+F Repair protein KO
#
DNA Repair and Recombination Proteins - Crassostrea virginica (eastern oyster)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 111121007 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 111118907 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 111101457 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 111101679 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 111101938 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 111104284 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 111100499 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 111133661 uncharacterized protein LOC111133661 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 111114668 uncharacterized protein LOC111114668 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 111131615 cyclin-O-like K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 111128626 cyclin-O-like K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 111109690 uncharacterized protein LOC111109690 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 111120573 uncharacterized protein LOC111120573 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 111119714 uncharacterized protein LOC111119714 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 111118241 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 111123349 N-glycosylase/DNA lyase-like K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 111125609 N-glycosylase/DNA lyase-like K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 111127898 endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 111128622 endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 111115124 endonuclease 8-like 3 isoform X1 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 111099552 uncharacterized protein LOC111099552 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 111102061 uncharacterized protein LOC111102061 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 111108438 DNA-(apurinic or apyrimidinic site) lyase 2-like K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 111112959 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 111130346 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 111135402 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
F 111134440 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 111125562 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 111131043 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 111123176 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 111126184 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 111128010 DNA polymerase epsilon subunit 4-like K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 111120673 proliferating cell nuclear antigen-like isoform X1 K04802 PCNA; proliferating cell nuclear antigen
E 111137273 LOW QUALITY PROTEIN: flap endonuclease 1-like K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 111121171 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 111120810 DNA polymerase beta-like isoform X1 K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 111135198 DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
E 111135354 DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
E 111138126 DNA ligase 3-like K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 111128425 tyrosyl-DNA phosphodiesterase 1-like K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 111128516 tyrosyl-DNA phosphodiesterase 1-like K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 111136704 aprataxin-like isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 111137582 bifunctional polynucleotide phosphatase/kinase-like K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 111118490 uncharacterized protein F21D5.5-like K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 111125762 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 111126226 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 111135834 DNA polymerase lambda-like isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 111131837 poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 111127734 poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 111132307 uncharacterized protein LOC111132307 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 111135118 uncharacterized protein LOC111135118 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 111112939 poly [ADP-ribose] polymerase 3-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 111136562 poly [ADP-ribose] polymerase 2-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 111136597 poly [ADP-ribose] polymerase 2-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 111100311 poly [ADP-ribose] polymerase 4-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 111109822 DNA repair protein complementing XP-C cells homolog K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 111120048 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 111120079 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 111125421 LOW QUALITY PROTEIN: caltractin-like K10840 CETN2; centrin-2
F 111136013 LOW QUALITY PROTEIN: caltractin-like K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 111125628 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 111125715 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 111135325 cullin-4A-like K10609 CUL4; cullin 4
F 111129824 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 111133797 DNA damage-binding protein 2-like isoform X1 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 111102132 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 111135723 DNA-directed RNA polymerase II subunit RPB2-like K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 111136987 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 111136991 DNA-directed RNA polymerase II subunit RPB2-like isoform X1 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 111133143 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB3-like K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 111129570 DNA-directed RNA polymerase II subunit RPB3-like K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 111132777 DNA-directed RNA polymerase II subunit RPB4-like K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 111102974 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 111103988 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 111103789 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 111130689 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 111130698 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 111124019 DNA-directed RNA polymerases I, II, and III subunit RPABC3-like K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 111129014 DNA-directed RNA polymerase II subunit RPB9-like K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 111134430 DNA-directed RNA polymerase II subunit RPB11-a-like K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F 111125628 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 111125715 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 111135325 cullin-4A-like K10609 CUL4; cullin 4
F 111129824 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 111120860 DNA excision repair protein ERCC-8-like K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 111121400 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
F 111135591 UV-stimulated scaffold protein A-like K23720 UVSSA; UV-stimulated scaffold protein A
F 111118595 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 111104805 TFIIH basal transcription factor complex helicase XPB subunit-like K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 111101884 TFIIH basal transcription factor complex helicase XPB subunit-like isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 111131097 LOW QUALITY PROTEIN: TFIIH basal transcription factor complex helicase XPD subunit-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 111131487 TFIIH basal transcription factor complex helicase XPD subunit-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 111134971 general transcription factor IIH subunit 1-like K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 111132915 general transcription factor IIH subunit 2-like K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 111127293 general transcription factor IIH subunit 4-like K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 111125401 cyclin-dependent kinase 7-like isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 111111048 cyclin-H-like K06634 CCNH; cyclin H
E 111114853 cyclin-H-like isoform X1 K06634 CCNH; cyclin H
E 111128470 CDK-activating kinase assembly factor MAT1-like K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 111134654 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 111120888 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 111126776 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 111113135 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 111114574 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 111107427 DNA excision repair protein ERCC-1-like isoform X1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 111108639 DNA excision repair protein ERCC-1-like isoform X1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 111121059 LOW QUALITY PROTEIN: DNA repair endonuclease XPF-like K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 111121171 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 111135654 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 111135655 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 111135656 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 111135657 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 111135851 cullin-3-B-like K03869 CUL3; cullin 3
E 111103787 cullin-5-like K10612 CUL5; cullin 5
E 111121924 elongin-C K03872 ELOC; elongin-C
E 111122260 elongin-C K03872 ELOC; elongin-C
E 111132184 elongin-B-like K03873 ELOB; elongin-B
E 111131763 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 111137452 DNA mismatch repair protein Msh2-like K08735 MSH2; DNA mismatch repair protein MSH2
E 111131788 DNA mismatch repair protein Msh3-like K08736 MSH3; DNA mismatch repair protein MSH3
E 111127942 DNA mismatch repair protein Msh3-like K08736 MSH3; DNA mismatch repair protein MSH3
E 111110235 LOW QUALITY PROTEIN: DNA mismatch repair protein Msh6-like K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 111113121 PMS1 protein homolog 1-like K10864 PMS1; DNA mismatch repair protein PMS1
E 111112943 DNA mismatch repair protein Mlh1-like K08734 MLH1; DNA mismatch repair protein MLH1
E 111114242 DNA mismatch repair protein Mlh1-like K08734 MLH1; DNA mismatch repair protein MLH1
E 111118905 mismatch repair endonuclease PMS2-like K10858 PMS2; DNA mismatch repair protein PMS2
E 111119232 mismatch repair endonuclease PMS2-like isoform X1 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 111112959 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 111130346 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 111135402 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E 111134440 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 111134654 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 111120888 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 111126776 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 111131355 replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 111108767 replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 111132381 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 111134900 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 111135799 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 111122897 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
E 111137687 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 111120673 proliferating cell nuclear antigen-like isoform X1 K04802 PCNA; proliferating cell nuclear antigen
E 111128151 exonuclease 1-like K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 111125762 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 111126226 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 111121171 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 111119066 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 111120092 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 111127260 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 111127309 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
E 111115556 BRCA1-associated RING domain protein 1-like isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 111118511 BRISC and BRCA1-A complex member 1-like K20776 BABAM; BRISC and BRCA1-A complex member 1
E 111118616 BRISC and BRCA1-A complex member 1-like K20776 BABAM; BRISC and BRCA1-A complex member 1
E 111128431 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
E 111099585 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 111136867 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D BRCA1-C complex
E 111121058 uncharacterized protein LOC111121058 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 111120092 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 111127260 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 111127309 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E 111128268 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 111128268 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 111130364 DNA repair protein RAD51 homolog 2-like K10869 RAD51L1; RAD51-like protein 1
E 111137092 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 111137193 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 111125868 LOW QUALITY PROTEIN: DNA repair protein XRCC2-like K10879 XRCC2; DNA-repair protein XRCC2
E 111130117 DNA repair protein XRCC3-like K10880 XRCC3; DNA-repair protein XRCC3
E 111130234 DNA repair protein XRCC3-like K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 111136966 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 111117581 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 111107910 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 111132146 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 111121715 DNA repair and recombination protein RAD54B-like isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
E 111121716 DNA repair and recombination protein RAD54B-like isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 111126010 ATP-dependent DNA helicase Q-like SIM K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 111129935 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 111130258 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 111112348 Werner syndrome ATP-dependent helicase-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 111115333 Werner syndrome ATP-dependent helicase-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 111130645 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111131048 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111102809 ATP-dependent DNA helicase Q-like 3 isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111136551 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q4-like K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 111124294 ATP-dependent DNA helicase Q5-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 111130645 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111131048 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111102809 ATP-dependent DNA helicase Q-like 3 isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111113980 DNA topoisomerase 3-beta-1-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 111119126 uncharacterized protein LOC111119126 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E 111134654 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 111120888 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 111126776 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 111134690 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 111135584 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 111135380 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 111129953 serine/threonine-protein phosphatase 4 regulatory subunit 3A-like K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 111129956 serine/threonine-protein phosphatase 4 regulatory subunit 3A-like K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 111131871 serine/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 111131470 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 111129886 AP-5 complex subunit mu-1-like K19023 AP5M1; AP-5 complex subunit mu-1
E 111135298 AP-5 complex subunit sigma-1-like K19024 AP5S1; AP-5 complex subunit sigma-1
E 111118342 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
E 111118550 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 111130482 structural maintenance of chromosomes protein 5-like K22803 SMC5; structural maintenance of chromosomes protein 5
E 111130622 structural maintenance of chromosomes protein 5-like K22803 SMC5; structural maintenance of chromosomes protein 5
E 111118920 structural maintenance of chromosomes protein 6-like isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 111121131 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 111135650 E3 SUMO-protein ligase nse2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 111108522 non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 111099442 EP300-interacting inhibitor of differentiation 3-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 111099443 EP300-interacting inhibitor of differentiation 3-like isoform X1 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 111137214 uncharacterized protein LOC111137214 isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
D Other HR factors
E 111120979 crossover junction endonuclease EME1-like isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 111132560 exonuclease 3'-5' domain-containing protein 2-like K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 111131667 crossover junction endonuclease MUS81-like isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 111125990 26S proteasome complex subunit SEM1-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 111125660 DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3
E 111100611 swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 111130950 structure-specific endonuclease subunit slx1-like K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 111130120 LOW QUALITY PROTEIN: spatacsin-like K19026 SPG11; spatacsin
E 111128054 LOW QUALITY PROTEIN: mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 111132399 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111134047 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111134907 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111136499 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111099139 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111136962 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111136963 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111136964 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111136965 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111138247 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 111138499 uncharacterized protein LOC111138499 isoform X1 K22806 SPIDR; DNA repair-scaffolding protein
E 111120614 protein C21orf2-like K23456 CFAP410; cilla- and flagella-associated protein
E 111120130 protein C21orf2-like K23456 CFAP410; cilla- and flagella-associated protein
E 111112299 LOW QUALITY PROTEIN: hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 111132070 zinc finger SWIM domain-containing protein 7-like K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 111136248 LOW QUALITY PROTEIN: BRCA2-interacting transcriptional repressor EMSY-like K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 111129794 LOW QUALITY PROTEIN: heat shock factor 2-binding protein-like K25791 HSF2BP; heat shock factor 2-binding protein
E 111136054 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 111136493 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 111119646 LOW QUALITY PROTEIN: PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 111129829 X-ray repair cross-complementing protein 5-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 111104153 LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 5-like K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 111119812 LOW QUALITY PROTEIN: DNA-dependent protein kinase catalytic subunit-like K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 111120092 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 111127260 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 111127309 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 111121647 LOW QUALITY PROTEIN: DNA ligase 4-like K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 111132242 DNA repair protein XRCC4-like isoform X1 K10886 XRCC4; DNA-repair protein XRCC4
E 111133337 non-homologous end-joining factor 1-like K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 111135834 DNA polymerase lambda-like isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 111133963 DNA-directed DNA/RNA polymerase mu-like K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 111134792 DNA-directed DNA/RNA polymerase mu-like isoform X1 K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 111120810 DNA polymerase beta-like isoform X1 K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 111136704 aprataxin-like isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 111105836 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 111106142 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 111119057 LOW QUALITY PROTEIN: tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 111103494 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 111123252 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 111102211 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 111131275 LOW QUALITY PROTEIN: uncharacterized protein LOC111131275 K25772 PAXX; protein PAXX
C FA (Fanconi anemia) pathway
D FA core complex
E 111138268 Fanconi anemia group A protein homolog K10888 FANCA; fanconi anemia group A protein
E 111123508 uncharacterized protein LOC111123508 K10893 FANCF; fanconi anemia group F protein
E 111127006 uncharacterized protein LOC111127006 K10893 FANCF; fanconi anemia group F protein
E 111133998 E3 ubiquitin-protein ligase FANCL-like isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 111122179 Fanconi anemia core complex-associated protein 24-like K10898 FAAP24; fanconi anemia-associated protein
D FA core complex binding factors
E 111132480 protein deadpan-like K06054 HES1; hairy and enhancer of split 1
E 111133867 uncharacterized protein LOC111133867 isoform X1 K06054 HES1; hairy and enhancer of split 1
E 111135582 transcription factor HES-1-B-like K06054 HES1; hairy and enhancer of split 1
E 111099184 transcription factor HES-4-like K06054 HES1; hairy and enhancer of split 1
E 111138134 enhancer of split m3 protein-like K06054 HES1; hairy and enhancer of split 1
E 111138170 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 111126926 centromere protein S-like K11511 APITD1; centromere protein S
E 111118366 centromere protein X-like K15360 STRA13; centromere protein X
E 111101024 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
E 111103839 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 111130645 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111131048 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111102809 ATP-dependent DNA helicase Q-like 3 isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 111113980 DNA topoisomerase 3-beta-1-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 111119126 uncharacterized protein LOC111119126 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
E 111107067 Fanconi anemia group D2 protein-like K10891 FANCD2; fanconi anemia group D2 protein
E 111100339 Fanconi anemia group I protein-like isoform X1 K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 111136867 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 111127948 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 111128021 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 111128268 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 111102631 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 111102874 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 111120595 WD repeat-containing protein 48-like K15361 WDR48; WD repeat-containing protein 48
E 111108030 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 111108150 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 111128387 WD repeat-containing protein 48-like K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 111126639 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 111126797 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 111103377 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 6 regulatory subunit 3-like K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 111112526 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
D Ubiquitin ligases
E 111129090 E3 ubiquitin-protein ligase RNF8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 111129091 E3 ubiquitin-protein ligase RNF8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 111127220 E3 ubiquitin-protein ligase HERC2-like isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
E 111127369 E3 ubiquitin-protein ligase HERC2-like isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 111135461 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
E 111121099 WD repeat-containing protein 70-like K24752 WDR70; WD repeat-containing protein 70
E 111119066 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 111131835 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 111128959 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 111128124 DNA polymerase iota-like isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 111129379 DNA polymerase iota-like K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 111131160 DNA polymerase kappa-like isoform X1 K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 111130580 DNA repair protein REV1-like isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
D 111134136 DNA polymerase nu-like isoform X1 K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 111126209 ubiquitin-conjugating enzyme E2 A isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 111130529 helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 111131800 helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 111137617 ubiquitin-conjugating enzyme E2 variant 1-like K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 111110185 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 111120673 proliferating cell nuclear antigen-like isoform X1 K04802 PCNA; proliferating cell nuclear antigen
D 111119646 LOW QUALITY PROTEIN: PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
D 111124760 HMG box-containing protein C19G7.04-like K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 111136545 cell cycle checkpoint control protein RAD9A-like K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 111110332 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 111119252 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 111133654 LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 111118434 cell cycle checkpoint protein RAD17-like K06662 HRAD17; cell cycle checkpoint protein
D 111119024 cell cycle checkpoint protein RAD17-like K06662 HRAD17; cell cycle checkpoint protein
D 111132381 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 111134900 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 111135799 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 111122897 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 111137687 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 111133654 LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD1-like K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 111135160 LOW QUALITY PROTEIN: protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
C Triple T complex
D 111102631 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 111102874 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 111138486 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 111128215 TELO2-interacting protein 2-like K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 111109509 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 111117985 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 111129910 serine/threonine-protein kinase ATR-like isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 111107373 LOW QUALITY PROTEIN: ATR-interacting protein-like K10905 ATRIP; ATR interacting protein
D 111135770 serine-protein kinase ATM-like K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 111132497 LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 111132498 LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 111134476 serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 111132091 M-phase inducer phosphatase 1-like K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
D 111106831 M-phase inducer phosphatase-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 111132581 M-phase inducer phosphatase 2-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 111132582 M-phase inducer phosphatase-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 111135070 M-phase inducer phosphatase-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 111132547 M-phase inducer phosphatase 1-B-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 111132548 M-phase inducer phosphatase 3-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 111132549 M-phase inducer phosphatase 1-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 111132550 M-phase inducer phosphatase-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 111132551 M-phase inducer phosphatase-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 111132042 14-3-3 protein homolog 2-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 111138449 14-3-3 protein homolog 2-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 111128699 14-3-3-like protein 2 isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 111136452 14-3-3 protein homolog 2-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 111136586 14-3-3 protein homolog 2-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 111135475 14-3-3 protein epsilon-like K06630 YWHAE; 14-3-3 protein epsilon
D 111137632 14-3-3 protein epsilon-like K06630 YWHAE; 14-3-3 protein epsilon
D 111105116 wee1-like protein kinase 1-A K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 111120025 mediator of DNA damage checkpoint protein 1-like isoform X1 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 111106859 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 111107096 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 111125488 serine/threonine-protein kinase Nek1-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 111125854 serine/threonine-protein kinase Nek1-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 111114585 serine/threonine-protein kinase Nek10-like isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 111115138 serine/threonine-protein kinase Nek10-like isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 111136925 serine/threonine-protein kinase Nek11-like isoform X1 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 111104642 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 111138412 schlafen family member 13-like K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]
D 111111648 vacuolar protein sorting-associated protein 4-like isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 111135601 vacuolar protein sorting-associated protein 4-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 111130617 LOW QUALITY PROTEIN: protein SDE2 homolog K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 111100739 LOW QUALITY PROTEIN: DNA polymerase theta-like K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 111137181 LOW QUALITY PROTEIN: myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 111119563 DNA-directed primase/polymerase protein-like isoform X1 K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 111106464 5' exonuclease Apollo-like isoform X1 K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 111106809 5' exonuclease Apollo-like K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 111099106 exonuclease V-like isoform X1 K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 111123536 endonuclease V-like K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 111127724 DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 111131280 ankyrin repeat and LEM domain-containing protein 1-like K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 111100588 helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 111121653 DNA excision repair protein ERCC-6-like 2 isoform X1 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 111132870 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 111138391 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 111103801 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 111133056 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 111133226 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 111126234 pleiotropic regulator 1-like K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 111118210 7,8-dihydro-8-oxoguanine triphosphatase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 111101814 8-oxo-dGDP phosphatase NUDT18-like isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 111105981 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111105982 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111108617 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111109808 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111124500 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 111127434 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 111122251 ribonucleoside-diphosphate reductase small chain-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 111118358 ribonucleoside-diphosphate reductase small chain-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 111121007 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 111118907 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 111100499 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 111133661 uncharacterized protein LOC111133661 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 111114668 uncharacterized protein LOC111114668 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 111120573 uncharacterized protein LOC111120573 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 111119714 uncharacterized protein LOC111119714 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 111118241 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
F 111107947 uncharacterized protein LOC111107947 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111108289 uncharacterized protein LOC111108289 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111122248 uncharacterized protein LOC111122248 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111109182 uncharacterized protein LOC111109182 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111123707 Werner syndrome ATP-dependent helicase-like K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111124949 uncharacterized protein LOC111124949 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111112946 uncharacterized protein LOC111112946 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111113419 uncharacterized protein LOC111113419 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111113452 uncharacterized protein LOC111113452 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111114469 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111099201 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111115096 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111116012 ATP-dependent DNA helicase Q-like SIM K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111117547 uncharacterized protein LOC111117547 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111100649 ATP-dependent DNA helicase Q-like 1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111100707 uncharacterized protein LOC111100707 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111101830 ATP-dependent DNA helicase RecQ-like isoform X1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111103492 uncharacterized protein LOC111103492 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F 111119552 ATP-dependent DNA helicase RecQ-like isoform X1 K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 111105981 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111105982 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111108617 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 111109808 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024