moaD; molybdopterin synthase, small subunit K03636 moaD; sulfur-carrier protein
D CUREO_0305 ThiF family protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D CUREO_0146 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D CUREO_0759 mogA; molybdopterin adenylyltransferase K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
D CUREO_0571 thiS; thiamin biosynthesis protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome
C 03018 RNA degradation [PATH:cure03018]
D CUREO_0808 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D CUREO_0345 pnp; polynucleotide phosphorylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D CUREO_0828 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D CUREO_0057 ATP-dependent DNA helicase (RecQ/UvrD domains) K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D CUREO_0171 rho; transcription termination factor K03628 rho; transcription termination factor Rho
D CUREO_1142 ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-]
D CUREO_0048 mRNA degradation ribonuclease J1/J2 (metallo-beta-lactamase superfamily) K12574 rnj; ribonuclease J [EC:3.1.-.-]
D CUREO_0657 dnaK; chaperone and heat shock protein 70 K04043 dnaK; molecular chaperone DnaK
D CUREO_0768 groEL; 60 kD chaperonin (cpn60) K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CUREO_1172 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D CUREO_0577 ppk2; polyphosphate kinase 2 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:cure03030]
D CUREO_1208 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D CUREO_1333 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D CUREO_0173 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D CUREO_0805 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D CUREO_0829 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D CUREO_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D CUREO_0834 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D CUREO_1505 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1507 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D CUREO_0106 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:cure03410]
D CUREO_1158 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D CUREO_1483 ung; uracil-DNA glycosylase, family 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D CUREO_1118 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D CUREO_0265 xth; exodeoxyribonuclease III (exonuclease III) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D CUREO_1519 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D CUREO_0032 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:cure03420]
D CUREO_0428 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D CUREO_0524 uvrA; UvrABC nucleotide excision repair complex, subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D CUREO_0560 uvrB; UvrABC nucleotide excision repair complex, subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D CUREO_0330 uvrC; UvrABC nucleotide excision repair complex, subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D CUREO_0603 UvrD/REP family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_0693 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:cure03430]
D CUREO_0311 mutS2; DNA mismatch binding protein, MutS2 family K07456 mutS2; DNA mismatch repair protein MutS2
D CUREO_0603 UvrD/REP family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_0693 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_1457 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D CUREO_0303 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D CUREO_0032 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1333 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D CUREO_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D CUREO_0173 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D CUREO_0829 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D CUREO_0805 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D CUREO_1208 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:cure03440]
D CUREO_0032 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0322 recR; recombination protein K06187 recR; recombination protein RecR
D CUREO_0199 recA; recombinase K03553 recA; recombination protein RecA
D CUREO_0885 ruvA; RuvABC resolvasome, subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D CUREO_0976 ruvB; RuvABC resolvasome, subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D CUREO_1673 ruvC; RuvABC resolvasome, subunit RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D CUREO_1174 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D CUREO_0509 addA; exonuclease V, helicase AddA K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D CUREO_1333 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D CUREO_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D CUREO_0173 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D CUREO_0829 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D CUREO_0805 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D CUREO_1208 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D CUREO_0664 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:cure02010]
D CUREO_0583 tupA; tungsten ABC transporter TupABC, periplasmic tungstate-binding protein K05772 tupA; tungstate transport system substrate-binding protein
D CUREO_0582 tupB; tungsten ABC transporter TupABC, permease protein K05773 tupB; tungstate transport system permease protein
D CUREO_0581 tupC; tungsten ABC transporter TupABC, ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D CUREO_0191 modA; molybdenum ABC transporter ModABC, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D CUREO_0193 modB; molybdenum ABC transporter ModABC, permease protein K02018 modB; molybdate transport system permease protein
D CUREO_0194 modC; molybdenum ABC transporter ModABC, ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D CUREO_0648 iron ABC transporter, periplasmic iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D CUREO_0649 iron ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D CUREO_0650 iron ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D CUREO_0887 lipid asymmetry ABC-type transporter Mla, periplasmic component MlaD K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D CUREO_0889 lipid asymmetry ABC-type transporter Mla, permease component MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D CUREO_0888 lipid asymmetry ABC-type transporter Mla, ATPase component MlaF K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D CUREO_1124 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_1129 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_1128 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D CUREO_1127 pstA; phosphate ABC transporter, permease protein K02038 pstA; phosphate transport system permease protein
D CUREO_1126 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D CUREO_1325 amino acid ABC transporter, periplasmic substrate-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D CUREO_1322 amino acid ABC transporter, permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein
D CUREO_1323 amino acid ABC transporter, ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D CUREO_0679 metQ; DL-methionine ABC transporter MetINQ, substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein
D CUREO_0607 metI; DL-methionine ABC transporter MetINQ, permease protein K02072 metI; D-methionine transport system permease protein
D CUREO_0608 metN; DL-methionine ABC transporter MetINQ, ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein
D CUREO_0060 znuA; zinc ABC transporter ZnuABC, periplasmic zinc-binding protein K09815 znuA; zinc transport system substrate-binding protein
D CUREO_0063 znuB; zinc ABC transporter ZnuABC, membrane protein K09816 znuB; zinc transport system permease protein
D CUREO_0062 znuC; zinc ABC transporter ZnuABC, ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D CUREO_0400 hypothetical protein K10094 cbiK; nickel transport protein
D CUREO_0695 putative lipooligosaccharide transport system, permease component (LptF family) K07091 lptF; lipopolysaccharide export system permease protein
D CUREO_1465 putative lipooligosaccharide transport system, permease component (LptG family) K11720 lptG; lipopolysaccharide export system permease protein
D CUREO_0720 putative lipooligosaccharide transport system, ATP-binding component (LptB family) K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D CUREO_0948 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D CUREO_0949 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D CUREO_0338 ABC transporter, ATP-binding protein/permease K14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA/YbtP [EC:7.-.-.-]
D CUREO_0337 ABC transporter, ATP-binding protein/permease K14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB/YbtQ [EC:7.-.-.-]
D CUREO_0892 msbA; lipid A export ATP-binding/permease protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D CUREO_1544 type I secretion system, ABC transporter, HlyB family K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D CUREO_0707 macB; macrolide-specific efflux protein, ATP-binding/permease protein MacB K05685 macB; macrolide transport system ATP-binding/permease protein [EC:7.6.2.-]
D CUREO_0217 ABC transporter, ATP-binding/permease protein K06159 yojI; multidrug/microcin transport system ATP-binding/permease protein
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:cure03070]
D CUREO_1541 type I secretion system, membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D CUREO_1544 type I secretion system, ABC transporter, HlyB family K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D CUREO_0688 type II and III secretion system protein K02453 gspD; general secretion pathway protein D
D CUREO_0731 ctsD; transformation system, type II secretion system secretin protein CtsD K02453 gspD; general secretion pathway protein D
D CUREO_0736 ctsF; transformation system, type II secretion system membrane protein CtsF K02455 gspF; general secretion pathway protein F
D CUREO_0665 putative secretion system protein K02456 gspG; general secretion pathway protein G
D CUREO_0666 putative secretion system protein K02456 gspG; general secretion pathway protein G
D CUREO_0421 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D CUREO_0422 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D CUREO_1283 secE; preprotein translocase SecYEG, SecE subunit K03073 secE; preprotein translocase subunit SecE
D CUREO_1455 secG; preprotein translocase SecYEG, SecG subunit K03075 secG; preprotein translocase subunit SecG
D CUREO_0128 secY; preprotein translocase SecYEG, SecY subunit K03076 secY; preprotein translocase subunit SecY
D CUREO_0420 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D CUREO_1111 oxaA; 60 kDa inner-membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CUREO_0750 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D CUREO_1145 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D CUREO_0381 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D CUREO_1304 putative twin arginine-targeting protein translocase, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D CUREO_0810 Sec-independent protein translocase protein K03117 tatB; sec-independent protein translocase protein TatB
D CUREO_0811 tatC; Sec-independent protein secretion pathway component K03118 tatC; sec-independent protein translocase protein TatC
D CUREO_1343 lytic transglycosylase K03194 virB1; type IV secretion system protein VirB1
D CUREO_1620 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D CUREO_1622 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D CUREO_1624 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:cure02020]
D CUREO_1131 two-component system response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
D CUREO_0103 phoA; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D CUREO_1124 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_1129 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D CUREO_0479 dcuB; anaerobic C4-dicarboxylate transporter K07792 dcuB; anaerobic C4-dicarboxylate transporter DcuB
D CUREO_0328 two-component system, sensor histidine kinase (NIT sensor domain) K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_0242 two-component system sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
D CUREO_0786 hydC; [NiFe] hydrogenase, cytochrome b subunit K03620 hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit
D CUREO_1316 petA; ubiquinol cytochrome c oxidoreductase PetABC, 2Fe-2S subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D CUREO_1315 petB; ubiquinol cytochrome c oxidoreductase PetABC, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D CUREO_1314 petC; ubiquinol cytochrome c oxidoreductase PetABC, membrane-bound cytochrome c subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D CUREO_0167 cccA; periplasmic monoheme cytochrome c553 K08738 CYC; cytochrome c
D CUREO_0501 ccoN; cytochrome c oxidase CcoNOPQ, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D CUREO_0502 ccoO; cytochrome c oxidase CcoNOPQ, cbb3-type, membrane-bound monoheme cytochrome c subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D CUREO_0503 ccoQ; cytochrome c oxidase CcoNOPQ, cbb3-type, subunit IV K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D CUREO_0504 ccoP; cytochrome c oxidase CcoNOPQ, cbb3-type, membrane-bound monoheme cytochrome c subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III
D CUREO_0029 cioA; cyanide-insensitive cytochrome oxidase CioAB, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D CUREO_0028 cioB; cyanide-insensitive cytochrome oxidase CioAB, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D CUREO_1316 petA; ubiquinol cytochrome c oxidoreductase PetABC, 2Fe-2S subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:cure02024]
D CUREO_1430 luxS; S-ribosylhomocysteine lyase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D CUREO_0915 aroG; 2-dehydro-3-deoxyphosphoheptonate aldolase (DAHP synthetase, class II) K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D CUREO_1297 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D CUREO_0281 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D CUREO_1494 cmeC; multidrug efflux system CmeABC, outer membrane lipoprotein CmeC K18139 oprM; outer membrane protein, multidrug efflux system
D CUREO_1111 oxaA; 60 kDa inner-membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CUREO_1283 secE; preprotein translocase SecYEG, SecE subunit K03073 secE; preprotein translocase subunit SecE
D CUREO_1455 secG; preprotein translocase SecYEG, SecG subunit K03075 secG; preprotein translocase subunit SecG
D CUREO_0128 secY; preprotein translocase SecYEG, SecY subunit K03076 secY; preprotein translocase subunit SecY
D CUREO_0420 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D CUREO_0750 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D CUREO_1145 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D CUREO_0381 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
D CUREO_1154 putative membrane protein (OmpA/MotB domain) K02557 motB; chemotaxis protein MotB
C 02040 Flagellar assembly [PATH:cure02040]
D CUREO_1154 putative membrane protein (OmpA/MotB domain) K02557 motB; chemotaxis protein MotB
D CUREO_1044 rpoD; RNA polymerase sigma70 factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:cure01501]
D CUREO_1492 cmeA; multidrug efflux system CmeABC, periplasmic fusion protein CmeA K03585 acrA; membrane fusion protein, multidrug efflux system
D CUREO_1493 cmeB; multidrug efflux system CmeABC, inner membrane drug transporter CmeB K18138 acrB; multidrug efflux pump
D CUREO_1494 cmeC; multidrug efflux system CmeABC, outer membrane lipoprotein CmeC K18139 oprM; outer membrane protein, multidrug efflux system
D CUREO_0584 pbpA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D CUREO_0921 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D CUREO_0590 ftsI; cell division protein FtsI / penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:cure01502]
D CUREO_0884 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D CUREO_1209 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D CUREO_0881 murF; D-alanyl-D-alanine-adding enzyme K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D CUREO_1552 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D CUREO_0739 murG; N-acetylglucosaminyl transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:cure01503]
D CUREO_1543 hypothetical protein K01406 prtC; serralysin [EC:3.4.24.40]
D CUREO_0941 amiA; N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D CUREO_1492 cmeA; multidrug efflux system CmeABC, periplasmic fusion protein CmeA K03585 acrA; membrane fusion protein, multidrug efflux system
D CUREO_1493 cmeB; multidrug efflux system CmeABC, inner membrane drug transporter CmeB K18138 acrB; multidrug efflux pump
D CUREO_0083 lpxA; UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:cure01000]
C 01001 Protein kinases [BR:cure01001]
D CUREO_1025 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1074 cprS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_0323 racS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1428 cosS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1056 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_0328 two-component system, sensor histidine kinase (NIT sensor domain) K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
D CUREO_0242 two-component system sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:cure01009]
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D CUREO_1470 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:cure01002]
D CUREO_0071 lspA; prolipoprotein signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
D CUREO_0696 peptidase A24 N-terminal domain protein, putative prepilin signal peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D CUREO_0787 hydD; [NiFe] hydrogenase maturation protease HydD K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D CUREO_0332 guaA; GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D CUREO_1664 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D CUREO_1052 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D CUREO_1335 DJ-1/PfpI family protein (DUF4066 domain) K03152 thiJ; protein deglycase [EC:3.5.1.124]
D CUREO_0464 hypothetical protein K07052 K07052; CAAX protease family protein
D CUREO_0605 pepF; oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D CUREO_1543 hypothetical protein K01406 prtC; serralysin [EC:3.4.24.40]
D CUREO_0365 Zn-dependent peptidase, M16 family K07263 pqqL; zinc protease [EC:3.4.24.-]
D CUREO_1190 leucyl aminopeptidase, peptidase M17 family K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D CUREO_0313 dapE; N-succinyl-diaminopimelate deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D CUREO_1502 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
D CUREO_1160 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D CUREO_1510 peptidase family M20/M25/M40, putative N-carbamoyl-L-amino acid amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A
D CUREO_0129 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D CUREO_0288 pepQ; X-Pro dipeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D CUREO_1274 isoaspartyl dipeptidase K01305 iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]
D CUREO_1364 ftsH2; integral membrane ATP-dependent zinc metallopeptidase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D CUREO_0760 ftsH1; integral membrane ATP-dependent zinc metallopeptidase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D CUREO_1439 htpX; heat shock protein HtpX, M48 family peptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D CUREO_0898 RseP-like zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D CUREO_1571 clpP; ATP-dependent ClpAP/ClpXP protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D CUREO_1201 lon; DNA-binding, ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D CUREO_1186 lepB; leader peptidase (signal peptidase I) K03100 lepB; signal peptidase I [EC:3.4.21.89]
D CUREO_0905 ctpA; carboxyl-terminal protease family protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D CUREO_0285 sppA; signal peptide peptidase protease IV K04773 sppA; protease IV [EC:3.4.21.-]
D CUREO_1511 pepE; peptidase E K05995 pepE; dipeptidase E [EC:3.4.13.21]
D CUREO_0725 hslV; heat shock protein HslVU, ATP-dependent protease subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D CUREO_0374 collagenase-like peptidase, U32 family K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D CUREO_1381 hypothetical protein K08276 eco; ecotin
D CUREO_0613 alpha2-macroglobulin family protein K06894 yfhM; alpha-2-macroglobulin
C 01003 Glycosyltransferases [BR:cure01003]
D CUREO_0614 pbpC; penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D CUREO_0584 pbpA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D CUREO_1373 pglA; N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase K15914 pglA; N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase [EC:2.4.1.290]
D CUREO_1377 pglH; GalNAc-alpha-(1,4)-GalNAc-alpha-(1, 3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase K17249 pglH; GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase [EC:2.4.1.292]
D CUREO_1375 pglJ; N-acetylgalactosamine-N, N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase K17248 pglJ; N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.291]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:cure01005]
D CUREO_0083 lpxA; UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D CUREO_1474 lpxB; lipid A disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D CUREO_0271 lpxC; UDP-3-O-acyl-N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D CUREO_0871 lpxD; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D CUREO_1471 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D CUREO_1007 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D CUREO_1093 waaM; lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D CUREO_0379 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D CUREO_1353 kdsA; 3-deoxy-D-manno-octulosonate 8-phosphate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D CUREO_1012 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D CUREO_0927 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]
D CUREO_0050 kpsF; D-arabinose 5-phosphate isomerase K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D CUREO_1092 waaC; heptosyltransferase I K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D CUREO_1104 waaF; heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D CUREO_1103 glycosyltransferase, family 1 K02844 waaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]
D CUREO_1102 O-antigen ligase family protein K02847 waaL; O-antigen ligase [EC:2.4.99.26]
D CUREO_1095 waaQ; heptosyltransferase III K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]
D CUREO_1105 gmhA; sedoheptulose 7-phosphate isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D CUREO_1108 gmhB; D,D-heptose 1,7-bisphosphate phosphatase K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D CUREO_1106 waaE; D,D-heptose 1-phosphate adenosyltransferase / 7-phosphate kinase K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]
D CUREO_1107 waaD; ADP-L-glycero-D-mannoheptose-6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D CUREO_0717 glycosyltransferase, family 2 K20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:cure01011]
D CUREO_0624 murA; UDP-N-acetylglucosamine enolpyruvoyl transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D CUREO_0201 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D CUREO_0309 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D CUREO_1551 murD; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D CUREO_0139 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D CUREO_0884 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D CUREO_1209 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D CUREO_1552 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D CUREO_0739 murG; N-acetylglucosaminyl transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D CUREO_1327 bacA; undecaprenyl pyrophosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D CUREO_0890 murein biosynthesis integral membrane protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D CUREO_0584 pbpA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D CUREO_0614 pbpC; penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D CUREO_0921 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D CUREO_0590 ftsI; cell division protein FtsI / penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D CUREO_0670 slt; soluble lytic murein transglycosylase K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D CUREO_0930 lytic transglycosylase K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]
D CUREO_0775 YceG-like protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
D CUREO_0929 rlpA; rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D CUREO_0941 amiA; N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:cure01004]
D CUREO_0551 fabD; malonyl-CoA-[acp] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D CUREO_0162 fabH; beta-ketoacyl-[acp] synthase III (KASIII) K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D CUREO_0165 fabF; beta-ketoacyl-[acp] synthase II (KASII) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D CUREO_0163 fabG; 3-oxo-acyl-[acp] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D CUREO_0082 fabZ; 3-hydroxyacyl-[acp] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D CUREO_1385 fabI; enoyl-[acp] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D CUREO_1434 acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
D CUREO_0161 plsX; acyl phosphate synthase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D CUREO_1425 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D CUREO_0450 plsC; 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins [BR:cure01008]
D CUREO_0914 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01006 Prenyltransferases [BR:cure01006]
D CUREO_0142 ispA; geranyl diphosphate synthase / farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D CUREO_0640 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D CUREO_0697 ispU; undecaprenyl diphosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D CUREO_1600 miaA; tRNA(i6A37) synthase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D CUREO_1640 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
C 01007 Amino acid related enzymes [BR:cure01007]
D CUREO_0231 gltX2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CUREO_0668 gltX1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D CUREO_0943 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CUREO_1358 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D CUREO_0891 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D CUREO_1303 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CUREO_0675 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D CUREO_0299 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D CUREO_0612 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D CUREO_0424 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CUREO_1401 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D CUREO_0934 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CUREO_0618 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0495 hisZ; ATP phosphoribosyltransferase HisG(S)Z, hetero-octameric short form, regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0376 glyQ; glycyl-tRNA synthetase, alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D CUREO_1030 glyS; glycyl-tRNA synthetase, beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D CUREO_1361 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D CUREO_0642 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D CUREO_1523 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D CUREO_0587 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D CUREO_0358 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D CUREO_0359 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D CUREO_0615 aspB; aspartate aminotransferase, aminotransferase, classes I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D CUREO_1652 aspartate aminotransferase K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-]
D CUREO_1462 hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D CUREO_1023 argD; N-succinyldiaminopimelate-aminotransferase / acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D CUREO_0369 bioAD; bifunctional 7,8-diaminopelargonic acid synthase / dethiobiotin synthetase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D CUREO_1183 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D CUREO_1075 D-amino acid aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D CUREO_0079 ilvE; branched-chain amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D CUREO_1456 serC; phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:cure00194]
D CUREO_0543 atpC; ATP synthase, F1 complex, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D CUREO_0542 atpD; ATP synthase, F1 complex, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D CUREO_0541 atpG; ATP synthase, F1 complex, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D CUREO_0540 atpA; ATP synthase, F1 complex, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D CUREO_0539 atpH; ATP synthase, F1 complex, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D CUREO_0537 atpF'; ATP synthase, F0 complex, b' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D CUREO_0538 atpF; ATP synthase, F0 complex, b subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D CUREO_0354 atpE; ATP synthase, F0 complex, c subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D CUREO_1017 atpB; ATP synthase, F0 complex, a subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:cure03000]
D CUREO_0203 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1163 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_0371 transcriptional regulator, MocR family K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D CUREO_1491 cmeR; multidrug efflux system CmeABC transcriptional regulator, TetR family K18992 cmeR; TetR/AcrR family transcriptional regulator, cmeABC operon repressor
D CUREO_1071 hspR; heat shock transcriptional regulator, MerR family K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D CUREO_0401 transcriptional regulator, Fur family K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D CUREO_1400 fur; ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D CUREO_1460 perR; peroxide stress transcriptional regulator PerR K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D CUREO_0797 transcriptional regulator, BadM/Rrf2 family K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
D CUREO_1064 putative transcriptional regulator K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor
D CUREO_0845 arsR; transcriptional regulator, ArsR family K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D CUREO_0417 transcriptional regulator, ArsR family K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D CUREO_0534 birA; biotin-[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D CUREO_0190 molybdenum-pterin-binding domain protein K02019 modE; molybdate transport system regulatory protein
D CUREO_0475 transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein
D CUREO_0748 nikR; nickel responsive regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D CUREO_1345 toxin-antitoxin system, antitoxin component K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D CUREO_0536 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D CUREO_0655 hrcA; heat-inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor
D CUREO_0557 dksA; DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
C 03021 Transcription machinery [BR:cure03021]
D CUREO_0135 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D CUREO_1277 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D CUREO_1276 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D CUREO_0945 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D CUREO_1044 rpoD; RNA polymerase sigma70 factor K03086 rpoD; RNA polymerase primary sigma factor
D CUREO_0181 nusA; transcription termination factor K02600 nusA; transcription termination/antitermination protein NusA
D CUREO_1349 nusB; transcription antitermination protein K03625 nusB; transcription antitermination protein NusB
D CUREO_1282 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D CUREO_0557 dksA; DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D CUREO_1473 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D CUREO_0171 rho; transcription termination factor K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:cure03019]
D CUREO_1508 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D CUREO_0048 mRNA degradation ribonuclease J1/J2 (metallo-beta-lactamase superfamily) K12574 rnj; ribonuclease J [EC:3.1.-.-]
D CUREO_1142 ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-]
D CUREO_0828 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D CUREO_0057 ATP-dependent DNA helicase (RecQ/UvrD domains) K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D CUREO_0345 pnp; polynucleotide phosphorylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D CUREO_0171 rho; transcription termination factor K03628 rho; transcription termination factor Rho
D CUREO_0657 dnaK; chaperone and heat shock protein 70 K04043 dnaK; molecular chaperone DnaK
D CUREO_0768 groEL; 60 kD chaperonin (cpn60) K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CUREO_1172 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D CUREO_0577 ppk2; polyphosphate kinase 2 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
D CUREO_0808 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:cure03011]
D CUREO_0362 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D CUREO_1309 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D CUREO_0115 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D CUREO_0134 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D CUREO_0126 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D CUREO_0830 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D CUREO_1272 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D CUREO_0123 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D CUREO_0511 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D CUREO_0108 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D CUREO_0133 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D CUREO_1273 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D CUREO_0132 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D CUREO_0122 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D CUREO_0798 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D CUREO_0382 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D CUREO_0118 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D CUREO_0832 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D CUREO_0113 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D CUREO_0069 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D CUREO_1489 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D CUREO_1280 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D CUREO_0112 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D CUREO_0109 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D CUREO_0110 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D CUREO_0121 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D CUREO_0124 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D CUREO_0724 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D CUREO_1279 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D CUREO_1281 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D CUREO_1278 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D CUREO_0510 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D CUREO_0119 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D CUREO_0127 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D CUREO_0116 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D CUREO_0136 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D CUREO_0125 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D CUREO_0386 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D CUREO_0075 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D CUREO_0529 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D CUREO_0114 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D CUREO_0111 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D CUREO_0120 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D CUREO_0530 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D CUREO_1206 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D CUREO_0117 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D CUREO_1647 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D CUREO_0160 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D CUREO_1285 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D CUREO_1114 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D CUREO_0076 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D CUREO_0131 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D CUREO_1467 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D CUREO_0489 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_0635 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_1556 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_0485 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_1560 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0631 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0488 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_1557 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_0634 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:cure03009]
D CUREO_1508 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D CUREO_0727 era; GTP-binding protein K03595 era; GTPase
D CUREO_0531 obgE; GTPase ObgE K03979 obgE; GTPase [EC:3.6.5.-]
D CUREO_0557 dksA; DnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D CUREO_0181 nusA; transcription termination factor K02600 nusA; transcription termination/antitermination protein NusA
D CUREO_1349 nusB; transcription antitermination protein K03625 nusB; transcription antitermination protein NusB
D CUREO_1282 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D CUREO_0047 rsmA; 16S rRNA m62A1518,m62A1519 dimethyltransferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D CUREO_1646 rsmE; 16S rRNA m3U1498 methyltransferase K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D CUREO_1298 gidB; 16S rRNA m7G527 methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D CUREO_1079 rsmH; 16S rRNA m4C1402 methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D CUREO_1648 tetrapyrrole methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D CUREO_0802 tlyA; pore-forming hemolysin K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D CUREO_1649 rRNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D CUREO_0556 SPOUT methyltransferase K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D CUREO_0044 rlmN; 23S rRNA m2A2503 methyltransferase / tRNA m2A37 methyltransferase K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D CUREO_0051 rluB; 23S rRNA pseudouridine 2605 synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D CUREO_0043 23S rRNA pseudouridine synthase, RluD family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D CUREO_0380 rluA; 23S rRNA and tRNA pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D CUREO_0952 rluD; 23S rRNA pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D CUREO_0252 acetyltransferase, RimI family K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D CUREO_0384 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM
D CUREO_1410 radical SAM methylthiotransferase, MiaB/RimO family K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D CUREO_1365 prmA; 50S ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D CUREO_0824 Holliday junction resolvase-like protein (UPF0081 domain) K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D CUREO_1356 engA; GTP-binding protein K03977 engA; GTPase
D CUREO_0944 spoT; ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D CUREO_0276 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D CUREO_0277 hypothetical protein K09748 rimP; ribosome maturation factor RimP
D CUREO_0662 metal-dependent hydrolase (UPF0054 domain protein) K07042 ybeY; probable rRNA maturation factor
D CUREO_1196 sigma-54 modulation protein/ribosomal protein S30EA family K05808 hpf; ribosome hibernation promoting factor
D CUREO_1191 ychF; GTP-binding protein, putative GTP-dependent translation factor K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:cure03016]
D CUREO_1034 cca; multifunctional tRNA nucleotidyl transferase / 2'3'-cyclic phosphodiesterase / 2' nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D CUREO_0231 gltX2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CUREO_0642 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D CUREO_0299 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D CUREO_0424 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CUREO_0675 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D CUREO_1303 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CUREO_1401 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D CUREO_0934 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CUREO_0587 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D CUREO_1523 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D CUREO_1361 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D CUREO_0891 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D CUREO_0612 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D CUREO_0618 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0495 hisZ; ATP phosphoribosyltransferase HisG(S)Z, hetero-octameric short form, regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CUREO_0358 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D CUREO_0359 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D CUREO_0943 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CUREO_1358 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D CUREO_0357 PKCI-related HIT family hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D CUREO_0950 trmI; tRNA m7G46 methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D CUREO_0694 truA; tRNA pseudouridine synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D CUREO_0602 truB; tRNA pseudouridine 55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D CUREO_0993 truD; tRNA pseudouridine 13 synthase K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D CUREO_1568 iscS; cysteine desulfurase/aminotransferase (IscS/NifS) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CUREO_1600 miaA; tRNA(i6A37) synthase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D CUREO_1109 mnmE; 5-carboxymethylaminomethyluridine-tRNA synthase MnmEG, GTPase component K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D CUREO_1313 mnmG; 5-carboxymethylaminomethyluridine-tRNA synthase MnmEG, MnmG component K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D CUREO_0477 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D CUREO_0205 cysQ; adenosine-3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D CUREO_1113 rnpA; ribonuclease P, protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D CUREO_0991 ribonuclease P, RNA component K01978 rnpB; M1 RNA
D CUREO_0376 glyQ; glycyl-tRNA synthetase, alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D CUREO_1030 glyS; glycyl-tRNA synthetase, beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D CUREO_0668 gltX1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D CUREO_0559 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D CUREO_0179 miaB; isopentenyl-adenosine A37 tRNA methylthiolase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D CUREO_0799 cmoA; carboxy-S-adenosyl-L-methionine synthase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D CUREO_1161 cmoB; tRNA (cmo5U34)-carboxymethyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D CUREO_0856 trmA; tRNA m5U54 methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D CUREO_0385 trmD; tRNA m1G37 methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D CUREO_1032 rRNA methylase, SpoU family K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D CUREO_0989 tRNA m6A37 methyltransferase TrmN6 K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
D CUREO_0291 mnmA; tRNA U34 2-thiouridylase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D CUREO_1504 putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D CUREO_0553 adenine nucleotide alpha hydrolase, possible tRNA 2-thiocytidine biosynthesis protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D CUREO_0940 mnmC; bifunctional 5-methylaminomethyl-2-thiouridine-forming methyltransferase / FAD-dependent demodification enzyme K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D CUREO_0812 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D CUREO_0663 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D CUREO_1644 queD; 6-carboxy-5,6,7,8-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D CUREO_1643 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D CUREO_0005 queF; 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D CUREO_0081 hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D CUREO_0765 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D CUREO_1411 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D CUREO_0272 tRNA A37 threonylcarbamoyladenosine modification protein TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D CUREO_0155 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D CUREO_0721 hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D CUREO_1583 dinucleotide-utilizing enzyme, molybdopterin/thiamine biosynthesis family 1 K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
D CUREO_0828 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D CUREO_0345 pnp; polynucleotide phosphorylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:cure03012]
D CUREO_0275 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D CUREO_1522 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D CUREO_1308 tsf; translation elongation factor EF-Ts K02357 tsf; elongation factor Ts
D CUREO_1286 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D CUREO_1271 fusA; translation elongation factor EF-G K02355 fusA; elongation factor G
D CUREO_0239 selB; selenocysteine-specific elongation factor K03833 selB; selenocysteine-specific elongation factor
D CUREO_0068 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D CUREO_1454 frr; ribosome releasing factor K02838 frr; ribosome recycling factor
D CUREO_1119 hemK; protein-(glutamine-N5) methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D CUREO_1466 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D CUREO_0130 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D CUREO_1337 efp; translation elongation factor EF-P K02356 efp; elongation factor P
D CUREO_1407 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:cure03110]
D CUREO_0597 clpA; ATP-dependent Clp protease, ATP-binding subunit K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
D CUREO_0904 clpB; ATP-dependent Clp protease, ATP-binding subunit K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D CUREO_0084 clpX; ATP-dependent ClpXP protease, ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D CUREO_0726 hslU; heat shock protein HslVU, ATPase subunit K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D CUREO_0657 dnaK; chaperone and heat shock protein 70 K04043 dnaK; molecular chaperone DnaK
D CUREO_0768 groEL; 60 kD chaperonin (cpn60) K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CUREO_0325 dnaJ; co-chaperone and heat shock protein K03686 dnaJ; molecular chaperone DnaJ
D CUREO_1072 cbpA; co-chaperone-curved DNA binding protein A K05516 cbpA; curved DNA-binding protein
D CUREO_1085 Dna-J like membrane chaperone protein K05801 djlA; DnaJ like chaperone protein
D CUREO_0656 grpE; heat shock protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE
D CUREO_1317 heat-shock protein Hsp20 K13993 HSP20; HSP20 family protein
D CUREO_0767 groES; 10 kD chaperonin (cpn10) K04078 groES; chaperonin GroES
D CUREO_1364 ftsH2; integral membrane ATP-dependent zinc metallopeptidase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D CUREO_0760 ftsH1; integral membrane ATP-dependent zinc metallopeptidase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D CUREO_1017 atpB; ATP synthase, F0 complex, a subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D CUREO_0795 hypA; hydrogenase nickel insertion protein HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D CUREO_0790 hypB; hydrogenase nickel insertion protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D CUREO_0865 ppiB; peptidyl-prolyl cis-trans isomerase B K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D CUREO_1081 putative periplasmic folding chaperone K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
D CUREO_0550 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D CUREO_1157 peb4; SurA-like chaperone / peptidyl-prolyl cis-trans isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D CUREO_1655 trx; thioredoxin K03671 TXN; thioredoxin
D CUREO_1338 protein-disulfide isomerase K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D CUREO_0238 putative thioredoxin-like protein, DsbA family K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D CUREO_0578 dsbD; thiol:disulfide interchange protein DsbD K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]
C 04131 Membrane trafficking [BR:cure04131]
D CUREO_0158 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D CUREO_1449 SPFH domain-containing protein K07192 FLOT; flotillin
D CUREO_1388 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CUREO_0321 pykF; pyruvate kinase I K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D CUREO_1029 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
C 04121 Ubiquitin system
C 03051 Proteasome [BR:cure03051]
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 03032 DNA replication proteins [BR:cure03032]
D CUREO_1507 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D CUREO_0203 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1163 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_0740 putative helicase, PIF1 family (DUF889 domain) K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D CUREO_0753 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D CUREO_0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D CUREO_0834 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D CUREO_1505 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1333 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D CUREO_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D CUREO_0829 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D CUREO_0805 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D CUREO_1208 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D CUREO_0173 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D CUREO_0106 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D CUREO_0970 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D CUREO_0003 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D CUREO_0208 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D CUREO_1629 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:cure03036]
D CUREO_0203 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1163 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1508 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D CUREO_1449 SPFH domain-containing protein K07192 FLOT; flotillin
D CUREO_0753 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D CUREO_1072 cbpA; co-chaperone-curved DNA binding protein A K05516 cbpA; curved DNA-binding protein
D CUREO_0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D CUREO_1148 DNA-binding ferritin-like protein K04047 dps; starvation-inducible DNA-binding protein
D CUREO_1082 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D CUREO_0949 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D CUREO_0590 ftsI; cell division protein FtsI / penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D CUREO_0737 ftsK; DNA segregation ATPase FtsK/SpoIIIE K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D CUREO_0738 ftsW; cell division protein, FtsW/RodA/SpoVE family K03588 ftsW; cell division protein FtsW
D CUREO_0948 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D CUREO_1083 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D CUREO_0941 amiA; N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D CUREO_1492 cmeA; multidrug efflux system CmeABC, periplasmic fusion protein CmeA K03585 acrA; membrane fusion protein, multidrug efflux system
D CUREO_0085 mrdB; cell wall shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D CUREO_0086 mreC; rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D CUREO_0953 rodA; rod shape-determining protein K05837 rodA; rod shape determining protein RodA
D CUREO_0535 parA; chromosome partitioning protein K03496 parA; chromosome partitioning protein
D CUREO_1637 partitioning protein ParA K03496 parA; chromosome partitioning protein
D CUREO_0536 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D CUREO_1313 mnmG; 5-carboxymethylaminomethyluridine-tRNA synthase MnmEG, MnmG component K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D CUREO_1298 gidB; 16S rRNA m7G527 methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D CUREO_0773 xerH; integrase/recombinase K04763 xerD; integrase/recombinase XerD
D CUREO_0568 mrp; ATP/GTP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D CUREO_0817 Fic family protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D CUREO_0818 Fic family protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D CUREO_0924 engB; ribosome biogenesis GTP-binding protein YsxC/EngB K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:cure03400]
D CUREO_0860 ogt; O-6-alkylguanine-DNA/cysteine-protein-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CUREO_1483 ung; uracil-DNA glycosylase, family 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D CUREO_1158 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D CUREO_1118 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D CUREO_0265 xth; exodeoxyribonuclease III (exonuclease III) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D CUREO_1519 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D CUREO_0032 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D CUREO_0803 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D CUREO_0524 uvrA; UvrABC nucleotide excision repair complex, subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D CUREO_0560 uvrB; UvrABC nucleotide excision repair complex, subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D CUREO_0330 uvrC; UvrABC nucleotide excision repair complex, subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D CUREO_0603 UvrD/REP family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_0693 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D CUREO_1277 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D CUREO_1276 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D CUREO_0135 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D CUREO_0945 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D CUREO_0428 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D CUREO_0311 mutS2; DNA mismatch binding protein, MutS2 family K07456 mutS2; DNA mismatch repair protein MutS2
D CUREO_1457 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D CUREO_0303 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D CUREO_1333 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D CUREO_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D CUREO_0829 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D CUREO_0805 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D CUREO_1208 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D CUREO_0173 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0509 addA; exonuclease V, helicase AddA K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D CUREO_0199 recA; recombinase K03553 recA; recombination protein RecA
D CUREO_0885 ruvA; RuvABC resolvasome, subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D CUREO_0976 ruvB; RuvABC resolvasome, subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D CUREO_1673 ruvC; RuvABC resolvasome, subunit RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D CUREO_0664 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D CUREO_1146 radA; DNA repair and recombination protein K04485 radA; DNA repair protein RadA/Sms
D CUREO_1174 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D CUREO_0322 recR; recombination protein K06187 recR; recombination protein RecR
D CUREO_0932 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CUREO_0508 addB; exonuclease V, helicase AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D CUREO_0970 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D CUREO_0003 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D CUREO_0208 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D CUREO_1629 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D CUREO_0753 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D CUREO_0057 ATP-dependent DNA helicase (RecQ/UvrD domains) K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D CUREO_0983 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D CUREO_1255 DNA-damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D CUREO_0041 nrdA; aerobic ribonucleoside-diphosphate reductase Ia, B1 protein subunit NrdA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CUREO_0035 nrdB; aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:cure03029]
D CUREO_1315 petB; ubiquinol cytochrome c oxidoreductase PetABC, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D CUREO_0275 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D CUREO_1522 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D CUREO_1308 tsf; translation elongation factor EF-Ts K02357 tsf; elongation factor Ts
D CUREO_1286 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D CUREO_1271 fusA; translation elongation factor EF-G K02355 fusA; elongation factor G
D CUREO_0727 era; GTP-binding protein K03595 era; GTPase
D CUREO_0943 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CUREO_0424 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CUREO_0934 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CUREO_1303 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CUREO_0300 gatA; Glu-tRNA(Gln) amidotransferase, subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D CUREO_1016 gatB; Glu-tRNA(Gln) amidotransferase, subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D CUREO_1397 gatC; Glu-tRNA(Gln) amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D CUREO_0740 putative helicase, PIF1 family (DUF889 domain) K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D CUREO_1266 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_1632 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0831 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D CUREO_0268 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family
D CUREO_0657 dnaK; chaperone and heat shock protein 70 K04043 dnaK; molecular chaperone DnaK
D CUREO_0656 grpE; heat shock protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE
D CUREO_0768 groEL; 60 kD chaperonin (cpn60) K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CUREO_0767 groES; 10 kD chaperonin (cpn10) K04078 groES; chaperonin GroES
D CUREO_0325 dnaJ; co-chaperone and heat shock protein K03686 dnaJ; molecular chaperone DnaJ
D CUREO_1568 iscS; cysteine desulfurase/aminotransferase (IscS/NifS) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CUREO_0568 mrp; ATP/GTP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D CUREO_1111 oxaA; 60 kDa inner-membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:cure02000]
D CUREO_0338 ABC transporter, ATP-binding protein/permease K14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA/YbtP [EC:7.-.-.-]
D CUREO_0337 ABC transporter, ATP-binding protein/permease K14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB/YbtQ [EC:7.-.-.-]
D CUREO_0892 msbA; lipid A export ATP-binding/permease protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D CUREO_1544 type I secretion system, ABC transporter, HlyB family K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D CUREO_0707 macB; macrolide-specific efflux protein, ATP-binding/permease protein MacB K05685 macB; macrolide transport system ATP-binding/permease protein [EC:7.6.2.-]
D CUREO_0217 ABC transporter, ATP-binding/permease protein K06159 yojI; multidrug/microcin transport system ATP-binding/permease protein
D CUREO_1123 ABC transporter, ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein
D CUREO_0191 modA; molybdenum ABC transporter ModABC, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D CUREO_0193 modB; molybdenum ABC transporter ModABC, permease protein K02018 modB; molybdate transport system permease protein
D CUREO_0194 modC; molybdenum ABC transporter ModABC, ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D CUREO_0583 tupA; tungsten ABC transporter TupABC, periplasmic tungstate-binding protein K05772 tupA; tungstate transport system substrate-binding protein
D CUREO_0582 tupB; tungsten ABC transporter TupABC, permease protein K05773 tupB; tungstate transport system permease protein
D CUREO_0581 tupC; tungsten ABC transporter TupABC, ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D CUREO_0648 iron ABC transporter, periplasmic iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D CUREO_0649 iron ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D CUREO_0650 iron ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D CUREO_0887 lipid asymmetry ABC-type transporter Mla, periplasmic component MlaD K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D CUREO_0889 lipid asymmetry ABC-type transporter Mla, permease component MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D CUREO_0888 lipid asymmetry ABC-type transporter Mla, ATPase component MlaF K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D CUREO_0886 hypothetical protein K18480 linN; cholesterol transport system auxiliary component
D CUREO_1124 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_1129 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D CUREO_1128 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D CUREO_1127 pstA; phosphate ABC transporter, permease protein K02038 pstA; phosphate transport system permease protein
D CUREO_1126 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D CUREO_1325 amino acid ABC transporter, periplasmic substrate-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D CUREO_1322 amino acid ABC transporter, permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein
D CUREO_1323 amino acid ABC transporter, ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D CUREO_0679 metQ; DL-methionine ABC transporter MetINQ, substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein
D CUREO_0607 metI; DL-methionine ABC transporter MetINQ, permease protein K02072 metI; D-methionine transport system permease protein
D CUREO_0608 metN; DL-methionine ABC transporter MetINQ, ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein
D CUREO_0678 amino acid ABC transporter, periplasmic substrate-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_0055 ABC transporter, periplasmic substrate-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_0435 cjaA; amino acid ABC transporter, periplasmic cysteine-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_1324 amino acid ABC transporter, periplasmic substrate-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_0326 periplasmic substrate-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_0861 amino acid ABC transporter, periplasmic substrate-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D CUREO_0446 amino acid ABC transporter, permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D CUREO_0447 papP; pathogenesis-associated glutamine ABC transporter, permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D CUREO_0444 papQ; pathogenesis-associated glutamine ABC transporter, ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D CUREO_0443 dipeptide/oligopeptide/nickel ABC transporter, periplasmic substrate-binding protein K25103 nikZ; nickel transport system substrate-binding protein
D CUREO_0442 dipeptide/oligopeptide/nickel ABC transporter, permease protein K25104 nikY; nickel transport system permease protein
D CUREO_0441 dipeptide/oligopeptide/nickel ABC transporter, permease protein K25105 nikX; nickel transport system permease protein
D CUREO_0440 dipeptide/oligopeptide/nickel ABC transporter, ATP-binding protein K25106 nikW; nickel transport system ATP-binding protein [EC:7.2.2.11]
D CUREO_0439 dipeptide/oligopeptide/nickel ABC transporter, ATP-binding protein K25107 nikV; nickel transport system ATP-binding protein [EC:7.2.2.11]
D CUREO_0224 chuD; heme ABC transporter ChuBCD, periplasmic substrate-binding protein K25034 btuF; cobalamin transport system substrate-binding protein
D CUREO_0222 chuB; heme ABC transporter ChuBCD, permease protein K25027 btuC; cobalamin transport system permease protein
D CUREO_0223 chuC; heme ABC transporter ChuBCD, ATP-binding protein K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D CUREO_0060 znuA; zinc ABC transporter ZnuABC, periplasmic zinc-binding protein K09815 znuA; zinc transport system substrate-binding protein
D CUREO_0063 znuB; zinc ABC transporter ZnuABC, membrane protein K09816 znuB; zinc transport system permease protein
D CUREO_0062 znuC; zinc ABC transporter ZnuABC, ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D CUREO_0400 hypothetical protein K10094 cbiK; nickel transport protein
D CUREO_0695 putative lipooligosaccharide transport system, permease component (LptF family) K07091 lptF; lipopolysaccharide export system permease protein
D CUREO_1465 putative lipooligosaccharide transport system, permease component (LptG family) K11720 lptG; lipopolysaccharide export system permease protein
D CUREO_0720 putative lipooligosaccharide transport system, ATP-binding component (LptB family) K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D CUREO_0869 multidrug ABC transporter, permease protein K25180 ybhR; drug efflux transport system permease protein
D CUREO_0868 multidrug ABC transporter, permease protein K25181 ybhS; drug efflux transport system permease protein
D CUREO_0867 multidrug ABC transporter, ATP-binding protein K25182 ybhF; drug efflux transport system ATP-binding protein
D CUREO_0866 multidrug resistance efflux pump K25183 ybhG; membrane fusion protein YbhG
D CUREO_0948 ftsX; cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D CUREO_0949 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D CUREO_0100 ABC transporter, permease protein, FtsX/LolC family K02004 ABC.CD.P; putative ABC transport system permease protein
D CUREO_0259 ferrirhodotorulic acid ABC transporter, permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D CUREO_0260 ferrirhodotorulic acid ABC transporter, permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D CUREO_0751 lolC; lipoprotein releasing system, transmembrane protein, LolC/E family K02004 ABC.CD.P; putative ABC transport system permease protein
D CUREO_0101 ABC transporter, ATP-binding protein, LolD family K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D CUREO_0258 ferrirhodotorulic acid ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D CUREO_1307 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D CUREO_0318 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D CUREO_0282 sodium:sulfate symporter family protein K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D CUREO_0283 sodium:sulfate symporter family protein K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D CUREO_1133 MatE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D CUREO_1048 major facilitator superfamily transporter K08224 ynfM; MFS transporter, YNFM family, putative membrane transport protein
D CUREO_1205 putative potassium channel protein (TrkA domain) K10716 kch; voltage-gated potassium channel
D CUREO_0391 Von Willebrand factor type A (vWA) domain protein (BatA domain) K07114 yfbK; Ca-activated chloride channel homolog
D CUREO_0392 Von Willebrand factor type A (vWA) domain protein (BatA domain) K07114 yfbK; Ca-activated chloride channel homolog
D CUREO_0393 tetratricopeptide repeat domain protein K07114 yfbK; Ca-activated chloride channel homolog
D CUREO_1481 BAX inhibitor (BI)-1 like protein (UPF0005 domain) K19416 yccA; modulator of FtsH protease
D CUREO_1577 mscL; large conductance mechanosensitive channel protein K03282 mscL; large conductance mechanosensitive channel
D CUREO_1479 mscS; small conductance mechanosensitive channel protein K16052 ynaI; MscS family membrane protein
D CUREO_1165 Mg/Co/Ni transporter, MgtE family K06213 mgtE; magnesium transporter
D CUREO_1154 putative membrane protein (OmpA/MotB domain) K02557 motB; chemotaxis protein MotB
D CUREO_0214 exbB1; TonB system transport protein ExbB K03561 exbB; biopolymer transport protein ExbB
D CUREO_0219 exbB2; TonB system transport protein ExbB K03561 exbB; biopolymer transport protein ExbB
D CUREO_0463 exbB3; TonB system transport protein ExbB K03561 exbB; biopolymer transport protein ExbB
D CUREO_0215 exbD1; TonB system transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D CUREO_0220 exbD2; TonB system transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D CUREO_0462 exbD3; TonB system transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D CUREO_0545 tolR; Tol-Pal system subunit TolR K03559 exbD; biopolymer transport protein ExbD
D CUREO_0544 tolQ; Tol-Pal system subunit TolQ K03562 tolQ; biopolymer transport protein TolQ
D CUREO_0451 chromosome condensation protein CrcB K06199 crcB; fluoride exporter
D CUREO_0026 putative mercury transporter, membrane protein MerT K08363 merT; mercuric ion transport protein
D CUREO_0025 heavy metal-associated domain protein K08364 merP; periplasmic mercuric ion binding protein
D CUREO_0395 hypothetical membrane protein (DUF21 domain), possible TlyC family hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D CUREO_0150 hypothetical membrane protein (DUF21 domain), possible TlyC family hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D CUREO_0512 cadF; outer membrane fibronectin-binding protein K03286 TC.OOP; OmpA-OmpF porin, OOP family
D CUREO_0153 OmpA family protein K03286 TC.OOP; OmpA-OmpF porin, OOP family
D CUREO_0088 autotransporter domain protein K12516 bigA; putative surface-exposed virulence protein
D CUREO_0661 TonB-dependent receptor K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein
D CUREO_0210 TonB-dependent receptor K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein
D CUREO_0211 TonB-dependent heme/hemoglobin receptor K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein
D CUREO_0213 TonB-dependent heme/hemoglobin receptor K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein
D CUREO_0221 chuA; heme uptake system outer membrane receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D CUREO_1494 cmeC; multidrug efflux system CmeABC, outer membrane lipoprotein CmeC K18139 oprM; outer membrane protein, multidrug efflux system
D CUREO_0268 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family
D CUREO_1200 comL; DNA uptake lipoprotein K05807 bamD; outer membrane protein assembly factor BamD
D CUREO_0152 putative autotransporter adhesin (YadA domain) K21449 ata; trimeric autotransporter adhesin
D CUREO_1178 putative YadA-like adhesin K21449 ata; trimeric autotransporter adhesin
D CUREO_0925 putative lipooligosaccharide transport system, periplasmic component (LptA family) K09774 lptA; lipopolysaccharide export system protein LptA
D CUREO_0343 putative lipooligosaccharide transport system, OM component (LptD family) K04744 lptD; LPS-assembly protein
D CUREO_1139 cation diffusion facilitator family transporter K13283 fieF; ferrous-iron efflux pump FieF
D CUREO_1493 cmeB; multidrug efflux system CmeABC, inner membrane drug transporter CmeB K18138 acrB; multidrug efflux pump
D CUREO_0939 hypothetical protein K11741 sugE; quaternary ammonium compound-resistance protein SugE
D CUREO_1352 putative multidrug resistance protein, SMR family K18924 ykkC; paired small multidrug resistance pump
D CUREO_1351 putative multidrug resistance protein, SMR family K18925 ykkD; paired small multidrug resistance pump
D CUREO_0916 rarD1; resistance permease RarD K05786 rarD; chloramphenicol-sensitive protein RarD
D CUREO_0917 rarD2; resistance permease RarD K05786 rarD; chloramphenicol-sensitive protein RarD
D CUREO_1668 Na+/H+ antiporter family protein K07084 yuiF; putative amino acid transporter
D CUREO_1415 GntP family permease, putative gluconate transporter K03299 TC.GNTP; gluconate:H+ symporter, GntP family
D CUREO_0913 anaerobic C4-dicarboxylate transporter K07791 dcuA; anaerobic C4-dicarboxylate transporter DcuA
D CUREO_0479 dcuB; anaerobic C4-dicarboxylate transporter K07792 dcuB; anaerobic C4-dicarboxylate transporter DcuB
D CUREO_1088 BCCT (betaine/carnitine/choline) family transporter K02168 betT; choline/glycine/proline betaine transport protein
D CUREO_1320 sodium/proline symporter K11928 putP; sodium/proline symporter
D CUREO_0606 sstT; sodium ion-motive force-driven serine/threonine transporter K07862 sstT; serine/threonine transporter
D CUREO_0434 gltS; sodium:glutamate symporter K03312 gltS; glutamate:Na+ symporter, ESS family
D CUREO_1514 nhaA2; Na+/H+ antiporter K03313 nhaA; Na+:H+ antiporter, NhaA family
D CUREO_1408 nhaA1; Na+/H+ antiporter K03313 nhaA; Na+:H+ antiporter, NhaA family
D CUREO_1578 xanthine/uracil permease K02824 uraA; uracil permease
D CUREO_1050 xanthine/uracil/vitamin C permease K06901 pbuG; adenine/guanine/hypoxanthine permease
D CUREO_0844 acr3; arsenic resistance membrane transporter K03325 ACR3; arsenite transporter
D CUREO_1503 putative C4-dicarboxylate transporter, DcuC family K03326 TC.DCUC; C4-dicarboxylate transporter, DcuC family
D CUREO_1512 putative C4-dicarboxylate transporter, DcuC family K03326 TC.DCUC; C4-dicarboxylate transporter, DcuC family
D CUREO_0890 murein biosynthesis integral membrane protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D CUREO_1475 putative membrane protein, predicted permease K24180 mleP; malate permease and related proteins
D CUREO_1043 branched-chain amino acid transport protein, AzlC family K26605 azlC; branched chain amino acid efflux pump
D CUREO_1042 branched-chain amino acid transport protein, AzlD family K26606 azlD; branched chain amino acid efflux pump
D CUREO_0738 ftsW; cell division protein, FtsW/RodA/SpoVE family K03588 ftsW; cell division protein FtsW
D CUREO_0065 hypothetical membrane protein (DUF204 domain) K23242 mntP; manganese efflux pump family protein
D CUREO_0263 ferrirhodotorulic acid ABC transporter, inner membrane protein K07243 FTR; high-affinity iron transporter
D CUREO_0262 p19; ferrirhodotorulic acid ABC transporter, periplasmic binding protein K07230 p19; periplasmic iron binding protein
D CUREO_0061 putative nickel/cobalt ABC transporter, permease protein K08970 rcnA; nickel/cobalt transporter (NicO) family protein
D CUREO_0546 tolA; Tol-Pal system subunit TolA K03832 tonB; periplasmic protein TonB
D CUREO_0216 tonB1; energy transduction protein TonB K03832 tonB; periplasmic protein TonB
D CUREO_0461 tonB3; energy transduction protein TonB K03832 tonB; periplasmic protein TonB
D CUREO_0548 pal; Tol-Pal system peptidoglycan-associated lipoprotein K03640 pal; peptidoglycan-associated lipoprotein
D CUREO_0547 tolB; Tol-Pal system translocation protein TolB K03641 tolB; TolB protein
D CUREO_1658 molybdopterin-binding TMAO/DMSO reductase K07812 torZ; trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3]
D CUREO_1061 putative thiosulfate/polysulfide reductase, molybdenum-binding subunit K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D CUREO_1059 putative thiosulfate/polysulfide reductase, membrane-anchoring subunit K16294 psrC; polysulfide reductase chain C
D CUREO_1541 type I secretion system, membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D CUREO_1492 cmeA; multidrug efflux system CmeABC, periplasmic fusion protein CmeA K03585 acrA; membrane fusion protein, multidrug efflux system
D CUREO_0706 macA; macrolide-specific efflux protein, membrane fusion protein MacA K13888 macA; membrane fusion protein, macrolide-specific efflux system
D CUREO_0397 feoA; ferrous iron transport protein A K04758 feoA; ferrous iron transport protein A
D CUREO_0398 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D CUREO_0396 ABC-type long-chain fatty acid transport system, fused permease and ATPase components, SbmA family K17938 sbmA; peptide/bleomycin uptake transporter
C 02044 Secretion system [BR:cure02044]
D CUREO_1544 type I secretion system, ABC transporter, HlyB family K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D CUREO_1541 type I secretion system, membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D CUREO_0688 type II and III secretion system protein K02453 gspD; general secretion pathway protein D
D CUREO_0731 ctsD; transformation system, type II secretion system secretin protein CtsD K02453 gspD; general secretion pathway protein D
D CUREO_0736 ctsF; transformation system, type II secretion system membrane protein CtsF K02455 gspF; general secretion pathway protein F
D CUREO_0665 putative secretion system protein K02456 gspG; general secretion pathway protein G
D CUREO_0666 putative secretion system protein K02456 gspG; general secretion pathway protein G
D CUREO_0696 peptidase A24 N-terminal domain protein, putative prepilin signal peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D CUREO_1468 twitching motility protein K02669 pilT; twitching motility protein PilT
D CUREO_1398 twitching motility protein K02669 pilT; twitching motility protein PilT
D CUREO_0669 putative membrane protein, YGGT family K02221 yggT; YggT family protein
D CUREO_1555 competence protein ComEA helix-hairpin-helix repeat protein K02237 comEA; competence protein ComEA
D CUREO_1171 putative competence locus K02238 comEC; competence protein ComEC
D CUREO_0296 ctsW; transformation system, predicted amidophosphoribosyltransferase CtsW K02242 comFC; competence protein ComFC
D CUREO_1343 lytic transglycosylase K03194 virB1; type IV secretion system protein VirB1
D CUREO_1620 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D CUREO_1622 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D CUREO_1624 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D CUREO_1619 virB9; type IV secretion system protein VirB9 K12049 comB9; ComB9 competence protein
D CUREO_1618 virB8; type IV secretion system protein VirB8 K12050 comB8; ComB8 competence protein
D CUREO_1617 virB4; type IV secretion/conjugal transfer ATPase, VirB4 family K12053 comB4; ComB4 competence protein
D CUREO_1338 protein-disulfide isomerase K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D CUREO_0238 putative thioredoxin-like protein, DsbA family K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D CUREO_0088 autotransporter domain protein K12516 bigA; putative surface-exposed virulence protein
D CUREO_0750 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D CUREO_0421 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D CUREO_1283 secE; preprotein translocase SecYEG, SecE subunit K03073 secE; preprotein translocase subunit SecE
D CUREO_0422 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D CUREO_1455 secG; preprotein translocase SecYEG, SecG subunit K03075 secG; preprotein translocase subunit SecG
D CUREO_0128 secY; preprotein translocase SecYEG, SecY subunit K03076 secY; preprotein translocase subunit SecY
D CUREO_0381 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D CUREO_1145 ftsY; cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D CUREO_0420 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D CUREO_1111 oxaA; 60 kDa inner-membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CUREO_1304 putative twin arginine-targeting protein translocase, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D CUREO_0810 Sec-independent protein translocase protein K03117 tatB; sec-independent protein translocase protein TatB
D CUREO_0811 tatC; Sec-independent protein secretion pathway component K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:cure02042]
D CUREO_0687 zonular occludens toxin (Zot) family protein K10954 zot; zona occludens toxin
D CUREO_0395 hypothetical membrane protein (DUF21 domain), possible TlyC family hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D CUREO_0150 hypothetical membrane protein (DUF21 domain), possible TlyC family hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:cure02022]
D CUREO_1131 two-component system response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
D CUREO_1025 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1074 cprS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_0323 racS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1428 cosS; two-component system, sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1056 two-component system sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D CUREO_1427 cosR; two-component system, response regulator K02483 K02483; two-component system, OmpR family, response regulator
D CUREO_0324 racR; two-component system, response regulator K02483 K02483; two-component system, OmpR family, response regulator
D CUREO_1073 cprR; two-component system, response regulator K02483 K02483; two-component system, OmpR family, response regulator
D CUREO_0328 two-component system, sensor histidine kinase (NIT sensor domain) K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
D CUREO_0242 two-component system sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C 02035 Bacterial motility proteins [BR:cure02035]
D CUREO_1154 putative membrane protein (OmpA/MotB domain) K02557 motB; chemotaxis protein MotB
D CUREO_1468 twitching motility protein K02669 pilT; twitching motility protein PilT
D CUREO_1398 twitching motility protein K02669 pilT; twitching motility protein PilT
D CUREO_0696 peptidase A24 N-terminal domain protein, putative prepilin signal peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:cure04812]
D CUREO_0085 mrdB; cell wall shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D CUREO_1083 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D CUREO_1082 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D CUREO_0535 parA; chromosome partitioning protein K03496 parA; chromosome partitioning protein
D CUREO_1637 partitioning protein ParA K03496 parA; chromosome partitioning protein
D CUREO_0536 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:cure04147]
D CUREO_0910 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D CUREO_0198 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D CUREO_1388 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D CUREO_1387 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D CUREO_0321 pykF; pyruvate kinase I K00873 PK; pyruvate kinase [EC:2.7.1.40]
D CUREO_0156 ahpC; alkyl hydroperoxide reductase protein, peroxidase component K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D CUREO_1449 SPFH domain-containing protein K07192 FLOT; flotillin
D CUREO_0768 groEL; 60 kD chaperonin (cpn60) K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CUREO_0657 dnaK; chaperone and heat shock protein 70 K04043 dnaK; molecular chaperone DnaK
D CUREO_1149 pgi; phosphoglucose isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D CUREO_0301 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D CUREO_1286 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D CUREO_0357 PKCI-related HIT family hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D CUREO_0935 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D CUREO_1188 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D CUREO_0349 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D CUREO_0723 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D CUREO_0673 fbp; fructose-1,6-bisphosphatase I K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D CUREO_0370 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D CUREO_1296 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D CUREO_0103 phoA; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D CUREO_0363 serA; alpha-ketoglutarate reductase / D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D CUREO_1084 purH; AICAR transformylase / IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D CUREO_1386 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D CUREO_0801 outer membrane lipoprotein K03098 APOD; apolipoprotein D and lipocalin family protein
C 02048 Prokaryotic defense system [BR:cure02048]
D CUREO_0333 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D CUREO_1581 adenine-specific DNA methyltransferase (EcoRI methylase) K07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D CUREO_0203 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_1163 cytosine-specific DNA methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D CUREO_0033 putative restriction endonuclease K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]
D CUREO_0880 type II restriction endonuclease K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]
D CUREO_1346 toxin-antitoxin system, toxin component K06218 relE; mRNA interferase RelE/StbE
D CUREO_1345 toxin-antitoxin system, antitoxin component K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D CUREO_1083 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D CUREO_0085 mrdB; cell wall shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D CUREO_0231 gltX2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CUREO_1568 iscS; cysteine desulfurase/aminotransferase (IscS/NifS) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:cure01504]
D CUREO_1492 cmeA; multidrug efflux system CmeABC, periplasmic fusion protein CmeA K03585 acrA; membrane fusion protein, multidrug efflux system
D CUREO_1493 cmeB; multidrug efflux system CmeABC, inner membrane drug transporter CmeB K18138 acrB; multidrug efflux pump
D CUREO_1494 cmeC; multidrug efflux system CmeABC, outer membrane lipoprotein CmeC K18139 oprM; outer membrane protein, multidrug efflux system
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:cure00537]
D CUREO_0103 phoA; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:cure03100]
D CUREO_0486 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_0632 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1559 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1447 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D CUREO_1269 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_1497 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_0755 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_1498 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D CUREO_0956 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D CUREO_1341 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D CUREO_1444 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D CUREO_0692 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D CUREO_0579 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D CUREO_1339 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1067 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1521 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D CUREO_1446 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_0622 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_1288 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D CUREO_1496 tRNA-His K14226 tRNA-His; tRNA His
D CUREO_0487 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_1558 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_0633 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D CUREO_0355 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_0752 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1445 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1499 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D CUREO_1066 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D CUREO_1340 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D CUREO_1525 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_0691 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_1476 tRNA-Met K14230 tRNA-Met; tRNA Met
D CUREO_1550 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D CUREO_1495 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D CUREO_0145 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1347 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1442 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D CUREO_1287 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D CUREO_1290 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D CUREO_1284 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D CUREO_1289 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D CUREO_1342 tRNA-Val K14237 tRNA-Val; tRNA Val
D CUREO_1515 tRNA-Val K14237 tRNA-Val; tRNA Val
D CUREO_0485 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_1560 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0631 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D CUREO_0488 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_1557 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_0634 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D CUREO_0489 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_0635 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_1556 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D CUREO_0991 ribonuclease P, RNA component K01978 rnpB; M1 RNA
D CUREO_0974 10Sa RNA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D CUREO_1210 saccharopine dehydrogenase K27502 capadh; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55]
D CUREO_0099 msrAB; bifunctional (RS)-methionine sulfoxide reductase A/B K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]
D CUREO_0528 ccpA; periplasmic diheme cytochrome c peroxidase K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]
D CUREO_0080 bcp; thiol peroxidase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D CUREO_1452 tpx; lipid hydroperoxide peroxidase K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D CUREO_0785 hydB; [NiFe] hydrogenase, large subunit K05922 hydB; quinone-reactive Ni/Fe-hydrogenase large subunit [EC:1.12.5.1]
D CUREO_0784 hydA; [NiFe] hydrogenase, small subunit K05927 hydA; quinone-reactive Ni/Fe-hydrogenase small subunit [EC:1.12.5.1]
D CUREO_0963 FAD/FMN-containing dehydrogenase K24452 pinA; (+)-pinoresinol hydroxylase [EC:1.17.9.2]
D CUREO_0962 putative cytochrome c oxidase K24453 pinB; (+)-pinoresinol hydroxylase [EC:1.17.9.2]
D CUREO_0036 nrdG; anaerobic ribonucleoside triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D CUREO_0034 pcm; L-isoaspartate protein carboxylmethyltransferase, type II K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D CUREO_0226 putative coproporphyrinogen III oxidase K21936 chuW; anaerobilin synthase [EC:2.1.1.342]
D CUREO_1484 hemN3; oxygen-independent coproporphyrinogen III oxidase K23078 mqnK; menaquinone C8-methyltransferase [EC:2.1.1.350]
D CUREO_0419 lnt; apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D CUREO_0591 aat; leucyl, phenylalanyl-tRNA-protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
D CUREO_0758 ate; arginyltransferase K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29]
D CUREO_1374 pglB; undecaprenyl-diphosphooligosaccharide--protein glycotransferase K17251 pglB; undecaprenyl-diphosphooligosaccharide---protein glycotransferase [EC:2.4.99.19]
D CUREO_0981 lgt; phosphatidylglycerol-prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D CUREO_0189 opgB; phosphoglycerol transferase I K01002 mdoB; phosphoglycerol transferase [EC:2.7.8.20]
D CUREO_1372 pglC; N,N'-diacetylbacilliosaminyl-1-phosphate transferase K15915 pglC; undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase [EC:2.7.8.36]
D CUREO_0090 arylsulfate sulfotransferase K01023 assT; arylsulfate sulfotransferase [EC:2.8.2.22]
D CUREO_0092 arylsulfate sulfotransferase K01023 assT; arylsulfate sulfotransferase [EC:2.8.2.22]
D CUREO_0091 arylsulfate sulfotransferase K01023 assT; arylsulfate sulfotransferase [EC:2.8.2.22]
D CUREO_0704 hypothetical protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D CUREO_1116 acyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D CUREO_0628 sixA; phosphohistidine phosphatase K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D CUREO_0931 tatD; ssDNA/RNA exonuclease, 3' - 5' specific K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D CUREO_1572 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D CUREO_0314 endoribonuclease L-PSP family protein K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D CUREO_0388 MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D CUREO_1574 carbohydrate kinase, YjeF-related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D CUREO_1383 lig; DNA ligase K26441 lig; DNA ligase [EC:6.5.1.1]
D CUREO_0862 copA; copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D CUREO_0415 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D CUREO_0474 fdhD; formate dehydrogenase accessory protein K02379 fdhD; FdhD protein
D CUREO_1567 iscU; iron-sulfur cluster assembly scaffold protein IscU K13819 K13819; NifU-like protein
D CUREO_0741 napD; periplasmic nitrate reductase assembly protein K02570 napD; periplasmic nitrate reductase NapD
D CUREO_0743 napF; ferredoxin-type protein K02572 napF; ferredoxin-type protein NapF
D CUREO_0517 fldA; flavodoxin K03839 fldA; flavodoxin I
D CUREO_0746 napG; menaquinol dehydrogenase NapGH, periplasmic component NapG K02573 napG; ferredoxin-type protein NapG
D CUREO_0745 napH; menaquinol dehydrogenase NapGH, membrane component NapH K02574 napH; ferredoxin-type protein NapH
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D CUREO_0899 type III pyridoxal 5-phosphate (PLP)-dependent enzyme, YggS family K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D CUREO_0877 putative ubiquinone biosynthesis protein kinase K03688 ubiB; ubiquinone biosynthesis protein
D CUREO_0672 mobB; molybdenum cofactor guanylyltransferase protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
D CUREO_1275 DoxX family protein K15977 K15977; putative oxidoreductase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
C 99974 Translation
C 99975 Protein processing
D CUREO_0598 clpS; ATP-dependent Clp protease adaptor protein ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS
D CUREO_1570 tig; trigger factor (peptidyl-prolyl cis/trans isomerase, chaperone) K03545 tig; trigger factor
D CUREO_0017 ureE; urease accessory protein UreE K03187 ureE; urease accessory protein
D CUREO_0018 ureF; urease accessory protein UreF K03188 ureF; urease accessory protein
D CUREO_0019 ureG; urease accessory protein UreG K03189 ureG; urease accessory protein
D CUREO_0020 ureD; urease accessory protein UreD K03190 ureD; urease accessory protein
D CUREO_0600 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D CUREO_0791 hypC; hydrogenase assembly chaperone HypC K04653 hypC; hydrogenase expression/formation protein HypC
D CUREO_0792 hypD; hydrogenase expression/formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D CUREO_0794 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D CUREO_0789 hypF; [NiFe] hydrogenase maturation protein HypF K04656 hypF; hydrogenase maturation protein HypF
D CUREO_1573 Mg chelatase-related protein K07391 comM; magnesium chelatase family protein
C 99976 Replication and repair
D CUREO_1077 RmuC domain protein K09760 rmuC; DNA recombination protein RmuC
D CUREO_0432 magIII; 3-methyladenine DNA glycosylase K07457 K07457; endonuclease III related protein
D CUREO_1654 hypothetical protein K07460 yraN; putative endonuclease
D CUREO_0825 dprA; DNA processing chain A K04096 smf; DNA processing protein
D CUREO_1524 rarA; recombination factor protein RarA K07478 ycaJ; putative ATPase
D CUREO_1384 3'-5' exonuclease, PolB-like protein K07501 K07501; 3'-5' exonuclease
D CUREO_1601 site-specific recombinase, phage integrase family K14059 int; integrase
D CUREO_0187 site-specific recombinase, phage integrase family K14059 int; integrase
C 99979 Viral proteins
C 99998 Others
D CUREO_1247 putative restriction endonuclease K07504 K07504; predicted type IV restriction endonuclease
D CUREO_0141 YbaB/EbfC DNA-binding family protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D CUREO_0266 inorganic phosphate transporter, PitA family K03306 TC.PIT; inorganic phosphate transporter, PiT family
D CUREO_0368 sodium:solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D CUREO_0264 Na+-dependent transporter, SNF family K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D CUREO_1068 Na+-dependent transporter, SNF family (solute-binding domain) K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D CUREO_1069 Na+-dependent transporter, SNF family (solute-binding domain) K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D CUREO_1070 Na+-dependent transporter, SNF family (solute-binding domain) K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D CUREO_1438 brnQ; branched-chain amino acid transport system II carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family
D CUREO_1362 bile acid:sodium symporter K03453 TC.BASS; bile acid:Na+ symporter, BASS family
D CUREO_0483 sodium:sulfate symporter family protein K03319 TC.DASS; divalent anion:Na+ symporter, DASS family
C 99978 Cell growth
D CUREO_1110 putative RNA-binding protein (Jag domain) K06346 jag; spoIIIJ-associated protein
C 99993 Cell motility
C 99995 Signaling proteins
D CUREO_0008 typA; GTP-binding protein TypA K06207 typA; GTP-binding protein
C 99992 Structural proteins
D CUREO_0749 lolA; outer membrane lipoprotein carrier protein K03634 lolA; outer membrane lipoprotein carrier protein
D CUREO_0493 lipid asymmetry ABC-type transporter Mla, lipoprotein MlaA K04754 mlaA; phospholipid-binding lipoprotein MlaA
D CUREO_1211 putative autoinducer 2 transporter K11744 tqsA; AI-2 transport protein TqsA
C 99994 Others
D CUREO_1010 putative CutA1 divalent ion tolerance protein K03926 cutA; periplasmic divalent cation tolerance protein
D CUREO_0218 putative heme iron utilization protein, ChuX/HutX family K07227 chuX; heme iron utilization protein
D CUREO_1413 NosL family protein K19342 nosL; copper chaperone NosL
B
B 09194 Poorly characterized
C 99996 General function prediction only
D CUREO_1399 colicin V biosynthesis protein K03558 cvpA; membrane protein required for colicin V production
D CUREO_0961 putative acylesterase/phospholipase K07001 K07001; NTE family protein
D CUREO_1170 virulence factor, BrkB family protein K07058 K07058; membrane protein
D CUREO_0344 hypothetical protein K07100 K07100; putative phosphoribosyl transferase
D CUREO_0009 lemA; LemA protein K03744 lemA; LemA protein
D CUREO_0959 putative catabolite regulation protein K05805 creA; CreA protein
D CUREO_1403 hypothetical protein K03749 dedD; DedD protein
D CUREO_1370 PhnA domain-containing protein K06193 phnA; protein PhnA
C 99997 Function unknown
D CUREO_0098 hypothetical protein K06867 K06867; uncharacterized protein
D CUREO_0858 ankyrin repeat-containing protein K06867 K06867; uncharacterized protein
D CUREO_0951 fibronectin type III domain-containing protein K06882 K06882; uncharacterized protein
D CUREO_1330 hypothetical protein K06921 K06921; uncharacterized protein
D CUREO_0431 ATPase (AAA+ superfamily, DUF815 domain) K06923 K06923; uncharacterized protein
D CUREO_0988 hypothetical protein K06940 K06940; uncharacterized protein
D CUREO_0383 putative RNA-binding protein (KH domain) K06960 K06960; uncharacterized protein
D CUREO_0039 pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein K07005 K07005; uncharacterized protein
D CUREO_1666 putative neutral zinc metallopeptidase K07054 K07054; uncharacterized protein
D CUREO_1609 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D CUREO_1018 putative membrane protein, TauE/SafE family permease K07090 K07090; uncharacterized protein
D CUREO_0523 hypothetical protein K07090 K07090; uncharacterized protein
D CUREO_1328 sulfite exporter TauE/SafE K07090 K07090; uncharacterized protein
D CUREO_0796 DHH-type phosphohydrolase K07097 K07097; uncharacterized protein
D CUREO_0414 putative selenium metabolism protein, YedE family K07112 K07112; uncharacterized protein
D CUREO_0151 Sel1 domain repeat-containing protein K07126 K07126; uncharacterized protein
D CUREO_0610 Sel1 domain repeat-containing protein K07126 K07126; uncharacterized protein
D CUREO_0453 Sel1 domain repeat-containing protein K07126 K07126; uncharacterized protein
D CUREO_0975 Sel1 domain repeat-containing protein K07126 K07126; uncharacterized protein
D CUREO_0107 ATPase, AAA family protein K07133 K07133; uncharacterized protein
D CUREO_0378 zinc ribbon domain protein (DUF164 domain) K07164 K07164; uncharacterized protein
D CUREO_1112 hypothetical protein K08998 K08998; uncharacterized protein
D CUREO_0498 putative membrane protein K09792 K09792; uncharacterized protein
D CUREO_0023 SGNH family hydrolase K09795 K09795; uncharacterized protein
D CUREO_0826 divergent polysaccharide deacetylase K09798 K09798; uncharacterized protein
D CUREO_0104 hypothetical membrane protein (DUF475 domain) K09799 K09799; uncharacterized protein
D CUREO_0497 hypothetical protein K09804 K09804; uncharacterized protein
D CUREO_0049 hypothetical protein K09805 K09805; uncharacterized protein
D CUREO_0172 hypothetical protein K09807 K09807; uncharacterized protein
D CUREO_0754 hypothetical protein K09861 K09861; uncharacterized protein
D CUREO_0611 hypothetical protein K09922 K09922; uncharacterized protein
D CUREO_1359 hypothetical protein K09943 K09943; uncharacterized protein
D CUREO_1321 putative membrane protein K09943 K09943; uncharacterized protein
D CUREO_0764 hypothetical protein K09944 K09944; uncharacterized protein
D CUREO_1235 hypothetical protein K09960 K09960; uncharacterized protein
D CUREO_1237 hypothetical protein K09961 K09961; uncharacterized protein
D CUREO_1431 hypothetical protein K09979 K09979; uncharacterized protein
D CUREO_0253 hypothetical protein K01163 K01163; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 18, 2024